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Displaying drugs 451 - 475 of 598 in total

Tolbutamide

Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 1-Butyl-3-(p-tolylsulfonyl)urea ... 1-Butyl-3-(p-methylphenylsulfonyl)urea ... N-Butyl-N'-(p-tolylsulfonyl)urea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … Tolbutamide and its metabolites are excreted in urine (75-85%) and feces. ... It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea ... increase the number and sensitivity of insulin receptors. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Glycerol 2-phosphate

Experimental
Matched Name: … Glycerol 2-phosphate …

Oxygen

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … Oxygen is an element displayed by the symbol O, and atomic number 8. ... any disease that impairs the body's ability to take up and use gaseous oxygen. ... Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. …
Matched Products: … OSSIGENO FARMA GAS MEDICAL AND TECHNICAL GASES …

Imidocarb

Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
Vet approved
Matched Synonyms: … 1,3-bis(3-(2-imidazolin-2-yl)phenyl)urea ... N,N'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea …
Matched Iupac: … 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea …
Matched Description: … of infection with Babesia and other parasites. ... Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment …

Kaolin

Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was the active substance of anti-diarrhoea medicine Kaopectate.
Approved
Matched Description: … as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and …
Matched Mixtures name: … Kaolin and Pectin Susp …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Look At Me Mud Face Mask Mini Pack Aloe …

Chlormerodrin

Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Approved
Withdrawn
Matched Synonyms: … 1-[3-(chloromercuri)-2-methoxypropyl]urea …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Matched Description: … The radiolabeled form has been used as a diagnostic and research tool. ... It is no longer used and has been replaced with new classes of diuretic drugs. …

Rabies virus inactivated antigen, B

Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins …
Matched Products: … RABIES VACCINE FOR HUMAN USE (VERO CELL), FREEZE-DRIED FINAL BULK …

(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate

Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …

Echinacea angustifolia root

Approved
Experimental
Matched Synonyms: … Narrow-leaf echinacea root ... Narrow-leaf purple coneflower root …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg ... TANTUM VERDE GOLA …

Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and ... It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane ... causing intracellular components to leak from bacterial cells. …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... tetracycline and oleandomycin ... Ophthalmological and Otological Preparations ... Antiinfectives and Antiseptics for Local Oral Treatment ... lansoprazole, tetracycline and metronidazole …
Matched Products: … MeaStem First Aid and Antibiotic …

AT9283

AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.
Investigational
Matched Synonyms: … 1-Cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-urea …
Matched Description: … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid …

Glisoxepide

Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide,...
Investigational
Matched International brands: … Glysepin …
Matched Description: … transporter, by the loop diuretic bumetanide, by 4,4'-diisothiocyano-2,2'-stilbenedisulfonate (DIDS) and …
Matched Categories: … Alimentary Tract and Metabolism …

Ketotifen

Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief …

L-Dilinoleoyllecithin

Experimental
Matched Synonyms: … 1,2-dilinoleoyl-sn-glycero-3-phosphocholine ... 1,2-di-O-linoleoyl-sn-glycero-3-phosphocholine ... 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine …

SNS-314

SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis, leading to multiple rounds of endoreduplication and eventually cell death. SNS-314 inhibits tumor growth in a variety of preclinical models, and...
Investigational
Matched Synonyms: … 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Iupac: … 1-(3-chlorophenyl)-3-{5-[2-({thieno[3,2-d]pyrimidin-4-yl}amino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis …

Bazlitoran

Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

NS-3728

NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Synonyms: … N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …

LP-184

Investigational
Matched Synonyms: … N-HYDROXY-N-(METHYLACYLFULVENE)UREA ... HYDROXY-1-((6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXO-6',7'-DIHYDROSPIRO(CYCLOPROPANE-1,5'-INDEN)-3'-YL)METHYL)UREA ... UREA, N-(((6'R)-6',7'-DIHYDRO-6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXOSPIRO(CYCLOPROPANE-1,5'-(5H)INDEN)- …
Matched Iupac: … (6'R)-6'-hydroxy-2',4',6'-trimethyl-7'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-inden]-3'-yl]methyl}urea …

BS-001

BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human use (rHSV2hGM-CSF).
Investigational
Matched Synonyms: … Recombinant Oncolytic Herpes Simplex Virus Type II (OH2) Therapeutic Injection (Vero Cell) for Human …
Matched Description: … BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell …

2-phospho-D-glyceric acid

A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Experimental
Matched Name: … 2-phospho-D-glyceric acid …
Matched Description: … A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration. …

3-phospho-D-glyceric acid

Experimental
Matched Name: … 3-phospho-D-glyceric acid …

Dideoxyadenosine

Investigational
Matched Synonyms: … -d-glycero-pentofuranosyl)purine ... -d-glycero-pentofuranosyl)-9h-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Rumex crispus top

Rumex crispus top allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Rumex crispus flower/leaf/stem extract …

Zinc gluconate

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … of common colds and with decreased symptom severity. ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration ... salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for …
Matched Mixtures name: … Zinc and Algin Tab Nu Life ... Multivitamin and Mineral ... Cal-mag Vitamin C and Zinc Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … ZINK VERLA 10MG ... ZINK VERLA OTC 20MG …
Displaying drugs 451 - 475 of 598 in total