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Identification
NameRopinirole
Accession NumberDB00268  (APRD00302)
TypeSmall Molecule
GroupsApproved, Investigational
DescriptionRopinirole is a non-ergoline dopamine agonist, manufactured by GlaxoSmithKline. It is used in the treatment of Parkinson's disease, and is also one of two medications in the United States with an FDA-approved indication for the treatment of restless legs syndrome (the other being Pramipexole). [Wikipedia]
Structure
Thumb
Synonyms
Ropinirol
Ropinirole
Ropinirolum
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Act Ropiniroletablet5 mgoralActavis Pharma Company2009-07-22Not applicableCanada
Act Ropiniroletablet0.25 mgoralActavis Pharma Company2009-07-22Not applicableCanada
Act Ropiniroletablet1 mgoralActavis Pharma Company2009-07-22Not applicableCanada
Act Ropiniroletablet2 mgoralActavis Pharma Company2009-07-22Not applicableCanada
Dom-ropiniroletablet5.0 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-ropiniroletablet0.25 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-ropiniroletablet0.5 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-ropiniroletablet1.0 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-ropiniroletablet2.0 mgoralDominion PharmacalNot applicableNot applicableCanada
Jamp-ropiniroletablet5.0 mgoralJamp Pharma Corporation2010-06-16Not applicableCanada
Jamp-ropiniroletablet0.25 mgoralJamp Pharma Corporation2010-06-16Not applicableCanada
Jamp-ropiniroletablet1.0 mgoralJamp Pharma Corporation2010-06-16Not applicableCanada
Jamp-ropiniroletablet2.0 mgoralJamp Pharma Corporation2010-06-16Not applicableCanada
PHL-ropiniroletablet2.0 mgoralPharmel IncNot applicableNot applicableCanada
PHL-ropiniroletablet0.25 mgoralPharmel IncNot applicableNot applicableCanada
PHL-ropiniroletablet5.0 mgoralPharmel IncNot applicableNot applicableCanada
PHL-ropiniroletablet0.5 mgoralPharmel IncNot applicableNot applicableCanada
PHL-ropiniroletablet1.0 mgoralPharmel IncNot applicableNot applicableCanada
PMS-ropiniroletablet5.0 mgoralPharmascience Inc2009-07-22Not applicableCanada
PMS-ropiniroletablet0.25 mgoralPharmascience Inc2009-07-22Not applicableCanada
PMS-ropiniroletablet1.0 mgoralPharmascience Inc2009-07-22Not applicableCanada
PMS-ropiniroletablet0.5 mgoralPharmascience IncNot applicableNot applicableCanada
PMS-ropiniroletablet2.0 mgoralPharmascience Inc2009-07-22Not applicableCanada
Ran-ropiniroletablet5.0 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-07-22Not applicableCanada
Ran-ropiniroletablet0.25 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-07-22Not applicableCanada
Ran-ropiniroletablet1.0 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-07-22Not applicableCanada
Ran-ropiniroletablet0.5 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Ran-ropiniroletablet2.0 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-07-22Not applicableCanada
Requiptablet, film coated1 mg/1oralGlaxo Smith Kline Llc1997-10-01Not applicableUs
Requiptablet0.25 mgoralGlaxosmithkline Inc1997-09-29Not applicableCanada
Requiptablet, film coated4 mg/1oralGlaxo Smith Kline Llc1999-09-21Not applicableUs
Requiptablet, film coated2 mg/1oralGlaxo Smith Kline Llc1997-10-03Not applicableUs
Requiptablet1 mgoralGlaxosmithkline Inc1997-09-25Not applicableCanada
Requiptablet, film coated.25 mg/1oralGlaxo Smith Kline Llc1997-10-10Not applicableUs
Requiptablet, film coated5 mg/1oralGlaxo Smith Kline Llc1997-10-10Not applicableUs
Requiptablet2 mgoralGlaxosmithkline Inc1997-09-25Not applicableCanada
Requiptablet, film coated1 mg/1oralPd Rx Pharmaceuticals, Inc.1997-10-01Not applicableUs
Requiptablet, film coated.5 mg/1oralGlaxo Smith Kline Llc1997-10-10Not applicableUs
Requiptablet, film coated3 mg/1oralGlaxo Smith Kline Llc2001-06-19Not applicableUs
Requiptablet5 mgoralGlaxosmithkline Inc1997-09-25Not applicableCanada
Requiptablet, film coated1 mg/1oralbryant ranch prepack1997-10-01Not applicableUs
Requip XLtablet, film coated, extended release12 mg/1oralGlaxo Smith Kline Llc2008-11-20Not applicableUs
Requip XLtablet, film coated, extended release8 mg/1oralGlaxo Smith Kline Llc2008-06-30Not applicableUs
Requip XLtablet, film coated, extended release6 mg/1oralGlaxo Smith Kline Llc2009-08-03Not applicableUs
Requip XLtablet, film coated, extended release2 mg/1oralPhysicians Total Care, Inc.2009-12-18Not applicableUs
Requip XLtablet, film coated, extended release2 mg/1oralGlaxo Smith Kline Llc2008-06-30Not applicableUs
Requip XLtablet, film coated, extended release4 mg/1oralGlaxo Smith Kline Llc2008-06-30Not applicableUs
Ropiniroletablet5 mgoralSanis Health Inc2010-07-26Not applicableCanada
Ropiniroletablet0.25 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Ropiniroletablet2 mgoralSanis Health Inc2010-07-262014-08-01Canada
Ropiniroletablet1 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Ropiniroletablet0.25 mgoralSanis Health Inc2010-07-26Not applicableCanada
Ropiniroletablet2 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Ropiniroletablet1 mgoralSanis Health Inc2010-07-26Not applicableCanada
Ropiniroletablet5 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Ropinirole Tabletstablet0.5 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Ropinirole Tabletstablet1.0 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Ropinirole Tabletstablet2.0 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Ropinirole Tabletstablet0.25 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Ropinirole Tabletstablet5.0 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo-ropiniroletablet5.0 mgoralApotex IncNot applicableNot applicableCanada
Apo-ropiniroletablet2.0 mgoralApotex IncNot applicableNot applicableCanada
Apo-ropiniroletablet0.25 mgoralApotex IncNot applicableNot applicableCanada
Apo-ropiniroletablet3.0 mgoralApotex IncNot applicableNot applicableCanada
Apo-ropiniroletablet0.5 mgoralApotex IncNot applicableNot applicableCanada
Apo-ropiniroletablet4.0 mgoralApotex IncNot applicableNot applicableCanada
Apo-ropiniroletablet1.0 mgoralApotex IncNot applicableNot applicableCanada
Ropiniroletablet, film coated, extended release12 mg/1oralTrigen Laboratories, LLC2013-03-14Not applicableUs
Ropiniroletablet, film coated, extended release6 mg/1oralActavis Pharma, Inc.2012-08-23Not applicableUs
Ropiniroletablet, film coated, extended release4 mg/1oralDr. Reddys Laboratories Limited2012-06-06Not applicableUs
Ropiniroletablet.5 mg/1oralCarilion Materials Management2008-05-05Not applicableUs
Ropiniroletablet, film coated3 mg/1oralGlenmark Pharmaceuticals Inc., Usa2010-02-25Not applicableUs
Ropiniroletablet, film coated, extended release8 mg/1oralSandoz Inc2012-06-06Not applicableUs
Ropiniroletablet.25 mg/1oralRoxane Laboratories, Inc2008-05-05Not applicableUs
Ropiniroletablet, film coated.5 mg/1oralHeritage Pharmaceuticals Inc.2009-09-18Not applicableUs
Ropiniroletablet, film coated5 mg/1oralApotex Corp.2013-03-29Not applicableUs
Ropiniroletablet, film coated, extended release8 mg/1oralAlembic Pharmaceuticals Limited2013-03-14Not applicableUs
Ropiniroletablet, film coated, extended release12 mg/1oralActavis Pharma, Inc.2012-08-23Not applicableUs
Ropiniroletablet, film coated1 mg/1oralApotex Corp.2013-03-29Not applicableUs
Ropiniroletablet, film coated.5 mg/1oralGlenmark Pharmaceuticals Inc., Usa2010-02-25Not applicableUs
Ropiniroletablet, film coated, extended release2 mg/1oralSandoz Inc2012-06-06Not applicableUs
Ropiniroletablet, film coated, extended release4 mg/1oralTrigen Laboratories, LLC2013-03-14Not applicableUs
Ropiniroletablet3 mg/1oralRoxane Laboratories, Inc2008-05-05Not applicableUs
Ropiniroletablet, film coated4 mg/1oralHeritage Pharmaceuticals Inc.2009-10-09Not applicableUs
Ropiniroletablet, film coated, extended release2 mg/1oralActavis Pharma, Inc.2012-08-23Not applicableUs
Ropiniroletablet, film coated, extended release8 mg/1oralDr. Reddys Laboratories Limited2012-06-06Not applicableUs
Ropiniroletablet1 mg/1oralCarilion Materials Management2008-05-05Not applicableUs
Ropiniroletablet, film coated4 mg/1oralGlenmark Pharmaceuticals Inc., Usa2010-02-25Not applicableUs
Ropiniroletablet, film coated, extended release2 mg/1oralAlembic Pharmaceuticals Limited2013-03-14Not applicableUs
Ropiniroletablet, film coated, extended release12 mg/1oralSandoz Inc2012-06-06Not applicableUs
Ropiniroletablet.5 mg/1oralRoxane Laboratories, Inc2008-05-05Not applicableUs
Ropiniroletablet, film coated1 mg/1oralHeritage Pharmaceuticals Inc.2009-09-18Not applicableUs
Ropiniroletablet, film coated, extended release12 mg/1oralAlembic Pharmaceuticals Limited2013-03-14Not applicableUs
Ropiniroletablet2 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-05-05Not applicableUs
Ropiniroletablet, film coated2 mg/1oralApotex Corp.2013-03-29Not applicableUs
Ropiniroletablet, film coated1 mg/1oralGlenmark Pharmaceuticals Inc., Usa2010-02-25Not applicableUs
Ropiniroletablet, film coated, extended release4 mg/1oralSandoz Inc2012-06-06Not applicableUs
Ropiniroletablet, film coated, extended release6 mg/1oralTrigen Laboratories, LLC2013-03-14Not applicableUs
Ropiniroletablet4 mg/1oralRoxane Laboratories, Inc2008-05-05Not applicableUs
Ropiniroletablet, film coated5 mg/1oralHeritage Pharmaceuticals Inc.2009-09-18Not applicableUs
Ropiniroletablet, film coated, extended release4 mg/1oralActavis Pharma, Inc.2012-08-23Not applicableUs
Ropiniroletablet, film coated, extended release6 mg/1oralDr. Reddys Laboratories Limited2012-06-06Not applicableUs
Ropiniroletablet, film coated.25 mg/1oralApotex Corp.2013-03-29Not applicableUs
Ropiniroletablet, film coated5 mg/1oralGlenmark Pharmaceuticals Inc., Usa2010-02-25Not applicableUs
Ropiniroletablet, film coated, extended release4 mg/1oralAlembic Pharmaceuticals Limited2013-03-14Not applicableUs
Ropiniroletablet1 mg/1oralRoxane Laboratories, Inc2008-05-05Not applicableUs
Ropiniroletablet, film coated2 mg/1oralHeritage Pharmaceuticals Inc.2009-09-18Not applicableUs
Ropiniroletablet, film coated3 mg/1oralApotex Corp.2013-03-29Not applicableUs
Ropiniroletablet1 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-05-05Not applicableUs
Ropiniroletablet, film coated, extended release2 mg/1oralDr. Reddys Laboratories Limited2012-06-06Not applicableUs
Ropiniroletablet, film coated1 mg/1oralLake Erie Medical DBA Quality Care Products LLC2010-02-25Not applicableUs
Ropiniroletablet.25 mg/1oralCarilion Materials Management2008-05-05Not applicableUs
Ropiniroletablet, film coated2 mg/1oralGlenmark Pharmaceuticals Inc., Usa2010-02-25Not applicableUs
Ropiniroletablet, film coated, extended release6 mg/1oralSandoz Inc2012-06-06Not applicableUs
Ropiniroletablet, film coated, extended release8 mg/1oralTrigen Laboratories, LLC2013-03-14Not applicableUs
Ropiniroletablet5 mg/1oralRoxane Laboratories, Inc2008-05-05Not applicableUs
Ropiniroletablet, film coated, extended release6 mg/1oralAlembic Pharmaceuticals Limited2013-03-14Not applicableUs
Ropiniroletablet, film coated, extended release8 mg/1oralActavis Pharma, Inc.2012-08-23Not applicableUs
Ropiniroletablet, film coated, extended release12 mg/1oralDr. Reddys Laboratories Limited2012-06-06Not applicableUs
Ropiniroletablet, film coated.5 mg/1oralApotex Corp.2013-03-29Not applicableUs
Ropiniroletablet, film coated2 mg/1oralDispensing Solutions, Inc.2010-02-25Not applicableUs
Ropiniroletablet, film coated.25 mg/1oralGlenmark Pharmaceuticals Inc., Usa2010-02-25Not applicableUs
Ropiniroletablet, film coated, extended release2 mg/1oralTrigen Laboratories, LLC2013-03-14Not applicableUs
Ropiniroletablet2 mg/1oralRoxane Laboratories, Inc2008-05-05Not applicableUs
Ropiniroletablet, film coated3 mg/1oralHeritage Pharmaceuticals Inc.2009-09-18Not applicableUs
Ropiniroletablet.25 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-05-05Not applicableUs
Ropiniroletablet, film coated4 mg/1oralApotex Corp.2013-03-29Not applicableUs
Ropiniroletablet, film coated.25 mg/1oralHeritage Pharmaceuticals Inc.2009-09-18Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralAlembic Pharmaceuticals Limited2013-09-12Not applicableUs
Ropinirole Hydrochloridetablet.25 mg/1oralMylan Pharmaceuticals Inc.2008-05-05Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release2 mg/1oralAv Kare, Inc.2013-09-13Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release12 mg/1oralWockhardt Limited2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralZhejiang Huahai Pharmaceutical Co., Ltd.2011-08-10Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release8 mg/1oralWockhardt USA LLC.2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralMajor Pharmaceuticals2009-07-08Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralSolco healthcare U.S., LLC2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release8 mg/1oralMylan Pharmaceuticals Inc.2012-10-16Not applicableUs
Ropinirole Hydrochloridetablet, coated1 mg/1oralPhysicians Total Care, Inc.2008-05-21Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralWockhardt Limited2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralWockhardt USA LLC.2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralCadila Healthcare Limited2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralZydus Pharmaceuticals (USA) Inc.2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralAvera Mc Kennan Hospital2015-03-11Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralAlembic Pharmaceuticals Inc.2016-01-29Not applicableUs
Ropinirole Hydrochloridetablet.5 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-10-27Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralAmerican Health Packaging2013-07-052016-01-05Us
Ropinirole Hydrochloridetablet, film coated1 mg/1oralMajor Pharmaceuticals2009-07-08Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralRebel Distributors Corp2009-09-18Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralAlembic Pharmaceuticals Limited2013-09-12Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release4 mg/1oralWatson Laboratories, Inc.2012-06-06Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralCardinal Health2014-01-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release12 mg/1oralAv Kare, Inc.2013-09-13Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralZhejiang Huahai Pharmaceutical Co., Ltd.2011-08-10Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralCadila Healthcare Limited2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralZydus Pharmaceuticals (USA) Inc.2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralAmerican Health Packaging2014-01-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralAlembic Pharmaceuticals Inc.2016-01-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralSolco healthcare U.S., LLC2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet3 mg/1oralMylan Pharmaceuticals Inc.2008-05-05Not applicableUs
Ropinirole Hydrochloridetablet, coated.5 mg/1oralPhysicians Total Care, Inc.2008-10-22Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release2 mg/1oralWockhardt Limited2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralbryant ranch prepack2009-09-18Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralWockhardt USA LLC.2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet1 mg/1oralSTAT Rx USA LLC2009-09-17Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralAlembic Pharmaceuticals Limited2013-09-12Not applicableUs
Ropinirole Hydrochloridetablet.5 mg/1oralMylan Pharmaceuticals Inc.2008-05-05Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release4 mg/1oralAv Kare, Inc.2013-09-13Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release6 mg/1oralWockhardt Limited2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralZhejiang Huahai Pharmaceutical Co., Ltd.2011-08-10Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release12 mg/1oralWockhardt USA LLC.2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralMajor Pharmaceuticals2014-10-01Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralSolco healthcare U.S., LLC2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release12 mg/1oralMylan Pharmaceuticals Inc.2012-10-16Not applicableUs
Ropinirole Hydrochloridetablet, coated2 mg/1oralPhysicians Total Care, Inc.2008-06-27Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralWockhardt Limited2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralbryant ranch prepack2009-09-18Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralWockhardt USA LLC.2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralCadila Healthcare Limited2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralZydus Pharmaceuticals (USA) Inc.2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralAlembic Pharmaceuticals Inc.2016-01-29Not applicableUs
Ropinirole Hydrochloridetablet1 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-10-27Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralCadila Healthcare Limited2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralZydus Pharmaceuticals (USA) Inc.2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralAmerican Health Packaging2013-07-052016-01-05Us
Ropinirole Hydrochloridetablet, film coated2 mg/1oral; oralMajor Pharmaceuticals2009-07-08Not applicableUs
Ropinirole Hydrochloridetablet, coated1 mg/1oralRebel Distributors Corp2008-05-21Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release2 mg/1oralMylan Pharmaceuticals Inc.2012-10-16Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralAlembic Pharmaceuticals Limited2013-09-12Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release8 mg/1oralWatson Laboratories, Inc.2012-06-06Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralWockhardt Limited2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralZhejiang Huahai Pharmaceutical Co., Ltd.2011-08-10Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralbryant ranch prepack2009-09-18Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release2 mg/1oralWockhardt USA LLC.2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralAmerican Health Packaging2014-01-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralAvera Mc Kennan Hospital2015-06-05Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralSolco healthcare U.S., LLC2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet4 mg/1oralMylan Pharmaceuticals Inc.2008-05-05Not applicableUs
Ropinirole Hydrochloridetablet, coated5 mg/1oralPhysicians Total Care, Inc.2010-09-08Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release4 mg/1oralWockhardt Limited2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralMajor Pharmaceuticals2009-07-08Not applicableUs
Ropinirole Hydrochloridetablet2 mg/1oralSTAT Rx USA LLC2009-09-17Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralAlembic Pharmaceuticals Limited2013-09-12Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release2 mg/1oralWatson Laboratories, Inc.2012-06-06Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release6 mg/1oralAv Kare, Inc.2013-09-13Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralZhejiang Huahai Pharmaceutical Co., Ltd.2011-08-10Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release6 mg/1oralWockhardt USA LLC.2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralDispensing Solutions, Inc.2009-09-18Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralAlembic Pharmaceuticals Inc.2016-01-29Not applicableUs
Ropinirole Hydrochloridetablet2 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-10-27Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralMajor Pharmaceuticals2014-10-01Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralSolco healthcare U.S., LLC2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet1 mg/1oralMylan Pharmaceuticals Inc.2008-05-05Not applicableUs
Ropinirole Hydrochloridetablet, coated4 mg/1oralPhysicians Total Care, Inc.2008-07-02Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralWockhardt Limited2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralbryant ranch prepack2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralWockhardt USA LLC.2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralAmerican Health Packaging2014-01-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralZydus Pharmaceuticals (USA) Inc.2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralWockhardt USA LLC.2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralCadila Healthcare Limited2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralZydus Pharmaceuticals (USA) Inc.2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralAmerican Health Packaging2013-07-052016-01-05Us
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralAlembic Pharmaceuticals Inc.2016-01-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralMajor Pharmaceuticals2009-07-08Not applicableUs
Ropinirole Hydrochloridetablet, coated5 mg/1oralRebel Distributors Corp2008-05-21Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release4 mg/1oralMylan Pharmaceuticals Inc.2012-10-16Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralAlembic Pharmaceuticals Limited2013-09-12Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release6 mg/1oralWatson Laboratories, Inc.2012-06-06Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralWockhardt Limited2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet5 mg/1oralMylan Pharmaceuticals Inc.2008-05-05Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release8 mg/1oralWockhardt Limited2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralZhejiang Huahai Pharmaceutical Co., Ltd.2011-08-10Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release4 mg/1oralWockhardt USA LLC.2012-08-15Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralSolco healthcare U.S., LLC2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralAvera Mc Kennan Hospital2015-03-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralMajor Pharmaceuticals2009-07-08Not applicableUs
Ropinirole Hydrochloridetablet, coated.25 mg/1oralRebel Distributors Corp2008-05-21Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralAlembic Pharmaceuticals Limited2013-09-12Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release12 mg/1oralWatson Laboratories, Inc.2012-06-06Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release8 mg/1oralAv Kare, Inc.2013-09-13Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralZhejiang Huahai Pharmaceutical Co., Ltd.2011-08-10Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralCadila Healthcare Limited2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralAlembic Pharmaceuticals Inc.2016-01-29Not applicableUs
Ropinirole Hydrochloridetablet3 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-10-27Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralSolco healthcare U.S., LLC2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet2 mg/1oralMylan Pharmaceuticals Inc.2008-05-05Not applicableUs
Ropinirole Hydrochloridetablet, coated.25 mg/1oralPhysicians Total Care, Inc.2008-10-22Not applicableUs
Ropinirole Hydrochloridetablet, film coated5 mg/1oralWockhardt Limited2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralbryant ranch prepack2011-09-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralWockhardt USA LLC.2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralAmerican Health Packaging2014-01-20Not applicableUs
Ropinirole Hydrochloridetablet, film coated.25 mg/1oralAidarex Pharmaceuticals LLC2009-09-18Not applicableUs
Ropinirole Hydrochloridetablet.25 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-10-27Not applicableUs
Ropinirole Hydrochloridetablet, film coated1 mg/1oralWockhardt Limited2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralWockhardt USA LLC.2008-05-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated3 mg/1oralCadila Healthcare Limited2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralZydus Pharmaceuticals (USA) Inc.2009-09-23Not applicableUs
Ropinirole Hydrochloridetablet, film coated2 mg/1oralAmerican Health Packaging2013-07-052016-01-05Us
Ropinirole Hydrochloridetablet, film coated.5 mg/1oralAlembic Pharmaceuticals Inc.2016-01-29Not applicableUs
Ropinirole Hydrochloridetablet, film coated4 mg/1oralMajor Pharmaceuticals2009-07-08Not applicableUs
Ropinirole Hydrochloridetablet, film coated, extended release6 mg/1oralMylan Pharmaceuticals Inc.2012-10-16Not applicableUs
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International Brands
NameCompany
AdartrelNot Available
ReQuip CRGlaxoSmithKline
RonirolNot Available
Brand mixturesNot Available
Salts
Name/CASStructureProperties
Ropinirole Hydrochloride
Thumb
  • InChI Key: XDXHAEQXIBQUEZ-UHFFFAOYSA-N
  • Monoisotopic Mass: 296.165541139
  • Average Mass: 296.836
DBSALT000390
Categories
UNII030PYR8953
CAS number91374-21-9
WeightAverage: 260.3746
Monoisotopic: 260.1888634
Chemical FormulaC16H24N2O
InChI KeyInChIKey=UHSKFQJFRQCDBE-UHFFFAOYSA-N
InChI
InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)
IUPAC Name
4-[2-(dipropylamino)ethyl]-2,3-dihydro-1H-indol-2-one
SMILES
CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as indolines. These are compounds containing an indole moiety, which consists of pyrrolidine ring fused to benzene to form 2,3-dihydroindole.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassIndoles and derivatives
Sub ClassIndolines
Direct ParentIndolines
Alternative Parents
Substituents
  • Phenethylamine
  • Dihydroindole
  • Aralkylamine
  • Benzenoid
  • Tertiary aliphatic amine
  • Tertiary amine
  • Secondary carboxylic acid amide
  • Lactam
  • Carboxamide group
  • Azacycle
  • Carboxylic acid derivative
  • Carboxylic acid amide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Carbonyl group
  • Amine
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Pharmacology
IndicationFor the treatment of the signs and symptoms of idiopathic Parkinson's disease. Also used for the treatment of restless legs syndrome.
PharmacodynamicsRopinirole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 subfamily of dopamine receptors, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. The relevance of D3 receptor binding in Parkinson's disease is unknown. The mechanism of ropinirole-induced postural hypotension is presumed to be due to a D2 -mediated blunting of the noradrenergic response to standing and subsequent decrease in peripheral vascular resistance.
Mechanism of actionRopinirole binds the dopamine receptors D3 and D2. Although the precise mechanism of action of ropinirole as a treatment for Parkinson's disease is unknown, it is believed to be related to its ability to stimulate these receptors in the striatum. This conclusion is supported by electrophysiologic studies in animals that have demonstrated that ropinirole influences striatal neuronal firing rates via activation of dopamine receptors in the striatum and the substantia nigra, the site of neurons that send projections to the striatum.
Related Articles
AbsorptionAbsolute bioavailability is 55%, indicating a first pass effect. Food does not affect the extent of absorption.
Volume of distribution
  • 7.5 L/kg
  • 525 L
Protein binding40% bound to plasma proteins with a blood-to-plasma ratio of 1:1.
Metabolism

Hepatic. Ropinirole is extensively metabolized to inactive metabolites via N -despropylation and hydroxylation pathways, largely by the P450 isoenzyme CYP1A2. N-despropyl ropinirole is the predominant metabolite found in urine (40%), followed by the carboxylic acid metabolite (10%), and the glucuronide of the hydroxy metabolite (10%).

SubstrateEnzymesProduct
Ropinirole
Not Available
N-despropyl ropiniroleDetails
Route of eliminationRopinirole is extensively metabolized by the liver to inactive metabolites, and less than 10% of the administered dose is excreted as unchanged drug in urine.
Half life6 hours
Clearance
  • 47 L/hr [after oral administration to Parkinson’s disease patients and patients with Restless Legs Syndrome]
ToxicitySymptoms of overdose include agitation, chest pain, confusion, drowsiness, facial muscle movements, grogginess, increased jerkiness of movement, symptoms of low blood pressure (dizziness, light-headedness)upon standing, nausea, and vomiting.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+1.0
Blood Brain Barrier+0.9971
Caco-2 permeable+0.6087
P-glycoprotein substrateSubstrate0.7604
P-glycoprotein inhibitor IInhibitor0.5458
P-glycoprotein inhibitor IINon-inhibitor0.8641
Renal organic cation transporterNon-inhibitor0.602
CYP450 2C9 substrateNon-substrate0.8593
CYP450 2D6 substrateNon-substrate0.9116
CYP450 3A4 substrateSubstrate0.6903
CYP450 1A2 substrateNon-inhibitor0.9045
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorInhibitor0.8932
CYP450 2C19 inhibitorNon-inhibitor0.9025
CYP450 3A4 inhibitorNon-inhibitor0.8309
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.6959
Ames testNon AMES toxic0.7302
CarcinogenicityNon-carcinogens0.905
BiodegradationNot ready biodegradable0.9966
Rat acute toxicity2.6400 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.8959
hERG inhibition (predictor II)Non-inhibitor0.7066
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Smithkline beecham corp dba glaxosmithkline
  • Glaxosmithkline
  • Alembic ltd
  • Corepharma llc
  • Glenmark generics ltd
  • Huahai us inc
  • Mylan pharmaceuticals inc
  • Roxane laboratories inc
  • Teva pharmaceuticals usa inc
  • Wockhardt ltd
  • Zydus pharmaceuticals usa inc
Packagers
Dosage forms
FormRouteStrength
Tabletoral3.0 mg
Tabletoral4.0 mg
Tabletoral0.5 mg
Tabletoral1.0 mg
Tabletoral2.0 mg
Tabletoral5.0 mg
Tabletoral0.25 mg
Tabletoral1 mg
Tabletoral2 mg
Tabletoral5 mg
Tablet, film coatedoral.25 mg/1
Tablet, film coatedoral.5 mg/1
Tablet, film coatedoral1 mg/1
Tablet, film coatedoral2 mg/1
Tablet, film coatedoral3 mg/1
Tablet, film coatedoral4 mg/1
Tablet, film coatedoral5 mg/1
Tablet, film coated, extended releaseoral12 mg/1
Tablet, film coated, extended releaseoral2 mg/1
Tablet, film coated, extended releaseoral4 mg/1
Tablet, film coated, extended releaseoral6 mg/1
Tablet, film coated, extended releaseoral8 mg/1
Tabletoral.25 mg/1
Tabletoral.5 mg/1
Tabletoral1 mg/1
Tabletoral2 mg/1
Tabletoral3 mg/1
Tabletoral4 mg/1
Tabletoral5 mg/1
Tablet, coatedoral.25 mg/1
Tablet, coatedoral.5 mg/1
Tablet, coatedoral1 mg/1
Tablet, coatedoral2 mg/1
Tablet, coatedoral4 mg/1
Tablet, coatedoral5 mg/1
Tablet, film coatedoral; oral2 mg/1
Prices
Unit descriptionCostUnit
Requip XL 12 mg 24 Hour tablet14.92USD tablet
Requip xl 12 mg tablet14.35USD tablet
Requip XL 8 mg 24 Hour tablet8.96USD tablet
Requip xl 6 mg tablet8.61USD tablet
Requip xl 8 mg tablet8.61USD tablet
Requip XL 4 mg 24 Hour tablet5.97USD tablet
Requip xl 4 mg tablet5.74USD tablet
Requip 5 mg Tablet3.87USD tablet
Requip 3 mg tablet3.41USD tablet
Requip 4 mg tablet3.41USD tablet
Requip 5 mg tablet3.41USD tablet
Requip 0.25 mg tablet3.29USD tablet
Requip 0.5 mg tablet3.29USD tablet
Requip 1 mg tablet3.29USD tablet
Requip 2 mg tablet3.29USD tablet
Requip xl 2 mg tablet2.87USD tablet
Ropinirole hcl 3 mg tablet2.65USD tablet
Ropinirole hcl 4 mg tablet2.65USD tablet
Ropinirole hcl 5 mg tablet2.65USD tablet
Ropinirole hcl 0.25 mg tablet2.55USD tablet
Ropinirole hcl 0.5 mg tablet2.55USD tablet
Ropinirole hcl 1 mg tablet2.55USD tablet
Ropinirole hcl 2 mg tablet2.55USD tablet
Co Ropinirole 5 mg Tablet1.8USD tablet
Pms-Ropinirole 5 mg Tablet1.8USD tablet
Ran-Ropinirole 5 mg Tablet1.8USD tablet
Ropinirole 5 mg Tablet1.8USD tablet
Requip 2 mg Tablet1.41USD tablet
Requip 1 mg Tablet1.28USD tablet
Co Ropinirole 2 mg Tablet0.65USD tablet
Pms-Ropinirole 2 mg Tablet0.65USD tablet
Ran-Ropinirole 2 mg Tablet0.65USD tablet
Ropinirole 2 mg Tablet0.65USD tablet
Co Ropinirole 1 mg Tablet0.59USD tablet
Pms-Ropinirole 1 mg Tablet0.59USD tablet
Ran-Ropinirole 1 mg Tablet0.59USD tablet
Ropinirole 1 mg Tablet0.59USD tablet
Requip 0.25 mg Tablet0.32USD tablet
Co Ropinirole 0.25 mg Tablet0.15USD tablet
Pms-Ropinirole 0.25 mg Tablet0.15USD tablet
Ran-Ropinirole 0.25 mg Tablet0.15USD tablet
Ropinirole 0.25 mg Tablet0.15USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US5422123 No1995-06-062012-06-06Us
US7927624 No2001-12-022021-12-02Us
US8303986 No2001-04-122021-04-12Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point243-250 °CNot Available
water solubility133 mg/mLNot Available
logP2.70ADLARD,M ET AL. (1995)
Predicted Properties
PropertyValueSource
Water Solubility0.353 mg/mLALOGPS
logP3.16ALOGPS
logP3.06ChemAxon
logS-2.9ALOGPS
pKa (Strongest Acidic)13.24ChemAxon
pKa (Strongest Basic)10.17ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area32.34 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity81.43 m3·mol-1ChemAxon
Polarizability31.19 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-0190000000-7e072cf65f341641938cView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03di-3960000000-47d2311adfeeacf4062dView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0006-7900000000-0891c66db163729a5360View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0a4i-0090000000-88c0fa3d93090a0d06c6View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0pb9-3590000000-8fb5fc766313ee6bbd9eView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0k96-9400000000-f1b50dacd59a9bfe90b7View in MoNA
References
Synthesis Reference

DrugSyn.org

US4452808
General ReferencesNot Available
External Links
ATC CodesN04BC04
AHFS Codes
  • 28:36.20.08
PDB EntriesNot Available
FDA labelDownload (267 KB)
MSDSDownload (29.6 KB)
Interactions
Drug Interactions
Drug
4-MethoxyamphetamineThe metabolism of 4-Methoxyamphetamine can be decreased when combined with Ropinirole.
7-Nitroindazole7-Nitroindazole may increase the sedative activities of Ropinirole.
7,8-DICHLORO-1,2,3,4-TETRAHYDROISOQUINOLINEThe metabolism of Ropinirole can be decreased when combined with 7,8-DICHLORO-1,2,3,4-TETRAHYDROISOQUINOLINE.
AbirateroneThe serum concentration of Ropinirole can be increased when it is combined with Abiraterone.
AcebutololRopinirole may increase the atrioventricular blocking (AV block) activities of Acebutolol.
AcenocoumarolThe metabolism of Acenocoumarol can be decreased when combined with Ropinirole.
AcepromazineAcepromazine may increase the sedative activities of Ropinirole.
AceprometazineAceprometazine may increase the sedative activities of Ropinirole.
AcetaminophenThe metabolism of Acetaminophen can be decreased when combined with Ropinirole.
AcetylcholineThe metabolism of Acetylcholine can be decreased when combined with Ropinirole.
adipiplonadipiplon may increase the sedative activities of Ropinirole.
AgomelatineAgomelatine may increase the sedative activities of Ropinirole.
AgomelatineThe serum concentration of Agomelatine can be increased when it is combined with Ropinirole.
AjmalineThe metabolism of Ajmaline can be decreased when combined with Ropinirole.
AlbendazoleThe metabolism of Albendazole can be decreased when combined with Ropinirole.
AlfaxaloneAlfaxalone may increase the sedative activities of Ropinirole.
AlfentanilAlfentanil may increase the sedative activities of Ropinirole.
AlmotriptanThe metabolism of Almotriptan can be decreased when combined with Ropinirole.
AlogliptinThe metabolism of Alogliptin can be decreased when combined with Ropinirole.
AlosetronThe metabolism of Alosetron can be decreased when combined with Ropinirole.
AlphacetylmethadolAlphacetylmethadol may increase the sedative activities of Ropinirole.
AlprazolamAlprazolam may increase the sedative activities of Ropinirole.
AlprenololThe metabolism of Alprenolol can be decreased when combined with Ropinirole.
AmineptineThe therapeutic efficacy of Ropinirole can be decreased when used in combination with Amineptine.
AminophenazoneThe metabolism of Aminophenazone can be decreased when combined with Ropinirole.
AminophyllineThe metabolism of Aminophylline can be decreased when combined with Ropinirole.
AmiodaroneThe metabolism of Ropinirole can be decreased when combined with Amiodarone.
AmisulprideAmisulpride may increase the sedative activities of Ropinirole.
AmitriptylineAmitriptyline may increase the sedative activities of Ropinirole.
AmitriptylineThe metabolism of Amitriptyline can be decreased when combined with Ropinirole.
AmobarbitalAmobarbital may increase the sedative activities of Ropinirole.
AmoxapineAmoxapine may increase the sedative activities of Ropinirole.
AmoxapineThe metabolism of Amoxapine can be decreased when combined with Ropinirole.
AmperozideAmperozide may increase the sedative activities of Ropinirole.
AmphetamineThe metabolism of Amphetamine can be decreased when combined with Ropinirole.
AmprenavirThe metabolism of Amprenavir can be decreased when combined with Ropinirole.
AmsacrineThe metabolism of Amsacrine can be decreased when combined with Ropinirole.
AnagrelideThe metabolism of Anagrelide can be decreased when combined with Ropinirole.
AntipyrineThe metabolism of Antipyrine can be decreased when combined with Ropinirole.
ApixabanThe metabolism of Apixaban can be decreased when combined with Ropinirole.
AprepitantThe serum concentration of Ropinirole can be increased when it is combined with Aprepitant.
AprepitantThe metabolism of Aprepitant can be decreased when combined with Ropinirole.
AprindineThe metabolism of Aprindine can be decreased when combined with Ropinirole.
ArformoterolThe metabolism of Arformoterol can be decreased when combined with Ropinirole.
AripiprazoleAripiprazole may increase the sedative activities of Ropinirole.
AripiprazoleThe serum concentration of Aripiprazole can be increased when it is combined with Ropinirole.
ArotinololRopinirole may increase the atrioventricular blocking (AV block) activities of Arotinolol.
ArtemetherThe metabolism of Artemether can be decreased when combined with Ropinirole.
ArticaineArticaine may increase the sedative activities of Ropinirole.
ASA404The metabolism of ASA404 can be decreased when combined with Ropinirole.
AsenapineAsenapine may increase the sedative activities of Ropinirole.
AsenapineThe metabolism of Asenapine can be decreased when combined with Ropinirole.
AstemizoleThe metabolism of Astemizole can be decreased when combined with Ropinirole.
AtazanavirThe metabolism of Ropinirole can be decreased when combined with Atazanavir.
AtenololRopinirole may increase the atrioventricular blocking (AV block) activities of Atenolol.
AtomoxetineThe metabolism of Ropinirole can be decreased when combined with Atomoxetine.
AV650The metabolism of AV650 can be decreased when combined with Ropinirole.
AxitinibThe metabolism of Axitinib can be decreased when combined with Ropinirole.
AzaperoneAzaperone may increase the sedative activities of Ropinirole.
AzelastineAzelastine may increase the sedative activities of Ropinirole.
AzelastineThe metabolism of Azelastine can be decreased when combined with Ropinirole.
AzithromycinThe metabolism of Ropinirole can be decreased when combined with Azithromycin.
BaclofenBaclofen may increase the sedative activities of Ropinirole.
BarbitalBarbital may increase the sedative activities of Ropinirole.
BazedoxifeneThe serum concentration of Ropinirole can be increased when it is combined with Bazedoxifene.
BefunololRopinirole may increase the atrioventricular blocking (AV block) activities of Befunolol.
BendamustineThe metabolism of Bendamustine can be decreased when combined with Ropinirole.
BenmoxinThe metabolism of Ropinirole can be decreased when combined with Benmoxin.
BenzatropineThe metabolism of Benzatropine can be decreased when combined with Ropinirole.
BenzocaineBenzocaine may increase the sedative activities of Ropinirole.
Benzyl alcoholBenzyl alcohol may increase the sedative activities of Ropinirole.
Benzyl alcoholThe metabolism of Benzyl alcohol can be decreased when combined with Ropinirole.
BepridilThe metabolism of Bepridil can be decreased when combined with Ropinirole.
BetaxololThe metabolism of Betaxolol can be decreased when combined with Ropinirole.
BevantololRopinirole may increase the atrioventricular blocking (AV block) activities of Bevantolol.
BexaroteneThe serum concentration of Ropinirole can be decreased when it is combined with Bexarotene.
BisoprololThe metabolism of Bisoprolol can be decreased when combined with Ropinirole.
BoceprevirThe metabolism of Ropinirole can be decreased when combined with Boceprevir.
BopindololRopinirole may increase the atrioventricular blocking (AV block) activities of Bopindolol.
BortezomibThe metabolism of Ropinirole can be decreased when combined with Bortezomib.
BosentanThe serum concentration of Ropinirole can be decreased when it is combined with Bosentan.
BrexpiprazoleBrexpiprazole may increase the sedative activities of Ropinirole.
BrexpiprazoleThe serum concentration of Brexpiprazole can be increased when it is combined with Ropinirole.
BrimonidineBrimonidine may increase the sedative activities of Ropinirole.
BromazepamBromazepam may increase the sedative activities of Ropinirole.
BromazepamThe metabolism of Bromazepam can be decreased when combined with Ropinirole.
BromocriptineBromocriptine may increase the vasoconstricting activities of Ropinirole.
BrompheniramineBrompheniramine may increase the sedative activities of Ropinirole.
BrompheniramineThe metabolism of Brompheniramine can be decreased when combined with Ropinirole.
BrotizolamBrotizolam may increase the sedative activities of Ropinirole.
BufuralolThe metabolism of Bufuralol can be decreased when combined with Ropinirole.
BupivacaineBupivacaine may increase the sedative activities of Ropinirole.
BupivacaineThe metabolism of Bupivacaine can be decreased when combined with Ropinirole.
BupranololRopinirole may increase the atrioventricular blocking (AV block) activities of Bupranolol.
BuprenorphineBuprenorphine may increase the sedative activities of Ropinirole.
BuprenorphineThe metabolism of Buprenorphine can be decreased when combined with Ropinirole.
BupropionThe metabolism of Bupropion can be decreased when combined with Ropinirole.
BuspironeBuspirone may increase the sedative activities of Ropinirole.
BuspironeThe metabolism of Buspirone can be decreased when combined with Ropinirole.
ButabarbitalButabarbital may increase the sedative activities of Ropinirole.
ButacaineButacaine may increase the sedative activities of Ropinirole.
ButalbitalButalbital may increase the sedative activities of Ropinirole.
ButambenButamben may increase the sedative activities of Ropinirole.
ButethalButethal may increase the sedative activities of Ropinirole.
ButorphanolButorphanol may increase the sedative activities of Ropinirole.
CabergolineCabergoline may increase the vasoconstricting activities of Ropinirole.
CaffeineThe metabolism of Ropinirole can be decreased when combined with Caffeine.
CaptoprilThe metabolism of Captopril can be decreased when combined with Ropinirole.
CarbamazepineCarbamazepine may increase the sedative activities of Ropinirole.
CarbamazepineThe metabolism of Carbamazepine can be decreased when combined with Ropinirole.
CarbinoxamineCarbinoxamine may increase the sedative activities of Ropinirole.
CarfentanilCarfentanil may increase the sedative activities of Ropinirole.
CariprazineThe metabolism of Cariprazine can be decreased when combined with Ropinirole.
CarisoprodolCarisoprodol may increase the sedative activities of Ropinirole.
CarmustineThe metabolism of Carmustine can be decreased when combined with Ropinirole.
CaroxazoneThe metabolism of Ropinirole can be decreased when combined with Caroxazone.
CarteololThe metabolism of Carteolol can be decreased when combined with Ropinirole.
CarvedilolThe metabolism of Carvedilol can be decreased when combined with Ropinirole.
CeliprololRopinirole may increase the atrioventricular blocking (AV block) activities of Celiprolol.
CephalexinThe metabolism of Cephalexin can be decreased when combined with Ropinirole.
CeritinibThe serum concentration of Ropinirole can be increased when it is combined with Ceritinib.
CetirizineCetirizine may increase the sedative activities of Ropinirole.
CevimelineThe metabolism of Cevimeline can be decreased when combined with Ropinirole.
Chloral hydrateChloral hydrate may increase the sedative activities of Ropinirole.
ChlordiazepoxideChlordiazepoxide may increase the sedative activities of Ropinirole.
ChlordiazepoxideThe metabolism of Chlordiazepoxide can be decreased when combined with Ropinirole.
ChlormezanoneChlormezanone may increase the sedative activities of Ropinirole.
ChloroprocaineChloroprocaine may increase the sedative activities of Ropinirole.
ChloroquineThe metabolism of Chloroquine can be decreased when combined with Ropinirole.
ChlorotrianiseneThe serum concentration of Ropinirole can be increased when it is combined with Chlorotrianisene.
ChlorphenamineChlorphenamine may increase the sedative activities of Ropinirole.
ChlorphenamineThe metabolism of Chlorphenamine can be decreased when combined with Ropinirole.
ChlorpromazineChlorpromazine may increase the sedative activities of Ropinirole.
ChlorpromazineThe metabolism of Chlorpromazine can be decreased when combined with Ropinirole.
ChlorprothixeneChlorprothixene may increase the sedative activities of Ropinirole.
ChlorzoxazoneChlorzoxazone may increase the sedative activities of Ropinirole.
ChlorzoxazoneThe metabolism of Chlorzoxazone can be decreased when combined with Ropinirole.
CilostazolThe metabolism of Cilostazol can be decreased when combined with Ropinirole.
CinacalcetThe metabolism of Cinacalcet can be decreased when combined with Ropinirole.
CinchocaineCinchocaine may increase the sedative activities of Ropinirole.
CinnarizineThe metabolism of Cinnarizine can be decreased when combined with Ropinirole.
CiprofloxacinThe serum concentration of Ropinirole can be increased when it is combined with Ciprofloxacin.
CisaprideThe metabolism of Cisapride can be decreased when combined with Ropinirole.
CitalopramThe metabolism of Ropinirole can be decreased when combined with Citalopram.
ClarithromycinThe metabolism of Ropinirole can be decreased when combined with Clarithromycin.
ClemastineClemastine may increase the sedative activities of Ropinirole.
ClenbuterolThe metabolism of Clenbuterol can be decreased when combined with Ropinirole.
ClevidipineThe metabolism of Clevidipine can be decreased when combined with Ropinirole.
ClidiniumClidinium may increase the sedative activities of Ropinirole.
ClobazamClobazam may increase the sedative activities of Ropinirole.
clomethiazoleclomethiazole may increase the sedative activities of Ropinirole.
ClomipramineClomipramine may increase the sedative activities of Ropinirole.
ClomipramineThe metabolism of Clomipramine can be decreased when combined with Ropinirole.
ClonazepamClonazepam may increase the sedative activities of Ropinirole.
ClonidineClonidine may increase the sedative activities of Ropinirole.
ClonidineThe metabolism of Clonidine can be decreased when combined with Ropinirole.
ClopidogrelThe metabolism of Clopidogrel can be decreased when combined with Ropinirole.
ClorazepateClorazepate may increase the sedative activities of Ropinirole.
ClotrimazoleThe metabolism of Ropinirole can be decreased when combined with Clotrimazole.
ClozapineClozapine may increase the sedative activities of Ropinirole.
ClozapineThe metabolism of Clozapine can be decreased when combined with Ropinirole.
CobicistatThe metabolism of Ropinirole can be decreased when combined with Cobicistat.
CocaineCocaine may increase the sedative activities of Ropinirole.
CodeineThe therapeutic efficacy of Codeine can be decreased when used in combination with Ropinirole.
CodeineCodeine may increase the sedative activities of Ropinirole.
ConivaptanThe serum concentration of Ropinirole can be increased when it is combined with Conivaptan.
Conjugated Equine EstrogensThe serum concentration of Ropinirole can be increased when it is combined with Conjugated Equine Estrogens.
Conjugated Equine EstrogensThe metabolism of Conjugated Equine Estrogens can be decreased when combined with Ropinirole.
CrizotinibThe metabolism of Ropinirole can be decreased when combined with Crizotinib.
CyclizineCyclizine may increase the sedative activities of Ropinirole.
CyclobenzaprineCyclobenzaprine may increase the sedative activities of Ropinirole.
CyclobenzaprineThe metabolism of Cyclobenzaprine can be decreased when combined with Ropinirole.
CyclophosphamideThe metabolism of Cyclophosphamide can be decreased when combined with Ropinirole.
CyclosporineThe metabolism of Ropinirole can be decreased when combined with Cyclosporine.
CyproheptadineCyproheptadine may increase the sedative activities of Ropinirole.
Cyproterone acetateThe serum concentration of Ropinirole can be decreased when it is combined with Cyproterone acetate.
DabrafenibThe serum concentration of Ropinirole can be decreased when it is combined with Dabrafenib.
DacarbazineThe metabolism of Dacarbazine can be decreased when combined with Ropinirole.
DantroleneDantrolene may increase the sedative activities of Ropinirole.
DapagliflozinThe metabolism of Dapagliflozin can be decreased when combined with Ropinirole.
DapiprazoleDapiprazole may increase the sedative activities of Ropinirole.
DarifenacinThe metabolism of Darifenacin can be decreased when combined with Ropinirole.
DarunavirThe metabolism of Ropinirole can be decreased when combined with Darunavir.
DasabuvirThe metabolism of Dasabuvir can be decreased when combined with Ropinirole.
DasatinibThe serum concentration of Ropinirole can be increased when it is combined with Dasatinib.
DasatinibThe metabolism of Dasatinib can be decreased when combined with Ropinirole.
DaunorubicinThe metabolism of Daunorubicin can be decreased when combined with Ropinirole.
DebrisoquinThe metabolism of Debrisoquin can be decreased when combined with Ropinirole.
DeferasiroxThe serum concentration of Ropinirole can be decreased when it is combined with Deferasirox.
DelavirdineThe metabolism of Ropinirole can be decreased when combined with Delavirdine.
deramciclanederamciclane may increase the sedative activities of Ropinirole.
DesfluraneDesflurane may increase the sedative activities of Ropinirole.
DesipramineDesipramine may increase the sedative activities of Ropinirole.
DesipramineThe metabolism of Desipramine can be decreased when combined with Ropinirole.
DesloratadineDesloratadine may increase the sedative activities of Ropinirole.
DesvenlafaxineDesvenlafaxine may decrease the antihypertensive activities of Ropinirole.
DetomidineDetomidine may increase the sedative activities of Ropinirole.
DexamethasoneThe serum concentration of Ropinirole can be decreased when it is combined with Dexamethasone.
DexbrompheniramineDexbrompheniramine may increase the sedative activities of Ropinirole.
DexfenfluramineThe metabolism of Dexfenfluramine can be decreased when combined with Ropinirole.
DexmedetomidineDexmedetomidine may increase the sedative activities of Ropinirole.
DexmethylphenidateThe metabolism of Dexmethylphenidate can be decreased when combined with Ropinirole.
DextroamphetamineThe metabolism of Dextroamphetamine can be decreased when combined with Ropinirole.
DextromethorphanThe metabolism of Dextromethorphan can be decreased when combined with Ropinirole.
DextromoramideDextromoramide may increase the sedative activities of Ropinirole.
DextropropoxypheneDextropropoxyphene may increase the sedative activities of Ropinirole.
DezocineDezocine may increase the sedative activities of Ropinirole.
DiazepamDiazepam may increase the sedative activities of Ropinirole.
DiazepamThe metabolism of Diazepam can be decreased when combined with Ropinirole.
DiclofenacThe metabolism of Diclofenac can be decreased when combined with Ropinirole.
DienestrolThe serum concentration of Ropinirole can be increased when it is combined with Dienestrol.
DiethylstilbestrolThe serum concentration of Ropinirole can be increased when it is combined with Diethylstilbestrol.
DifenoxinDifenoxin may increase the sedative activities of Ropinirole.
DihydrocodeineDihydrocodeine may increase the sedative activities of Ropinirole.
DihydrocodeineThe metabolism of Dihydrocodeine can be decreased when combined with Ropinirole.
DihydroergotamineDihydroergotamine may increase the vasoconstricting activities of Ropinirole.
DihydroetorphineDihydroetorphine may increase the sedative activities of Ropinirole.
DihydromorphineDihydromorphine may increase the sedative activities of Ropinirole.
DiltiazemThe metabolism of Ropinirole can be decreased when combined with Diltiazem.
DimenhydrinateDimenhydrinate may increase the sedative activities of Ropinirole.
DinoprostoneThe metabolism of Dinoprostone can be decreased when combined with Ropinirole.
DiphenhydramineDiphenhydramine may increase the sedative activities of Ropinirole.
DiphenhydramineThe metabolism of Diphenhydramine can be decreased when combined with Ropinirole.
DiphenoxylateDiphenoxylate may increase the sedative activities of Ropinirole.
DolasetronThe metabolism of Dolasetron can be decreased when combined with Ropinirole.
DomperidoneThe metabolism of Domperidone can be decreased when combined with Ropinirole.
DonepezilThe metabolism of Donepezil can be decreased when combined with Ropinirole.
DopamineThe metabolism of Dopamine can be decreased when combined with Ropinirole.
DoramectinDoramectin may increase the sedative activities of Ropinirole.
DosulepinThe therapeutic efficacy of Ropinirole can be decreased when used in combination with Dosulepin.
DoxazosinThe metabolism of Doxazosin can be decreased when combined with Ropinirole.
DoxepinDoxepin may increase the sedative activities of Ropinirole.
DoxepinThe metabolism of Doxepin can be decreased when combined with Ropinirole.
DoxorubicinThe metabolism of Doxorubicin can be decreased when combined with Ropinirole.
DoxycyclineThe metabolism of Ropinirole can be decreased when combined with Doxycycline.
DoxylamineDoxylamine may increase the sedative activities of Ropinirole.
DPDPEDPDPE may increase the sedative activities of Ropinirole.
DronedaroneThe metabolism of Ropinirole can be decreased when combined with Dronedarone.
DroperidolDroperidol may increase the sedative activities of Ropinirole.
DrotebanolDrotebanol may increase the sedative activities of Ropinirole.
DroxidopaRopinirole may increase the hypertensive activities of Droxidopa.
DuloxetineThe metabolism of Duloxetine can be decreased when combined with Ropinirole.
DuloxetineDuloxetine may decrease the antihypertensive activities of Ropinirole.
DyclonineDyclonine may increase the sedative activities of Ropinirole.
EcgonineEcgonine may increase the sedative activities of Ropinirole.
ECGONINE METHYL ESTERECGONINE METHYL ESTER may increase the sedative activities of Ropinirole.
EfavirenzEfavirenz may increase the sedative activities of Ropinirole.
EletriptanThe metabolism of Eletriptan can be decreased when combined with Ropinirole.
EliglustatThe metabolism of Eliglustat can be decreased when combined with Ropinirole.
EltrombopagThe metabolism of Eltrombopag can be decreased when combined with Ropinirole.
EncainideThe metabolism of Encainide can be decreased when combined with Ropinirole.
EnclomipheneThe metabolism of Enclomiphene can be decreased when combined with Ropinirole.
EnfluraneEnflurane may increase the sedative activities of Ropinirole.
EntacaponeEntacapone may increase the sedative activities of Ropinirole.
EnzalutamideThe serum concentration of Ropinirole can be decreased when it is combined with Enzalutamide.
EpinastineThe metabolism of Epinastine can be decreased when combined with Ropinirole.
Ergoloid mesylateErgoloid mesylate may increase the vasoconstricting activities of Ropinirole.
ErgonovineErgonovine may increase the vasoconstricting activities of Ropinirole.
ErgotamineThe metabolism of Ergotamine can be decreased when combined with Ropinirole.
ErgotamineErgotamine may increase the vasoconstricting activities of Ropinirole.
ErlotinibThe metabolism of Erlotinib can be decreased when combined with Ropinirole.
ErythromycinThe metabolism of Ropinirole can be decreased when combined with Erythromycin.
EscitalopramThe metabolism of Escitalopram can be decreased when combined with Ropinirole.
Eslicarbazepine acetateThe serum concentration of Ropinirole can be decreased when it is combined with Eslicarbazepine acetate.
EsmirtazapineThe therapeutic efficacy of Ropinirole can be decreased when used in combination with Esmirtazapine.
EsmirtazapineThe metabolism of Esmirtazapine can be decreased when combined with Ropinirole.
EsmololRopinirole may increase the atrioventricular blocking (AV block) activities of Esmolol.
EstazolamEstazolam may increase the sedative activities of Ropinirole.
EstradiolThe serum concentration of Ropinirole can be increased when it is combined with Estradiol.
EstradiolThe metabolism of Estradiol can be decreased when combined with Ropinirole.
EstriolThe serum concentration of Ropinirole can be increased when it is combined with Estriol.
EstroneThe serum concentration of Ropinirole can be increased when it is combined with Estrone.
EstroneThe metabolism of Estrone can be decreased when combined with Ropinirole.
Estrone sulfateThe metabolism of Estrone sulfate can be decreased when combined with Ropinirole.
EszopicloneEszopiclone may increase the sedative activities of Ropinirole.
EthanolEthanol may increase the sedative activities of Ropinirole.
EthanolThe metabolism of Ethanol can be decreased when combined with Ropinirole.
EthchlorvynolEthchlorvynol may increase the sedative activities of Ropinirole.
Ethinyl EstradiolThe serum concentration of Ropinirole can be increased when it is combined with Ethinyl Estradiol.
EthosuximideEthosuximide may increase the sedative activities of Ropinirole.
EthotoinEthotoin may increase the sedative activities of Ropinirole.
Ethyl carbamateEthyl carbamate may increase the sedative activities of Ropinirole.
Ethyl loflazepateEthyl loflazepate may increase the sedative activities of Ropinirole.
EthylmorphineEthylmorphine may increase the sedative activities of Ropinirole.
EthylmorphineThe metabolism of Ethylmorphine can be decreased when combined with Ropinirole.
EtidocaineEtidocaine may increase the sedative activities of Ropinirole.
EtifoxineEtifoxine may increase the sedative activities of Ropinirole.
EtizolamEtizolam may increase the sedative activities of Ropinirole.
EtomidateEtomidate may increase the sedative activities of Ropinirole.
EtoposideThe metabolism of Etoposide can be decreased when combined with Ropinirole.
EtoricoxibThe metabolism of Etoricoxib can be decreased when combined with Ropinirole.
EtorphineEtorphine may increase the sedative activities of Ropinirole.
EtravirineThe serum concentration of Ropinirole can be decreased when it is combined with Etravirine.
EzogabineEzogabine may increase the sedative activities of Ropinirole.
FelbamateFelbamate may increase the sedative activities of Ropinirole.
FencamfamineFencamfamine may increase the sedative activities of Ropinirole.
FentanylFentanyl may increase the sedative activities of Ropinirole.
FesoterodineThe serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Ropinirole.
FexofenadineFexofenadine may increase the sedative activities of Ropinirole.
FingolimodThe metabolism of Fingolimod can be decreased when combined with Ropinirole.
FlecainideThe metabolism of Flecainide can be decreased when combined with Ropinirole.
FlibanserinFlibanserin may increase the sedative activities of Ropinirole.
FluconazoleThe metabolism of Ropinirole can be decreased when combined with Fluconazole.
FludiazepamFludiazepam may increase the sedative activities of Ropinirole.
FlunarizineFlunarizine may increase the sedative activities of Ropinirole.
FlunarizineThe metabolism of Flunarizine can be decreased when combined with Ropinirole.
FlunitrazepamFlunitrazepam may increase the sedative activities of Ropinirole.
FlunitrazepamThe metabolism of Flunitrazepam can be decreased when combined with Ropinirole.
FluorouracilThe metabolism of Fluorouracil can be decreased when combined with Ropinirole.
FluoxetineThe metabolism of Fluoxetine can be decreased when combined with Ropinirole.
FlupentixolFlupentixol may increase the sedative activities of Ropinirole.
FluphenazineFluphenazine may increase the sedative activities of Ropinirole.
FluphenazineThe metabolism of Fluphenazine can be decreased when combined with Ropinirole.
FlurazepamFlurazepam may increase the sedative activities of Ropinirole.
FluspirileneFluspirilene may increase the sedative activities of Ropinirole.
FlutamideThe metabolism of Flutamide can be decreased when combined with Ropinirole.
Fluticasone PropionateFluticasone Propionate may increase the sedative activities of Ropinirole.
FluvastatinThe metabolism of Fluvastatin can be decreased when combined with Ropinirole.
FluvoxamineFluvoxamine may increase the sedative activities of Ropinirole.
FluvoxamineThe metabolism of Fluvoxamine can be decreased when combined with Ropinirole.
FormoterolThe metabolism of Formoterol can be decreased when combined with Ropinirole.
FosamprenavirThe metabolism of Ropinirole can be decreased when combined with Fosamprenavir.
FosaprepitantThe serum concentration of Ropinirole can be increased when it is combined with Fosaprepitant.
FosphenytoinFosphenytoin may increase the sedative activities of Ropinirole.
FospropofolFospropofol may increase the sedative activities of Ropinirole.
FrovatriptanThe metabolism of Frovatriptan can be decreased when combined with Ropinirole.
FurazolidoneThe metabolism of Ropinirole can be decreased when combined with Furazolidone.
Fusidic AcidThe serum concentration of Ropinirole can be increased when it is combined with Fusidic Acid.
GabapentinGabapentin may increase the sedative activities of Ropinirole.
gabapentin enacarbilgabapentin enacarbil may increase the sedative activities of Ropinirole.
GalantamineThe metabolism of Galantamine can be decreased when combined with Ropinirole.
Gamma Hydroxybutyric AcidGamma Hydroxybutyric Acid may increase the sedative activities of Ropinirole.
GefitinibThe metabolism of Gefitinib can be decreased when combined with Ropinirole.
GenisteinThe serum concentration of Ropinirole can be increased when it is combined with Genistein.
GenisteinThe metabolism of Genistein can be decreased when combined with Ropinirole.
GlutethimideGlutethimide may increase the sedative activities of Ropinirole.
GranisetronThe metabolism of Granisetron can be decreased when combined with Ropinirole.
GrepafloxacinThe metabolism of Grepafloxacin can be decreased when combined with Ropinirole.
GuanabenzThe metabolism of Guanabenz can be decreased when combined with Ropinirole.
GuanfacineGuanfacine may increase the sedative activities of Ropinirole.
HalazepamHalazepam may increase the sedative activities of Ropinirole.
HalofantrineThe metabolism of Halofantrine can be decreased when combined with Ropinirole.
HaloperidolHaloperidol may increase the sedative activities of Ropinirole.
HaloperidolThe metabolism of Haloperidol can be decreased when combined with Ropinirole.
HalothaneHalothane may increase the sedative activities of Ropinirole.
HalothaneThe metabolism of Halothane can be decreased when combined with Ropinirole.
HeroinHeroin may increase the sedative activities of Ropinirole.
HesperetinThe metabolism of Hesperetin can be decreased when combined with Ropinirole.
HexestrolThe serum concentration of Ropinirole can be increased when it is combined with Hexestrol.
HexobarbitalHexobarbital may increase the sedative activities of Ropinirole.
HexobarbitalThe metabolism of Hexobarbital can be decreased when combined with Ropinirole.
HydracarbazineThe metabolism of Ropinirole can be decreased when combined with Hydracarbazine.
HydrocodoneHydrocodone may increase the sedative activities of Ropinirole.
HydrocodoneThe metabolism of Hydrocodone can be decreased when combined with Ropinirole.
HydromorphoneHydromorphone may increase the sedative activities of Ropinirole.
HydromorphoneThe metabolism of Hydromorphone can be decreased when combined with Ropinirole.
HydroxyzineHydroxyzine may increase the sedative activities of Ropinirole.
IbrutinibThe metabolism of Ibrutinib can be decreased when combined with Ropinirole.
IdarubicinThe metabolism of Idarubicin can be decreased when combined with Ropinirole.
IdelalisibThe serum concentration of Ropinirole can be increased when it is combined with Idelalisib.
IloperidoneIloperidone may increase the sedative activities of Ropinirole.
IloperidoneThe metabolism of Iloperidone can be decreased when combined with Ropinirole.
ImatinibThe metabolism of Ropinirole can be decreased when combined with Imatinib.
ImipramineImipramine may increase the sedative activities of Ropinirole.
ImipramineThe metabolism of Imipramine can be decreased when combined with Ropinirole.
ImiquimodThe metabolism of Imiquimod can be decreased when combined with Ropinirole.
IndenololRopinirole may increase the atrioventricular blocking (AV block) activities of Indenolol.
IndinavirThe metabolism of Ropinirole can be decreased when combined with Indinavir.
Ipratropium bromideThe metabolism of Ipratropium bromide can be decreased when combined with Ropinirole.
IproclozideThe metabolism of Ropinirole can be decreased when combined with Iproclozide.
IproniazidThe metabolism of Ropinirole can be decreased when combined with Iproniazid.
IsavuconazoniumThe metabolism of Ropinirole can be decreased when combined with Isavuconazonium.
IsocarboxazidThe metabolism of Ropinirole can be decreased when combined with Isocarboxazid.
IsofluraneIsoflurane may increase the sedative activities of Ropinirole.
IsradipineThe metabolism of Ropinirole can be decreased when combined with Isradipine.
ItraconazoleThe metabolism of Ropinirole can be decreased when combined with Itraconazole.
IvacaftorThe serum concentration of Ropinirole can be increased when it is combined with Ivacaftor.
IxazomibThe metabolism of Ixazomib can be decreased when combined with Ropinirole.
KetamineKetamine may increase the sedative activities of Ropinirole.
KetazolamKetazolam may increase the sedative activities of Ropinirole.
KetobemidoneKetobemidone may increase the sedative activities of Ropinirole.
KetoconazoleThe metabolism of Ropinirole can be decreased when combined with Ketoconazole.
LabetalolThe metabolism of Labetalol can be decreased when combined with Ropinirole.
LamotrigineLamotrigine may increase the sedative activities of Ropinirole.
LeflunomideThe metabolism of Leflunomide can be decreased when combined with Ropinirole.
LevetiracetamLevetiracetam may increase the sedative activities of Ropinirole.
LevobupivacaineLevobupivacaine may increase the sedative activities of Ropinirole.
LevobupivacaineThe metabolism of Levobupivacaine can be decreased when combined with Ropinirole.
LevocabastineLevocabastine may increase the sedative activities of Ropinirole.
LevocetirizineLevocetirizine may increase the sedative activities of Ropinirole.
LevodopaLevodopa may increase the sedative activities of Ropinirole.
LevodopaThe metabolism of Levodopa can be decreased when combined with Ropinirole.
Levomethadyl AcetateLevomethadyl Acetate may increase the sedative activities of Ropinirole.
LevomilnacipranThe metabolism of Levomilnacipran can be decreased when combined with Ropinirole.
LevomilnacipranLevomilnacipran may decrease the antihypertensive activities of Ropinirole.
LevorphanolLevorphanol may increase the sedative activities of Ropinirole.
LidocaineLidocaine may increase the sedative activities of Ropinirole.
LidocaineThe metabolism of Lidocaine can be decreased when combined with Ropinirole.
LisurideThe metabolism of Lisuride can be decreased when combined with Ropinirole.
LithiumLithium may increase the sedative activities of Ropinirole.
LofentanilLofentanil may increase the sedative activities of Ropinirole.
LomefloxacinThe metabolism of Lomefloxacin can be decreased when combined with Ropinirole.
LomustineThe metabolism of Lomustine can be decreased when combined with Ropinirole.
LoperamideThe metabolism of Loperamide can be decreased when combined with Ropinirole.
LopinavirThe metabolism of Ropinirole can be decreased when combined with Lopinavir.
LoratadineLoratadine may increase the sedative activities of Ropinirole.
LoratadineThe metabolism of Loratadine can be decreased when combined with Ropinirole.
LorazepamLorazepam may increase the sedative activities of Ropinirole.
LorcaserinThe metabolism of Lorcaserin can be decreased when combined with Ropinirole.
LovastatinThe metabolism of Ropinirole can be decreased when combined with Lovastatin.
LoxapineLoxapine may increase the sedative activities of Ropinirole.
Lu AA21004Lu AA21004 may increase the sedative activities of Ropinirole.
LuliconazoleThe serum concentration of Ropinirole can be increased when it is combined with Luliconazole.
LumiracoxibThe metabolism of Lumiracoxib can be decreased when combined with Ropinirole.
LurasidoneLurasidone may increase the sedative activities of Ropinirole.
Magnesium SulfateMagnesium Sulfate may increase the sedative activities of Ropinirole.
MalathionThe metabolism of Malathion can be decreased when combined with Ropinirole.
MaprotilineMaprotiline may increase the sedative activities of Ropinirole.
MaprotilineThe metabolism of Maprotiline can be decreased when combined with Ropinirole.
MebanazineThe metabolism of Ropinirole can be decreased when combined with Mebanazine.
MeclizineMeclizine may increase the sedative activities of Ropinirole.
MedetomidineMedetomidine may increase the sedative activities of Ropinirole.
MelatoninMelatonin may increase the sedative activities of Ropinirole.
MelatoninThe metabolism of Melatonin can be decreased when combined with Ropinirole.
MelperoneMelperone may increase the sedative activities of Ropinirole.
MenadioneThe metabolism of Menadione can be decreased when combined with Ropinirole.
MephenytoinThe metabolism of Mephenytoin can be decreased when combined with Ropinirole.
MepivacaineMepivacaine may increase the sedative activities of Ropinirole.
MeprobamateMeprobamate may increase the sedative activities of Ropinirole.
MequitazineThe metabolism of Mequitazine can be decreased when combined with Ropinirole.
MesoridazineMesoridazine may increase the sedative activities of Ropinirole.
MesoridazineThe metabolism of Mesoridazine can be decreased when combined with Ropinirole.
MestranolThe serum concentration of Ropinirole can be increased when it is combined with Mestranol.
MetaxaloneMetaxalone may increase the sedative activities of Ropinirole.
MethadoneMethadone may increase the sedative activities of Ropinirole.
MethadoneThe metabolism of Methadone can be decreased when combined with Ropinirole.
Methadyl AcetateMethadyl Acetate may increase the sedative activities of Ropinirole.
MethamphetamineThe metabolism of Methamphetamine can be decreased when combined with Ropinirole.
MethapyrileneMethapyrilene may increase the sedative activities of Ropinirole.
MethaqualoneMethaqualone may increase the sedative activities of Ropinirole.
MethocarbamolMethocarbamol may increase the sedative activities of Ropinirole.
MethohexitalMethohexital may increase the sedative activities of Ropinirole.
MethotrimeprazineMethotrimeprazine may increase the sedative activities of Ropinirole.
MethotrimeprazineThe metabolism of Methotrimeprazine can be decreased when combined with Ropinirole.
MethoxyfluraneMethoxyflurane may increase the sedative activities of Ropinirole.
MethoxyfluraneThe metabolism of Methoxyflurane can be decreased when combined with Ropinirole.
MethsuximideMethsuximide may increase the sedative activities of Ropinirole.
Methylene blueThe metabolism of Ropinirole can be decreased when combined with Methylene blue.
MethylphenidateThe metabolism of Methylphenidate can be decreased when combined with Ropinirole.
MethylphenobarbitalMethylphenobarbital may increase the sedative activities of Ropinirole.
MethyprylonThe metabolism of Methyprylon can be decreased when combined with Ropinirole.
MetoclopramideThe metabolism of Metoclopramide can be decreased when combined with Ropinirole.
MetoprololThe metabolism of Metoprolol can be decreased when combined with Ropinirole.
MexiletineThe metabolism of Mexiletine can be decreased when combined with Ropinirole.
MianserinThe therapeutic efficacy of Ropinirole can be decreased when used in combination with Mianserin.
MianserinThe metabolism of Mianserin can be decreased when combined with Ropinirole.
MidazolamMidazolam may increase the sedative activities of Ropinirole.
MifepristoneThe metabolism of Ropinirole can be decreased when combined with Mifepristone.
MilnacipranMilnacipran may decrease the antihypertensive activities of Ropinirole.
MinaprineThe metabolism of Minaprine can be decreased when combined with Ropinirole.
MirabegronThe metabolism of Mirabegron can be decreased when combined with Ropinirole.
MirtazapineMirtazapine may increase the sedative activities of Ropinirole.
MirtazapineThe metabolism of Mirtazapine can be decreased when combined with Ropinirole.
MitotaneThe serum concentration of Ropinirole can be decreased when it is combined with Mitotane.
MoclobemideThe metabolism of Moclobemide can be decreased when combined with Ropinirole.
ModafinilThe serum concentration of Ropinirole can be decreased when it is combined with Modafinil.
MolindoneMolindone may increase the sedative activities of Ropinirole.
MorphineMorphine may increase the sedative activities of Ropinirole.
MorphineThe metabolism of Morphine can be decreased when combined with Ropinirole.
muraglitazarThe metabolism of muraglitazar can be decreased when combined with Ropinirole.
NabiloneNabilone may increase the sedative activities of Ropinirole.
NabumetoneThe metabolism of Nabumetone can be decreased when combined with Ropinirole.
NadololRopinirole may increase the atrioventricular blocking (AV block) activities of Nadolol.
NafcillinThe serum concentration of Ropinirole can be decreased when it is combined with Nafcillin.
NalbuphineNalbuphine may increase the sedative activities of Ropinirole.
NaproxenThe metabolism of Naproxen can be decreased when combined with Ropinirole.
NateglinideThe metabolism of Nateglinide can be decreased when combined with Ropinirole.
NebivololThe serum concentration of Nebivolol can be increased when it is combined with Ropinirole.
NefazodoneThe metabolism of Ropinirole can be decreased when combined with Nefazodone.
NelfinavirThe metabolism of Ropinirole can be decreased when combined with Nelfinavir.
NetupitantThe serum concentration of Ropinirole can be increased when it is combined with Netupitant.
NetupitantThe metabolism of Netupitant can be decreased when combined with Ropinirole.
NevirapineThe metabolism of Ropinirole can be decreased when combined with Nevirapine.
NialamideThe metabolism of Ropinirole can be decreased when combined with Nialamide.
NicardipineThe metabolism of Nicardipine can be decreased when combined with Ropinirole.
NicergolineThe metabolism of Nicergoline can be decreased when combined with Ropinirole.
NicotineThe metabolism of Nicotine can be decreased when combined with Ropinirole.
NifedipineThe metabolism of Nifedipine can be decreased when combined with Ropinirole.
NilotinibThe metabolism of Ropinirole can be decreased when combined with Nilotinib.
NitrazepamNitrazepam may increase the sedative activities of Ropinirole.
Nitric OxideThe metabolism of Nitric Oxide can be decreased when combined with Ropinirole.
NitrofuralThe metabolism of Nitrofural can be decreased when combined with Ropinirole.
Nitrous oxideNitrous oxide may increase the sedative activities of Ropinirole.
NormethadoneNormethadone may increase the sedative activities of Ropinirole.
NortriptylineNortriptyline may increase the sedative activities of Ropinirole.
NortriptylineThe metabolism of Nortriptyline can be decreased when combined with Ropinirole.
OctamoxinThe metabolism of Ropinirole can be decreased when combined with Octamoxin.
OlanzapineOlanzapine may increase the sedative activities of Ropinirole.
OlanzapineThe metabolism of Olanzapine can be decreased when combined with Ropinirole.
OlaparibThe metabolism of Ropinirole can be decreased when combined with Olaparib.
OlopatadineOlopatadine may increase the sedative activities of Ropinirole.
OmeprazoleThe metabolism of Omeprazole can be decreased when combined with Ropinirole.
OndansetronOndansetron may increase the sedative activities of Ropinirole.
OndansetronThe metabolism of Ondansetron can be decreased when combined with Ropinirole.
OpiumOpium may increase the sedative activities of Ropinirole.
OrphenadrineOrphenadrine may increase the sedative activities of Ropinirole.
OsanetantOsanetant may increase the sedative activities of Ropinirole.
OsimertinibThe serum concentration of Ropinirole can be increased when it is combined with Osimertinib.
OxaliplatinThe metabolism of Oxaliplatin can be decreased when combined with Ropinirole.
OxazepamOxazepam may increase the sedative activities of Ropinirole.
OxprenololOxprenolol may increase the sedative activities of Ropinirole.
OxprenololRopinirole may increase the atrioventricular blocking (AV block) activities of Oxprenolol.
OxtriphyllineThe metabolism of Oxtriphylline can be decreased when combined with Ropinirole.
OxybuprocaineOxybuprocaine may increase the sedative activities of Ropinirole.
OxycodoneOxycodone may increase the sedative activities of Ropinirole.
OxycodoneThe metabolism of Oxycodone can be decreased when combined with Ropinirole.
OxymorphoneOxymorphone may increase the sedative activities of Ropinirole.
OxymorphoneThe metabolism of Oxymorphone can be decreased when combined with Ropinirole.
PalbociclibThe serum concentration of Ropinirole can be increased when it is combined with Palbociclib.
PaliperidonePaliperidone may increase the sedative activities of Ropinirole.
PalonosetronThe metabolism of Palonosetron can be decreased when combined with Ropinirole.
PantoprazoleThe metabolism of Pantoprazole can be decreased when combined with Ropinirole.
ParaldehydeParaldehyde may increase the sedative activities of Ropinirole.
PargylineThe metabolism of Ropinirole can be decreased when combined with Pargyline.
ParoxetineThe metabolism of Paroxetine can be decreased when combined with Ropinirole.
PazopanibThe metabolism of Pazopanib can be decreased when combined with Ropinirole.
Peginterferon alfa-2bThe serum concentration of Ropinirole can be increased when it is combined with Peginterferon alfa-2b.
PenbutololRopinirole may increase the atrioventricular blocking (AV block) activities of Penbutolol.
PentamidineThe metabolism of Pentamidine can be decreased when combined with Ropinirole.
PentazocinePentazocine may increase the sedative activities of Ropinirole.
PentobarbitalPentobarbital may increase the sedative activities of Ropinirole.
PentoxifyllineThe metabolism of Pentoxifylline can be decreased when combined with Ropinirole.
PerampanelPerampanel may increase the sedative activities of Ropinirole.
PerhexilineThe metabolism of Perhexiline can be decreased when combined with Ropinirole.
PerospironePerospirone may increase the sedative activities of Ropinirole.
PerphenazinePerphenazine may increase the sedative activities of Ropinirole.
PerphenazineThe metabolism of Perphenazine can be decreased when combined with Ropinirole.
PethidinePethidine may increase the sedative activities of Ropinirole.
PethidineThe metabolism of Pethidine can be decreased when combined with Ropinirole.
PhenacetinThe metabolism of Phenacetin can be decreased when combined with Ropinirole.
PhenelzineThe metabolism of Ropinirole can be decreased when combined with Phenelzine.
PhenforminThe metabolism of Phenformin can be decreased when combined with Ropinirole.
PheniprazineThe metabolism of Ropinirole can be decreased when combined with Pheniprazine.
PhenobarbitalPhenobarbital may increase the sedative activities of Ropinirole.
PhenoxyethanolPhenoxyethanol may increase the sedative activities of Ropinirole.
PhenoxypropazineThe metabolism of Ropinirole can be decreased when combined with Phenoxypropazine.
PhenytoinPhenytoin may increase the sedative activities of Ropinirole.
PimozidePimozide may increase the sedative activities of Ropinirole.
PimozideThe metabolism of Pimozide can be decreased when combined with Ropinirole.
PindololThe metabolism of Pindolol can be decreased when combined with Ropinirole.
PipamperonePipamperone may increase the sedative activities of Ropinirole.
PiperazineThe metabolism of Piperazine can be decreased when combined with Ropinirole.
PipotiazinePipotiazine may increase the sedative activities of Ropinirole.
PipotiazineThe metabolism of Pipotiazine can be decreased when combined with Ropinirole.
PirfenidoneThe serum concentration of Pirfenidone can be increased when it is combined with Ropinirole.
PirlindoleThe metabolism of Ropinirole can be decreased when combined with Pirlindole.
PivhydrazineThe metabolism of Ropinirole can be decreased when combined with Pivhydrazine.
PizotifenPizotifen may increase the sedative activities of Ropinirole.
Polyestradiol phosphateThe serum concentration of Ropinirole can be increased when it is combined with Polyestradiol phosphate.
PomalidomidePomalidomide may increase the sedative activities of Ropinirole.
PomalidomideThe metabolism of Pomalidomide can be decreased when combined with Ropinirole.
PonatinibThe metabolism of Ponatinib can be decreased when combined with Ropinirole.
PosaconazoleThe metabolism of Ropinirole can be decreased when combined with Posaconazole.
PractololRopinirole may increase the atrioventricular blocking (AV block) activities of Practolol.
PramocainePramocaine may increase the sedative activities of Ropinirole.
PrazepamPrazepam may increase the sedative activities of Ropinirole.
PraziquantelThe metabolism of Praziquantel can be decreased when combined with Ropinirole.
PregabalinPregabalin may increase the sedative activities of Ropinirole.
PrilocainePrilocaine may increase the sedative activities of Ropinirole.
PrimaquineThe metabolism of Primaquine can be decreased when combined with Ropinirole.
PrimidonePrimidone may increase the sedative activities of Ropinirole.
ProcainamideThe metabolism of Procainamide can be decreased when combined with Ropinirole.
ProcaineProcaine may increase the sedative activities of Ropinirole.
ProchlorperazineProchlorperazine may increase the sedative activities of Ropinirole.
ProchlorperazineThe metabolism of Prochlorperazine can be decreased when combined with Ropinirole.
ProgesteroneThe metabolism of Progesterone can be decreased when combined with Ropinirole.
ProguanilThe metabolism of Proguanil can be decreased when combined with Ropinirole.
PromazinePromazine may increase the sedative activities of Ropinirole.
PromazineThe metabolism of Promazine can be decreased when combined with Ropinirole.
PromethazinePromethazine may increase the sedative activities of Ropinirole.
PromethazineThe metabolism of Promethazine can be decreased when combined with Ropinirole.
PropafenoneThe serum concentration of Ropinirole can be increased when it is combined with Propafenone.
PropafenoneThe metabolism of Propafenone can be decreased when combined with Ropinirole.
ProparacaineProparacaine may increase the sedative activities of Ropinirole.
PropofolPropofol may increase the sedative activities of Ropinirole.
PropofolThe metabolism of Propofol can be decreased when combined with Ropinirole.
PropoxycainePropoxycaine may increase the sedative activities of Ropinirole.
PropranololThe metabolism of Propranolol can be decreased when combined with Ropinirole.
ProtriptylineProtriptyline may increase the sedative activities of Ropinirole.
ProtriptylineThe metabolism of Protriptyline can be decreased when combined with Ropinirole.
PSD502PSD502 may increase the sedative activities of Ropinirole.
PseudoephedrineThe metabolism of Pseudoephedrine can be decreased when combined with Ropinirole.
PyrazinamideThe metabolism of Pyrazinamide can be decreased when combined with Ropinirole.
QuazepamQuazepam may increase the sedative activities of Ropinirole.
QuetiapineQuetiapine may increase the sedative activities of Ropinirole.
QuetiapineThe metabolism of Quetiapine can be decreased when combined with Ropinirole.
QuinestrolThe serum concentration of Ropinirole can be increased when it is combined with Quinestrol.
QuinineThe metabolism of Quinine can be decreased when combined with Ropinirole.
RamelteonRamelteon may increase the sedative activities of Ropinirole.
RamelteonThe metabolism of Ramelteon can be decreased when combined with Ropinirole.
RanitidineThe metabolism of Ranitidine can be decreased when combined with Ropinirole.
RanolazineThe metabolism of Ropinirole can be decreased when combined with Ranolazine.
RasagilineThe metabolism of Rasagiline can be decreased when combined with Ropinirole.
RemifentanilRemifentanil may increase the sedative activities of Ropinirole.
RemoxiprideRemoxipride may increase the sedative activities of Ropinirole.
RemoxiprideThe metabolism of Remoxipride can be decreased when combined with Ropinirole.
repinotanThe metabolism of repinotan can be decreased when combined with Ropinirole.
ReserpineReserpine may increase the sedative activities of Ropinirole.
ResveratrolThe metabolism of Resveratrol can be decreased when combined with Ropinirole.
RifabutinThe metabolism of Ropinirole can be increased when combined with Rifabutin.
RifampicinThe metabolism of Ropinirole can be increased when combined with Rifampicin.
RifapentineThe metabolism of Ropinirole can be increased when combined with Rifapentine.
RiluzoleThe metabolism of Riluzole can be decreased when combined with Ropinirole.
RisperidoneRisperidone may increase the sedative activities of Ropinirole.
RisperidoneThe metabolism of Risperidone can be decreased when combined with Ropinirole.
RitonavirThe metabolism of Ropinirole can be decreased when combined with Ritonavir.
RizatriptanThe metabolism of Rizatriptan can be decreased when combined with Ropinirole.
RofecoxibThe metabolism of Rofecoxib can be decreased when combined with Ropinirole.
RomifidineRomifidine may increase the sedative activities of Ropinirole.
RopivacaineRopivacaine may increase the sedative activities of Ropinirole.
RopivacaineThe metabolism of Ropivacaine can be decreased when combined with Ropinirole.
RotigotineThe metabolism of Rotigotine can be decreased when combined with Ropinirole.
S-EthylisothioureaS-Ethylisothiourea may increase the sedative activities of Ropinirole.
SafrazineThe metabolism of Ropinirole can be decreased when combined with Safrazine.
SaquinavirThe metabolism of Ropinirole can be decreased when combined with Saquinavir.
ScopolamineScopolamine may increase the sedative activities of Ropinirole.
SecobarbitalSecobarbital may increase the sedative activities of Ropinirole.
SelegilineThe metabolism of Selegiline can be decreased when combined with Ropinirole.
SertindoleSertindole may increase the sedative activities of Ropinirole.
SertindoleThe metabolism of Sertindole can be decreased when combined with Ropinirole.
SertralineThe metabolism of Sertraline can be decreased when combined with Ropinirole.
SevofluraneSevoflurane may increase the sedative activities of Ropinirole.
SildenafilThe metabolism of Ropinirole can be decreased when combined with Sildenafil.
SiltuximabThe serum concentration of Ropinirole can be decreased when it is combined with Siltuximab.
SimeprevirThe serum concentration of Ropinirole can be increased when it is combined with Simeprevir.
SimvastatinThe metabolism of Simvastatin can be decreased when combined with Ropinirole.
Sodium oxybateSodium oxybate may increase the sedative activities of Ropinirole.
SotalolRopinirole may increase the atrioventricular blocking (AV block) activities of Sotalol.
SparteineThe metabolism of Sparteine can be decreased when combined with Ropinirole.
St. John's WortThe serum concentration of Ropinirole can be decreased when it is combined with St. John's Wort.
StiripentolStiripentol may increase the sedative activities of Ropinirole.
SufentanilSufentanil may increase the sedative activities of Ropinirole.
SulfisoxazoleThe metabolism of Ropinirole can be decreased when combined with Sulfisoxazole.
SulpirideSulpiride may increase the sedative activities of Ropinirole.
SulpirideThe therapeutic efficacy of Sulpiride can be decreased when used in combination with Ropinirole.
SuvorexantSuvorexant may increase the sedative activities of Ropinirole.
Synthetic Conjugated Estrogens, AThe serum concentration of Ropinirole can be increased when it is combined with Synthetic Conjugated Estrogens, A.
Synthetic Conjugated Estrogens, BThe serum concentration of Ropinirole can be increased when it is combined with Synthetic Conjugated Estrogens, B.
TacrineThe metabolism of Tacrine can be decreased when combined with Ropinirole.
TamoxifenThe metabolism of Tamoxifen can be decreased when combined with Ropinirole.
TamsulosinThe metabolism of Tamsulosin can be decreased when combined with Ropinirole.
TapentadolTapentadol may increase the sedative activities of Ropinirole.
TapentadolThe metabolism of Tapentadol can be decreased when combined with Ropinirole.
TasimelteonTasimelteon may increase the sedative activities of Ropinirole.
TegaserodThe metabolism of Tegaserod can be decreased when combined with Ropinirole.
TelaprevirThe metabolism of Ropinirole can be decreased when combined with Telaprevir.
TelithromycinThe metabolism of Ropinirole can be decreased when combined with Telithromycin.
TemafloxacinThe metabolism of Temafloxacin can be decreased when combined with Ropinirole.
TemazepamTemazepam may increase the sedative activities of Ropinirole.
TenofovirThe metabolism of Ropinirole can be decreased when combined with Tenofovir.
TerbinafineThe metabolism of Terbinafine can be decreased when combined with Ropinirole.
TerfenadineThe metabolism of Terfenadine can be decreased when combined with Ropinirole.
TeriflunomideThe serum concentration of Ropinirole can be decreased when it is combined with Teriflunomide.
TesmilifeneThe metabolism of Tesmilifene can be decreased when combined with Ropinirole.
TetrabenazineTetrabenazine may increase the sedative activities of Ropinirole.
TetrabenazineThe metabolism of Tetrabenazine can be decreased when combined with Ropinirole.
TetracaineTetracaine may increase the sedative activities of Ropinirole.
TetrodotoxinTetrodotoxin may increase the sedative activities of Ropinirole.
ThalidomideThalidomide may increase the sedative activities of Ropinirole.
ThalidomideThe metabolism of Thalidomide can be decreased when combined with Ropinirole.
TheobromineThe metabolism of Theobromine can be decreased when combined with Ropinirole.
TheophyllineThe metabolism of Theophylline can be decreased when combined with Ropinirole.
ThiabendazoleThe metabolism of Thiabendazole can be decreased when combined with Ropinirole.
ThiamylalThiamylal may increase the sedative activities of Ropinirole.
ThiopentalThiopental may increase the sedative activities of Ropinirole.
ThioridazineThioridazine may increase the sedative activities of Ropinirole.
ThioridazineThe serum concentration of Thioridazine can be increased when it is combined with Ropinirole.
ThiothixeneThiothixene may increase the sedative activities of Ropinirole.
ThiothixeneThe metabolism of Thiothixene can be decreased when combined with Ropinirole.
TiagabineTiagabine may increase the sedative activities of Ropinirole.
TianeptineThe therapeutic efficacy of Ropinirole can be decreased when used in combination with Tianeptine.
TiboloneThe serum concentration of Ropinirole can be increased when it is combined with Tibolone.
TiclopidineThe metabolism of Ropinirole can be decreased when combined with Ticlopidine.
TiletamineTiletamine may increase the sedative activities of Ropinirole.
TimololThe metabolism of Timolol can be decreased when combined with Ropinirole.
TiotropiumThe metabolism of Tiotropium can be decreased when combined with Ropinirole.
TipranavirThe metabolism of Tipranavir can be decreased when combined with Ropinirole.
TizanidineTizanidine may increase the sedative activities of Ropinirole.
TizanidineThe serum concentration of Tizanidine can be increased when it is combined with Ropinirole.
TocilizumabThe serum concentration of Ropinirole can be decreased when it is combined with Tocilizumab.
TolcaponeTolcapone may increase the sedative activities of Ropinirole.
ToloxatoneThe metabolism of Ropinirole can be decreased when combined with Toloxatone.
TolterodineThe metabolism of Tolterodine can be decreased when combined with Ropinirole.
TopiramateTopiramate may increase the sedative activities of Ropinirole.
ToremifeneThe metabolism of Toremifene can be decreased when combined with Ropinirole.
TrabectedinThe metabolism of Trabectedin can be decreased when combined with Ropinirole.
TramadolTramadol may increase the sedative activities of Ropinirole.
TramadolThe therapeutic efficacy of Tramadol can be decreased when used in combination with Ropinirole.
Trans-2-PhenylcyclopropylamineThe metabolism of Ropinirole can be decreased when combined with Trans-2-Phenylcyclopropylamine.
TranylcypromineThe metabolism of Ropinirole can be decreased when combined with Tranylcypromine.
TrazodoneTrazodone may increase the sedative activities of Ropinirole.
TrazodoneThe metabolism of Trazodone can be decreased when combined with Ropinirole.
TriamtereneThe metabolism of Triamterene can be decreased when combined with Ropinirole.
TriazolamTriazolam may increase the sedative activities of Ropinirole.
TrifluoperazineTrifluoperazine may increase the sedative activities of Ropinirole.
TrifluoperazineThe metabolism of Trifluoperazine can be decreased when combined with Ropinirole.
TriflupromazineTriflupromazine may increase the sedative activities of Ropinirole.
TrimipramineTrimipramine may increase the sedative activities of Ropinirole.
TrimipramineThe metabolism of Trimipramine can be decreased when combined with Ropinirole.
TriprolidineTriprolidine may increase the sedative activities of Ropinirole.
UlipristalThe metabolism of Ulipristal can be decreased when combined with Ropinirole.
UmeclidiniumThe metabolism of Umeclidinium can be decreased when combined with Ropinirole.
Valproic AcidValproic Acid may increase the sedative activities of Ropinirole.
VemurafenibThe serum concentration of Ropinirole can be increased when it is combined with Vemurafenib.
VenlafaxineThe metabolism of Ropinirole can be decreased when combined with Venlafaxine.
VerapamilThe metabolism of Ropinirole can be decreased when combined with Verapamil.
VigabatrinVigabatrin may increase the sedative activities of Ropinirole.
VilazodoneThe metabolism of Vilazodone can be decreased when combined with Ropinirole.
VinblastineThe metabolism of Vinblastine can be decreased when combined with Ropinirole.
VinorelbineThe metabolism of Vinorelbine can be decreased when combined with Ropinirole.
VoriconazoleThe metabolism of Ropinirole can be decreased when combined with Voriconazole.
VortioxetineVortioxetine may increase the sedative activities of Ropinirole.
VortioxetineThe metabolism of Vortioxetine can be decreased when combined with Ropinirole.
WarfarinThe metabolism of Warfarin can be decreased when combined with Ropinirole.
XylazineXylazine may increase the sedative activities of Ropinirole.
YohimbineThe metabolism of Yohimbine can be decreased when combined with Ropinirole.
ZalcitabineThe metabolism of Zalcitabine can be decreased when combined with Ropinirole.
ZaleplonZaleplon may increase the sedative activities of Ropinirole.
ZeranolThe serum concentration of Ropinirole can be increased when it is combined with Zeranol.
ZiconotideZiconotide may increase the sedative activities of Ropinirole.
ZileutonThe metabolism of Zileuton can be decreased when combined with Ropinirole.
ZiprasidoneZiprasidone may increase the sedative activities of Ropinirole.
ZiprasidoneThe metabolism of Ziprasidone can be decreased when combined with Ropinirole.
ZolazepamZolazepam may increase the sedative activities of Ropinirole.
ZolmitriptanThe metabolism of Zolmitriptan can be decreased when combined with Ropinirole.
ZolpidemZolpidem may increase the sedative activities of Ropinirole.
ZolpidemThe metabolism of Zolpidem can be decreased when combined with Ropinirole.
ZonisamideZonisamide may increase the sedative activities of Ropinirole.
ZopicloneZopiclone may increase the sedative activities of Ropinirole.
ZotepineZotepine may increase the sedative activities of Ropinirole.
ZuclopenthixolZuclopenthixol may increase the sedative activities of Ropinirole.
ZuclopenthixolThe metabolism of Zuclopenthixol can be decreased when combined with Ropinirole.
Food InteractionsNot Available

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
agonist
General Function:
G-protein coupled amine receptor activity
Specific Function:
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
Gene Name:
DRD3
Uniprot ID:
P35462
Molecular Weight:
44224.335 Da
References
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
  3. Lam YW: Clinical pharmacology of dopamine agonists. Pharmacotherapy. 2000 Jan;20(1 Pt 2):17S-25S. [PubMed:10641988 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
agonist
General Function:
Potassium channel regulator activity
Specific Function:
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
Gene Name:
DRD2
Uniprot ID:
P14416
Molecular Weight:
50618.91 Da
References
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. de Mey C, Enterling D, Meineke I, Yeulet S: Interactions between domperidone and ropinirole, a novel dopamine D2-receptor agonist. Br J Clin Pharmacol. 1991 Oct;32(4):483-8. [PubMed:1683559 ]
  3. Iida M, Miyazaki I, Tanaka K, Kabuto H, Iwata-Ichikawa E, Ogawa N: Dopamine D2 receptor-mediated antioxidant and neuroprotective effects of ropinirole, a dopamine agonist. Brain Res. 1999 Aug 14;838(1-2):51-9. [PubMed:10446316 ]
  4. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
  5. Lam YW: Clinical pharmacology of dopamine agonists. Pharmacotherapy. 2000 Jan;20(1 Pt 2):17S-25S. [PubMed:10641988 ]
  6. Matsukawa N, Maki M, Yasuhara T, Hara K, Yu G, Xu L, Kim KM, Morgan JC, Sethi KD, Borlongan CV: Overexpression of D2/D3 receptors increases efficacy of ropinirole in chronically 6-OHDA-lesioned Parkinsonian rats. Brain Res. 2007 Jul 30;1160:113-23. Epub 2007 May 26. [PubMed:17573046 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Sh3 domain binding
Specific Function:
Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
Gene Name:
DRD4
Uniprot ID:
P21917
Molecular Weight:
48359.86 Da
References
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Serotonin receptor activity
Specific Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G pro...
Gene Name:
HTR1A
Uniprot ID:
P08908
Molecular Weight:
46106.335 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Serotonin receptor activity
Specific Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate c...
Gene Name:
HTR1D
Uniprot ID:
P28221
Molecular Weight:
41906.38 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Serotonin receptor activity
Specific Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins ...
Gene Name:
HTR2B
Uniprot ID:
P41595
Molecular Weight:
54297.41 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
G-protein coupled amine receptor activity
Specific Function:
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Gene Name:
DRD1
Uniprot ID:
P21728
Molecular Weight:
49292.765 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
G-protein coupled amine receptor activity
Specific Function:
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Gene Name:
DRD5
Uniprot ID:
P21918
Molecular Weight:
52950.5 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Serotonin receptor activity
Specific Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of ...
Gene Name:
HTR1B
Uniprot ID:
P28222
Molecular Weight:
43567.535 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Virus receptor activity
Specific Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates...
Gene Name:
HTR2A
Uniprot ID:
P28223
Molecular Weight:
52602.58 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Serotonin receptor activity
Specific Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modul...
Gene Name:
HTR2C
Uniprot ID:
P28335
Molecular Weight:
51820.705 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Thioesterase binding
Specific Function:
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianser...
Gene Name:
ADRA2A
Uniprot ID:
P08913
Molecular Weight:
48956.275 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Epinephrine binding
Specific Function:
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phent...
Gene Name:
ADRA2B
Uniprot ID:
P18089
Molecular Weight:
49565.8 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Protein homodimerization activity
Specific Function:
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Gene Name:
ADRA2C
Uniprot ID:
P18825
Molecular Weight:
49521.585 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrateinhibitor
General Function:
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N...
Gene Name:
CYP1A2
Uniprot ID:
P05177
Molecular Weight:
58293.76 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
  2. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Vitamin d3 25-hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiot...
Gene Name:
CYP3A4
Uniprot ID:
P08684
Molecular Weight:
57342.67 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
  2. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
Gene Name:
CYP2D6
Uniprot ID:
P10635
Molecular Weight:
55768.94 Da
References
  1. Kvernmo T, Houben J, Sylte I: Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Curr Top Med Chem. 2008;8(12):1049-67. [PubMed:18691132 ]
  2. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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Drug created on June 13, 2005 07:24 / Updated on September 29, 2016 02:25