Refractory absence seizure

Also known as: Refractory absence Seizures

Drug	Drug Name	Drug Description
DB01068	Clonazepam	A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
DB05246	Methsuximide	A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures.

Drug	Drug Name	Target	Type
DB01068	Clonazepam	Cytochrome P450 3A4	enzyme
DB01068	Clonazepam	Serum albumin	carrier
DB01068	Clonazepam	Cytochrome P450 2E1	enzyme
DB01068	Clonazepam	Arylamine N-acetyltransferase 2	enzyme
DB01068	Clonazepam	GABA(A) Receptor	target
DB01068	Clonazepam	Nuclear receptor subfamily 1 group I member 2	target
DB01068	Clonazepam	GABA(A) Receptor Benzodiazepine Binding Site	target
DB05246	Methsuximide	Cytochrome P450 2C19	enzyme
DB05246	Methsuximide	Voltage-dependent T-type calcium channel subunit alpha-1G	target

Drug	Drug Name	Phase	Status	Count