Displaying drugs 1651 - 1675 of 1863 in total
Saprisartan
Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
MM-111
MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Briciclib
Briciclib has been used in trials studying the treatment of Lymphoma, Neoplasms, Advanced Solid Tumor, and Acute Lymphocytic Leukemia.
Investigational
Matched Description: … Briciclib has been used in trials studying the treatment of Lymphoma, Neoplasms, Advanced Solid Tumor, and …
Matched Salts name: … Briciclib Sodium …
Matched Salts name: … Briciclib Sodium …
Faropenem
Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
Investigational
Matched Description: … Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and …
Matched Salts name: … Faropenem Sodium …
Matched Salts name: … Faropenem Sodium …
BQ-123
BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
Investigational
Matched Description: … Bypass Grafting, and ST-Elevation Myocardial Infarction. ... BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary …
Matched Salts name: … Bq 123 Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Salts name: … Bq 123 Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Azosemide
Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.
Investigational
Matched Description: … Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. …
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors …
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors …
Potassium bitartrate
Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Matched Description: … Potassium bitartrate has a long history of medical use as a laxative administered as a rectal suppository and …
Tiratricol
A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.
Investigational
Matched Description: … A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and …
Matched Salts name: … Tiratricol sodium …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Salts name: … Tiratricol sodium …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Talaporfin
Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Investigational
Matched Iupac: … (2S)-2-{2-[(4S,5S)-20-carboxy-4-(2-carboxyethyl)-10-ethenyl-15-ethyl-5,9,14,19-tetramethyl-21,22,23,24 …
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
Matched Salts name: … Talaporfin Sodium …
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
Matched Salts name: … Talaporfin Sodium …
Astodrimer
Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
Investigational
Matched Description: … Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. …
Matched Salts name: … Astodrimer Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Salts name: … Astodrimer Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rigosertib
Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Investigational
Matched Description: … , and Neoplasms, among others. ... Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma …
Matched Salts name: … Rigosertib Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Salts name: … Rigosertib Sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rivipansel
Rivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal impairment, Anemia, Sickle Cell, Sickle Cell Disease, and Sickle Cell Disorders, among others.
Investigational
Matched Description: … impairment, Anemia, Sickle Cell, Sickle Cell Disease, and Sickle Cell Disorders, among others. ... Rivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal …
Matched Salts name: … Rivipansel sodium …
Matched Salts name: … Rivipansel sodium …
Bazlitoran
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Salts name: … Bazlitoran sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Salts name: … Bazlitoran sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Reltecimod
Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Investigational
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Salts name: … Reltecimod sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Matched Salts name: … Reltecimod sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Lexanersen
Lexanersen is an antisense oligonucleotide under investigation for use as a disease-modifying therapy in Huntington's disease.
Investigational
Matched Salts name: … Lexanersen sodium …
Ecabet
Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss...
Investigational
Matched Description: … by conjunctival goblet cells and corneal epithelia. ... Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced ... Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis. …
Matched Salts name: … Ecabet sodium …
Matched Salts name: … Ecabet sodium …
Diquafosol
Experimental
Matched Categories: … Phosphate salts ... Nucleic Acids, Nucleotides, and Nucleosides …
Anbenitamab
Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …
CY-1503
CY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium salt, two beta-D-galactopyranosyl residues, one 2-acetamido-beta-Dglucopyranosyl unit, and one alpha-L-fucopyranosyl unit. It was investigated in cardiopulmonary bypass during surgical repair of congenital heart lesions.
Investigational
Matched Description: … CY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium ... salt, two beta-D-galactopyranosyl residues, one 2-acetamido-beta-Dglucopyranosyl unit, and one alpha-L-fucopyranosyl …
SPL84-23-1
SPL84-23-1 is a sodium salt of 19-bp single-stranded RNA uniformly modified 2'-O-(2-methoxyethyl) phosphorothioate Antisense Oligonucleotide (ASO) consisting of 19 nucleotide residues with the sequence 5'-5MeC-5MeU-G-5MeC-A-A-5MeC-A-G-A-5MeU-G-G-A-A-G-A-5MeC-5MeU-3'
Investigational
Matched Description: … SPL84-23-1 is a sodium salt of 19-bp single-stranded RNA uniformly modified 2'-O-(2-methoxyethyl) phosphorothioate …
AMG 424
AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …
L-alpha-Glycerophosphorylethanolamine
Experimental
Matched Synonyms: … Ethanolamine glycerophosphate anhydrous …
Displaying drugs 1651 - 1675 of 1863 in total