Displaying drugs 126 - 150 of 590 in total
Tapinarof
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Matched Synonyms: … 3,5-Dihydroxy-4-isopropyl-trans-stilbene …
AFM-13
Investigational
Matched Synonyms: … Recombinant antibody construct against human CD30 and CD16A …
Phenol
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Phenyl alcohol ... Phenylic alcohol …
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... Poison Oak and Ivy ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... Poison Oak and Ivy ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Diphenhydramine
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Zzzquil Alcohol Free ... Nighttime Sleep Aid Alcohol Free ... ZzzQuil Alcohol Free Nighttime Sleep-Aid …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Zzzquil Alcohol Free ... Nighttime Sleep Aid Alcohol Free ... ZzzQuil Alcohol Free Nighttime Sleep-Aid …
VA-MENGOC-BC®
VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C. As there already exists a polysaccharide-based vaccine against meningococcal disease originating from serogroups A,C,W135, and...
Investigational
Matched Synonyms: … Meningococcal polysaccharide vaccine groups B and C …
Matched Description: … VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. ... The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide ... Y, this vaccine was created for use against serogroups B and C. …
Matched Description: … VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. ... The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide ... Y, this vaccine was created for use against serogroups B and C. …
Taliglucerase alfa
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational
Matched Synonyms: … Taliglucerase alfa …
Matched Name: … Taliglucerase alfa …
Matched Description: … Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase ... It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's …
Matched Categories: … taliglucerase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Taliglucerase alfa …
Matched Description: … Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase ... It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's …
Matched Categories: … taliglucerase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Efprezimod alfa
CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.
Investigational
Matched Synonyms: … Human CD24 and human IgG Fc Fusion Protein …
Matched Name: … Efprezimod alfa …
Matched Name: … Efprezimod alfa …
Famotidine
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … gastroesophageal reflux disease (GERD), in adults and children. ... [A189462] Famotidine is used in various over-the-counter and off-label uses. ... It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and …
Matched Mixtures name: … Ibuprofen and famotidine ... Ibuprofen and Famotidine ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Famotidine Omega -(with Preservative,benzyl Alcohol) ... Up and Up Famotidine ... Berkley and Jensen Famotidine …
Matched Mixtures name: … Ibuprofen and famotidine ... Ibuprofen and Famotidine ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Famotidine Omega -(with Preservative,benzyl Alcohol) ... Up and Up Famotidine ... Berkley and Jensen Famotidine …
Octyldodecanol
Experimental
Matched Synonyms: … 2-Octyldodecyl alcohol …
Matched Categories: … Alcohols …
Matched Categories: … Alcohols …
Coagulation factor VIIa Recombinant Human
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Synonyms: … Eptacog alfa ... Eptacog alfa (activated) …
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Andexanet alfa
Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Synonyms: … Andexanet alfa …
Matched Name: … Andexanet alfa …
Matched Description: … Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical ... Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous ... containing Gla: via this truncation, andexanet alfa is unable to bind to membrane surfaces and assemble …
Matched Categories: … andexanet alfa ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Andexanet alfa …
Matched Description: … Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical ... Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous ... containing Gla: via this truncation, andexanet alfa is unable to bind to membrane surfaces and assemble …
Matched Categories: … andexanet alfa ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
CAM-GM201
Investigational
Matched Synonyms: … rAAV2/1 Hex alpha and beta ... Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta …
KL1333
Investigational
Matched Synonyms: … 2-isopropyl-3h-naphtho(1,2-d)imidazole-4,5-dione ... 2-isopropyl-3H-naphtho[1,2-d]imidazole-4,5-dione …
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Conestat alfa …
Matched Name: … Conestat alfa …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact …
Matched Categories: … conestat alfa ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Name: … Conestat alfa …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact …
Matched Categories: … conestat alfa ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Susoctocog alfa …
Matched Name: … Susoctocog alfa …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this …
Matched Categories: … susoctocog alfa ... Blood and Blood Forming Organs …
Matched Name: … Susoctocog alfa …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this …
Matched Categories: … susoctocog alfa ... Blood and Blood Forming Organs …
Efmoroctocog alfa
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Efmoroctocog alfa …
Matched Name: … Efmoroctocog alfa …
Matched Description: … Other drug products with similar structure and function to Efmoroctocog alfa include [DB13999], which ... Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. …
Matched Name: … Efmoroctocog alfa …
Matched Description: … Other drug products with similar structure and function to Efmoroctocog alfa include [DB13999], which ... Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. …
Beroctocog alfa
Approved
Investigational
Matched Name: … Beroctocog alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pegvorhyaluronidase alfa
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … Pegvorhyaluronidase alfa ... (36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA …
Matched Name: … Pegvorhyaluronidase alfa …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single ... Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). …
Matched Categories: … Enzymes and Coenzymes …
Matched Name: … Pegvorhyaluronidase alfa …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single ... Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). …
Matched Categories: … Enzymes and Coenzymes …
Pabinafusp alfa
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Pabinafusp alfa ... receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa …
Matched Name: … Pabinafusp alfa …
Matched Description: … Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With …
Matched Name: … Pabinafusp alfa …
Matched Description: … Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With …
Alunacedase alfa
Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Investigational
Matched Synonyms: … Alunacedase alfa …
Matched Name: … Alunacedase alfa …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Alunacedase alfa …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Agalsidase alfa
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … Agalsidase alfa ... Agalsidase alfa (genetical recombination) …
Matched Name: … Agalsidase alfa …
Matched Description: … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. ... [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413] ... [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after …
Matched Categories: … agalsidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Name: … Agalsidase alfa …
Matched Description: … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. ... [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413] ... [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after …
Matched Categories: … agalsidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … Onfekafusp alfa …
Matched Name: … Onfekafusp alfa …
Matched Description: … Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal …
Matched Name: … Onfekafusp alfa …
Matched Description: … Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Efineptakin alfa …
Matched Name: … Efineptakin alfa …
Matched Description: … Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that ... Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Efineptakin alfa …
Matched Description: … Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that ... Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Efmitermant alfa
Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial NCT03124459 (Study of ACE-083 in Patients With Charcot-marie-tooth Disease).
Investigational
Matched Name: … Efmitermant alfa …
Matched Description: … Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial …
Matched Description: … Efmitermant alfa, a locally-acting GDF/activin ligand trap, is under investigation in clinical trial …
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Cipaglucosidase alfa …
Matched Name: … Cipaglucosidase alfa …
Matched Description: … ] and [avalglucosidase alfa]. ... be granted marketing authorization for the treatment of Pompe disease,[L45275] and the EMA fully approved ... Compared to alglucosidase alfa, cipaglucosidase alfa has a higher M6P content. …
Matched Categories: … cipaglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Cipaglucosidase alfa …
Matched Description: … ] and [avalglucosidase alfa]. ... be granted marketing authorization for the treatment of Pompe disease,[L45275] and the EMA fully approved ... Compared to alglucosidase alfa, cipaglucosidase alfa has a higher M6P content. …
Matched Categories: … cipaglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Displaying drugs 126 - 150 of 590 in total