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Displaying drugs 51 - 75 of 10290 in total
Crizanlizumab is a humanized IgG2 monoclonal antibody used to reduce the frequency of vaso-occlusive crises in patients with sickle cell disease. Sickle cell disease is a genetically inherited condition prevalent in the Middle East, Africa, and certain parts of India. The genetic mutation associated with this disease leads to the...
Approved
Investigational
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Approved
Matched Description: … It is an inhibitor of cyclooxygenase. …
Matched Categories: … Antirheumatic Agents ... Agents causing hyperkalemia ... Nephrotoxic agents ... Anti-Inflammatory Agents ... Sensory System Agents
Molybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. Molybdenum is commonly used in metallurgy and other chemical applications however it has essential biological roles in...
Approved
Matched Description: … It is an essential trace dietary element and acts as a critical cofactor in several molybdenum-dependent …
Doxacurium chloride is a long-acting, nondepolarizing skeletal muscle relaxant for intravenous administration.
Approved
Matched Categories: … Anticholinergic Agents ... Neuromuscular Agents ... Neuromuscular Blocking Agents ... Peripheral Nervous System Agents ... Muscle Relaxants, Peripherally Acting Agents
An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Matched Description: … It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for ... An organic amine proton acceptor. ... cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an
Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Description: … The latter is an iron carbohydrate oligosaccharide that works to release iron. ... Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. …
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab was originated as an improved form of hBS23 and it was approved on November 16, 2017. ... allows it to overcome immunogenicity and unstable hemostatic efficacy produced by previous Factor VII agents
Matched Categories: … Antihemorrhagic Agents, Miscellaneous …
Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … used neuromuscular blocking agents in intensive care. ... [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly ... [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times …
Matched Categories: … Anticholinergic Agents ... Neuromuscular Agents ... Neuromuscular Blocking Agents ... Peripheral Nervous System Agents ... Muscle Relaxants, Peripherally Acting Agents
An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Description: … An alkylating agent proposed as an antineoplastic. …
Matched Categories: … Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic Agents, Alkylating ... Antineoplastic and Immunomodulating Agents
Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2...
Approved
Investigational
Matched Description: … Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited ... treatment options involving cytotoxic chemotherapy agents. ... [A193653] In November 2021 and July 20 2023, sacituzumab govitecan was also approved by the European …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild ... It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors …
Matched Categories: … Hypotensive Agents ... Cardiovascular Agents ... Antihypertensive Agents ... Agents producing tachycardia ... Agents that produce hypertension …
Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial hypercholesterolemia (HoFH) patients. It is marketed under the name Juxtapid (R).
Approved
Investigational
Matched Categories: … Hepatotoxic Agents ... Hypolipidemic Agents ... Lipid Modifying Agents ... Lipid Modifying Agents, Plain ... Hypolipidemic Agents Indicated for Hyperlipidemia …
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Categories: … Antirheumatic Agents ... Anti-Inflammatory Agents ... Agents reducing cytokine levels ... Immunosuppressive Agents ... Disease-modifying Antirheumatic Agents
Matched Products: … Truemed Group LLC …
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … It was initially approved by the FDA in 1990. ... Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. …
Matched Categories: … Antifungal Agents ... Anti-Infective Agents ... Agents causing hyperkalemia ... QTc Prolonging Agents ... Potential QTc-Prolonging Agents
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Description: … It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Mixtures name: … Truemed Group LLC …
Matched Categories: … Antidepressive Agents ... Adrenergic Agents ... Serotonin Agents ... Cardiovascular Agents ... Uterotonic agents
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Categories: … Nephrotoxic agents ... Antirheumatic Agents ... Agents causing hyperkalemia ... Anti-Inflammatory Agents ... Sensory System Agents
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Description: … Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed …
Matched Categories: … Antineoplastic Agents ... Hypotensive Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … [A245154] Notably, none of these agents are approved for use in the treatment of CAD. ... ], as well as targeting of the complement system with drugs like [eculizumab], an anti-C5 mAb, and [pegcetacoplan ... [A245159] Pharmacologic strategies have included the targeting of B-cells with agents like [rituximab …
Matched Categories: … Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents
Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Description: … prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Categories: … Heparin Group ... Hematologic Agents ... Cardiovascular Agents ... Agents causing hyperkalemia ... Fibrin Modulating Agents
Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine...
Approved
Matched Description: … Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors ... accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic use has not been approved
Matched Categories: … Autonomic Agents ... Anticholinergic Agents ... Peripheral Nervous System Agents
Quinupramine has been approved in France under the brand name Kinupril, as an antidepressant .
Approved
Matched Description: … Quinupramine has been approved in France under the brand name Kinupril, as an antidepressant [A175003 …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tricyclic ... Neurotoxic agents ... Agents that produce hypertension ... Agents that reduce seizure threshold …
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Categories: … Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Agents that reduce seizure threshold ... Antineoplastic Agents, Alkylating …
Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Description: … Celiprolol is not approved for use by the FDA in the treatment of vascular Ehlers–Danlos syndrome. …
Matched Categories: … Adrenergic Agents ... Autonomic Agents ... Antiarrhythmic agents ... Vasodilating Agents ... Cardiovascular Agents
Displaying drugs 51 - 75 of 10290 in total