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Identification
NameSalicylic acid
Accession NumberDB00936  (APRD01605, DB01398)
TypeSmall Molecule
GroupsApproved, Vet Approved
Description

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.

Structure
Thumb
Synonyms
2-Carboxyphenol
2-Hydroxybenzoic acid
O-carboxyphenol
O-hydroxybenzoic acid
Salicylic acid
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Aliclenshampoo60 mg/mLtopicalPrasco Laboratories2011-02-022016-04-05Us
Bensal Hpointment30 mg/gtopicalSmg Pharmaceuticals, Llc1998-10-012016-04-05Us
Bioelements Active Astringentliquid.5 mL/100mLtopicalBioelements2009-01-012016-04-05Us
Clearasil Completelotion2 %topicalProcter & Gamble IncNot applicableNot applicableCanada
Clearasil Stayclear Acne Defense Cleanserlotion2 %topicalProcter & Gamble IncNot applicableNot applicableCanada
Clearasil Stayclear Zone Control Clearstickliquid2 %topicalProcter & Gamble IncNot applicableNot applicableCanada
Dhs Salshampoo3.0 %topicalSeaford Pharmaceuticals IncNot applicableNot applicableCanada
Dodds Extra Strength Tab 500mgtablet500 mgG.T. Fulford Pharmaceuticals1988-12-311998-06-25Canada
Dodds Pillstablet325 mgG.T. Fulford Pharmaceuticals1985-12-311998-06-25Canada
Dodds Pillstablet325 mgG.T. Fulford Pharmaceuticals1985-12-311998-06-25Canada
Exorex Acne Formulalotion0.5 %topicalMeyer Zall Laboratories Pty Ltd.Not applicableNot applicableCanada
Imba - Crm 3%cream3 %The Emu Man Company L.C.1996-12-311999-07-08Canada
Keralytgel6 g/100gtopicalSummers Laboratories Inc2009-11-012016-04-05Us
KeralytkitSummers Laboratories Inc2009-11-012016-04-05Us
Keralytshampoo6 g/92.6mLtopicalSummers Laboratories Inc2009-11-012016-04-05Us
Salacyncream24 g/400gtopicalStratus Pharamceuticals, Inc2009-03-232016-04-05Us
Salacynlotion24.84 mg/414mLtopicalStratus Pharamceuticals, Inc2009-03-232016-04-05Us
Salexshampoo60 mg/mLtopicalCoria Laboratories2004-10-012016-04-05Us
Salexlotion60 mg/mLtopicalCoria Laboratories2004-10-012016-04-05Us
Salexcream60 mg/gtopicalCoria Laboratories2004-06-012016-04-05Us
Salicylic Acidliquid260 mg/mLtopicalRochester Pharmaceuticals2011-03-302016-04-05Us
Salicylic Acidgel60 mg/gtopicalExact Rx, Inc.2011-08-012016-04-05Us
Salicylic AcidkitSeton Pharmaceuticals2008-11-012016-04-05Us
Salicylic AcidkitSeton Pharmaceuticals2008-11-012016-04-05Us
Salicylic Acidlotion6 mL/100mLtopicalPerrigo New York Inc2007-09-272016-04-05Us
Salicylic Acidcream27.24 g/gtopicalPru Gen, Inc.2011-05-012016-04-05Us
Salicylic Acidsolution275 mg/mLtopicalTrinity Pharmaceuticals, LLC2013-11-162016-04-05Us
Salicylic Acidcream6 g/100gtopicalPerrigo New York Inc2007-09-072016-04-05Us
Salicylic Acidliquid275 mg/mLtopicalAcella Pharmaceuticals, LLC2011-09-212016-04-05Us
Salicylic Acidlotion60 mg/gtopicalTrinity Pharmaceuticals, LLC2012-12-102016-04-05Us
Salicylic Acidshampoo6 mL/100mLtopicalPerrigo New York Inc2008-08-252016-04-05Us
Salicylic Acidgel60 mg/gtopicalAcella Pharmaceuticals, LLC2011-05-192016-04-05Us
Salicylic Acidcream60 mg/gtopicalTrinity Pharmaceuticals, LLC2012-12-102016-04-05Us
Salicylic AcidkitExact Rx, Inc.2011-08-012016-04-05Us
Salicylic Acidaerosol, foam6 g/100gtopicalAcella Pharmaceuticals, LLC2011-04-272016-04-05Us
Salicylic Acidsolution285 mg/mLtopicalKmm Pharmaceuticals, Llc2011-06-012016-04-05Us
Salicylic Acidcream60 mg/gtopicalExact Rx, Inc.2011-08-012016-04-05Us
Salicylic Acidaerosol, foam6 g/100gtopicalAcella Pharmaceuticals, LLC2010-07-162016-04-05Us
Salicylic Acidliquid275 mg/mLtopicalRochester Pharmaceuticals2011-11-072016-04-05Us
Salicylic Acidlotion60 mg/gtopicalExact Rx, Inc.2011-08-012016-04-05Us
Salicylic Acid 6 Percentshampoo6 mg/100mLtopicalPru Gen, Inc.2009-01-012016-04-05Us
Saliject 570mg/mlliquid570 mgintravenousOmega Laboratories Ltd1985-12-31Not applicableCanada
Salvaxaerosol, foam3.88 g/70gtopicalQuinnova Pharmaceuticals, Inc.2009-01-012016-04-05Us
Sensitive Skin Facial Astringentliquid0.5 %Scott Chemical Canada2000-03-012009-08-26Canada
Trans-plantar 20mm Pls 15%plaster15 %Bradley Pharmaceuticals Inc1990-12-312009-06-29Canada
Trans-ver-sal 6mm Pls 15%plaster15 %Bradley Pharmaceuticals Inc1989-12-312009-06-29Canada
Ultrasal-ERsolution285 mg/mLtopicalElorac, Inc.2014-01-302016-04-05Us
Virasalsolution275 mg/mLtopicalElorac, Inc.2011-04-012016-04-05Us
Generic Prescription ProductsNot Available
Over the Counter Products
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24 Hour Pimple PunisherkitKATE SOMERVILLE SKINCARE, LLC2014-06-222016-04-05Us
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28 Remedy Balancing Toner 10mlcream.001 mg/10mLtopicalNo Ts Co Ltd2015-09-012016-04-05Us
Ac Out Spot Stop Serumliquid.1 mg/100mLtopicalThe Doctors Cosmetics Co., Ltd2012-09-272016-04-05Us
Acence Tea Tree Tock Blemish Spotsolution22.5 mg/15mLtopicalMizon Co., Ltd.2015-12-012016-04-05Us
Acnecream14 g/100gtopicalGREENBRIER INTERNATIONAL INC2013-01-012016-04-05Us
Acne and Blemish Targetgel2 g/100gtopicalBiocosmetics Research Labs2003-02-132016-04-05Us
Acne and Oil Controlgel2 g/100mLtopicalSkin Authority Llc2012-04-192016-04-05Us
Acne Beauty Benefit Lightcream.5 g/100gtopicalGreenbrier International, Inc.2015-05-052016-04-05Us
Acne Beauty Benefit Mediumcream.5 g/100gtopicalGreenbrier International, Inc.2015-05-052016-04-05Us
Acne Body Washgel7 mg/354mgtopicalChina Ningbo Shangge Cosmetic Technology Corp.2013-11-182016-04-05Us
Acne Body Washgel7 mg/354mgtopicalRejoice International2013-11-182016-04-05Us
Acne Cleansinggel.02158 g/100mLtopicalCLINIQUE LABORATORIES INC.2014-10-012016-04-05Us
Acne Cleansing Padsliquid.02 g/1topicalDR LIN SKINCARE2013-06-132016-04-05Us
Acne Cleansing Wipesliquid.02 g/1topicalDR LIN SKINCARE2013-06-132016-04-05Us
Acne Control Oil-free Cleansingliquid29.2 mg/1topicalPersonal Care Products, LLC2015-10-012016-04-05Us
Acne Correcting Cleansergel2 g/100mLtopicalCEN BEAUTY LLC2013-02-212016-04-05Us
Acne Fightinggel1 g/100mLtopicalJ. A. Cosmetics U.S. INC2015-01-272016-04-05Us
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Acne Lab Foam Cleanserliquid.75 mg/150mLtopicalAMAROS CO., LTD.2013-09-012016-04-05Us
Acne Medicated Gelgel0.5 %topicalTp Health Ltd.1998-11-122010-03-01Canada
Acne Padspad2 %topicalFlageoli Limited2002-07-012008-08-26Canada
Acne Pronegel2 g/100mLtopicalBiological Health Group Corporation2015-06-182016-04-05Us
Acne Pronegel1.5 g/100mLtopicalBiological Health Group Corporation2015-06-182016-04-05Us
Acne Scrubgel21 mg/mLtopicalWal Mart Stores, Inc2015-01-152016-04-05Us
Acne Serumgel.01 g/gtopicalUniversal Packaging Systems, Inc. Dba: Paklab2015-10-262016-04-05Us
Acne Solutionsolution.2 g/40gtopicalBiometics Co.,Ltd.2014-05-012016-04-05Us
Acne Solutions Clarifyingliquid1.5 mL/100mLtopicalCLINIQUE LABORATORIES INC2006-09-012016-04-05Us
Acne Solutions Cleansing Bar for Face and Bodysoap2 g/100gtopicalCLINIQUE LABORATORIES INC2006-04-012016-04-05Us
Acne Solutions Cleansing Foamliquid2 mL/100mLtopicalCLINIQUE LABORATORIES INC2006-12-122016-04-05Us
Acne Solutions Clearing Concealer Acne Medication All Skin Typeslotion1 mL/100mLtopicalCLINIQUE LABORATORIES INC2008-04-022016-04-05Us
Acne Solutions Liquid Makeup Salicylic Acid Acne Treatmentliquid.5 mL/100mLtopicalCLINIQUE LABORATORIES INC2009-04-092016-04-05Us
Acne Solutions Oil Control Cleansing Mask Acne Medication All Skin Typescream1 mL/100mLtopicalCLINIQUE LABORATORIES INC2007-09-012016-04-05Us
Acne Solutions Spot Healing Acne Medicationgel.5 mL/100mLtopicalCLINIQUE LABORATORIES INC2008-12-012016-04-05Us
Acne Spot Treatmentliquid.02 mg/mLtopicalCos Medical Technologies2015-11-042016-04-05Us
Acne Stick Gelgel0.5 %topicalTp Health Ltd.Not applicableNot applicableCanada
Acne Toner Acne Clearing Systemliquid.5 g/.5mLtopicalBioelements2015-04-102016-04-05Us
Acne Toner Biolementscream.5 g/100mLtopicalBioelements, Inc.2013-06-172016-04-05Us
Acne Treatmentgel.005 mg/gtopicalNatureplex LLC2007-01-022016-04-05Us
Acne Treatment Clear Gel - Maximum Strengthgel5 mg/gtopicalMc Cure Health Solutions Inc.2015-03-272016-04-05Us
Acne Washlotion20.6 mg/mLtopicalDolgencorp, LLC2008-06-082016-04-05Us
Acne Washliquid1 %topicalFlageoli Limited2000-05-062007-08-30Canada
Acne Wash Oil-freeliquid2 g/100mLtopicalAmerican Sales Company2013-11-152016-04-05Us
Acne Wipesswab5 mg/mLtopicalGreenbrier International, Inc.2012-12-112016-04-05Us
Acne Wipesswab5 mg/1000mgtopicalJiangsu Terra Medical Technology Co Ltd2015-09-302016-04-05Us
Acne Wipesswab.5 g/100gtopicalZhejiang Greenface Housewares Co., Ltd.2015-05-062016-04-05Us
Acneclirlotion.02 mL/mLtopicalPhillips Company2010-12-302016-04-05Us
Acneenlotion.02 mL/mLtopicalPhillips Company2010-12-302016-04-05Us
Acnefree 2-IN-1 Acne Wipescloth5 mg/1topicalValeant Pharmaceuticals North America LLC2014-11-012016-04-23Us
Acnefree Body Clearingspray2.84 g/142gtopicalValeant Pharmaceuticals North America LLC2014-01-142016-04-23Us
Acnefree Daily Skin Therapy Acne Padssolution20 mg/1topicalValeant Pharmaceuticals North America LLC2016-01-292016-04-23Us
Acnefree Daily Skin Therapy Acne Washliquid2 g/100mLtopicalValeant Pharmaceuticals North America LLC2016-02-042016-04-23Us
Acnefree Dryinglotion10 mg/mLtopicalValeant Pharmaceuticals North America LLC2014-10-152016-04-23Us
Acnefree Energizing 3-IN-1 Acne Wipescloth5 mg/1topicalValeant Pharmaceuticals North America LLC2014-01-142016-06-16Us
Acnevir Facial Washsoap2 g/100gtopicalAlva Amco Pharmacal Companies, Inc.2009-12-012016-04-05Us
Acneworxgel.6 g/30mLtopicalDerm Worx Incorporated2008-01-142016-04-05Us
Acnex Liq 2%liquid2 %topicalDermtek Pharma Inc1987-12-312003-12-15Canada
Acnezzol Baselotion1 mg/mLtopicalSOLUTION INTERNATIONAL INC2013-01-102016-04-05Us
Acnomel Acnee Maskcream1.5 %topicalChattem Canada1995-12-311999-07-25Canada
Acnopur Lotion Exfoliante Clarifiantelotion0.5 %topicalBiotherm Canada2002-03-012009-11-03Canada
Acnopur Soin Hydratant Regulateurcream2 %topicalBiotherm Canada2002-03-012009-11-03Canada
Acnopur Traitement Urgence Acnecream2 %topicalBiotherm Canada2002-03-012009-11-03Canada
Acpuris Intensive Spot Treatmentcream.3 mL/15mLcutaneousMEDIWAY KOREA CO., LTD.2010-09-012016-04-05Us
Actiogen Acne Dots Treatmentpatch2 mg/100mgtopicalActiogen Corp2014-08-012016-04-05Us
Active Clear Facial Washliquid20 mg/mLtopicalSeacret Spa Llc2015-06-122016-04-05Us
Advanced Acne Spot Treatmentgel2 g/100gtopicalShanghai Weierya Daily Chemicals Factory2016-01-112016-04-05Us
Advanced Acne Spot Treatment Cvslotion2 g/100mLtopicalCVS2014-12-222016-04-05Us
Aetna Callus Removerplaster.4 1/1001topicalAetna Felt Corp1995-10-312016-04-05Us
Aetna Callus Removerplaster40 1/1topicalAetna Felt Corp1995-10-312016-04-05Us
AF Foam Sensitive Acne Pore Cleanseraerosol, foam1.5 g/100gtopicalUniversity Medical Pharmaceuticals Corp2011-11-152016-04-05Us
Age Defying Blemish Treatmentcream2 g/100mLtopicalWasatch Product Development, LLC2013-10-242016-04-05Us
Ala-septiccream2 g/100gtopicalAla Septic Pharmaceutical Research Llc2013-10-012016-04-05Us
Alba Acnedote Clean Treat Cleansing Towelettecloth2 g/101topicalThe Hain Celestial Group, Inc.2013-11-262016-04-05Us
Alba Acnedote Clean Treat Towelettecloth2 g/301topicalThe Hain Celestial Group, Inc.2013-11-262016-04-05Us
Alba Acnedote Invisible Treatmentlotion2 g/100gtopicalThe Hain Celestial Group, Inc.2013-10-012016-04-05Us
Alba Good and Clean Gentle Acne Washlotion1 g/100gtopicalThe Hain Celestial Group, Inc.2013-03-072016-04-05Us
Alba Natural Acnedotelotion2 g/100gtopicalThe Hain Celestial Group, Inc.2010-02-182016-04-05Us
Alba Natural Acnedote Astringentlotion2 mL/100mLtopicalThe Hain Celestial Group, Inc.2010-01-212016-04-05Us
Alba Natural Acnedote Face Body Scrubcream2 g/100gtopicalThe Hain Celestial Group, Inc.2010-01-212016-04-05Us
Alba Natural Acnedote Washlotion2 mL/100mLtopicalThe Hain Celestial Group, Inc.2010-01-212016-04-05Us
Almay (hypo-allergen.)oil Stop.anti-acne Gelgel.5 %topicalAlmay Toronto Inc.1993-12-311996-09-09Canada
Almay Clear Complexion Blemish Clearing Compactcream1.0 %topicalRevlon Canada Inc2004-02-112007-07-24Canada
Almay Clear Complexion Pressed Powderpowder0.6 %topicalRevlon Canada Inc2004-02-112009-07-13Canada
Almay Stay Clean Medicated Pore Stripsstrip1.4 %topicalAlmay Toronto Inc.1998-11-302001-07-26Canada
Almay(hypo-allergenic)clean-out Cleans.padsliquid; pad.5 %topicalAlmay Toronto Inc.1993-12-311996-09-09Canada
Almay(hypo-allergenic)extra Clear Skin Astr.liquid.5 %topicalAlmay Toronto Inc.1993-12-311996-09-09Canada
Alsora Psoriasislotion250 g/5gtopicalIsdin Corp2015-08-172016-04-05Us
Alsora Psoriasisshampoo200 g/6gtopicalIsdin Corp2015-08-172016-04-05Us
Alsora Psoriasis Creamcream50 g/gtopicalIsdin Corp2015-08-172016-04-05Us
Always Pure Spot for Nightcream.08 g/20mLtopicalDms International Co., Ltd.2016-02-012016-04-05Us
Ambi Even and Clear Exfoliating Washcream5 mg/gtopicalValeant Pharmaceuticals North America LLC2014-07-152016-04-23Us
Ambi Even and Clear Exfoliating Washcream5 mg/gtopicalValeant Pharmaceuticals North America LLC2014-11-102016-04-23Us
Ambi Even and Clear Foaming Cleanserliquid5 mg/mLtopicalValeant Pharmaceuticals North America LLC2014-06-152016-04-23Us
Anti Acne Calming Correctorgel15 uL/mLtopicalH2 O Plus2010-03-012016-04-05Us
Anti Acne Clarifying Face Washgel15 uL/mLtopicalH2 O Plus2009-04-012016-04-05Us
Anti Acne Control Formula - Lot Top 1%lotion1 %topicalClinique Laboratories Dist1996-09-042001-09-24Canada
Anti Acne Exfoliating Cleansing Padsswab10 uL/mLtopicalH2 O Plus2008-09-012016-04-05Us
Anti Acne Spot Treatment 1%jelly1 %topicalClinique Laboratories Dist1994-12-312001-07-30Canada
Anti Dandruffrinse2 g/397gtopicalThe Hain Celestial Group, Inc.2014-01-172016-04-05Us
Anti Dandruffshampoo2 g/414gtopicalThe Hain Celestial Group, Inc.2014-01-292016-04-05Us
Anti-acnelotion2 g/100gtopicalBiocosmetics Research Labs2008-01-232016-04-05Us
Anti-blemishdisc20 mg/1topicalKamins Dermatologics Inc.2010-08-092016-04-05Us
Anti-blemish Cleansercream14 g/100gtopicalBicooya Cosmetics Limited2014-12-162016-04-05Us
Anti-blemish Concealerstick2 g/100gtopicalHatchbeauty Products Llc2015-06-182016-04-05Us
Anti-blemish Foundation Primer Acne Treatment Gel Merle Normangel2 g/100gtopicalMerle Norman Cosmetics, Inc2014-06-302016-04-05Us
Anti-blemish Matte Primerlotion1 mg/100mLtopicalJouer Cosmetics Llc2014-01-012016-04-05Us
Anti-clog Concentrate Bioelements, Inc.cream5 mL/100mLtopicalBioelements2010-09-092016-04-05Us
Anti-dandruffshampoo20 mg/mLtopicalMineral Fusion Natural Brands2013-08-012016-04-05Us
Antiac Acne Clearingspray5 mg/mLtopicalSalcura Ltd2013-07-132016-04-05Us
Aroma A1 Skinlotion.75 mg/150mLtopicalGOWOONSESANG COSMETICS CO., LTD.2012-10-012016-04-05Us
Artistry Essentials Anti-blemish Acne Treatmentlotion1.1 mL/100mLtopicalAccess Business Group2011-07-272016-04-05Us
Asd 3-IN-1gel2 g/100gtopicalAlmen Cosmetic Group AB2015-01-232016-04-05Us
Asd 3-IN-1gel2 g/100gtopicalSwemedeq AB2015-01-232016-04-05Us
Asepxia Acne Medication Wipescloth20 mg/mLtopicalGenomma Labs2015-07-012016-04-05Us
Asepxia Facial Cleansingcloth.5 g/100gtopicalFischer Pharmaceuticals Ltd.2011-01-302016-04-05Us
Assured Acne Creamcream.5 mL/100mLtopicalHangzhou Mino Daily Chemicals Co.Ltd.2010-06-012016-04-05Us
Atopalm Acne Controllinglotion2 mL/100mLtopicalNeo Pharm Co., Ltd.2011-11-042016-04-05Us
Aveeno Acne Treatment Barsoap bar0.50 %topicalJohnson & Johnson Inc2000-05-012002-08-02Canada
Aveeno Active Naturalssoap.5 g/100gtopicalBradford Soap Works, Inc.2007-02-202016-04-05Us
Aveeno Active Naturals Clear Complexion Daily Cleansing Padscloth6 mg/1topicalJohnson & Johnson Consumer Inc.2016-03-012016-04-01Us
Aveeno Active Naturals Clear Complexion Daily Moisturizerlotion5 mg/mLtopicalJohnson & Johnson Consumer Inc.2004-01-012016-04-05Us
Aveeno Cleansing Bar for Acne-prone Skin .5%soap bar.5 %topicalS.C. Johnson And Son Ltd1960-12-311996-09-13Canada
Aveeno Cleansing Bar-for Acne-prone Skinsoap bar.5 %topicalS.C. Johnson And Son Ltd1960-12-312000-07-07Canada
Aveeno Clear Complexion Cleansercream20 mg/gtopicalJohnson & Johnson Consumer Products Company, Division of Johnson & Johnson Consumer Companies, Inc.2013-06-202016-04-05Us
Aveeno Clear Complexion Cleansing Barsoap5 mg/gtopicalJohnson & Johnson Consumer Inc.2013-06-122016-06-01Us
Aveeno Clear Complexion Daily Cleansingcloth5 mg/1topicalJohnson & Johnson Consumer Inc.2013-05-192017-12-01Us
Aveeno Clear Complexion Foaming Cleanserliquid5 mg/mLtopicalJohnson & Johnson Consumer Products Company, Division of Johnson & Johnson Consumer Companies, Inc.2011-08-232016-04-05Us
Aveeno Favorites From Clear ComplexionkitJohnson & Johnson Consumer Inc.2015-12-022016-04-05Us
Avon Anew Perfecting Lotion for Problem Skinlotion0.5 %topicalAvon Canada Ulc1997-03-132004-07-29Canada
Avon Clear Finish Great Complexion Concealercream2.0 %topicalAvon Canada Ulc2001-11-222005-07-29Canada
Avon Clear Finish Great Complexion Foundationlotion2.0 %topicalAvon Canada Ulc2001-09-252006-04-27Canada
Avon Clear Finish Oil-free Foundationlotion0.7 %topicalAvon Canada Ulc1999-07-232003-04-15Canada
Avon Clearskin 2 Medicated Gel Washgel2 %topicalAvon Canada Ulc1997-03-131999-08-12Canada
Avon Clearskin 2 Triple Action Astringent Cleansing Lotionlotion2 %topicalAvon Canada Ulc1997-02-201999-08-12Canada
Avon Clearskin Acne Defense Stickstick2 %topicalAvon Canada Ulc1999-07-232004-07-29Canada
Avon Clearskin Astringent Cleansing Lotion Extra Strengthliquid2 %topicalAvon Canada Ulc1999-02-112004-07-29Canada
Avon Clearskin Invisible Blemish Correctorlotion1.5 %topicalAvon Canada Ulc2003-10-302009-08-24Canada
Avon Clearskin Overnight Acne Treatmentgel0.5 %topicalAvon Canada Ulc1999-02-112001-11-05Canada
Avon Clearskin Overnight Blemish Treatmentliquid1.5 %topicalAvon Canada Ulc2001-11-052007-07-26Canada
Avon Clearskin Purifying Astringentliquid2 %topicalAvon Canada Ulc2003-07-012005-07-29Canada
Avon Clearskin Purifying Gel Cleansergel2 %topicalAvon Canada Ulc2003-07-012009-08-24Canada
Avon Clearskin Targeted Blemish Removerlotion2 %topicalAvon Canada Ulc2001-09-252008-07-10Canada
Awaken By Quality Choice Ultra Clean Daily Face Washcream2 g/100gtopicalChain Drug Marketing Association2014-09-012016-04-05Us
Awaken Oil-free Daily Face Washcream2 g/100mLtopicalChain Drug Marketing Association2014-09-012016-04-05Us
Band-aid Brand Medicated Corn Removerpad40 %topicalJohnson & Johnson Inc2000-03-312003-08-25Canada
Bareminerals Blemish Remedy Acne Treatment Gelee Cleanseremulsion10 mg/gtopicalBare Escentuals Beauty, Inc.2016-01-302016-04-05Us
Benefit Boo Boo Zap Medicated Acne Treatmentgel5 mg/mLtopicalBenefit Cosmetics, LLC2011-12-292016-04-05Us
Benzacgel2 g/100mLtopicalGalderma Laboratories, L.P.2014-12-012016-04-23Us
Benzacsolution.5 g/100mLtopicalGalderma Laboratories, L.P.2014-12-012016-04-23Us
Benzacsolution.5 g/100mLtopicalGalderma Laboratories, L.P.2014-12-012016-04-23Us
Benzacsolution.5 g/100mLtopicalGalderma Laboratories, L.P.2014-12-012016-04-23Us
Benzac - Complete Acne Solution RegimenkitGalderma Laboratories, L.P.2014-12-012016-04-23Us
Best Choice Oil-free Acne Wash Foaming Scrublotion20 mg/mLtopicalValu Merchandisers Company2012-12-152016-04-05Us
Beta Complex Acne Treatmentlotion1 %topicalBrandselite International Corporation, Erno Lazlo Division1995-12-312000-01-31Canada
Better Braids Medicatedshampoo.24 mg/355mLtopicalKeystone Laboratories1993-08-012016-04-05Us
Bioarpilointment2.8 g/140gtopicalBIOARPIL USA, INC.2012-07-012016-04-05Us
Biocure Gel Exfoliant Antipelliculairegel1.8 %topicalYves Rocher Inc.2000-08-152004-08-06Canada
Biocure: Shampooing Antipelliculairegel1.8 %topicalYves Rocher Inc.2000-01-012005-08-15Canada
Bioelements Amino Maskcream2 mL/100mLtopicalBioelements2009-01-012016-04-05Us
Bioelements Spotless Cleansergel2 mL/100mLtopicalBioelements Inc.2010-05-052016-04-05Us
Bioré Blemish Fighting Cleanserlotion0.5 %topicalJergens Canada Inc.2000-07-012005-08-05Canada
Biore Blemish Fighting Ice Cleanserliquid4.3 g/200mLtopicalKao Brands Company2011-12-282016-04-05Us
Biore Blemish Treating Astringentliquid4.56 g/236mLtopicalKao Brands Company2011-11-092016-04-05Us
Biore Blemish Undercover Agentcream2 %topicalJergens Canada Inc.2001-06-182005-08-05Canada
Biore Pore Unclogging Scrubliquid2.8 g/141gtopicalKao Brands Company2011-12-282016-04-05Us
Biore Warming Anti-blackhead Cleanserliquid2.54 g/127gtopicalKao Brands Company2011-12-282016-04-05Us
Blackhead Cleaning Scrubcream2 g/100gtopicalShanghai Weierya Daily Chemicals Factory2016-01-112016-04-05Us
Blackhead Clearing Scrublotion2 g/100gtopicalKmart Corporation2010-01-152016-04-05Us
Blackhead Clearing Scrubgel19.4 mg/gtopicalH E B2009-06-232016-04-05Us
Blackhead Clearing Scrubgel19.4 mg/gtopicalThe Kroger Co.2014-01-182016-04-05Us
Blackhead Clearing Scruggel19.4 mg/gtopicalWal Mart2007-08-132016-04-05Us
Blemfreelotion.587 g/118mLtopicalEquibal, Inc.2014-08-012016-04-05Us
Blemish Clearing Facial Wipescloth10 mg/1topicalYes To Inc.2015-05-202016-04-05Us
Blemish Control Blotting Paperstrip.03 mg/1topicalNYX Los Angeles Inc.2011-12-152016-04-05Us
Blemish Control Face Primercream2 g/100mLtopicalJ. A. Cosmetics U.S. INC2015-01-272016-04-05Us
Blemish Correcting Serum Sensitivegel2 g/100mLtopicalCEN BEAUTY LLC2013-02-212016-04-05Us
Blemish Treatmentgel.02 g/gtopicalNeo Strata Company Inc2010-10-302016-04-05Us
Blistex Stridex Spot and T-zone Acne Cleargelgel2 g/100gtopicalBlistex Inc2016-01-042016-04-05Us
Body Washgel25 mg/mLtopicalTop Co Associates Llc2015-01-152016-04-05Us
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Shiseido Ibuki Multigel154 mg/30mLtopicalSHISEIDO AMERICAS CORPORATION2015-02-012016-04-05Us
Shiseido Pureness Anti-shine Refreshing Lotionlotion0.5 %topicalShiseido America Inc2003-11-012009-07-31Canada
Simicort - Crm 1.8%cream1.8 %topicalEnzymatic Therapy (Canada) Inc.1996-10-082000-07-11Canada
Skin Medica Purifying Foaming Washliquid20 mg/mLtopicalAllergan, Inc.2013-01-012016-04-23Us
Skin Perfecting Acne and Blemish Washrinse.5 mL/100mLtopicalBiocosmetics Research Labs2006-06-192016-04-05Us
Skin Purifying Wipesliquid.5 mg/mLtopicalDermalogica, Inc.2010-09-302016-04-05Us
Skinceuticals Blemish Plus Age Defense Acne Treatmentlotion15 mg/mLtopicalL'Oreal USA Products Inc2005-08-012016-04-05Us
Skinceuticals Clarifying Cleansercream20 mg/mLtopicalL'Oreal USA Products Inc2005-08-012016-04-05Us
Skinmedica Purifying Tonerliquid20 mg/mLtopicalAllergan, Inc.2013-01-012015-10-31Us
Skintx Medicated Acne Washliquid2 mL/100mLtopicalVivier Pharma, Inc.2011-01-192016-04-05Us
So Fresh So Clean Maximum Acne Treatmentcloth2 g/100gtopicalGlobal Beauty Care, Inc.2015-06-252016-04-05Us
So Fresh So Clean Mild Acne Treatmentcloth.5 g/100gtopicalGlobal Beauty Care, Inc.2015-06-252016-04-05Us
Softsheencarson Magic Bump Rescue Spot Treatmentlotion20 mg/mLtopicalL'Oreal USA Products Inc2013-11-012016-04-05Us
Soluver Enfants/kidssolution17 %topicalDermtek Pharma Inc2002-07-302004-06-30Canada
Solv Xshampoo18 mg/LtopicalMediceutical Laboratories, LTD1994-01-012016-04-05Us
Soothion Acne Treatment Formulalotion1 g/100gtopicalElectrolyzed Innovations, Llc2015-04-012016-04-05Us
Soothion Psoriasis and Seborrheic Dermatitis Formulalotion2 g/100gtopicalElectrolyzed Innovations, Llc2015-04-012016-04-05Us
Specific Beauty Clarifying Wash Acne Treatment Cleansersoap20 mg/mLtopicalSomabella Laboratories, LLC2011-05-062016-04-05Us
Spot Controlcream2.0 %topicalE Excel Llc2000-04-122005-08-03Canada
Spot Remover Acne Treatment Padsliquid.009506 g/100mLtopicalORIGINS NATURAL RESOURCES INC.2011-04-012016-04-05Us
Spot Repairing Serumcream.065 mg/13mLtopicalGOWOONSESANG COSMETICS CO., LTD.2012-10-012016-04-05Us
Spotless Cleanser Bioelementscream2 g/100mLtopicalBioelements, Inc.2013-06-172016-04-05Us
ST. Ives Blackhead Clearing Green Tea Scrubemulsion.01 g/mLtopicalConopco Inc. d/b/a Unilever2014-01-012016-04-05Us
ST. Ives Blemish and Blackhead Controlemulsion.02 g/gtopicalCosmetic Laboratories of America2011-02-232016-04-05Us
ST. Ives Blemish and Blackhead Controlemulsion.02 g/gtopicalAlberto Culver Usa Inc.2009-06-012016-04-05Us
ST. Ives Blemish and Blackhead Control Apricot Scrubemulsion.02 g/gtopicalConopco Inc. d/b/a Unilever2012-03-012016-04-05Us
ST. Ives Blemish and Blackhead Facialsoap.02 mL/mLtopicalAlberto Culver Usa Inc.2009-06-012016-04-05Us
ST. Ives Blemish and Blackhead Facial Washsoap.02 g/mLtopicalCosmetic Laboratories of America2011-02-282016-04-05Us
ST. Ives Blemish Control Green Tea Scrubemulsion.01 g/mLtopicalConopco Inc. d/b/a Unilever2013-06-152016-04-05Us
ST. Ives Body Scrub Naturally Clear Skin Green Teaemulsion.02 mL/mLtopicalCosmetic Laboratories of America2011-02-142016-04-05Us
ST. Ives Body Scrub Naturally Clear Skin Green Teaemulsion.02 mL/mLtopicalAlberto Culver Usa Inc.2011-02-142016-04-05Us
ST. Ives Body Wash Naturally Clear Skin Green Teasoap.02 mL/mLtopicalCosmetic Laboratories of America2011-02-142016-04-05Us
ST. Ives Body Wash Naturally Clear Skin Green Teasoap.02 mL/mLtopicalAlberto Culver Usa Inc.2011-02-142016-04-05Us
ST. Ives Green Tea Cleanseremulsion.02 mL/mLtopicalConopco Inc. d/b/a Unilever2012-03-082016-04-05Us
ST. Ives Green Tea Cleanseremulsion.02 g/mLtopicalConopco Inc. d/b/a Unilever2013-06-152016-04-05Us
ST. Ives Green Tea Scrubemulsion.01 mL/mLtopicalConopco Inc. d/b/a Unilever2012-03-082016-04-05Us
ST. Ives Medicated Apricot Daily Cleansing Clothsliquid2.2 %topicalAlberto Culver Canada Inc.2002-09-022005-07-05Canada
ST. Ives Naturally Clear Green Tea Facialsoap.02 mL/mLtopicalAlberto Culver Usa Inc.2010-01-312016-04-05Us
ST. Ives Naturally Clear Green Tea Facialsoap.01 mL/mLtopicalAlberto Culver Usa Inc.2010-01-312016-04-05Us
ST. Ives Naturally Clear Skin Green Tea Facialsoap.02 g/gtopicalAlberto Culver Usa Inc.2012-01-012016-04-05Us
Stay Pure Acne Treatmentlotion20 mg/mLtopicalAloette2015-01-012016-04-05Us
Stridex Conditioning Acne Scrubgel2 g/100mLtopicalBlistex Inc2012-12-312016-04-05Us
Stridex Essentialliquid1 g/100mLtopicalBlistex Inc2012-12-012016-04-05Us
Stridex Maximumliquid2 g/100mLtopicalBlistex Inc2012-12-012016-04-05Us
Stridex Naturally Clearliquid.1 g/1topicalBlistex Inc2009-11-232016-04-05Us
Stridex Sensitiveliquid.5 g/100mLtopicalBlistex Inc2012-12-012016-04-05Us
Super Spot Remover Acne Treatmentgel2 mL/100mLtopicalORIGINS NATURAL RESOURCES INC.2012-04-012016-04-05Us
Systeme Biolage Anti-dandruff Shampoo - 2%shampoo2 %topicalMatrix Essentials Inc.1996-11-221999-07-12Canada
T/gel Overnight Dandruff Treatmentsuspension2 %topicalJohnson & Johnson Inc2002-10-152005-08-09Canada
T/gel Shampooshampoo3 %topicalJohnson & Johnson Inc2003-02-102005-08-09Canada
Take Control Calming Cleansergel2 g/100mLtopicalmybody2012-09-272016-04-05Us
Ten-O-six Medicated Deep Pore Cleanserlotion2 %topicalBonne Bell Of Canada Ltd.1995-12-311999-07-07Canada
Ten-O-six Medicated Deep Pore Gel - 2%gel2 %topicalBonne Bell Of Canada Ltd.1995-12-311997-07-22Canada
Terrasil Psoriasis Therapy Maximum Strengthointment3 g/100gtopicalAidance Skincare & Topical Solutions, LLC2012-12-122016-04-05Us
Terrasil Wart Removalstick12 g/100gtopicalAidance Skincare & Topical Solutions, LLC2012-09-072016-04-05Us
Terrasil Wart Removal Maxstick15 g/100gtopicalAidance Skincare & Topical Solutions, LLC2012-09-072016-04-05Us
Thatzit Acne Treatmentlotion1 g/100gtopicalAidance Skincare & Topical Solutions, LLC2012-09-072016-04-05Us
Thatzit Acne Treatment Maxlotion2 g/100gtopicalAidance Skincare & Topical Solutions, LLC2012-09-072016-04-05Us
Therapeutic Dandruffshampoo30 mg/mLtopicalCVS Pharmacy, Inc2016-03-112016-04-05Us
Thicker Fuller Hair - Dandruff Sulfate Freeshampoo18 mg/mLtopicalGolden Sun DBA Newhall Laboratories2013-12-162016-04-05Us
Tonic Acne Clearing Treatmentliquid.0024 mg/.12mgtopicalCare Pluss Pharma S.A. De C.V.2012-08-062016-04-05Us
Ultimate Daily Face Washcream2 g/100mLtopicalDOLGENCORP INC.2013-07-202016-04-05Us
Ultimate Daily Face Washcream2 g/100mLtopicalEmilia Personal Care Inc.2014-01-102016-04-05Us
Unagelcream2 g/100gtopicalAdvanced Skin Technology, LLC2012-09-042016-04-05Us
Verruguingel17 g/100gtopicalWorld Perfumes, Inc2015-05-052016-04-05Us
Verruguingel17 g/100gtopicalCaribe Natural, Inc2015-05-052016-04-05Us
Verrustat Medicated Plantar Padspatch.4 g/100gtopicalClinical Therapeutic Solutions2013-10-162016-04-05Us
Verrustat Wart Removerliquid170 mg/mLtopicalClinical Therapeutic Solutions2013-10-162016-04-05Us
Verucide Physician Formulaliquid17 mL/10mLtopicalBlaine Labs Inc.2010-01-012016-04-05Us
Vichy Laboratoires Normaderm Beautifying Anti Acne Care 24 H Hydrating Acne Treatmentlotion15 mg/mLtopicalL'Oreal USA Products Inc2016-01-012016-04-05Us
Vichy Laboratoires Normaderm Daily Deep Cleansinggel5 mg/mLtopicalL'Oreal USA Products Inc2012-02-012016-04-05Us
Vichy Laboratoires Normaderm Daily Gentle Cleansercream5 mg/mLtopicalL'Oreal USA Products Inc2012-06-012016-04-05Us
Vichy Laboratoires Normaderm Daily Pore Unclogging Scrubgel5 mg/mLtopicalL'Oreal USA Products Inc2012-02-012016-04-05Us
Vichy Laboratoires Normaderm Hyaluspot Acne Treatmentlotion15 mg/mLtopicalL'Oreal USA Products Inc2015-07-012016-04-05Us
Vichy Laboratoires Normaderm Purifying Pore Tightening Tonerliquid5 mg/mLtopicalL'Oreal USA Products Inc2012-02-012016-04-05Us
Vichy Laboratoires Normaderm Triple Action 3 In 1 Cleansercream5 mg/mLtopicalL'Oreal USA Products Inc2012-06-012016-04-05Us
Vichy Laboratoires Normaderm Triple Action Anti Acne Hydratinglotion.5 mL/50mLtopicalLaboratoires Industriels de Vichy (LIDV)2011-03-012016-04-05Us
Vichy Laboratoires Normaderm Triple Action Antiacne Hydratinglotion10 mg/mLtopicalL'Oreal USA Products Inc2011-03-012016-04-05Us
Vichy Normaderm Daily Deep Cleansinggel1 mL/200mLtopicalLaboratoires Industriels de Vichy (LIDV)2012-02-012016-04-05Us
Vichy Normaderm Pore Unclogging Daily Scrubgel.625 mL/125mLtopicalLaboratoires Industriels de Vichy (LIDV)2012-02-012016-04-05Us
Vichy Normaderm Purifying Pore Tightening Tonerliquid1 mL/200mLtopicalLaboratoires Industriels de Vichy (LIDV)2012-02-012016-04-05Us
Vichy Normaderm Total Matlotion5 mg/mLtopicalL'Oreal USA Products Inc2013-02-012016-04-05Us
Viper Acne Body Washliquid2 mL/100mLtopicalCVS Pharmacy2011-03-182016-04-05Us
Vircin Advanced Wart Treatmentcream17 g/100gtopicalPure Source Inc.2014-06-122016-04-05Us
Virtual Claritylotion0.5 %topicalFlageoli Limited2003-07-082008-08-26Canada
Visco-gel Medicated Round Callus Removersdisc17.67 mg/1topicalPEDIFIX, INC.2013-06-012016-04-05Us
Vitale Sensitive Scalp 12 In 1 Instant Relief Anti Dandruff Sprayspray15 mg/mLtopicalJF Labs, Inc.2009-11-012016-04-05Us
Walgreens Corn Removerstrip4.42 mg/1topicalWALGREENS Co2013-06-012016-04-23Us
Walgreens Medicated Callus Removersdisc17.67 mg/1topicalWalgreens Co.2013-06-012016-04-23Us
Walgreens Oil-free Acne Washsolution2 g/100mLtopicalWalgreens Company2013-01-052016-04-23Us
Walgreens Pink Grapefruitliquid20 mg/mLtopicalWalgreen Company2013-12-172016-04-23Us
Wart Removerplaster40 mL/1topicalPharmaplast SAE2010-09-012016-04-05Us
Wart Remover Gelgel.17 g/gtopicalPremier Brands of America Inc.2013-01-012016-04-05Us
Wart Remover Liquidliquid.17 g/gtopicalPremier Brands of America Inc.2013-01-012016-04-05Us
Wartrol Wart Removerliquid2.51 mL/14.78mLtopicalPacific Naturals2011-09-012016-04-05Us
Well At Walgreens Pink Grapefruitliquid20 mg/mLtopicalWalgreen Company2015-12-082016-04-23Us
Well At Walgreens Pink Grapefruitliquid20 mg/mLtopicalWalgreen Company2013-12-312016-04-23Us
Well At Walgreens Ultimate Dailygel4 g/200gtopicalWalgreen Company2015-11-012016-04-23Us
Wet Wipesswab1 g/100gtopicalHangzhou Guoguang Touring Commodity Co., Ltd.2015-02-252016-04-05Us
Wet Wipesswab.5 g/100gtopicalHangzhou Guoguang Touring Commodity Co., Ltd.2015-02-252016-04-05Us
Wet Wipesswab.5 g/100gtopicalHangzhou Guoguang Touring Commodity Co., Ltd.2015-02-252016-04-05Us
Wet Wipesswab2 g/100gtopicalHangzhou Guoguang Touring Commodity Co., Ltd.2015-02-252016-04-05Us
X Out Cleansing Body Barsoap1 mg/100gtopicalGuthy Renker Llc2012-12-312016-04-05Us
X Out Daily Body Scrublotion2 g/100mLtopicalGuthy Renker Llc2012-12-312016-04-05Us
X Out Shine Controlcream.5 mg/mLtopicalGuthy Renker Llc2013-08-192016-04-05Us
Xtracare Dandruff Hair Washshampoo10 g/325gtopicalRejoice International2014-02-052016-04-05Us
Xtracare Dandruff Hair Washshampoo10 g/325gtopicalChina Ningbo Shangge Cosmetic Technology Corp.2014-02-052016-04-05Us
Xtracare Deep Cleaning Astringentgel5 mg/237mgtopicalRejoice International2013-11-262016-04-05Us
Yat Tip Torplaster40 g/1topical; transdermalGUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. BAIYUNSHAN HEJIGONG PHARMACEUTICAL FACTORY2004-04-262016-04-05Us
Yat Tip Xiaoplaster156 mg/1topicalInternationa Nature Nutraceuticals, Inc1977-01-012016-04-05Us
Yes To Tomatoesliquid5.3 g/265mLtopicalBentley Laboratories, LLC2014-09-042016-04-05Us
Yes To Tomatoes Acne Clearing Facial Tonerliquid5 mg/mLtopicalYes To Incorporated2015-06-112016-04-05Us
Yes To Tomatoes Acne Control Gel Cleansergel1 g/100mLtopicalAutumn Harp, Inc.2011-10-272016-04-05Us
Yes To Tomatoes Clear Skin Corrective Concealer Light Tintstick1 g/100gtopicalAutumn Harp Incorporated2014-12-152016-04-05Us
Yes To Tomatoes Daily Pore Scrubcream2 g/100gtopicalAutumn Harp, Inc.2011-01-132016-04-05Us
Yes To Tomatoes Daily Repair Treatmentgel1 mg/100mLtopicalAutumn Harp, Inc.2013-04-112016-04-05Us
Yes To Tomatoes Detoxifying Charcoal Cleansercream10 mg/mLtopicalYes To Incorporated2015-06-092016-04-05Us
Yes To Tomatoes Detoxifying Charcoal Mud Maskcream5 mg/mLtopicalYes To Incorporated2015-06-112016-04-05Us
Yes To Tomatoes Roller Ball Spot Sticksolution2 mg/100mLtopicalAutumn Harp, Inc.2011-01-122016-04-05Us
Ys Solution Ac Carecream.47 mL/100mLtopicalAjou Medics Co., Ltd2011-08-102016-04-05Us
Ys Solution Ac Control Skin Regular Mildliquid.47 mL/100mLtopicalAjou Medics Co., Ltd2011-08-102016-04-05Us
Ys Solution Ac Control Skin Regular Mildliquid.47 mL/100mLtopicalAjou Medics Co., Ltd2011-10-252016-04-05Us
Ys Solution Intensive Ac Caregel.47 mL/100mLtopicalAjou Medics Co., Ltd2011-08-102016-04-05Us
Zap-IT - Crm - 2.0%cream2 %topicalMelaleuca Of Canada Inc.1996-07-162000-07-27Canada
Zit Erasercream1 g/100gtopicalJ. A. Cosmetics U.S. INC2013-10-102016-04-05Us
Zit Zappercream1 g/100gtopicalJ. A. Cosmetics U.S. INC2013-10-102016-04-05Us
Zo Medical Aknebright Acne Spot and Pigmentation Treatmentgel20 mg/mLtopicalZO Skin Health, Inc.2014-11-032016-04-05Us
Zo Medical Cebatrol Oil Control Pads Acne Treatmentsolution20 mg/mLtopicalZO Skin Health, Inc.2015-04-012016-04-05Us
Zo Skin Health Gsr (getting Skin Ready) SystemkitZO Skin Health, Inc.2011-01-012016-04-05Us
International Brands
NameCompany
Compound WNot Available
Dr. Scholl's Callus RemoversNot Available
Dr. Scholl's Corn RemoversNot Available
Dr. Scholl's Wart Remover KitNot Available
Duofil Wart RemoverNot Available
DuoplantNot Available
Ionil Plus shampooNot Available
SalonilNot Available
SalsoninNot Available
StridexNot Available
Brand mixtures
NameLabellerIngredients
Acne Clearning Treatment FaceCare Pluss Pharma S.A. De C.V.
Acne Treatment SystemVivier Canada Incorporated
ActikerallCipher Pharmaceuticals Inc
Adasept Acne GelOdan Laboratories Ltd
Anti-acne Formula for MenClinique Laboratories Dist
Anti-acne Formula-lightClinique Laboratories Dist
Anti-acne Formula-mediumClinique Laboratories Dist
Antidouleurs RezallProduits Francais Labs Inc.
Atomy Hair TreatmentAtomy Co., Ltd.
Atomy Herbal Hair TonicAtomy Co Ltd
Azo Urinary Tract Defense Antibacterial ProtectionI Health, Inc.
British Army Foot PwrRegal Pharms, Division Of Bradcan Corporation
Cellapy HaircellGm Holdings Co., Ltd
Cellapy Haircell Meso TonicGm Holdings Co., Ltd
Clean and Clear Advantage Acne ControlJohnson & Johnson Consumer Inc.
Cleansing Foaming Gel Acne Pro SkinLange SAS
Clear Cell Medicated AcneAllure Labs, Inc.
Clear Cell Salicylic Clarifying TonicAllure Labs, Inc.
Clear Proof Acne SystemMary Kay Inc.
Clear Proof Acne System The Go SetMary Kay Inc.
Clearasil Ultra Acne SystemReckitt Benckiser LLC
Clearasil Ultra Fast Fix AcneReckitt Benckiser LLC
Clearasil Ultra Rapid Action Acne SystemReckitt Benckiser LLC
Clearasil Ultra Rapid Action Clear SkinReckitt Benckiser LLC
Clenziderm M.D. System Acne Therapeutic SystemValeant Pharmaceuticals North America LLC
Clenziderm Normal To Oily Skin Acne Therapeutic SystemOMP, INC.
ClerianClerian, Inc.
Clerian Anti-hairlossClerian, Inc.
Clerian HClerian, Inc.
Cuplex GelTrans Canaderm Inc.
Cystex PlusDse Healthcare Solutions, Llc
Denovo 3 HEcomine Co., Ltd.
Dermoscribe PsoriasisDermoscribe Pty Ltd
Dermoscribe Seborrheic DermatitisDermoscribe Pty Ltd
DiprosalicMerck Canada Inc
Dr. Babor Purity Cellular Ultimate Blemish Reducing DuoBabor Cosmetics America, Corp.
Easter Scalp TonicWecosmetics Co.
EcosomEcosom.Co.,Ltd.
Ecosom TonicEcosom.Co.,Ltd.
Erase It Kitmybody
FinaftaEfficient Laboratories Inc.
Formule L2Herbages Naturbec LtÉe.
Freezone LiqWhitehall Robins Inc.
Gmc Medical Acne TreatmentLaboratoires Dermo Cosmetik Inc
Haircop Hairdanbi NaturalThe Nature Co., Ltd.
Hasol Anti Hair Loss Day TonicEcomine Co., Ltd.
Hasol Intensive Scalp TonicEcomine Co., Ltd.
Hesol RimEcomine Co Ltd
Hesol Rim Jean-aeck Hair TonicEcomine Co Ltd
Hesol Rim TonicEcomine Co Ltd
Ionil ShampooGalderma Canada Inc
Jason Dandruff Relief TreatmentThe Hain Celestial Group, Inc
Kerasal Topical SolutionSpectropharm Dermatology, A Division Of Draxis Health Inc.
Lancell Hair Loss Prevention Hair Grower TonicMicell Bio Co., Ltd
Lassar's PasteRougier Pharma Division Of Ratiopharm Inc
Lassar's PstDawson Traders Ltd.
LocasalenNovartis Pharmaceuticals Canada Inc
Mazon Medicated CreamDannorth Natural Laboratories Inc
Mazon Medicated ShampooDannorth Natural Laboratories Inc
Medi-dan ShampooMahdeen Mediceuticals Ltd
Methenamine and Sodium SalicylateAmol Pharmaceuticals Private Limited
Ndm Scalp TonicDamomedical Ltd.
Neutrogena Complete Acne Therapy SolutionJohnson & Johnson Consumer Inc.
Neutrogena Complete Acne Therapy SystemNeutrogena Corporation
Notamo Hair TonicHello International
ObagiYS PLUS CORPORATION
Oxipor LotionWhitehall Robins Inc.
P&s PlusPendopharm Division Of De Pharmascience Inc
Panoxyl Clear Acne Cleansing GelGlaxosmithkline Inc
Paula's Choice Clear Anti-acne Extra Strength SystemPaula's Choice Llc
Paula's Choice Clear Anti-acne Regular Strength SystemPaula's Choice Llc
Pazol XsStratus Pharamceuticals, Inc
Pernox CrmWestwood Squibb, Division Of Bristol Myers Squibb Canada Inc.
Pernox Crm LemonWestwood Squibb, Division Of Bristol Myers Squibb Canada Inc.
Phs Hair Science Fem Hair Loss TonicRevamp International Pte. Ltd.
Phs Hair Science Hom Hair Loss TonicRevamp International Pte. Ltd.
Phs Hair Science Pro Hair Loss TonicRevamp International Pte. Ltd.
Plax Anti-plaque Dental RinseJohnson & Johnson Inc
Premium NotamoHello International
Psoricare Crm 3%Avacare, Division Of Jeunique International Inc.
Ratio-topisalicTeva Canada Limited
SalinocaineMedical Products Laboratories, Inc.
Sastid Soap for Stubborn AcneStiefel Canada Ulc
Savex With PabaSabex Inc
Savex With Sunscreen OntSabex Inc
Scal-tonic Intensive Liquid Hair CareDoori Cosmetics Co., Ltd
Scalpicin Anti-dandruff Anti-itch LiquidCombe Incorporated
Sebcur-TDermtek Pharma Inc
SebexRugby Laboratories
Sebulex LiqWestwood Squibb, Division Of Bristol Myers Squibb Canada Inc.
Sebutone ShampooWestwood Squibb, Division Of Bristol Myers Squibb Canada Inc.
Simmyungsaengmosu Hair TonicSimmyung Pharmaceutical Co Ltd
Skintx Acne Treatment SystemVivier Pharma
Sterex Crm PlusInternational Dermatologicals Inc.
Sterex Lot PlusInternational Dermatologicals Inc.
Sterex ShpInternational Dermatologicals Inc.
Super Bump ReliefElements Personal Care, Inc.
Tardan ShpOdan Laboratories Ltd
Targel SaOdan Laboratories Ltd
Theraphytion Nokmosu360 Perspective
Therapro Exfoliating Dandruff Treatment ShampooCanmax Laboratories Inc.
Therapytion Hair Tonic360 Perspective
Therapytion Nokmosu Hair TonicTherapytion Co., Ltd.
Thomas Formula No 17Thomas Hair And Scalp Specialists
Thomas Formula No 47Thomas Hair And Scalp Specialists
Tiacid SolutionMerit Industries Inc.
X-seb Plus Conditioning ShampooPharmascience Inc
X-seb T Plus Conditioning ShampooPharmascience Inc
X-seb T ShampooPharmascience Inc
X-tar ShampooDormer Laboratories Inc.
Yat Tip XiaoHuangshi Hygenic Material Pharmacy Co. Ltd.
Salts
Name/CASStructureProperties
Sodium salicylate
54-21-7
Thumb
  • InChI Key: ABBQHOQBGMUPJH-UHFFFAOYSA-M
  • Monoisotopic Mass: 160.013638701
  • Average Mass: 160.1026
DBSALT001552
Categories
UNIIO414PZ4LPZ
CAS number69-72-7
WeightAverage: 138.1207
Monoisotopic: 138.031694058
Chemical FormulaC7H6O3
InChI KeyInChIKey=YGSDEFSMJLZEOE-UHFFFAOYSA-N
InChI
InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
IUPAC Name
2-hydroxybenzoic acid
SMILES
OC(=O)C1=CC=CC=C1O
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as salicylic acids. These are ortho-hydroxylated benzoic acids.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassBenzoic acids and derivatives
Direct ParentSalicylic acids
Alternative Parents
Substituents
  • Salicylic acid
  • Benzoic acid
  • Benzoyl
  • Phenol
  • Vinylogous acid
  • Monocarboxylic acid or derivatives
  • Carboxylic acid
  • Carboxylic acid derivative
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Pharmacology
IndicationKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
PharmacodynamicsSalicylic acid treats acne by causing skin cells to slough off more readily, preventing pores from clogging up. This effect on skin cells also makes salicylic acid an active ingredient in several shampoos meant to treat dandruff. Use of straight salicylic solution may cause hyperpigmentation on unpretreated skin for those with darker skin types (Fitzpatrick phototypes IV, V, VI), as well as with the lack of use of a broad spectrum sunblock. Subsalicylate in combination with bismuth form the popular stomach relief aid known commonly as Pepto-Bismol. When combined the two key ingredients help control diarrhea, nausea, heartburn, and even gas. It is also very mildly anti-biotic.
Mechanism of actionSalicylic acid directly and irreversibly inhibits the activity of both types of cyclo-oxygenases (COX-1 and COX-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. Salicylate may competitively inhibit prostaglandin formation. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. It works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. Salicylic acid is also used as an active ingredient in gels which remove verrucas (plantar warts). Salicylic acid inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with nicotinamide adenosine dinucleotide (NAD) and noncompetitively with UDPG. It also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid (UDPGA) to the phenolic acceptor. The wound-healing retardation action of salicylates is probably due mainly to its inhibitory action on mucopolysaccharide synthesis.
Related Articles
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityOral rat LD50: 891 mg/kg. Inhalation rat LC50: > 900 mg/m3/1hr. Irritation: skin rabbit: 500 mg/24H mild. Eye rabbit: 100 mg severe. Investigated a mutagen and reproductive effector.
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Salicylic Acid Action PathwayDrug actionSMP00709
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9756
Blood Brain Barrier+0.6165
Caco-2 permeable+0.8867
P-glycoprotein substrateNon-substrate0.734
P-glycoprotein inhibitor INon-inhibitor0.9815
P-glycoprotein inhibitor IINon-inhibitor0.9937
Renal organic cation transporterNon-inhibitor0.9167
CYP450 2C9 substrateNon-substrate0.7962
CYP450 2D6 substrateNon-substrate0.9233
CYP450 3A4 substrateNon-substrate0.766
CYP450 1A2 substrateNon-inhibitor0.9517
CYP450 2C9 inhibitorNon-inhibitor0.7984
CYP450 2D6 inhibitorNon-inhibitor0.9659
CYP450 2C19 inhibitorNon-inhibitor0.7644
CYP450 3A4 inhibitorNon-inhibitor0.8675
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.8525
Ames testNon AMES toxic0.9829
CarcinogenicityNon-carcinogens0.8627
BiodegradationReady biodegradable0.8086
Rat acute toxicity2.2160 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9631
hERG inhibition (predictor II)Non-inhibitor0.9734
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Geltopical.6 g/120mL
Creamtopical.001 mg/10mL
Liquidtopical.1 mg/100mL
Solutiontopical22.5 mg/15mL
Creamtopical14 g/100g
Creamtopical.5 g/100g
Geltopical7 mg/354mg
Geltopical.02158 g/100mL
Liquidtopical.02 g/1
Liquidtopical29.2 mg/1
Liquidtopical.75 mg/150mL
Geltopical0.5 %
Geltopical1.5 g/100mL
Geltopical21 mg/mL
Geltopical.01 g/g
Solutiontopical.2 g/40g
Liquidtopical1.5 mL/100mL
Soaptopical2 g/100g
Lotiontopical1 mL/100mL
Creamtopical1 mL/100mL
Geltopical.5 mL/100mL
Liquidtopical.5 g/.5mL
Geltopical.005 mg/g
Geltopical5 mg/g
Kit; liquid; lotiontopical
Swabtopical.5 g/100g
Swabtopical5 mg/1000mg
Swabtopical5 mg/mL
Lotiontopical.02 mL/mL
Clothtopical5 mg/1
Spraytopical2.84 g/142g
Solutiontopical20 mg/1
Lotiontopical10 mg/mL
Geltopical.6 g/30mL
Lotiontopical1 mg/mL
Creamtopical1.5 %
Creamcutaneous.3 mL/15mL
Patchtopical2 mg/100mg
Plastertopical.4 1/1001
Plastertopical40 1/1
Aerosol, foamtopical1.5 g/100g
Clothtopical2 g/101
Clothtopical2 g/301
Geltopical.5 %
Powdertopical0.6 %
Striptopical1.4 %
Liquid; padtopical.5 %
Liquidtopical.5 %
Lotiontopical250 g/5g
Shampootopical200 g/6g
Creamtopical50 g/g
Creamtopical.08 g/20mL
Creamtopical5 mg/g
Liquidtopical5 mg/mL
Geltopical15 uL/mL
Swabtopical10 uL/mL
Jellytopical1 %
Rinsetopical2 g/397g
Shampootopical2 g/414g
Disctopical20 mg/1
Sticktopical2 g/100g
Creamtopical5 mL/100mL
Shampootopical20 mg/mL
Liquid
Lotiontopical.75 mg/150mL
Lotiontopical1.1 mL/100mL
Clothtopical20 mg/mL
Clothtopical.5 g/100g
Creamtopical.5 mL/100mL
Lotiontopical2 mL/100mL
Soap bartopical0.50 %
Soaptopical.5 g/100g
Clothtopical6 mg/1
Soap bartopical.5 %
Soaptopical5 mg/g
Lotiontopical0.7 %
Sticktopical2 %
Lotiontopical1.5 %
Liquidtopical1.5 %
Padtopical40 %
Emulsiontopical10 mg/g
Ointmenttopical30 mg/g
Geltopical2 g/100mL
Solutiontopical.5 g/100mL
Kit
Lotiontopical1 %
Shampootopical.24 mg/355mL
Ointmenttopical2.8 g/140g
Geltopical1.8 %
Geltopical2 mL/100mL
Liquidtopical4.3 g/200mL
Liquidtopical4.56 g/236mL
Liquidtopical2.8 g/141g
Liquidtopical2.54 g/127g
Geltopical19.4 mg/g
Lotiontopical.587 g/118mL
Clothtopical10 mg/1
Striptopical.03 mg/1
Geltopical.02 g/g
Geltopical2 g/100g
Geltopical25 mg/mL
Powdertopical
Geltopical.4 g/20g
Ointmenttopical5 g/g
Patchtopical.19 mg/1
Patchtopical11.9 mg/21
Plastertopical40 %
Lotiontopical.5 g/59g
Liquidtransdermal
Creamtopical20.6 mg/mL
Liquidtopical10 mg/mL
Creamtopical.156 g/8.9mL
Creamtopical.28 g/14g
Liquidtopical.623 g/130mL
Liquidtopical.691 g/133mL
Pastetopical5 mg/g
Solutiontopical10 mg/mL
Geltopical2 g/151mL
Geltopical30 mg/mL
Lotiontopical
Creamtopical50 mg/mL
Liquidtopical50 mg/mL
Geltopical1 g/100g
Kittopical
Creamtopical.6 mL/60mL
Liquidtopical2.4 mL/240mL
Clothtopical283.5 mg/56.7g
Lotiontopical.0053 g/100mL
Lotiontopical.0091 g/100mL
Liquidtopical2.00 %
Geltopical2 %
Solutiontopical2 g/100g
Lotiontopical.01 g/g
Swabtopical2 g/100mL
Solutiontopical.03 g/1
Solutiontopical.01 g/1
Solutiontopical.015 g/1
Lotiontopical1 g/100mL
Solutiontopical1 g/100mL
Liquidtopical2 %
Lotiontopical150 mL/mL
Solutiontopical.02 g/1
Geltopical10 g/.2g
Creamtopical50 g/.5g
Liquidtopical5 mL/250mL
Pastetopical5 mg/mL
Lotiontopical.6 mL/30mL
Liquidtopical300 mg/30g
Creamtopical1.5 mL/75mL
Geltopical.022 mL/1.1mL
Creamtopical1 mL/50mL
Geltopical.375 mL/75mL
Lotiontopical5 mg/mL
Geltopical5 mg/mL
Geltopical.3 mL/15mL
Kit
Solutiontopical20 mg/mL
Sticktopical2 g/2mL
Spraytopical2 %
Liquidtopical1 %
Creamtopical1 %
Geltopical1 %
Powdertopical.5 g/100g
Geltopical17 %
Liquidtopical20 %
Plastertopical4 mg/1
Liquidtopical30 %
Creamtopical2 1/100g
Emulsiontopical.24 mg/29.6mg
Emulsiontopical1.89 mg/237mg
Plastertopical40 mg/1
Ointmenttopical15 %
Creamtopical1 g/100g
Geltopical.3 mg/30mL
Sticktopical.025 g/2.5g
Geltopical.1425 g/30mL
Liquidtopical2 mg/30mg
Patchtopical40 mg/1
Soaptopical20 mg/g
Liquidtopical3 g/100mL
Liquidtopical20.5 mg/mL
Tabletoral
Solutiontopical2.4 mL/120mL
Lotiontopical.015 g/g
Liquidtopical17.64 mg/mL
Lotiontopical.5 %
Liquidtopical20 mg/g
Lotiontopical10 uL/mL
Liquidtopical7.08 mL/236mL
Lotiontopical2.36 mL/118mL
Geltopical3 %
Geltopical3.54 mL/118mL
Creamtopical3 g/100g
Liquidtopical.5 g/100g
Liquidtopical50.5 mg/2.5mL
Lotiontopical30 mg/1.5mL
Shampootopical3.0 %
Soaptopical4.8 g/240g
Tabletoral325 mg
Tablet500 mg
Tablet325 mg
Geltopical1 g/50mL
Creamtopical1.5 g/50mL
Creamtopical.5 g/100mL
Liquidtopical12.64 %
Disctopical.4 g/1
Solutiontopical150 mg/mL
Solutiontopical1.7 mg/mL
Disctopical4 mg/1
Lotiontopical20 mg/g
Liquidtopical.48 mL/100mL
Liquidcutaneous.5 mg/100mg
Creamcutaneous.5 mg/100mg
Geltopical11 %
Liquidtopical150.28 mg/mL
Powdertopical1 g/100g
Pastetopical2 g/100g
Liquidtopical1 g/100g
Sticktopical2 g/100mL
Lotiontopical1 mg/g
Geltopical20 g/1000mL
Pastetopical20 mg/mL
Liquidtopical170 mL/mL
Liquidtopical40 mg/1
Patchtopical40 mg/100mg
Liquidoral
Soap bartopical2 %
Creamtopical2 %
Liquidtopical2.16 mg/120mL
Oiltopical.01 mL/mL
Shampootopical11.52 mL/384mL
Spraytopical20 mg/mL
Solutiontopical4.8 g/240mL
Aerosol, foamtopical.5 mL/100mL
Liquidtopical4 mL/200mL
Geltopical21.2 mg/100mL
Liquidtopical3 g/100g
Geltopical2.0 %
Solutiontopical1 mg/200mL
Spraytopical
Shampootopical.1 1/300mL
Liquidtopical3 %
Geltopical
Shampootopical1.8 mL/100mL
Lotiontopical1.184 mL/59.2mL
Liquidtopical.003 mL/mL
Liquidtopical.0001 mL/mL
Cream3 %
Liquidtopical20 mL/L
Liquidtopical.02 mL/mL
Geltopical.02 mL/mL
Shampootopical.5 g/100mL
Creamtopical0.5 %
Jellytopical.5 %
Creamtopical.5 %
Geltopical6 g/100g
Shampootopical5 g/100mL
Shampootopical6 g/92.6mL
Geltopical6 %
Creamtopical2 mCi/100mL
Solutiontopical5 mg/mL
Lotiontopical.45 mL/30mL
Pastetopical
Suspension; creamtopical0.5 %
Spraytopical4.72 mL/118mL
Clothtopical.6 mL/60mL
Geltopical.75 mL/50mL
Geltopical.425 mL/25mL
Pastetopical.75 mL/150mL
Sticktopical36 mg/1.8g
Liquidtopical.75 %
Plastertopical.4 g/g
Liquidtopical17 mg/100mg
Swabtopical.02 mL/1
Geltopical19.8 mg/g
Disctopical40 %
Shampootopical1.8 g/100mL
Plastertopical40 g/100g
Shampootopical2 g
Shampootopical.03 g/g
Creamtopical2.016 g/112g
Lotiontopical30 mg/mL
Solutiontopical.15 mg/30mL
Clothtopical1 g/100g
Shampootopical.2 1/300g
Ointmenttopical40 %
Liquidtopical.06 g/mL
Shampootopical.06 g/mL
Creamtopical30 mL/100mL
Liquidtopical1 mL/100mL
Swabtopical2 mL/100mL
Geltopical1 mg/g
Creamtopical1 mg/g
Spraytopical5 mg/mL
Geltopical20 mg/mL
Liquidtopical1.8 %
Creamtopical20 mg/mL
Clothtopical20 mg/1
Suspensiontopical20 mg/mL
Lotiontopical20 mg/mL
Lotiontopical2.0 %
Creamtopical5.5 mg/g
Geltopical1.5 %
Creamtopical1.0 %
Powdertopical5 mg/g
Shampootopical30 mg/mL
Ointmenttopical2 g/100g
Geltopical3 mg/15mL
Geltopical.1 g/20mL
Soaptopical.01 g/g
Clothtopical.02 g/g
Clothtopical.05 mg/100mg
Lotiontopical5 g/1000mL
Geltopical5 g/1000mL
Solution, gel forming / dropstopical20 mg/mL
Shampootopical9 mg/500g
Liquidtopical170 mg
Clothtopical20.5 mg/mL
Liquidtopical2.5 g/125g
Lotiontopical20.6 mg/mL
Creamtopical2 g/100g
Geltopical3 g/150g
Geltopical4 mg/177mg
Creamtopical.5 mL/50mL
Geltopical1.15 mL/115mL
Geltopical.06 mL/15mL
Patchtopical.4 g/g
Swabtopical20 mg/1
Swabtopical5 mg/1
Suspensiontopical0.5 %
Geltopical10 mg/mL
Lotiontopical2 %
Padtopical2 %
Padtopical.5 %
Creamtopical20 mg/g
Lotiontopical2 g/100mL
Plastertopical.4 g/1
Solution; kit; lotiontopical
Patchtopical4 mg/1
Creamtopical1 mg/20mg
Liquidtopical.025 g/1
Creamtopical15 mg/mL
Concentratetopical2 g/100mL
Liquidtopical.7 %
Geltopical20 mg/g
Creamtopical.02 g/mL
Liquiddental
Geltopical1 mL/100mL
Geltopical1 g/100mL
Creamtopical29 mL/100mL
Geltopical.008776 g/mL
Lotiontopical1.8 mg/180mg
Creamtopical1 mg/100mL
Clothtopical.036 g/1
Creamtopical.02 g/1000mL
Lotiontopical2 mg/100mL
Lotiontopical1 mg/100mL
Geltopical5 mg/1000mL
Lotiontopical.5 g/100mL
Solutiontopical5 mg/1000mL
Liquidtopical2 mg/100mL
Lotiontopical.5 mg/100mL
Geltopical.5 g/100mL
Lotion/shampootopical.02 g/1000mL
Geltopical.5 mg/100mL
Soaptopical1 g/100g
Creamtopical1.5 g/100g
Liquidtopical0.5 %
Lotiontopical0.5 %
Padtopical0.5 %
Creamtopical2.26 g/113g
Creamtopical1.1 g/56.7g
Soaptopical3 g/100g
Shampootopical3 g/100g
Creamtopical2.5 g/100g
Creamtopical3 g/100mL
Liquidtopical1.8 g/100mL
Lotiontopical.5 mL/100mL
Creamtopical17 g/100g
Liquidtopical2 mg/mL
Spraytopical4.8 mL/240mL
Creamtopical2 mL/100mL
Sticktopical1 %
Swabtopical21 mg/1
Liquidtopical2 mL/100mL
Liquidtopical170 mg/mL
Creamtopical24 g/400g
Lotiontopical24.84 mg/414mL
Creamtopical60 mg/g
Lotiontopical60 mg/mL
Shampootopical60 mg/mL
Geltopical1.2 g/60g
Aerosol, foamtopical6 g/100g
Creamtopical27.24 g/g
Creamtopical6 g/100g
Geltopical.17 g/g
Geltopical.17 g/7g
Geltopical.21 g/1.25g
Geltopical60 mg/g
Liquidtopical.17 mg/9.8mL
Liquidtopical.17 g/9.8mL
Liquidtopical.17 mg/151mL
Liquidtopical.17 g/g
Liquidtopical.17 mg/15mL
Liquidtopical.17 g/9mL
Liquidtopical2.1 g/14.7mL
Liquidtopical260 mg/mL
Liquidtopical275 mg/mL
Lotiontopical.5 g/60mL
Lotiontopical6 mL/100mL
Lotiontopical60 mg/g
Patchtopical40 mg/141
Patchtopical40 mg/91
Patchtopical40 mg/61
Patchtopical40 mg/181
Patchtopical40 mg/241
Patchtopical40 mg/41
Plastertopical.4 g/141
Plastertopical.4 g/1411
Plastertopical40 mg/141
Shampootopical6 mL/100mL
Shampootopical6 mg/100mL
Striptopical40 mg/1
Soap bartopical3.5 %
Liquidtopical.02 mg/mL
Liquidintravenous570 mg
Ointmenttopical
Geltopical15 mg/mL
Aerosol, foamtopical3.88 g/70g
Soap bartopical
Liquidtopical12 g/100mL
Liquidtopical30 mg/g
Liquidtopical17 %
Shampootopical
Pastetopical1 g/100g
Liquid; shampootopical
Shampootopical.03 g/mL
Liquidtopical.5 mL/100mL
Liquid0.5 %
Geltopical154 mg/30mL
Creamtopical1.8 %
Liquidtopical
Liquidtopical20 mg/mL
Rinsetopical.5 mL/100mL
Liquidtopical.5 mg/mL
Lotiontopical15 mg/mL
Kittopical
Clothtopical2 g/100g
Solutiontopical17 %
Shampootopical18 mg/L
Soaptopical20 mg/mL
Creamtopical2.0 %
Liquidtopical.009506 g/100mL
Creamtopical.065 mg/13mL
Emulsiontopical.02 g/g
Soaptopical.02 mL/mL
Soaptopical.02 g/mL
Emulsiontopical.01 g/mL
Emulsiontopical.02 mL/mL
Emulsiontopical.02 g/mL
Emulsiontopical.01 mL/mL
Liquidtopical2.2 %
Soaptopical.01 mL/mL
Soaptopical.02 g/g
Liquidtopical1 g/100mL
Liquidtopical2 g/100mL
Liquidtopical.1 g/1
Liquidtopical.5 g/100mL
Creamtopical
Shampootopical2 %
Suspensiontopical2 %
Shampootopical3 %
Ointmenttopical3 g/100g
Sticktopical12 g/100g
Sticktopical15 g/100g
Lotiontopical1 g/100g
Lotiontopical2 g/100g
Shampootopical18 mg/mL
Solutiontopical
Liquidtopical.0024 mg/.12mg
Plaster15 %
Creamtopical2 g/100mL
Solutiontopical285 mg/mL
Geltopical17 g/100g
Patchtopical.4 g/100g
Liquidtopical17 mL/10mL
Creamtopical5 mg/mL
Lotiontopical.5 mL/50mL
Geltopical1 mL/200mL
Geltopical.625 mL/125mL
Liquidtopical1 mL/200mL
Solutiontopical275 mg/mL
Spraytopical15 mg/mL
Striptopical4.42 mg/1
Disctopical17.67 mg/1
Solutiontopical2 g/100mL
Plastertopical40 mL/1
Liquidtopical2.51 mL/14.78mL
Geltopical4 g/200g
Swabtopical1 g/100g
Swabtopical2 g/100g
Soaptopical1 mg/100g
Creamtopical.5 mg/mL
Shampootopical10 g/325g
Geltopical5 mg/237mg
Plastertopical; transdermal40 g/1
Plastertopical
Plastertopical156 mg/1
Liquidtopical5.3 g/265mL
Sticktopical1 g/100g
Geltopical1 mg/100mL
Creamtopical10 mg/mL
Solutiontopical2 mg/100mL
Creamtopical.47 mL/100mL
Liquidtopical.47 mL/100mL
Geltopical.47 mL/100mL
Prices
Unit descriptionCostUnit
Keralyt scalp complete kit67.8USD kit
Keralyt 6% Gel 100 gm Tube51.99USD tube
Keralyt 6% Gel 40 gm Tube49.99USD tube
Compound W 17% Liquid 9.3ml Bottle11.99USD bottle
Keralyt 3% Gel 28.4 gm Tube11.35USD tube
Sastid soap4.32USD each
Salicylic acid 6% gel1.14USD g
Salactic film solution0.74USD ml
Compound w pads0.5USD each
Keralyt 6% gel0.5USD g
Freezone corn-callus liquid0.42USD ml
Keralyt 3% gel0.39USD g
Salicylic acid 6% shampoo0.21USD ml
Ionil plus 2% shampoo0.05USD ml
Ionil t plus shampoo0.05USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point158 °CPhysProp
boiling point211 °C at 2.00E+01 mm HgPhysProp
water solubility2240 mg/L (at 25 °C)YALKOWSKY,SH & DANNENFELSER,RM (1992)
logP2.26HANSCH,C ET AL. (1995)
logS-1.82ADME Research, USCD
Caco2 permeability-4.79ADME Research, USCD
pKa2.97SERJEANT,EP & DEMPSEY,B (1979)
Predicted Properties
PropertyValueSource
Water Solubility11.3 mg/mLALOGPS
logP1.96ALOGPS
logP1.98ChemAxon
logS-1.1ALOGPS
pKa (Strongest Acidic)2.79ChemAxon
pKa (Strongest Basic)-6.3ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area57.53 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity35.3 m3·mol-1ChemAxon
Polarizability12.81 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Download (8.17 KB)
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-MS (2 TMS)splash10-cvz0000000-62eae168a9d7ab3ada6fView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Negative (Annotated)splash10-zq00000000-54545731fceee84be340View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Negative (Annotated)splash10-zk00000000-2f1c989b672669aaf083View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Negative (Annotated)splash10-z300000000-a0049e982e8ecd7ab730View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negativesplash10-1z00000000-f1e71df6894bcc8dda74View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negativesplash10-z900000000-f9fd317c182ec7ca90dcView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negativesplash10-z000000000-2b17aea4ee0ddd6321cfView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negativesplash10-z000000000-320b7cd879b61439cf42View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negativesplash10-z000000000-7d1b96d60026076a7eccView in MoNA
MSMass Spectrum (Electron Ionization)splash10-zn00000000-6d4a0ff2d48d814b5c54View in MoNA
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,1H] 2D NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

Howard Jones, Robert W. Houser, “Process for preparing 4-(2,4-difluorophenyl)-salicyclic acid.” U.S. Patent US4225730, issued August, 1972.

US4225730
General References
  1. Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. [PubMed:5284360 ]
  2. Flower R, Gryglewski R, Herbaczynska-Cedro K, Vane JR: Effects of anti-inflammatory drugs on prostaglandin biosynthesis. Nat New Biol. 1972 Jul 26;238(82):104-6. [PubMed:4505422 ]
External Links
ATC CodesD01AE12N02BA04S01BC08
AHFS Codes
  • 24:16.00
  • 28:08.04.24
  • 84:28.00
  • 92:02.00*
PDB EntriesNot Available
FDA labelNot Available
MSDSNot Available
Interactions
Drug InteractionsNo interactions found.
Food InteractionsNot Available

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Prostaglandin-endoperoxide synthase activity
Specific Function:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the gener...
Gene Name:
PTGS1
Uniprot ID:
P23219
Molecular Weight:
68685.82 Da
References
  1. Moon C, Ahn M, Jee Y, Heo S, Kim S, Kim H, Sim KB, Koh CS, Shin YG, Shin T: Sodium salicylate-induced amelioration of experimental autoimmune encephalomyelitis in Lewis rats is associated with the suppression of inducible nitric oxide synthase and cyclooxygenases. Neurosci Lett. 2004 Feb 12;356(2):123-6. [PubMed:14746879 ]
  2. Graham GG, Scott KF: Mechanisms of action of paracetamol and related analgesics. Inflammopharmacology. 2003;11(4):401-13. [PubMed:15035793 ]
  3. Sun R, Carlson NG, Hemmert AC, Kishore BK: P2Y2 receptor-mediated release of prostaglandin E2 by IMCD is altered in hydrated and dehydrated rats: relevance to AVP-independent regulation of IMCD function. Am J Physiol Renal Physiol. 2005 Sep;289(3):F585-92. Epub 2005 Apr 19. [PubMed:15840771 ]
  4. Celik G, Pasaoglu G, Bavbek S, Abadoglu O, Dursun B, Mungan D, Misirligil Z: Tolerability of selective cyclooxygenase inhibitor, celecoxib, in patients with analgesic intolerance. J Asthma. 2005 Mar;42(2):127-31. [PubMed:15871445 ]
  5. Liu X, Lee TL, Wong PT: Cyclooxygenase-1 inhibition shortens the duration of diazepam-induced loss of righting reflex in mice. Anesth Analg. 2006 Jan;102(1):135-40. [PubMed:16368818 ]
  6. Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. [PubMed:5284360 ]
  7. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Prostaglandin-endoperoxide synthase activity
Specific Function:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, p...
Gene Name:
PTGS2
Uniprot ID:
P35354
Molecular Weight:
68995.625 Da
References
  1. Graham GG, Scott KF: Mechanisms of action of paracetamol and related analgesics. Inflammopharmacology. 2003;11(4):401-13. [PubMed:15035793 ]
  2. Fiebich BL, Chrubasik S: Effects of an ethanolic salix extract on the release of selected inflammatory mediators in vitro. Phytomedicine. 2004 Feb;11(2-3):135-8. [PubMed:15070163 ]
  3. Chae HJ, Chae SW, Reed JC, Kim HR: Salicylate regulates COX-2 expression through ERK and subsequent NF-kappaB activation in osteoblasts. Immunopharmacol Immunotoxicol. 2004 Feb;26(1):75-91. [PubMed:15106733 ]
  4. Wu KK: Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Semin Vasc Med. 2003 May;3(2):107-12. [PubMed:15199473 ]
  5. Elvira C, Gallardo A, Lacroix N, Schacht E, San Roman J: Incorporation of salicylic acid derivatives to hydrophilic copolymer systems with biomedical applications. J Mater Sci Mater Med. 2001 Jun;12(6):535-42. [PubMed:15348270 ]
  6. Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. [PubMed:5284360 ]
  7. Zheng L, Howell SJ, Hatala DA, Huang K, Kern TS: Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. Diabetes. 2007 Feb;56(2):337-45. [PubMed:17259377 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Specific Function:
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Gene Name:
AKR1C1
Uniprot ID:
Q04828
Molecular Weight:
36788.02 Da
References
  1. Dhagat U, Carbone V, Chung RP, Matsunaga T, Endo S, Hara A, El-Kabbani O: A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase. Med Chem. 2007 Nov;3(6):546-50. [PubMed:18045204 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenyto...
Gene Name:
CYP2C9
Uniprot ID:
P11712
Molecular Weight:
55627.365 Da
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]

Carriers

Kind
Protein
Organism
Human
Pharmacological action
no
Actions
other/unknown
General Function:
Toxic substance binding
Specific Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Gene Name:
ALB
Uniprot ID:
P02768
Molecular Weight:
69365.94 Da
References
  1. Bertucci C, Wainer IW: Improved chromatographic performance of a modified human albumin based stationary phase. Chirality. 1997;9(4):335-40. [PubMed:9275312 ]
  2. Xiao HR, Sheng LQ, Shi CH, Xu XL, Xie YS, Liu QL: [Fluorescence study on the interaction of salicylic acid and bovine serum albumin]. Guang Pu Xue Yu Guang Pu Fen Xi. 2004 Jan;24(1):78-81. [PubMed:15768982 ]
  3. Yin T, Wei W, Yang L, Liu K, Gao X: Kinetics parameter estimation for the binding process of salicylic acid to human serum albumin (HSA) with capacitive sensing technique. J Biochem Biophys Methods. 2007 Jun 10;70(4):587-93. Epub 2007 Jan 27. [PubMed:17320187 ]
  4. Yu T, Tao Z: [Fluorescence study on the interaction of salicylic acid and human serum albumin]. Guang Pu Xue Yu Guang Pu Fen Xi. 1999 Jun;19(3):453-5. [PubMed:15819089 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-in...
Gene Name:
SLC22A6
Uniprot ID:
Q4U2R8
Molecular Weight:
61815.78 Da
References
  1. Cihlar T, Ho ES: Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1. Anal Biochem. 2000 Jul 15;283(1):49-55. [PubMed:10929807 ]
  2. Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. [PubMed:12130730 ]
  3. Race JE, Grassl SM, Williams WJ, Holtzman EJ: Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem Biophys Res Commun. 1999 Feb 16;255(2):508-14. [PubMed:10049739 ]
  4. Uwai Y, Saito H, Inui K: Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. Eur J Pharmacol. 2000 Dec 1;409(1):31-6. [PubMed:11099697 ]
  5. Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. [PubMed:10220563 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Not Available
Gene Name:
SLC22A10
Uniprot ID:
Q63ZE4
Molecular Weight:
60256.57 Da
References
  1. Youngblood GL, Sweet DH: Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney. Am J Physiol Renal Physiol. 2004 Aug;287(2):F236-44. Epub 2004 Apr 6. [PubMed:15068970 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
Gene Name:
SLC22A8
Uniprot ID:
Q8TCC7
Molecular Weight:
59855.585 Da
References
  1. Cha SH, Sekine T, Fukushima JI, Kanai Y, Kobayashi Y, Goya T, Endou H: Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol. 2001 May;59(5):1277-86. [PubMed:11306713 ]
  2. Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. [PubMed:12130730 ]
  3. Ohtsuki S, Kikkawa T, Mori S, Hori S, Takanaga H, Otagiri M, Terasaki T: Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier. J Pharmacol Exp Ther. 2004 Jun;309(3):1273-81. Epub 2004 Feb 4. [PubMed:14762099 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.
Gene Name:
SLC22A11
Uniprot ID:
Q9NSA0
Molecular Weight:
59970.945 Da
References
  1. Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H: Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem. 2000 Feb 11;275(6):4507-12. [PubMed:10660625 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.
Gene Name:
SLCO2B1
Uniprot ID:
O94956
Molecular Weight:
76709.98 Da
References
  1. Satoh H, Yamashita F, Tsujimoto M, Murakami H, Koyabu N, Ohtani H, Sawada Y: Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos. 2005 Apr;33(4):518-23. Epub 2005 Jan 7. [PubMed:15640378 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Xenobiotic-transporting atpase activity
Specific Function:
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Gene Name:
ABCB1
Uniprot ID:
P08183
Molecular Weight:
141477.255 Da
References
  1. Faassen F, Vogel G, Spanings H, Vromans H: Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. Int J Pharm. 2003 Sep 16;263(1-2):113-22. [PubMed:12954186 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Symporter activity
Specific Function:
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bod...
Gene Name:
SLC16A1
Uniprot ID:
P53985
Molecular Weight:
53943.685 Da
References
  1. Tamai I, Sai Y, Ono A, Kido Y, Yabuuchi H, Takanaga H, Satoh E, Ogihara T, Amano O, Izeki S, Tsuji A: Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1. J Pharm Pharmacol. 1999 Oct;51(10):1113-21. [PubMed:10579682 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.
Gene Name:
SLC22A7
Uniprot ID:
Q9Y694
Molecular Weight:
60025.025 Da
References
  1. Kobayashi Y, Ohshiro N, Shibusawa A, Sasaki T, Tokuyama S, Sekine T, Endou H, Yamamoto T: Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. Mol Pharmacol. 2002 Jul;62(1):7-14. [PubMed:12065749 ]
  2. Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H: Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett. 1998 Jun 12;429(2):179-82. [PubMed:9650585 ]
  3. Morita N, Kusuhara H, Sekine T, Endou H, Sugiyama Y: Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells. J Pharmacol Exp Ther. 2001 Sep;298(3):1179-84. [PubMed:11504818 ]
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Drug created on June 13, 2005 07:24 / Updated on March 01, 2016 14:10