Membrane-associated progesterone receptor component 1

Details

Name
Membrane-associated progesterone receptor component 1
Synonyms
  • HPR6.6
  • mPR
  • PGRMC
Gene Name
PGRMC1
Organism
Humans
Amino acid sequence
>lcl|BSEQ0008675|Membrane-associated progesterone receptor component 1
MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDD
EPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRD
ASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVY
SDEEEPKDESARKND
Number of residues
195
Molecular Weight
21670.9
Theoretical pI
Not Available
GO Classification
Functions
heme binding / steroid binding
Processes
axon guidance
Components
endoplasmic reticulum / endoplasmic reticulum membrane / extracellular exosome / integral component of membrane / membrane / nucleolus
General Function
Steroid binding
Specific Function
Receptor for progesterone.
Pfam Domain Function
Transmembrane Regions
25-43
Cellular Location
Microsome membrane
Gene sequence
>lcl|BSEQ0020809|Membrane-associated progesterone receptor component 1 (PGRMC1)
ATGGCTGCCGAGGATGTGGTGGCGACTGGCGCCGACCCAAGCGATCTGGAGAGCGGCGGG
CTGCTGCATGAGATTTTCACGTCGCCGCTCAACCTGCTGCTGCTTGGCCTCTGCATCTTC
CTGCTCTACAAGATCGTGCGCGGGGACCAGCCGGCGGCCAGCGGCGACAGCGACGACGAC
GAGCCGCCCCCTCTGCCCCGCCTCAAGCGGCGCGACTTCACCCCCGCCGAGCTGCGGCGC
TTCGACGGCGTCCAGGACCCGCGCATACTCATGGCCATCAACGGCAAGGTGTTCGATGTG
ACCAAAGGCCGCAAATTCTACGGGCCCGTCAAGTATCATCACGTGGGCAAACTGCTGAAG
GAGGGGGAGGAGCCCACTGTGTACTCAGATGAGGAAGAACCAAAAGATGAGAGTGCCCGG
AAAAATGATTAA
Chromosome Location
X
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDO00264
UniProtKB Entry NamePGRC1_HUMAN
HGNC IDHGNC:16090
General References
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00514DextromethorphanapprovedunknownbinderDetails
DB00540NortriptylineapprovedunknownbinderDetails
DB01104SertralineapprovedunknowninhibitorbinderDetails