Displaying drugs 4776 - 4800 of 11854 in total
AICA ribonucleotide
5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. AICAR has been used clinically to treat and protect against cardiac ischemic injury. The drug was first used in the 1980s as...
Experimental
Investigational
Matched Description: … is currently of interest as a potential treatment for diabetes by increasing the metabolic activity ... The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and …
Carbopol 974P
Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. The compound,...
Investigational
Matched Description: … a broad-spectrum mechanism based on acidification of pathogens. ... Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with ... It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sulforaphane
Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Investigational
Matched Description: … It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Triacetin
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Vitex agnus-castus fruit extract
Vitex agnus-castus fruit extract is obtained from dry fruits of Vitex agnus-castus. The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally resemble sex hormones. Clinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast...
Experimental
QXL138AM
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Description: … QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused …
Lithium cation
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Experimental
Matched Description: … displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several ... It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. ... The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily …
Cp-Coeleneterazine
Experimental
Matched Iupac: … cyclopentylmethyl)-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-2H,3H,7H,8H-imidazo[1,2-a] …
I-Coeleneterazine
Experimental
Matched Iupac: … (2S,8R)-8-benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-[(4-iodophenyl)methyl]-2H,3H,7H,8H-imidazo[1,2-a] …
cis-Diamminechlorocholylglycinateplatinum(II)
Experimental
Matched Iupac: … platinum(2+) 2-[(1-oxido-4-{4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …
Vamotinib
Vamotinib (PF-114) is under investigation in clinical trial NCT02885766 (Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene).
Investigational
Matched Iupac: … 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-(2-{[1,2,4]triazolo[4,3-a] …
ORG-31710
ORG-31710 is a progestational hormone antagonist.
Experimental
Matched Iupac: … -[4-(dimethylamino)phenyl]-5,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,10,11,11a-dodecahydrospiro[cyclopenta[a] …
Matched Description: … ORG-31710 is a progestational hormone antagonist. …
Matched Description: … ORG-31710 is a progestational hormone antagonist. …
Dihydroxyaluminum sodium carbonate
Experimental
Nendratareotide uzatansine
Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Description: … Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated …
Aspartic Acid-4-Carboxymethyl Ester
Experimental
Icaridin
Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. Piperidines are structural components of piperine, which is a plant extract from the genus _Piper _, or pepper. Icaridin has been commonly used as a topically-applied insect repellent...
Experimental
Matched Description: … and a member of the piperidine chemical family. ... Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine ... Piperidines are structural components of [piperine], which is a plant extract from the genus _Piper _ …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
TTX-MC138
TTX-MC138 is an antisense oligonucleotide targeting miR-10b. It is under investigation for the treatment of various metastatic cancers.
Investigational
Manitimus
FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
Investigational
Matched Iupac: … (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]hept-2-en-6-ynamide …
Matched Description: … kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy. ... FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in …
Matched Description: … kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy. ... FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in …
Ciclonium bromide
Experimental
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
4-Carboxycinnamic Acid
Experimental
Acridine Carboxamide
Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.
Investigational
Salicylamide O-acetic acid
Experimental
alpha-D-glucopyranosyl-2-carboxylic acid amide
Experimental
CHF5633
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Description: … ), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic ... CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine …
7-methyl-guanosine-5'-triphosphate-5'-guanosine
Experimental
Displaying drugs 4776 - 4800 of 11854 in total