Sulfoxides

Name
Sulfoxides
Accession Number
DBCAT000769
Description

Organic compounds that have the general formula R-SO-R. They are obtained by oxidation of mercaptans (analogous to the ketones). (From Hackh's Chemical Dictionary, 4th ed)

Drugs
DrugDrug Description
PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Dimethyl sulfoxideA reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DexlansoprazoleA proton pump inhibitor used to treat erosive esophagitis, heartburn, and gastroesophageal reflux disease (GERD).
IlaprazoleIlaprazole has been investigated in Helicobacter Infections.
AGN-201904Agn 201904 has been used in trials studying the prevention of Peptic Ulcer.
DexrabeprazoleA proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers.
Dimethyl sulfoneNot Annotated
Lansoprazole sulfoneNot Annotated
Drugs & Drug Targets
DrugTargetType
PantoprazolePotassium-transporting ATPase alpha chain 1target
PantoprazoleCytochrome P450 2C19enzyme
PantoprazoleCytochrome P450 3A4enzyme
PantoprazoleP-glycoprotein 1transporter
PantoprazoleATP-binding cassette sub-family G member 2transporter
PantoprazoleSolute carrier family 22 member 8transporter
PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
OmeprazolePotassium-transporting ATPase alpha chain 1target
OmeprazoleCytochrome P450 2C19enzyme
OmeprazoleCytochrome P450 3A4enzyme
OmeprazoleCytochrome P450 2C9enzyme
OmeprazoleCytochrome P450 1A2enzyme
OmeprazoleCanalicular multispecific organic anion transporter 2transporter
OmeprazoleP-glycoprotein 1transporter
OmeprazoleATP-binding cassette sub-family G member 2transporter
OmeprazoleCytochrome P450 1A1enzyme
OmeprazoleCytochrome P450 1B1enzyme
OmeprazoleCytochrome P450 2C18enzyme
OmeprazoleCytochrome P450 2C8enzyme
OmeprazoleCytochrome P450 2D6enzyme
OmeprazoleAryl hydrocarbon receptortarget
LansoprazolePotassium-transporting ATPase alpha chain 1target
LansoprazoleCytochrome P450 2C19enzyme
LansoprazoleCytochrome P450 2C9enzyme
LansoprazoleCytochrome P450 3A4enzyme
LansoprazoleP-glycoprotein 1transporter
LansoprazoleATP-binding cassette sub-family G member 2transporter
LansoprazoleCytochrome P450 1A1enzyme
LansoprazoleCytochrome P450 1B1enzyme
LansoprazoleCytochrome P450 2C18enzyme
LansoprazoleCytochrome P450 2C8enzyme
LansoprazoleCytochrome P450 2D6enzyme
LansoprazoleMicrotubule-associated protein tautarget
LansoprazoleSolute carrier family 22 member 8transporter
LansoprazoleSolute carrier family 22 member 1transporter
LansoprazoleSolute carrier family 22 member 2transporter
LansoprazoleSolute carrier family 22 member 3transporter
Dimethyl sulfoxideTransthyretincarrier
Dimethyl sulfoxideCytochrome P450 2C19enzyme
Dimethyl sulfoxideCytochrome P450 2D6enzyme
Dimethyl sulfoxideCytochrome P450 3A4enzyme
Dimethyl sulfoxideInterleukin-5 receptor subunit alphatarget
Dimethyl sulfoxideMucin-16target
Dimethyl sulfoxideMyc proto-oncogene proteintarget
EsomeprazolePotassium-transporting ATPase alpha chain 1target
EsomeprazoleCytochrome P450 2C19enzyme
EsomeprazoleCytochrome P450 3A4enzyme
EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
EsomeprazoleP-glycoprotein 1transporter
EsomeprazoleSolute carrier family 22 member 8transporter
RabeprazolePotassium-transporting ATPase alpha chain 1target
RabeprazoleCytochrome P450 3A4enzyme
RabeprazoleCytochrome P450 2C19enzyme
RabeprazoleATP-binding cassette sub-family G member 2transporter
RabeprazoleCytochrome P450 1A1enzyme
RabeprazoleCytochrome P450 1A2enzyme
RabeprazoleCytochrome P450 2C9enzyme
RabeprazoleCytochrome P450 2D6enzyme
RabeprazoleCytochrome P450 2C8enzyme
DexlansoprazolePotassium-transporting ATPase alpha chain 1target
DexlansoprazoleCytochrome P450 2C19enzyme
DexlansoprazoleCytochrome P450 3A4enzyme
DexlansoprazolePotassium-transporting ATPase subunit betatarget
DexlansoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DexrabeprazoleCytochrome P450 2C19enzyme