Hypokalemia: a clinical update.

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Kardalas E, Paschou SA, Anagnostis P, Muscogiuri G, Siasos G, Vryonidou A

Hypokalemia: a clinical update.

Endocr Connect. 2018 Apr;7(4):R135-R146. doi: 10.1530/EC-18-0109. Epub 2018 Mar 14.

PubMed ID

29540487 [ View in PubMed

]

Abstract

Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1) the definition and prevalence of hypokalemia, (2) the physiology of potassium homeostasis, (3) the various causes leading to hypokalemia, (4) the diagnostic steps for the assessment of hypokalemia and (5) the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.

DrugBank Data that Cites this Article

Drugs

Potassium

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Potassium	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Unknown	Regulator	Details

Drug Transporters

Drug	Transporter	Kind	Organism	Pharmacological Action	Actions
Potassium	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Unknown	Substrate	Details

Drug Interactions

Drugs	Interaction
Integrate drug-drug interactions in your software
Olodaterol Caffeine	Caffeine may increase the hyperkalemic activities of Olodaterol.
Olodaterol Theophylline	Theophylline may increase the hyperkalemic activities of Olodaterol.
Olodaterol Dyphylline	Dyphylline may increase the hyperkalemic activities of Olodaterol.
Olodaterol Pentoxifylline	Pentoxifylline may increase the hyperkalemic activities of Olodaterol.
Olodaterol Mercaptopurine	Mercaptopurine may increase the hyperkalemic activities of Olodaterol.