Identification of G protein-coupled receptor genes from the human genome sequence.
Article Details
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Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S
Identification of G protein-coupled receptor genes from the human genome sequence.
FEBS Lett. 2002 Jun 5;520(1-3):97-101.
- PubMed ID
- 12044878 [ View in PubMed]
- Abstract
We have identified novel G protein-coupled receptors (GPCRs) with no introns in the coding region from the human genome sequence: 322 olfactory receptors; 22 taste receptors; 128 registered GPCRs for endogenous ligands; 50 novel GPCR candidates homologous to registered GPCRs for endogenous ligands; and 59 novel GPCR candidates not homologous to registered GPCRs. The total number of GPCRs with and without introns in the human genome was estimated to be approximately 950, of which 500 are odorant or taste receptors and 450 are receptors for endogenous ligands.
DrugBank Data that Cites this Article
- Polypeptides
Name UniProt ID Cysteinyl leukotriene receptor 2 Q9NS75 Details P2Y purinoceptor 12 Q9H244 Details Hydroxycarboxylic acid receptor 2 Q8TDS4 Details Sphingosine 1-phosphate receptor 5 Q9H228 Details Glucose-dependent insulinotropic receptor Q8TDV5 Details Leukotriene B4 receptor 2 Q9NPC1 Details G-protein coupled bile acid receptor 1 Q8TDU6 Details P2Y purinoceptor 13 Q9BPV8 Details