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Displaying drugs 101 - 125 of 742 in total

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …

TVI-Brain-1

Investigational
Matched Synonyms: … Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination …

Nendratareotide uzatansine

Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …

Cetylpyridinium

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Description: … plaque and reducing gingivitis. ... found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and ... In these products, it generally mediates an antiseptic activity and protective action against dental …
Matched Mixtures name: … Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System ... Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System ... QCare Oral Cleansing and Suctioning System, Q4 …
Matched Categories: … Antiseptics and Disinfectants ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Mouthwashes and Gargles …
Matched Products: … Colgate Swish Mild Mint ... Qcare Oral Cleansing and Suctioning System ... SmartMouth Gum and Plaque Formula …

VOR33

VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …

Spanlecortemlocel

Investigational
Matched Synonyms: … Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and ... ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG ... BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …

Fibrinogen human

Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion …

Carbidopa

Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …

Dendryphiella vinosa

Dendryphiella vinosa is a fungus which can provoke allergic reactions. Dendryphiella vinosa extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release …
Matched Products: … Molds, Rusts and Smuts, Helminthosporium interseminatum …

Atacicept

Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Povidone-iodine

Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … Shelanski and M. V. Shelanski. ... Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic …
Matched Mixtures name: … Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System ... Frepp Sepp Kit ... Frepp Sepp Kit …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … 3M Skin and Nasal Antiseptic ... Antiseptic Patient Preoperative Skin Preparation and Surgical Hand Scrub ... ERPHA-SEPTAN …

Mesocricetus auratus skin

Mesocricetus auratus skin or pelt is used in allergenic testing.
Approved
Matched Synonyms: … hamster skin extract ... Syrian hamster skin extract …
Matched Name: … Mesocricetus auratus skin …
Matched Description: … Mesocricetus auratus skin or pelt is used in allergenic testing. …
Matched Categories: … Increased Histamine Release ... Non-Standardized Animal Skin Allergenic Extract …
Matched Products: … Hamster Hair and Epithelia …

Cod, unspecified

Cod, unspecified allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release …
Matched Products: … Food - Fish and Shellfish, Codfish Gadus callarias …

CVac

Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …

AMG 424

AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …

NTLA-2002

NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …

Phoma exigua var. exigua

Phoma exigua var. exigua is a fungus which can provoke allergic reactions. Phoma exigua var. exigua extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release …
Matched Products: … Molds, Rusts and Smuts, Phoma herbarum …

Lobster

Lobster allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release …
Matched Products: … Food - Fish and Shellfish, Lobster Homarus americanus …

Anbenitamab

Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …

Botrytis cinerea

Botrytis cinerea is a fungus which can provoke allergic reactions. Botrytis cinerea extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release …
Matched Products: … Molds, Rusts and Smuts, Botrytis cinerea …

Cochliobolus spicifer

Cochliobolus spicifer is a fungus which can provoke allergic reactions. Cochliobolus spicifer extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release …
Matched Products: … Molds, Rusts and Smuts, Curvularia spicifera …

Varicella zoster vaccine (recombinant)

Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Description: … through the nerve cells to the surface of the skin where it causes a painful blistering rash. ... efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients ... First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine …
Matched Products: … SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5ML …

Perfluorooctane

Experimental
Matched Products: … SONAZOID POWDER AND SOLVENT FOR DISPERSION FOR INJECTION 16 MICROLITRE PER VIAL …
Displaying drugs 101 - 125 of 742 in total