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Displaying drugs 26 - 50 of 80 in total
Trabectedin
Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Tetramethylthiuram monosulfide
Approved
Experimental
Matched Synonyms: … Bis(dimethylthiocarbamoyl) sulfide …
Bithionol
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Synonyms: … Bithionol sulfide ... 2-Hydroxy-3,5-dichlorophenyl sulfide ... Bis(3,5-dichloro-2-hydroxyphenyl) sulfide …
Dimercaprol
Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past...
Approved
Matched Description: … It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. …
Indium In-111 oxyquinoline
Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of autologous leukocytes. It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. Indium-111 decays by isomeric transition and electron capture to cadmium-111, emitting a gamma ray that can be detected with a gamma ray...
Approved
Matched Description: … Indium-111 decays by isomeric transition and electron capture to cadmium-111, emitting a gamma ray that …
Sulfinpyrazone
A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Approved
Zofenopril
Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Nizatidine
A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Approved
Nelfinavir
Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Approved
Cadmium
An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
Experimental
Matched Synonyms: … Cadmium metal ... Cadmium metallicum ... Colloidal cadmium …
Matched Name: … Cadmium …
Matched Iupac: … cadmium …
Matched Description: … It is a metal and ingestion will lead to CADMIUM POISONING. …
Matched Name: … Cadmium …
Matched Iupac: … cadmium …
Matched Description: … It is a metal and ingestion will lead to CADMIUM POISONING. …
Rhenium Re-186 sulfide
Experimental
Matched Synonyms: … Rhenium (186Re) sulfide colloid …
Matched Name: … Rhenium Re-186 sulfide …
Matched Categories: … rhenium (186Re) sulfide colloid …
Matched Name: … Rhenium Re-186 sulfide …
Matched Categories: … rhenium (186Re) sulfide colloid …
Calcium sulfide
Experimental
Matched Name: … Calcium sulfide …
Matched Categories: … Hydrogen Sulfide …
Matched Categories: … Hydrogen Sulfide …
Methyl Methylsulfinylmethyl Sulfide
Experimental
Matched Name: … Methyl Methylsulfinylmethyl Sulfide …
(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate
Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …
Ammonium tetrathiomolybdate
Investigational
Matched Synonyms: … Ammonium molybdenum sulfide ((nh4)2mos4) …
Pentasulfide-Sulfur
Experimental
Dioxo(sulfanyl)molybdenum
Experimental
Imrecoxib
Imrecoxib has been used in trials studying the treatment of Knee Osteoarthritis.
Investigational
Matched Categories: … Hydrogen Sulfide …
GW-274150
GW274150 has been used in trials studying the treatment and prevention of Asthma, Migraine, Migraine Disorders, and Arthritis, Rheumatoid.
Investigational
Matched Categories: … Hydrogen Sulfide …
PF-4191834
PF-4191834 has been investigated for the basic science of Asthma.
Investigational
Matched Categories: … Hydrogen Sulfide …
PX-12
PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment...
Investigational
Matched Categories: … Hydrogen Sulfide …
Devimistat
Devimistat (CPI-613) has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others.
Investigational
Matched Categories: … Hydrogen Sulfide …
Displaying drugs 26 - 50 of 80 in total