Mitochondrial glutamate carrier 1
Details
- Name
- Mitochondrial glutamate carrier 1
- Synonyms
- GC-1
- GC1
- Glutamate/H(+) symporter 1
- Solute carrier family 25 member 22
- Gene Name
- SLC25A22
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0004468|Mitochondrial glutamate carrier 1 MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSE GYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIV TTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRS RGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAA VAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFG IAQVVYFLGIAESLLGLLQDPQA
- Number of residues
- 323
- Molecular Weight
- 34469.85
- Theoretical pI
- 9.67
- GO Classification
- FunctionsL-glutamate transmembrane transporter activity / symporter activityProcessesL-glutamate transmembrane transport / L-glutamate transportComponentsintegral component of membrane / mitochondrial inner membrane / mitochondrion / nucleoplasm
- General Function
- Symporter activity
- Specific Function
- Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+).
- Pfam Domain Function
- Mito_carr (PF00153)
- Transmembrane Regions
- 12-32 62-82 107-127 189-209 223-243 292-312
- Cellular Location
- Mitochondrion inner membrane
- Gene sequence
>lcl|BSEQ0016737|Mitochondrial glutamate carrier 1 (SLC25A22) ATGGCTGATAAGCAGATCAGCCTGCCAGCCAAGCTCATCAATGGCGGCATCGCCGGGCTG ATCGGTGTCACCTGCGTGTTTCCCATCGACCTGGCCAAGACCAGGCTGCAGAACCAGCAG AACGGCCAGCGCGTGTACACGAGCATGTCCGACTGCCTCATCAAGACCGTCCGCTCCGAG GGCTACTTCGGCATGTACCGGGGAGCTGCTGTGAACTTGACCCTCGTCACCCCCGAGAAG GCCATCAAGCTGGCAGCCAACGACTTCTTCCGACATCAGCTCTCTAAGGACGGGCAGAAG CTGACCCTGCTTAAAGAGATGCTGGCGGGCTGTGGGGCTGGCACCTGCCAGGTGATCGTG ACCACGCCCATGGAGATGCTGAAGATCCAGCTGCAGGATGCAGGGCGCATTGCCGCCCAG AGGAAGATCCTGGCTGCCCAGGGCCAGCTCTCGGCCCAGGGGGGTGCCCAGCCCTCAGTG GAGGCTCCAGCTGCCCCTCGGCCCACGGCCACCCAGCTGACCCGCGACCTGCTGCGGAGC CGTGGCATTGCCGGTCTCTACAAGGGACTCGGGGCCACGCTGCTCAGGGATGTCCCCTTC TCTGTGGTGTACTTCCCGCTCTTTGCCAACCTGAACCAGCTGGGCCGCCCGGCGTCCGAG GAGAAGTCGCCTTTCTACGTGTCCTTCCTGGCCGGCTGTGTGGCTGGGAGTGCCGCCGCT GTGGCCGTCAACCCCTGTGATGTGGTGAAGACGCGGCTCCAGTCACTTCAGCGAGGCGTC AACGAGGACACCTACTCTGGGATCCTGGACTGTGCCAGGAAGATCCTGCGGCACGAGGGC CCCTCGGCCTTCCTGAAGGGCGCCTACTGCCGCGCGCTGGTCATCGCGCCCCTTTTCGGC ATCGCACAGGTGGTCTACTTCCTGGGCATCGCGGAGTCCCTGCTGGGGCTGCTGCAGGAC CCCCAGGCCTGA
- Chromosome Location
- 11
- Locus
- 11p15.5
- External Identifiers
Resource Link UniProtKB ID Q9H936 UniProtKB Entry Name GHC1_HUMAN GenBank Protein ID 21322705 GenBank Gene ID AJ428202 GenAtlas ID SLC25A22 HGNC ID HGNC:19954 - General References
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