Banner
targets (1)
for drugs
Identification
Name Camphor
Accession Number DB01744 (EXPT00827)
Type small molecule
Groups experimental
Description

A bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. [PubChem]
Structure Thumb
Download: MOL | SDF | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms Not Available
Salts Not Available
Brand names Not Available
Brand mixtures Not Available
Categories
  • Anti-Infective Agents, Local
CAS number 76-22-2
Weight Average: 152.2334
Monoisotopic: 152.120115134
Chemical Formula C10H16O
InChI Key InChIKey=DSSYKIVIOFKYAU-OIBJUYFYSA-N
InChI
InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m0/s1
Plain Text
IUPAC Name
(1S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
SMILES
CC1(C)[C@H]2CC[C@]1(C)C(=O)C2
Plain Text
Mass Spec Not Available
Taxonomy
Kingdom Not Available
Classes Not Available
Substructures Not Available
Pharmacology
Indication Not Available
Pharmacodynamics Not Available
Mechanism of action Not Available
Absorption Not Available
Volume of distribution Not Available
Protein binding Not Available
Metabolism
Not Available
Route of elimination Not Available
Half life Not Available
Clearance Not Available
Toxicity Not Available
Affected organisms Not Available
Pathways Not Available
Pharmacoeconomics
Manufacturers Not Available
Packagers
Dosage forms Not Available
Prices Not Available
Patents Not Available
Properties
State solid
Experimental Properties
Property Value Source
melting point 180 °C PhysProp
boiling point 204 °C PhysProp
water solubility 1600 mg/L (at 25 °C) YALKOWSKY,SH & HE,Y (2003)
logP 2.38 DAYLIGHT (1999)
Predicted Properties
Property Value Source
water solubility 8.80e-01 g/l ALOGPS
logP 2.85 ALOGPS
logP 2.55 ChemAxon
logS -2.2 ALOGPS
pKa (strongest basic) -7.5 ChemAxon
physiological charge 0 ChemAxon
hydrogen acceptor count 1 ChemAxon
hydrogen donor count 0 ChemAxon
polar surface area 17.07 ChemAxon
rotatable bond count 0 ChemAxon
refractivity 44.49 ChemAxon
polarizability 17.73 ChemAxon
References
Synthesis Reference Not Available
General Reference Not Available
External Links
Resource Link
KEGG Drug D00098 Link_out
KEGG Compound C00808 Link_out
PubChem Compound 444294 Link_out
PubChem Substance 46508429 Link_out
ChemSpider 2441 Link_out
ChEBI 36773 Link_out
ChEMBL 36773 Link_out
PharmGKB PA448759 Link_out
HET CAM Link_out
Drug Product Database 50040 Link_out
Drugs.com http://www.drugs.com/cdi/camphor-liquid.html Link_out
Wikipedia http://en.wikipedia.org/wiki/Camphor Link_out
ATC Codes Not Available
AHFS Codes Not Available
PDB Entries
FDA label Not Available
MSDS Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available
Targets

1. Cytochrome P450-cam

Pharmacological action: unknown

Involved in a camphor oxidation system

Organism class: bacterial
UniProt ID: P00183 Link_out
Gene: camC
Protein Sequence: FASTA
Gene Sequence: FASTA
SNPs: SNPJam Report Link_out

References:
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
Comments
Drug created on June 13, 2005 07:24 / Updated on February 08, 2013 16:20