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Displaying drugs 26 - 50 of 15168 in total
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … Ofloxacin S-(-)-form ... (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine ... (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin ... Metabolic Side Effects of Drugs and Substances …
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 …
Matched Description: … and corneal trauma. ... It has been approved by FDA for use in externally applied drugs and cosmetics. ... A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline …
Matched Mixtures name: … Minims Lidocaine and Fluorescein ... Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Indicators and Reagents …
5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, and...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 5-hydroxytryptophan L-form
Matched Description: … suppressant, and sleep aid, and is also marketed in many European countries for the indication of major ... 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and ... metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Synonyms: … D-Glucose in linear form
Matched Description: … [T28] The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation ... through aerobic or anaerobic respiration and fermentation. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and
Matched Mixtures name: … Ringers and Dextrose ... Ionosol and Dextrose ... Plasma-Lyte 148 and dextrose …
Matched Categories: … Diet, Food, and Nutrition …
Approved
Investigational
Matched Synonyms: … Methyl vitamin B12 ... Methyl(III)cobalamin …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions. It is derived from sources such as turpentine, oregano, thyme and eucalyptus. It was popular in the United States since the late nineteenth century, but...
Approved
Experimental
Matched Synonyms: … Terpin cis-form hydrate …
Matched Description: … with acute or chronic bronchitis, and related pulmonary conditions. ... It is derived from sources such as turpentine, oregano, thyme and eucalyptus. ... Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting …
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Synonyms: … Pseudoephedrine D-form
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and
Matched Mixtures name: … Up and Up Cold and Sinus ... Up and Up Sinus and Cold D ... Up and Up allergy and congestion relief …
Matched Categories: … Alpha-and Beta-adrenergic Agonists …
Matched Products: … Up and Up Suphedrine ... Up and Up Sinus 12 Hour ... UP AND UP nasal decongestant …
A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Approved
Nutraceutical
Matched Synonyms: … 2-Methyl-1,4-naphthochinon ... 2-Methyl-1,4-Naphthalenedione ... 2-Methyl-1,4-naphthoquinone …
Matched Iupac: … 2-methyl-1,4-dihydronaphthalene-1,4-dione …
Matched Description: … A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition …
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and...
Approved
Matched Synonyms: … 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide …
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Description: … proteins which are necessary for bacterial growth and division, and using them in conjunction helps ... these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and ... for the treatment of a variety of bacterial infections, including those of the urinary, respiratory, and
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Categories: … Sulfonamides and trimethoprim ... sulfamethoxazole and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine …
Matched Products: … Sulfamethoxazole and Trimethoprim …
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and
Matched Mixtures name: … AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan ... Amlodipine and Valsartan …
Matched Categories: … losartan and amlodipine ... ramipril and amlodipine ... nebivolol and amlodipine ... aliskiren and amlodipine ... valsartan and amlodipine …
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) …
Matched Description: … as the endogenously available form. ... then isolated, the human form is isolated from pooled human plasma. ... Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of …
Matched Categories: … Blood and Blood Forming Organs …
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … (±)-2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate ... 2-methyl-2-propyltrimethylene carbamate isopropylcarbamate ... N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Description: … acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and ... itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and
Matched Mixtures name: … Carisoprodol and Aspirin ... Carisoprodol and Aspirin ... Carisoprodol and Aspirin …
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and ... Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal …
Matched Categories: … Alimentary Tract and Metabolism …
A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Approved
Matched Synonyms: … 5-Methyl-2-(1-Methylethyl)Phenol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …
Matched Description: … It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as …
Matched Mixtures name: … Royal Mouthwash Fresh and Clean Original Mint ... Neobun Medicated Plaster with Ginger and Lemongrass Oil Aroma ... Eucalyptol, menthol, methyl salicylate, thymol …
An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Approved
Matched Synonyms: … 2-methyl-2-ethylsuccinimide ... 3-methyl-3-ethylsuccinimide ... α-methyl-α-ethylsuccinimide …
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Synonyms: … L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid …
Matched Description: … Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. ... It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... 5-Allyl-1-methyl-5-(1-methyl-pent-2-ynyl)-pyrimidine-2,4,6-trione ... 5-allyl-1-methyl-5-(1-methyl-2-pentynyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Hypnotics and Sedatives …
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Synonyms: … 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine ... 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine ... 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine …
Matched Description: … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl ... )-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)- …
Matched Iupac: … N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 …
Matched Description: … [L45505] CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties ... oral zavegepant in migraine prevention, and another one (NCT04987944) is evaluating the safety and efficacy ... other drugs such as [rimegepant] and [ubrogepant]. …
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Synonyms: … N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide ... N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Synonyms: … Cellulose hydroxypropyl methyl ether ... Cellulose, 2-hydroxypropyl methyl ether …
Matched Description: … binder in the process of granulation and in modified release formulations [A24840]. ... Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic ... acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and
Matched Mixtures name: … Rohto Sun and Sport …
A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Synonyms: … 1-methyl-2',6'-pipecoloxylidide ... (+-)-1-Methyl-2',6'-pipecoloxylidide ... N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide …
Matched Description: … It is indicated for infiltration, nerve block, and epidural anesthesia. ... Mepivacaine is effective topically only in large doses and therefore should not be used by this route …
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin …
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Synonyms: … methyl glycol …
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Mixtures name: … Systane Day and Night Value Pack ... Systane Day and Night Value Pack ... Foster and Thrive Long Lasting Lubricant Eye Drops …
Matched Products: … Eyelash and Eyebrow Lengthener …
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Synonyms: … methyl-dihydroartemisinine ... Dihydroqinghaosu methyl ether ... Artemisininelactol methyl ether …
Matched Description: … and may be used to treat infections caused by P. falciparum and unidentified Plasmodium …
Matched Categories: … Artemisinin and derivatives ... artemether and lumefantrine ... Antiparasitic Products, Insecticides and Repellents …
Displaying drugs 26 - 50 of 15168 in total