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Identification
Name 19-norandrostenedione
Accession Number DB01434
Type small molecule
Groups experimental, nutraceutical
Description

19-Norandrostenedione refers to two steroid isomers that are marketed as dietary supplements and mainly used by body builders.
Structure Thumb
Download: MOL | SDF | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms
delta4-Estrene-3,17-dione
Salts Not Available
Brand names
Name Company
19-N-Andro
Bolandione
Proven Pure 19-Norandrostenedione
Brand mixtures Not Available
Categories Not Available
CAS number 734-32-7
Weight Average: 272.382
Monoisotopic: 272.177630012
Chemical Formula C18H24O2
InChI Key InChIKey=JRIZOGLBRPZBLQ-QXUSFIETSA-N
InChI
InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-16H,2-9H2,1H3/t13-,14+,15+,16-,18-/m0/s1
Plain Text
IUPAC Name
(1S,2R,10R,11S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione
SMILES
[H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]
Plain Text
Mass Spec Not Available
Taxonomy
Kingdom Organic
Classes
  • Steroids and Steroid Derivatives
Substructures
  • Steroids and Steroid Derivatives
  • Carbonyl Compounds
  • Alkanes and Alkenes
  • Cyclohexenes and Derivatives
  • Ketones
Pharmacology
Indication The claim that supplemental 19-norandrostenedione has anabolic effects is unsubstantiated.
Pharmacodynamics Not Available
Mechanism of action 19-Norandrostenedione may be metabolized to 19-nortestosterone in both men and women. 19-Norandrostenedione, also known as nandrolone, is the basic substance of some very popular injectable anabolic steroids. 19-Norandrostenedione is not metabolized to testosterone. Whether increases in 19-nortestosterone levels that may be produced by taking oral 19-norandrostenedione would be sustained long enough to show increase in nitrogen retention and muscle strength and mass is unknown.
Absorption Absorption appears variable, but some absorption does occur
Volume of distribution Not Available
Protein binding Not Available
Metabolism Specific metabolites of 19-nor-5-androstene-3, 17-dione are 19-nordehydroandrosterone and 19-nordehydroepiandrosterone.
Route of elimination Not Available
Half life Not Available
Clearance Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Pathways Not Available
Pharmacoeconomics
Manufacturers Not Available
Packagers Not Available
Dosage forms
Form Route Strength
Powder Oral
Tablet Oral
Prices Not Available
Patents Not Available
Properties
State solid
Experimental Properties Not Available
Predicted Properties
Property Value Source
water solubility 4.54e-02 g/l ALOGPS
logP 2.53 ALOGPS
logP 3.63 ChemAxon
logS -3.8 ALOGPS
pKa (strongest acidic) 19.19 ChemAxon
pKa (strongest basic) -4.7 ChemAxon
physiological charge 0 ChemAxon
hydrogen acceptor count 2 ChemAxon
hydrogen donor count 0 ChemAxon
polar surface area 34.14 ChemAxon
rotatable bond count 0 ChemAxon
refractivity 79.13 ChemAxon
polarizability 31.54 ChemAxon
References
Synthesis Reference Not Available
General Reference Not Available
External Links
Resource Link
KEGG Compound C14500 Link_out
PubChem Compound 92834 Link_out
PubChem Substance 46505377 Link_out
ChemSpider 83803 Link_out
PDRhealth http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/19n_0010.shtml Link_out
ATC Codes Not Available
AHFS Codes Not Available
PDB Entries Not Available
FDA label Not Available
MSDS Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available
Comments
Drug created on July 24, 2007 14:36 / Updated on February 08, 2013 16:20