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Displaying drugs 101 - 125 of 2353 in total

GTP-506

GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … .WPRE.bGH and AAVrh79.hHDR.TBG.hOTCco.bGH ... Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9 …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …

Anbenitamab

Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …

Antihemophilic factor human

Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … Factor VIII, but does not contain the B-domain, which has no known biological function and [DB11607] ... as a result, leads to easy bruising and bleeding. ... results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of fibrinogen …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Octanate 500IU Powder and Solvent for Solution for Injection ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octanate 250IU Powder and Solvent for Solution for Injection …

Cabazitaxel

Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and ... cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) …

CVac

Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …

AMG 424

AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …

NTLA-2002

NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …

Von Willebrand factor human

The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … and hemophilia A. ... vessel injury and stabilizing procoagulant factor VIII (FVIII). ... It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Bismuth subsalicylate

Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Synonyms: … Pink bismuth …
Matched Description: … [A230728, A230773] Bismuth subsalicylate was first approved by the FDA in 1939 and is now mainly used ... Bismuth subsalicylate is an antacid and anti-diarrheal agent. ... to relieve nausea, diarrhea, and gastrointestinal discomfort. …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go ... Bismuth Subsalicylate/Metronidazole/Tetracycline Hydrochloride …
Matched Categories: … Antacids and Adsorbents …
Matched Products: … Green Relief ... Up and Up Stomach Relief ... Up and Up Digestive Relief …

Doxylamine

Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Approved
Vet approved
Matched Synonyms: … N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine ... Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether …
Matched Description: … It is used in allergies and as an antitussive, antiemetic, and hypnotic. ... Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism …
Matched Mixtures name: … Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine Succinate and Pyridoxine Hydrochloride …
Matched Products: … Berkley and Jensen Sleep Aid ... Up and Up Nighttime Sleep Aid ... HOGGAR N …

Cyclomethicone 5

Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and ... Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
Matched Products: … Mefactory Super Clear Lip And Eye Remover ... 3ce Pink Im Good Mascara …

Sarocladium strictum

Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Mixtures name: … New Stock Fungi Mix ... New Stock Fungi Mix ... New Stock Fungi Mix …
Matched Categories: … Non-Standardized Food Allergenic Extract ... Non-Standardized Fungal Allergenic Extract …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …

Cetylpyridinium

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Description: … plaque and reducing gingivitis. ... found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and ... In these products, it generally mediates an antiseptic activity and protective action against dental …
Matched Mixtures name: … Green Antiseptic Mwh & Gargle ... BUCOSEPTOL N ... Emercreme No4 Ont Efa …
Matched Categories: … Antiseptics and Disinfectants ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Mouthwashes and Gargles …
Matched Products: … NEO FORMITROL ... VICKS MEDICATED DROPS (GREEN APPLE) ... NEO CORICIDIN GOLA …

Chlorine dioxide

Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Products: … Disinfectant and Sanitizer ... Skin N Clean …

Starch, corn

Corn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. Starch...
Approved
Nutraceutical
Matched Description: … polymer of glucose in the form of amylose and amylopectin. ... starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and ... Corn starch may be added in some food products as a thickening agent or anti-caking agent, and is sometimes …
Matched Products: … Soothe and Cool Non-Caking Body ... Lotrimin Daily Sweat and Odor Control …

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …

Chenopodium album pollen

Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Categories: … Non-Standardized Pollen Allergenic Extract …
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …

Olopatadine

Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … tolerability profile since it does not cause perturbation of cell membranes. ... inflammatory and allergic reactions. ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. …
Matched Salts name: … Olopatadine hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Histamine H1 Antagonists, Non-Sedating …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief ... PALLADA-NS %6.65 MG/ML NAZAL SPREY, 30 ML …

Spanlecortemlocel

Investigational
Matched Synonyms: … Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and ... ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Feiba Nf ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …

Viagenpumatucel-L

Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine …
Matched Description: … investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small …

TN-201

TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
Matched Synonyms: … Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Salts name: … Labetalol hydrochloride …
Matched Categories: … Alpha and Beta Blocking Agents and Thiazides ... Alpha and Beta Blocking Agents ... Beta Blocking Agents and Thiazides ... labetalol and thiazides ... labetalol and other diuretics …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) ... Labetalol Hydrochloride ... Labetalol hydrochloride …

Synthetic camphor

Approved
Experimental
Matched Mixtures name: … Green Leaf Cbd Ultra Relief ... Green Bamboo ... Eagle Green Balm …
Matched Products: … Arthritis and Joint Pain Relief Thayers ... Sore No More Warm Therapry Plus CBD 2000mg ... Weeks and Leo Medicated Vaporizing Steam …

Atacicept

Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 101 - 125 of 2353 in total