Displaying drugs 526 - 550 of 606 in total
Calcitonin porcine
Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in...
Experimental
Matched Description: … It inhibits bone resorption and lowers both serum and urinary calcium concentrations. …
Matched Categories: … Calcium Homeostasis …
Matched Categories: … Calcium Homeostasis …
1alpha,24S-Dihydroxyvitamin D2
LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol,...
Investigational
Dotarizine
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Caroverine
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
t-Butylhydroquinone
Experimental
Matched Categories: … Calcium-Transporting ATPases, antagonists & inhibitors …
Doxofylline
Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Description: … Unlike theophylline, doxofylline does not affect calcium influx and does not antagonize the actions of ... calcium channel blockers which could explain reduced cardiac adverse reactions associated with the drug …
Aranidipine
Aranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity. It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate. It was developed by Maruko Seiyaku, introduced by Taiho and launched in Japan in 1997.
Experimental
Matched Description: … It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl …
Matched Categories: … Calcium Channel Blockers …
Matched Categories: … Calcium Channel Blockers …
2,5-di-tert-butylhydroquinone
Experimental
Matched Categories: … Calcium-Transporting ATPases, antagonists & inhibitors …
Tolperisone
Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. Based on existing clinical data, Tolperisone is not...
Investigational
Matched Description: … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. …
Eperisone
Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in the United States, but is available in other countries...
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Terodiline
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Tetrandrine
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Iroxanadine
BRX-235 (iroxanadine) is a a novel small molecule synthesized by Biorex, Hungary that acts as a cardioprotective agent. It induces phosphorylation of p38 SAPK, which plays an important role in EC homeostasis. endothelial cell (EC). EC function plays a central role in vascular diseases (e.g. atherosclerosis, restenosis, diabetic angiopathies, microvascular...
Investigational
Matched Description: … BRX-235 also causes translocation of calcium-dependent protein kinase C isoform to membranes. …
PD-98059
PD-98059 is an inhibitor of MAP-kinase kinase activation.
Investigational
Matched Categories: … Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Naftopidil
Naftopidil has been investigated for the treatment of Disorder of Urinary Stent.
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Salirasib
Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
Investigational
Matched Categories: … Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Morniflumate
Morniflumate is a non-steroidal anti-inflammatory drug with antipyretic properties. It is the morpholinoethyl ester of niflumic acid . In one study, post morniflumate ingestion, physical examination and clinical symptoms of those with bronchitis showed improvement .
Experimental
Sparteine
Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. Sparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one...
Experimental
Withdrawn
Matched Description: … Sparteine is a plant alkaloid derived from _Cytisus scoparius_ and _Lupinus mutabilis_ which may chelate calcium …
Tranilast
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis...
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Otilonium
Experimental
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Formic acid
Formic acid (systematically called methanoic acid) is the simplest carboxylic acid. It is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom of bee and ant stings. It is commonly used as a preservative and antibacterial agent in livestock feed.
Experimental
Investigational
Matched Salts name: … Calcium formate …
Azimilide
Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in the United States.
Investigational
Matched Categories: … Calcium-Regulating Hormones and Agents …
24,25-Dihydroxycholecalciferol
Investigational
Matched Categories: … Calcium-Regulating Hormones and Agents …
Cariporide
Investigational
Agmatine
Agmantine is a natural metabolite of the amino acid arginine. It is formed when arginine is decarboxylated by the enzyme arginine decarboxylase and is found naturally in ragweed pollen, ergot fungi, octopus muscle, herring sperm, sponges, and the mammalian brain. Agmatine is both an experimental and investigational drug. As an...
Experimental
Matched Categories: … Calcium Channel Blockers …
Displaying drugs 526 - 550 of 606 in total