Antitrematodals

Name
Antitrematodals
Accession Number
DBCAT002496
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
PraziquantelAn anthelmintic medication used to treat parasitic worm infections such as schistosomiasis, clonorchiasis, and opisthorchiasis
OxamniquineFor treatment of Schistosomiasis caused by Schistosoma mansoni
BithionolBithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the...
MetrifonateMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
StibophenStibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms.
NiridazoleNot Annotated
Drugs & Drug Targets
DrugTargetType
PraziquantelSchistosome calcium ion (Ca2+) channelstarget
PraziquantelCytochrome P450 3A4enzyme
PraziquantelCytochrome P450 1A2enzyme
PraziquantelCytochrome P450 2C19enzyme
PraziquantelCytochrome P450 3A5enzyme
PraziquantelSerum albumincarrier
OxamniquineDNAtarget
OxamniquineCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 2C9enzyme
TriclabendazoleExcretory Secretory (ES) proteinstarget
TriclabendazoleCytochrome P450 3A4enzyme
TriclabendazoleCytochrome P450 1A1enzyme
TriclabendazoleCytochrome P450 1B1enzyme
TriclabendazoleCytochrome P450 2C19enzyme
TriclabendazoleCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 2A6enzyme
TriclabendazoleCytochrome P450 2C8enzyme
TriclabendazoleCytochrome P450 2B6enzyme