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Identification
NamePantoprazole
Accession NumberDB00213  (APRD00073)
TypeSmall Molecule
GroupsApproved
Description

Pantoprazole is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

Structure
Thumb
Synonyms
Pantoprazol
Pantoprazolum
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Abbott-pantoprazoletablet (delayed-release)40 mgoralAbbott Laboratories, Limited2014-03-17Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Abbott-pantoprazoletablet (delayed-release)20 mgoralAbbott Laboratories, LimitedNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Act Pantoprazoletablet (delayed-release)40 mgoralActavis Pharma Company2008-06-04Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Auro-pantoprazoletablet (delayed-release)40 mgoralAuro Pharma IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ava-pantoprazoletablet (delayed-release)40 mgoralAvanstra Inc2011-09-192014-08-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ava-pantoprazoletablet (delayed-release)20 mgoralAvanstra Inc2011-09-192014-08-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dom-pantoprazoletablet (delayed-release)20 mgoralDominion PharmacalNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dom-pantoprazoletablet (delayed-release)40 mgoralDominion Pharmacal2012-10-25Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dom-pantoprazolepowder for solution40 mgintravenousDominion PharmacalNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ipg-pantoprazoletablet (delayed-release)20 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ipg-pantoprazoletablet (delayed-release)40 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Jamp-pantoprazoletablet (delayed-release)20 mgoralJamp Pharma Corporation2014-02-11Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Jamp-pantoprazoletablet (delayed-release)40 mgoralJamp Pharma Corporation2014-12-12Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mar-pantoprazoletablet (delayed-release)40 mgoralMarcan Pharmaceuticals Inc2014-07-18Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mar-pantoprazoletablet (delayed-release)20 mgoralMarcan Pharmaceuticals IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mint-pantoprazoletablet (delayed-release)20 mgoralMint Pharmaceuticals IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mint-pantoprazoletablet (delayed-release)40 mgoralMint Pharmaceuticals Inc2014-01-16Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mylan-pantoprazoletablet (delayed-release)40 mgoralMylan Pharmaceuticals Ulc2008-06-03Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mylan-pantoprazole Ttablet (delayed-release)40 mgoralMylan Pharmaceuticals Ulc2015-08-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ntp-pantoprazoletablet (delayed-release)40 mgoralNt Pharma Canada LtdNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ntp-pantoprazoletablet (delayed-release)20 mgoralNt Pharma Canada LtdNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Panto IVpowder for solution40 mgintravenousTakeda Canada Inc1999-04-06Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Panto-byktablet (enteric-coated)20 mgoralNycomed GmbhNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Panto-byktablet (enteric-coated)40 mgoralNycomed GmbhNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoloctablet (enteric-coated)20 mgoralTakeda Canada Inc2000-05-02Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoloctablet (enteric-coated)40 mgoralTakeda Canada Inc1997-03-05Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)20 mgoralMeliapharm Inc2009-08-282014-06-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralPharmascience Inc2015-05-20Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)20 mgoralLaboratoire Riva IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralLaboratoire Riva Inc2014-10-16Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralSivem Pharmaceuticals Ulc2012-06-10Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)20 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)20 mgoralSivem Pharmaceuticals Ulc2012-06-10Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralSanis Health Inc2011-09-13Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralSorres Pharma Inc2009-02-262014-06-20Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralPro Doc Limitee2009-01-29Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralDominion Pharmacal2015-10-30Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet (delayed-release)40 mgoralMeliapharm Inc2009-08-282014-06-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole for Injectionpowder for solution40 mgintravenousTeva Canada Limited2010-05-17Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole for Injectionpowder for solution40 mgintravenousFresenius Kabi Canada Ltd2010-12-14Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole Magnesiumtablet (enteric-coated)40 mgoralAspri Pharma Canada Inc2015-11-25Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole Sodium Delayed Releasetablet, delayed release20 mg/1oralSTAT Rx USA LLC2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release20 mg/1oralWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release40 mg/1oralCardinal Health2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release40 mg/1oralPreferred Pharmaceuticals, Inc.2014-02-06Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release40 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release40 mg/1oralContract Pharmacy Services Pa2010-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release40 mg/1oralCardinal Health2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release20 mg/1oralProficient Rx2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release20 mg/1oralLake Erie Medical DBA Quality Care Products LLC2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-releasetablet, delayed release40 mg/1oralWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed-release Delayed-releasetablet, delayed release40 mg/1oralSt Marys Medical Park Pharmacy2014-05-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium for Injectionpowder for solution40 mgintravenousGeneric Medical Partners IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole Sodium for Injectionpowder for solution40 mgintravenousMylan Pharmaceuticals UlcNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole Sodium for Injectionpowder for solution40 mgintravenousSandoz Canada Incorporated2008-03-11Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole Sodiumdelayed-release Delayed-releasetablet, delayed release40 mg/1oralPd Rx Pharmaceuticals, Inc.2008-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole-20tablet (delayed-release)20 mgoralSivem Pharmaceuticals Ulc2014-07-21Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazole-40tablet (delayed-release)40 mgoralSivem Pharmaceuticals Ulc2014-07-21Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
PHL-pantoprazolepowder for solution40 mgintravenousPharmel IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
PMS-pantoprazoletablet (delayed-release)40 mgoralPharmascience Inc2008-06-04Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
PMS-pantoprazoletablet (delayed-release)20 mgoralPharmascience Inc2008-06-04Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
PMS-pantoprazolepowder for solution40 mgintravenousPharmascience Inc2007-04-03Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Priva-pantoprazoletablet (delayed-release)40 mgoralPharmapar Inc2015-01-13Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Protonixtablet, delayed release40 mg/1oralRebel Distributors Corp2001-08-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release20 mg/1oralPhysicians Total Care, Inc.2003-05-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release40 mg/1oralAvera Mc Kennan Hospital2015-09-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release40 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasegranule, delayed release40 mg/1oralCardinal Health2008-02-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasegranule, delayed release40 mg/1oralWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2008-02-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release20 mg/1oralCardinal Health2000-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release20 mg/1oralWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2000-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release20 mg/1oralSTAT Rx USA LLC2000-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release40 mg/1oralWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2000-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release40 mg/1oralPhysicians Total Care, Inc.2001-08-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release40 mg/1oralCardinal Health2000-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix Delayed-releasetablet, delayed release20 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix I.V.injection, powder, for solution40 mg/10mLintravenousCardinal Health2001-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix I.V.injection, powder, for solution40 mg/10mLintravenousWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2014-03-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix I.V.injection, powder, for solution40 mg/10mLintravenousWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2001-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix I.V.injection, powder, for solution40 mg/10mLintravenousWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2001-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix I.V.injection, powder, for solution40 mg/10mLintravenousCardinal Health2001-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix I.V.injection, powder, for solution40 mg/10mLintravenousCardinal Health2001-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Protonix I.V.injection, powder, for solution40 mg/10mLintravenousWyeth Pharmaceuticals Inc., a subsidiary of Pfizer Inc.2013-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Q-pantoprazoletablet (delayed-release)40 mgoralQd Pharmaceuticals Ulc2011-10-032015-08-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ran-pantoprazoletablet (delayed-release)40 mgoralRanbaxy Pharmaceuticals Canada Inc.2008-02-12Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ran-pantoprazoletablet (delayed-release)20 mgoralRanbaxy Pharmaceuticals Canada Inc.2008-02-12Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ratio-pantoprazoletablet (delayed-release)40 mgoralRatiopharm Inc Division Of Teva Canada Limited2008-06-032015-10-26Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ratio-pantoprazoletablet (delayed-release)20 mgoralRatiopharm Inc Division Of Teva Canada Limited2008-06-032015-10-26Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Riva-pantoprazoletablet (delayed-release)20 mgoralLaboratoire Riva IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Riva-pantoprazoletablet (delayed-release)40 mgoralLaboratoire Riva Inc2008-10-27Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Sandoz Pantoprazoletablet (delayed-release)20 mgoralSandoz Canada Incorporated2008-06-03Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Sandoz Pantoprazoletablet (delayed-release)40 mgoralSandoz Canada Incorporated2008-06-03Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tectatablet (enteric-coated)40 mgoralTakeda Canada Inc2006-03-15Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Teva-pantoprazoletablet (delayed-release)40 mgoralTeva Canada Limited2008-04-11Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Teva-pantoprazoletablet (delayed-release)20 mgoralTeva Canada Limited2008-04-11Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Teva-pantoprazole Magnesiumtablet (delayed-release)40 mgoralTeva Canada Limited2015-11-16Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Torrent-pantoprazoletablet (delayed-release)40 mgoralTorrent Pharmaceuticals LimitedNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Torrent-pantoprazoletablet (delayed-release)20 mgoralTorrent Pharmaceuticals LimitedNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Van-pantoprazoletablet (delayed-release)40 mgoralVanc Pharmaceuticals IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo-pantoprazoletablet (delayed-release)40 mgoralApotex Inc2008-03-05Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Apo-pantoprazoletablet (delayed-release)20 mgoralApotex Inc2008-03-05Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pantoprazoletablet, delayed release40 mg/1oralState of Florida DOH Central Pharmacy2014-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazoletablet, delayed release40 mg/1oralDr.Reddy's Laboratories Limited2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazoletablet, delayed release40 mg/1oralMajor Pharmaceuticals2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazoletablet, delayed release20 mg/1oralDr.Reddy's Laboratories Limited2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazoletablet, delayed release20 mg/1oralState of Florida DOH Central Pharmacy2014-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazoletablet, delayed release40 mg/1oralLegacy Pharmaceutical Packaging2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazoletablet, delayed release40 mg/1oralCardinal Health2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralAv Pak2013-01-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralClinical Solutions Wholesale, Llc2007-12-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralSun Pharmaceutical Industries Limited2014-12-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralAmerican Health Packaging2012-03-012016-01-01Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralAmerican Health Packaging2013-08-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralTeva Pharmaceuticals USA Inc2007-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralREMEDYREPACK INC.2015-01-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralbryant ranch prepack2007-12-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralLegacy Pharmaceutical Packaging, Llc2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralMedsource Pharmaceuticals2007-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralMajor Pharmaceuticals2015-06-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralAurobindo Pharma Limited2012-09-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPreferred Pharmaceuticals, Inc.2013-08-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet40 mg/1oralREMEDYREPACK INC.2011-11-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralMacleods Pharmaceuticals Limited2011-12-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralKremers Urban Pharmaceuticals Inc.2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralWockhardt Limited2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralRanbaxy Pharmaceuticals Inc.2012-05-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralLegacy Pharmaceutical Packaging, Llc2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralAphena Pharma Solutions Tennessee, Inc.2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralREMEDYREPACK INC.2014-12-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralAurobindo Pharma Limited2012-09-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPreferred Pharmaceuticals, Inc.2013-11-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralREMEDYREPACK INC.2011-11-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralCamber Pharmaceuticals, Inc.2014-09-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralREMEDYREPACK INC.2014-06-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralDIRECT RX2015-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralWockhardt Limited2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralRanbaxy Pharmaceuticals Inc.2012-05-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralLegacy Pharmaceutical Packaging, Llc2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralPd Rx Pharmaceuticals, Inc.2015-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2007-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralMylan Institutional Inc.2011-02-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralSt Marys Medical Park Pharmacy2013-08-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPhysicians Total Care, Inc.2009-06-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralWockhardt USA LLC.2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPreferred Pharmaceuticals, Inc.2014-03-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralSafecor Health, LLC2014-09-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralCamber Pharmaceuticals, Inc.2014-09-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralREMEDYREPACK INC.2014-04-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralCardinal Health2012-01-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralProficient Rx LP2007-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralCardinal Health2015-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralLegacy Pharmaceutical Packaging2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralRebel Distributors Corp2007-09-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2012-01-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralUnit Dose Services2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralJubilant Cadista Pharmaceuticals Inc.2011-09-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralPhysicians Total Care, Inc.2008-01-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPreferred Pharmaceuticals, Inc.2014-02-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralSun Pharma Global FZE2007-09-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralRebel Distributors Corp2010-10-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralREMEDYREPACK INC.2014-02-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralCardinal Health2012-09-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralWockhardt USA LLC.2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralLake Erie Medical DBA Quality Care Products LLC2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralLegacy Pharmaceutical Packaging2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralOrchid Pharma Inc2015-03-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralMylan Pharmaceuticals Inc.2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralUnit Dose Services2007-09-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralJubilant Cadista Pharmaceuticals Inc.2011-09-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralProficient Rx LP2007-12-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralSun Pharma Global FZE2007-09-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiuminjection, powder, for solution40 mg/1intravenousAkorn, Inc.2012-11-082016-02-05Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralREMEDYREPACK INC.2014-02-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralREMEDYREPACK INC.2015-10-09Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralCardinal Health2013-01-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralReady Meds2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPreferred Pharmaceuticals, Inc.2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralOrchid Pharma Inc2015-03-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralMylan Pharmaceuticals Inc.2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralAv Pak2015-01-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralState of Florida DOH Central Pharmacy2014-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralProficient Rx LP2011-02-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralREMEDYREPACK INC.2013-05-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralREMEDYREPACK INC.2015-09-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPreferred Pharmaceuticals, Inc.2014-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralActavis Inc.2011-02-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralTorrent Pharmaceuticals Limited2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralKremers Urban Pharmaceuticals Inc.2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralLake Erie Medical DBA Quality Care Products LLC2007-09-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralPrasco Laboratories2015-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralAmerican Health Packaging2013-05-152015-12-29Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralREMEDYREPACK INC.2013-02-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralRx Change Co.2007-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralAv Pak2013-01-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralClinical Solutions Wholesale2011-02-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralSun Pharmaceutical Industries Limited2014-12-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralAmerican Health Packaging2014-12-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralLake Erie Medical DBA Quality Care Products LLC2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralTeva Pharmaceuticals USA Inc2007-12-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralREMEDYREPACK INC.2015-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralCardinal Health2011-02-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralbryant ranch prepack2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralPreferred Pharmaceuticals, Inc.2014-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralActavis Inc.2011-02-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralTorrent Pharmaceuticals Limited2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralREMEDYREPACK INC.2013-05-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralKremers Urban Pharmaceuticals Inc.2011-01-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralLake Erie Medical DBA Quality Care Products LLC2013-04-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralPrasco Laboratories2015-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralAmerican Health Packaging2013-05-152015-12-29Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralREMEDYREPACK INC.2011-12-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release40 mg/1oralMacleods Pharmaceuticals Limited2011-12-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodiumtablet, delayed release20 mg/1oralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed Releasetablet, delayed release40 mg/1oralNorthwind Pharmaceuticals2014-03-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Delayed Releasetablet40 mg/1oralNew Horizon Rx Group, LLC2013-08-25Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Drtablet, delayed release40 mg/1oralLake Erie Medical DBA Quality Care Products LLC2011-01-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pantoprazole Sodium Drtablet, delayed release40 mg/1oralNorthwind Pharmaceuticals, LLC2014-07-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Over the Counter ProductsNot Available
International Brands
NameCompany
PantozolNot Available
Brand mixturesNot Available
Salts
Name/CASStructureProperties
Pantoprazole Magnesium
ThumbNot applicableDBSALT000853
Pantoprazole Sodium
138786-67-1
Thumb
  • InChI Key: YNWDKZIIWCEDEE-UHFFFAOYNA-N
  • Monoisotopic Mass: 405.057077726
  • Average Mass: 405.352
DBSALT000386
Categories
UNIID8TST4O562
CAS number102625-70-7
WeightAverage: 383.37
Monoisotopic: 383.075133083
Chemical FormulaC16H15F2N3O4S
InChI KeyInChIKey=IQPSEEYGBUAQFF-UHFFFAOYSA-N
InChI
InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)
IUPAC Name
6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole
SMILES
COC1=C(OC)C(CS(=O)C2=NC3=C(N2)C=C(OC(F)F)C=C3)=NC=C1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as sulfinylbenzimidazoles. These are polycyclic aromatic compounds containing a sulfinyl group attached at the position 2 of a benzimidazole moiety.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassBenzimidazoles
Sub ClassSulfinylbenzimidazoles
Direct ParentSulfinylbenzimidazoles
Alternative Parents
Substituents
  • Sulfinylbenzimidazole
  • Alkyl aryl ether
  • Benzenoid
  • Pyridine
  • Heteroaromatic compound
  • Imidazole
  • Azole
  • Sulfoxide
  • Azacycle
  • Sulfinyl compound
  • Ether
  • Halomethane
  • Hydrocarbon derivative
  • Organosulfur compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organofluoride
  • Organohalogen compound
  • Alkyl halide
  • Alkyl fluoride
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External DescriptorsNot Available
Pharmacology
IndicationShort-term (up to 16 weeks) treatment of erosive esophagitis.
PharmacodynamicsPantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.
Mechanism of actionPantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H+,K+ )- ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect is dose- related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus.
AbsorptionPantoprazole is well absorbed. It undergoes little first-pass metabolism resulting in an absolute bioavailability of approximately 77%.
Volume of distribution
  • 11.0 to 23.6 L
Protein binding98%
Metabolism

Pantoprazole is extensively metabolized in the liver through the cytochrome P450 (CYP) system. The main metabolic pathway is demethylation, by CYP2C19, with subsequent sulfation; other metabolic pathways include oxidation by CYP3A4. There is no evidence that any of the pantoprazole metabolites have significant pharmacologic activity.

SubstrateEnzymesProduct
Pantoprazole
Not Available
Active Metabolite of PantoprazoleDetails
Route of eliminationAfter administration of a single intravenous dose of 14C-labeled pantoprazole to healthy, normal metabolizer subjects, approximately 71% of the dose was excreted in the urine with 18% excreted in the feces through biliary excretion.
Half life1 hour
Clearance
  • 7.6-14.0 L/h
ToxicitySingle intravenous doses of pantoprazole at 378, 230, and 266 mg/kg (38, 46, and 177 times the recommended human dose based on body surface area) were lethal to mice, rats and dogs, respectively. The symptoms of toxicity included hypoactivity, ataxia, hunched sitting, limb-splay, lateral position, segregation, absence of ear reflex, and tremor. There is limited experience regarding cases of human overdosage, and treatment should be symptomatic and supportive.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9935
Blood Brain Barrier-0.5777
Caco-2 permeable+0.7262
P-glycoprotein substrateNon-substrate0.6127
P-glycoprotein inhibitor IInhibitor0.5587
P-glycoprotein inhibitor IINon-inhibitor0.9198
Renal organic cation transporterNon-inhibitor0.6285
CYP450 2C9 substrateNon-substrate0.84
CYP450 2D6 substrateNon-substrate0.8683
CYP450 3A4 substrateSubstrate0.7254
CYP450 1A2 substrateInhibitor0.7639
CYP450 2C9 inhibitorNon-inhibitor0.8054
CYP450 2D6 inhibitorNon-inhibitor0.7308
CYP450 2C19 inhibitorInhibitor0.7877
CYP450 3A4 inhibitorNon-inhibitor0.7258
CYP450 inhibitory promiscuityHigh CYP Inhibitory Promiscuity0.903
Ames testNon AMES toxic0.5527
CarcinogenicityNon-carcinogens0.8108
BiodegradationNot ready biodegradable0.9972
Rat acute toxicity2.3466 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9228
hERG inhibition (predictor II)Non-inhibitor0.8734
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Wyeth pharmaceuticals inc
  • Kudco ireland ltd
  • Sun pharma global inc
  • Teva pharmaceuticals usa inc
Packagers
Dosage forms
FormRouteStrength
Powder for solutionintravenous40 mg
Tablet (enteric-coated)oral20 mg
Tablet (enteric-coated)oral40 mg
Injection, powder, for solutionintravenous40 mg/1
Tabletoral40 mg/1
Tablet, delayed releaseoral20 mg/1
Tablet, delayed releaseoral40 mg/1
Granule, delayed releaseoral40 mg/1
Injection, powder, for solutionintravenous40 mg/10mL
Tablet (delayed-release)oral20 mg
Tablet (delayed-release)oral40 mg
Prices
Unit descriptionCostUnit
Protonix iv 40 mg vial14.4USD vial
Protonix 40 mg tablet dr8.91USD tablet
Protonix 20 mg tablet5.43USD tab
Protonix 40 mg Enteric Coated Tabs5.43USD tab
Protonix dr 20 mg tablet5.22USD tablet
Protonix dr 40 mg tablet5.22USD tablet
Pantoprazole Sodium 20 mg Enteric Coated Tabs4.26USD tab
Pantoprazole Sodium 40 mg Enteric Coated Tabs4.26USD tab
Pantoprazole sod dr 20 mg tablet3.93USD tablet
Pantoprazole sod dr 40 mg tablet3.93USD tablet
Pantoloc 40 mg Enteric-Coated Tablet2.28USD tablet
Apo-Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Co Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Mylan-Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Novo-Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Phl-Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Pms-Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Ran-Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Ratio-Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
Sandoz Pantoprazole 40 mg Enteric-Coated Tablet1.27USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
CountryPatent NumberApprovedExpires (estimated)
Canada20926942005-04-052011-09-06
Canada23410312006-04-042019-08-12
Canada24288702006-05-232021-11-17
United States47585791993-07-192010-07-19
United States75443702006-12-072026-12-07
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting pointBecause of gradual degradation of pantoprazole sodium during heating, the melting point cannot be determined.Not Available
water solubilityFreely soluble in water.Not Available
logP0.5Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.495 mg/mLALOGPS
logP2.11ALOGPS
logP2.18ChemAxon
logS-2.9ALOGPS
pKa (Strongest Acidic)9.15ChemAxon
pKa (Strongest Basic)3.55ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area86.33 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity90.05 m3·mol-1ChemAxon
Polarizability35.17 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
References
Synthesis Reference

Rudolf Linder, “Freeze-dried pantoprazole preparation and pantoprazole injection.” U.S. Patent US20030003058, issued January 02, 2003.

US20030003058
General ReferencesNot Available
External Links
ATC CodesA02BC02
AHFS Codes
  • 56:28.36
PDB EntriesNot Available
FDA labelDownload (183 KB)
MSDSDownload (58.1 KB)
Interactions
Drug Interactions
Drug
AbirateroneThe metabolism of Pantoprazole can be decreased when combined with Abiraterone.
AlendronateThe therapeutic efficacy of Alendronate can be decreased when used in combination with Pantoprazole.
AmphetaminePantoprazole can cause an increase in the absorption of Amphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
AripiprazoleThe serum concentration of Aripiprazole can be decreased when it is combined with Pantoprazole.
ArmodafinilThe metabolism of Pantoprazole can be decreased when combined with Armodafinil.
AtazanavirThe serum concentration of Atazanavir can be decreased when it is combined with Pantoprazole.
BortezomibThe metabolism of Pantoprazole can be decreased when combined with Bortezomib.
BosutinibThe serum concentration of Bosutinib can be decreased when it is combined with Pantoprazole.
CarbamazepineThe metabolism of Pantoprazole can be increased when combined with Carbamazepine.
CefditorenThe serum concentration of Cefditoren can be decreased when it is combined with Pantoprazole.
ChloramphenicolThe metabolism of Pantoprazole can be decreased when combined with Chloramphenicol.
CimetidineThe metabolism of Pantoprazole can be decreased when combined with Cimetidine.
ClodronateThe therapeutic efficacy of Clodronate can be decreased when used in combination with Pantoprazole.
ClopidogrelThe serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Pantoprazole resulting in a loss in efficacy.
CysteamineThe therapeutic efficacy of Cysteamine can be decreased when used in combination with Pantoprazole.
Dabigatran etexilateThe serum concentration of the active metabolites of Dabigatran etexilate can be reduced when Dabigatran etexilate is used in combination with Pantoprazole resulting in a loss in efficacy.
DabrafenibThe serum concentration of Pantoprazole can be decreased when it is combined with Dabrafenib.
DasatinibThe serum concentration of Dasatinib can be decreased when it is combined with Pantoprazole.
DelavirdineThe serum concentration of Delavirdine can be decreased when it is combined with Pantoprazole.
DexmethylphenidatePantoprazole can cause an increase in the absorption of Dexmethylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
DextroamphetaminePantoprazole can cause an increase in the absorption of Dextroamphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
EfavirenzThe metabolism of Pantoprazole can be decreased when combined with Efavirenz.
ErlotinibThe serum concentration of Erlotinib can be decreased when it is combined with Pantoprazole.
Eslicarbazepine acetateThe metabolism of Pantoprazole can be decreased when combined with Eslicarbazepine acetate.
EsomeprazoleThe metabolism of Pantoprazole can be decreased when combined with Esomeprazole.
EtravirineThe metabolism of Pantoprazole can be decreased when combined with Etravirine.
FluconazoleThe serum concentration of Pantoprazole can be increased when it is combined with Fluconazole.
FluoxetineThe metabolism of Pantoprazole can be decreased when combined with Fluoxetine.
FluvoxamineThe metabolism of Pantoprazole can be decreased when combined with Fluvoxamine.
FosphenytoinThe metabolism of Pantoprazole can be increased when combined with Fosphenytoin.
GefitinibThe serum concentration of Gefitinib can be decreased when it is combined with Pantoprazole.
GemfibrozilThe metabolism of Pantoprazole can be decreased when combined with Gemfibrozil.
IbandronateThe therapeutic efficacy of Ibandronate can be decreased when used in combination with Pantoprazole.
IndinavirThe serum concentration of Indinavir can be decreased when it is combined with Pantoprazole.
Iron DextranPantoprazole can cause a decrease in the absorption of Iron Dextran resulting in a reduced serum concentration and potentially a decrease in efficacy.
IsoniazidThe metabolism of Pantoprazole can be decreased when combined with Isoniazid.
ItraconazoleThe serum concentration of Itraconazole can be decreased when it is combined with Pantoprazole.
KetoconazoleThe serum concentration of Ketoconazole can be decreased when it is combined with Pantoprazole.
LedipasvirThe serum concentration of Ledipasvir can be decreased when it is combined with Pantoprazole.
LopinavirThe metabolism of Pantoprazole can be increased when combined with Lopinavir.
LuliconazoleThe serum concentration of Pantoprazole can be increased when it is combined with Luliconazole.
LumacaftorThe serum concentration of Pantoprazole can be decreased when it is combined with Lumacaftor.
MesalazineThe therapeutic efficacy of Mesalazine can be decreased when used in combination with Pantoprazole.
MethotrexateThe serum concentration of Methotrexate can be increased when it is combined with Pantoprazole.
MethylphenidatePantoprazole can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
MoclobemideThe metabolism of Pantoprazole can be decreased when combined with Moclobemide.
ModafinilThe metabolism of Pantoprazole can be decreased when combined with Modafinil.
Mycophenolate mofetilThe serum concentration of Mycophenolate mofetil can be decreased when it is combined with Pantoprazole.
Mycophenolic acidThe serum concentration of Mycophenolic acid can be decreased when it is combined with Pantoprazole.
NelfinavirThe serum concentration of the active metabolites of Nelfinavir can be reduced when Nelfinavir is used in combination with Pantoprazole resulting in a loss in efficacy.
NicardipineThe metabolism of Pantoprazole can be decreased when combined with Nicardipine.
NilotinibThe serum concentration of Nilotinib can be decreased when it is combined with Pantoprazole.
OmeprazoleThe metabolism of Pantoprazole can be decreased when combined with Omeprazole.
PamidronateThe therapeutic efficacy of Pamidronate can be decreased when used in combination with Pantoprazole.
PazopanibThe serum concentration of Pazopanib can be increased when it is combined with Pantoprazole.
PhenytoinThe metabolism of Pantoprazole can be increased when combined with Phenytoin.
PosaconazoleThe serum concentration of Posaconazole can be decreased when it is combined with Pantoprazole.
RaltegravirThe serum concentration of Raltegravir can be increased when it is combined with Pantoprazole.
RifampicinThe metabolism of Pantoprazole can be increased when combined with Rifampicin.
RilpivirineThe serum concentration of Rilpivirine can be decreased when it is combined with Pantoprazole.
RiociguatThe serum concentration of Riociguat can be decreased when it is combined with Pantoprazole.
RisedronateThe therapeutic efficacy of Risedronate can be decreased when used in combination with Pantoprazole.
RitonavirThe metabolism of Pantoprazole can be increased when combined with Ritonavir.
SaquinavirThe serum concentration of Saquinavir can be increased when it is combined with Pantoprazole.
SaxagliptinThe serum concentration of Saxagliptin can be decreased when it is combined with Pantoprazole.
SertralineThe metabolism of Pantoprazole can be decreased when combined with Sertraline.
SofosbuvirThe serum concentration of Sofosbuvir can be decreased when it is combined with Pantoprazole.
StiripentolThe metabolism of Pantoprazole can be decreased when combined with Stiripentol.
TacrolimusThe serum concentration of Tacrolimus can be increased when it is combined with Pantoprazole.
TiclopidineThe metabolism of Pantoprazole can be decreased when combined with Ticlopidine.
TiludronateThe therapeutic efficacy of Tiludronate can be decreased when used in combination with Pantoprazole.
TipranavirThe serum concentration of Pantoprazole can be decreased when it is combined with Tipranavir.
TopotecanThe serum concentration of Topotecan can be increased when it is combined with Pantoprazole.
TranylcypromineThe metabolism of Pantoprazole can be decreased when combined with Tranylcypromine.
VoriconazoleThe serum concentration of Pantoprazole can be increased when it is combined with Voriconazole.
ZoledronateThe therapeutic efficacy of Zoledronate can be decreased when used in combination with Pantoprazole.
Food Interactions
  • Take without regard to meals.

Targets

1. Potassium-transporting ATPase alpha chain 1

Kind: Protein

Organism: Human

Pharmacological action: yes

Actions: inhibitor

Components

Name UniProt ID Details
Potassium-transporting ATPase alpha chain 1 P20648 Details

References:

  1. Moreira Dias L: Pantoprazole: a proton pump inhibitor. Clin Drug Investig. 2009;29 Suppl 2:3-12. Pubmed
  2. Cheer SM, Prakash A, Faulds D, Lamb HM: Pantoprazole: an update of its pharmacological properties and therapeutic use in the management of acid-related disorders. Drugs. 2003;63(1):101-33. Pubmed
  3. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed

Enzymes

1. Cytochrome P450 2C19

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inhibitor

Components

Name UniProt ID Details
Cytochrome P450 2C19 P33261 Details

References:

  1. Flockhart DA. Drug Interactions: Cytochrome P450 Drug Interaction Table. Indiana University School of Medicine (2007). Accessed May 28, 2010.
  2. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed
  3. Lexicomp

2. Cytochrome P450 3A4

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inducer

Components

Name UniProt ID Details
Cytochrome P450 3A4 P08684 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

3. Cytochrome P450 2C9

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Cytochrome P450 2C9 P11712 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

4. Cytochrome P450 1A2

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inducer

Components

Name UniProt ID Details
Cytochrome P450 1A2 P05177 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

Transporters

1. Multidrug resistance protein 1

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Multidrug resistance protein 1 P08183 Details

References:

  1. Pauli-Magnus C, Rekersbrink S, Klotz U, Fromm MF: Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein. Naunyn Schmiedebergs Arch Pharmacol. 2001 Dec;364(6):551-7. Pubmed

2. ATP-binding cassette sub-family G member 2

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
ATP-binding cassette sub-family G member 2 Q9UNQ0 Details

References:

  1. Breedveld P, Zelcer N, Pluim D, Sonmezer O, Tibben MM, Beijnen JH, Schinkel AH, van Tellingen O, Borst P, Schellens JH: Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. Cancer Res. 2004 Aug 15;64(16):5804-11. Pubmed
  2. Suzuki K, Doki K, Homma M, Tamaki H, Hori S, Ohtani H, Sawada Y, Kohda Y: Co-administration of proton pump inhibitors delays elimination of plasma methotrexate in high-dose methotrexate therapy. Br J Clin Pharmacol. 2009 Jan;67(1):44-9. Epub 2008 Nov 17. Pubmed
  3. Dahan A, Amidon GL: Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting. Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G371-7. Epub 2009 Jun 18. Pubmed

3. Solute carrier organic anion transporter family member 1B1

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Solute carrier organic anion transporter family member 1B1 Q9Y6L6 Details

References:

  1. Oostendorp RL, van de Steeg E, van der Kruijssen CM, Beijnen JH, Kenworthy KE, Schinkel AH, Schellens JH: Organic anion-transporting polypeptide 1B1 mediates transport of Gimatecan and BNP1350 and can be inhibited by several classic ATP-binding cassette (ABC) B1 and/or ABCG2 inhibitors. Drug Metab Dispos. 2009 Apr;37(4):917-23. Epub 2009 Jan 12. Pubmed

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Drug created on June 13, 2005 07:24 / Updated on September 16, 2013 17:08