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Displaying drugs 101 - 125 of 15144 in total
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid …
Matched Iupac: … 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1lambda6,2-benzothiazine-3-carboxamide …
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Menopur Powder for Injection and Solvent 75 IU ... Menopur Powder and Solvent For Solution for Injection 75iu ... MENOPUR multidose 600IU Powder and Solvent for Solution for Injection …
Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and
Matched Mixtures name: … Clease and Treat …
Matched Products: … Head and Shoulders Itch ... Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff ... Head and Shoulders Clinical Strength …
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and
Matched Mixtures name: … Honey Lemon Throat Drops ... Angidol Honey Lemon Flavor ... Honey Lemon Sore Throat Lozenges …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Chloraseptic Warming Honey Lemon ... Sting and Bite ... Bite and Sting relief …
Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
Approved
Investigational
Matched Synonyms: … 3,5-dihydroxy-α-(((p-hydroxy-α-methylphenethyl)amino)methyl)benzyl alcohol ... 5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol …
Matched Description: … Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic. …
Matched Categories: … fenoterol and ipratropium bromide ... Genito Urinary System and Sex Hormones …
Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and ... secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Synonyms: … 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol …
Matched Categories: … Adrenergic and Dopaminergic Agents …
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Mixtures name: … Pernox Crm Lemon ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit …
Matched Categories: … Salicylic Acid and Derivatives ... sodium salicylate and methenamine ... Genito Urinary System and Sex Hormones …
Matched Products: … Anti Hair Loss Gel with Arnica, Rosemary, and Lemon Extracts. ... C and C by Clean and Clear spot on spot treatment ... Proactiv Cover and Heal Duo Concealer Tan and Dark …
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with …
Matched Description: … skin discoloration, and fear and anxiety in the pediatric population. ... pediatric molluscum contagiosum, and it is the first drug to be approved for this condition. ... molluscum contagiosum, a viral cutaneous infection mainly affecting children, sexually active adults, and
Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss. However, following multiple concerns about the cardiovascular side-effects of the drug, such approval was withdrawn.
Approved
Illicit
Investigational
Withdrawn
Matched Synonyms: … d-N-ethyl-α-methyl-m-trifluoromethylphenethylamine …
Matched Categories: … Alimentary Tract and Metabolism …
In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Approved
Withdrawn
Matched Synonyms: … (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol …
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Synonyms: … 16alpha-Methyl-9alpha-fluoroprednisolone 21-acetate …
Matched Description: … one-third in patients on oxygen therapy and mechanical ventilation, respectively. ... previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and ... [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues …
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino ... 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene …
Matched Iupac: … (2S,3S)-3-[(2Z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Synonyms: … 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro ... -4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide ... 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro …
Matched Iupac: … 4-yl)methyl]amino}benzenesulfonyl)-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide ... 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- …
Matched Description: … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows …
Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Synonyms: … N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine …
Matched Iupac: … 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline …
Matched Description: … and reducing cough. ... prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs. ... It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many …
Matched Categories: … Cough and Cold Preparations …
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … Methyl benzylidene camphor …
Matched Description: … Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and
Matched Mixtures name: … Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen ... mesoestetic moisturizing sun protection BROAD SPECTRUM FOR NORMAL AND DRY SKINS …
Enasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with specific mutations in the isocitrate dehydrogenase 2 (IDH2) gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345]. Patients eligible for this treatment...
Approved
Investigational
Matched Synonyms: … 2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin …
Matched Iupac: … 2-methyl-1-({4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin …
Matched Description: … Food and Drug Administration on August 1, 2017. ... First developed by Agios Pharmaceuticals and licensed to Celgene, enasidenib was approved by U.S. ... This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Approved
Experimental
Matched Mixtures name: … CVS Medicated Chest Rub Lemon Scent ... Major Camphor and Phenol ... Up and Up Pain …
Matched Products: … Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers ... Weeks and Leo Medicated Vaporizing Steam …
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Description: … In vitro, the levo-isomer has been shown to be rapidly converted to the biologically available methyl-tetrahydrofolate ... Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives …
Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Synonyms: … 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate …
Matched Description: … It may also be used to prevent nausea, vomiting, and motion sickness. …
Matched Mixtures name: … Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... homatropine methylbromide and psycholeptics …
Displaying drugs 101 - 125 of 15144 in total