Seizures and epilepsy: an overview for neuroscientists.

Article Details

Citation

Stafstrom CE, Carmant L

Seizures and epilepsy: an overview for neuroscientists.

Cold Spring Harb Perspect Med. 2015 Jun 1;5(6):a022426. doi: 10.1101/cshperspect.a022426.

PubMed ID
26033084 [ View in PubMed
]
Abstract

Epilepsy is one of the most common and disabling neurologic conditions, yet we have an incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for much of epilepsy. This article reviews the clinical aspects of seizures and epilepsy with the goal of providing neuroscientists an introduction to aspects that might be amenable to scientific investigation. Seizures and epilepsy are defined, diagnostic methods are reviewed, various clinical syndromes are discussed, and aspects of differential diagnosis, treatment, and prognosis are considered to enable neuroscientists to formulate basic and translational research questions.

DrugBank Data that Cites this Article

Drugs
Drug Interactions
DrugsInteraction
1,2-Benzodiazepine
Clobazam
The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with 1,2-Benzodiazepine.
1,2-Benzodiazepine
Midazolam
The risk or severity of sedation and CNS depression can be increased when Midazolam is combined with 1,2-Benzodiazepine.
Acetazolamide
Clobazam
The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Acetazolamide.
Acetophenazine
Clobazam
The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Acetophenazine.
Acetophenazine
Midazolam
The risk or severity of sedation and CNS depression can be increased when Midazolam is combined with Acetophenazine.