Displaying drugs 126 - 150 of 309 in total
Glycyrrhizic acid
Glycyrrhizic acid is extracted from the root of the licorice plant; Glycyrrhiza glabra. It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin. Glycyrrhizic...
Approved
Experimental
Matched Synonyms: … 18-beta-Glycyrrhizic acid …
Matched Name: … Glycyrrhizic acid …
Matched Iupac: … ]oxy}-5-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3,4-dihydroxyoxane-2-carboxylic acid …
Matched Description: … Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_. ... [F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological ... [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of …
Matched Categories: … glycyrrhizic acid …
Matched Name: … Glycyrrhizic acid …
Matched Iupac: … ]oxy}-5-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3,4-dihydroxyoxane-2-carboxylic acid …
Matched Description: … Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_. ... [F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological ... [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of …
Matched Categories: … glycyrrhizic acid …
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic efficacy and safety, but a much higher hydrophilicity. Normally, hydrophilic bile acids regulates hydrophobic bile acids and...
Approved
Investigational
Matched Synonyms: … Tauroursodesoxycholic acid …
Matched Name: … Tauroursodeoxycholic acid …
Matched Iupac: … -dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid …
Matched Description: … a bile acid derivative. ... Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid ... [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as …
Matched Salts name: … Tauroursodeoxycholic acid dihydrate …
Matched Categories: … Taurodeoxycholic Acid …
Matched Name: … Tauroursodeoxycholic acid …
Matched Iupac: … -dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid …
Matched Description: … a bile acid derivative. ... Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid ... [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as …
Matched Salts name: … Tauroursodeoxycholic acid dihydrate …
Matched Categories: … Taurodeoxycholic Acid …
St. John's Wort
Approved
Investigational
Nutraceutical
Matched Synonyms: … Hypoxis hemerocallidea root extract …
Ocimum tenuiflorum top
Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Holy Basil Leaf/stem …
Plerixafor
Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic stem cell mobilizer.[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune...
Approved
Investigational
Matched Description: … These stem cells are then collected and used in autologous stem cell transplantation to replace blood-forming ... a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic stem ... [A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood …
Matched Categories: … Hematopoietic Stem Cell Mobilizer ... Increased Hematopoietic Stem Cell Mobilization …
Matched Categories: … Hematopoietic Stem Cell Mobilizer ... Increased Hematopoietic Stem Cell Mobilization …
Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Synonyms: … Nicotinic acid amide …
Matched Mixtures name: … Phytofortis + Calcium A-D ... Feminique W Iron and Calcium Tab ... Medi Hydro DP Stem C Ampoule …
Matched Products: … Mari Huana real nature hemp seed ... Stem Cell Whitening Serum ... NYAAM NYAAM Mulberry Stem Serum …
Matched Mixtures name: … Phytofortis + Calcium A-D ... Feminique W Iron and Calcium Tab ... Medi Hydro DP Stem C Ampoule …
Matched Products: … Mari Huana real nature hemp seed ... Stem Cell Whitening Serum ... NYAAM NYAAM Mulberry Stem Serum …
Darvadstrocel
Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted from the subdermal adipose tissue of healthy donors via liposuction. Darvadstrocel was first approved by the European Commission on March 23, 2018, under the brand name Alofisel. It is indicated for the treatment of complex perianal fistulas...
Approved
Experimental
Matched Description: … Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted ... [L39759] It is the first mesenchymal stem cell therapy approved in Europe for this therapeutic indication …
Matched Categories: … Stem Cells …
Matched Categories: … Stem Cells …
Butamben
Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. Due to its very low water solubility, butamben is considered to be suitable only for...
Approved
Withdrawn
Cultivated mushroom
Cultivated mushroom allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Agaricus bisporus (mushroom) cap/stem extract …
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid ... quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid …
Matched Iupac: … chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid …
Matched Iupac: … chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid …
Paclitaxel
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … BENZENEPROPANOIC ACID, .BETA.-(BENZOYLAMINO)-.ALPHA. …
Matched Description: … treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark …
Matched Description: … treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark …
Captopril
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Cinnamaldehyde
Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia.
Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor …
Aluminum sesquichlorohydrate
Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts .
Approved
Matched Products: … Carpe Antiperspirant Underarm Peppermint Bark Scent …
Resorcinol
Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works...
Approved
Matched Categories: … Root Canal Filling Materials …
Crofelemer
Crofelemer, previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark latex of the Amazonian Croton tree Croton lechleri. It is marketed under the brand name Fulyzaq and indicated for the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral...
Approved
Matched Description: … previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark …
Glasdegib
Glasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group of benzimidazoles. In early research, benzimidazoles attracted large interest as they represented a class of inhibitors with low molecular weight, potent inhibitory activity, and lacking unstable functionality. The great lipophilicity of this group of compounds...
Approved
Investigational
Polydatin
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Description: … While it is isolated from the bark of *Picea sitchensis* or *Polygonum cuspidatum*, polydatin may be …
Glycerin
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER ... Essential Solution Hyaluronic Acid Mask Sheet …
Matched Products: … Carrot Seed Oi L Calming Mask 7days ... BRTC Animal Horse ... Origin Horse Sheet Mask …
Matched Products: … Carrot Seed Oi L Calming Mask 7days ... BRTC Animal Horse ... Origin Horse Sheet Mask …
Parachlorophenol
P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible.
Approved
Maribavir
Maribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation. Most standard CMV therapies, such as ganciclovir or foscarnet, target CMV DNA polymerase - while generally effective, these medications tend to promote the development of CMV resistance to DNA...
Approved
Investigational
Formaldehyde
A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor...
Approved
Vet approved
Matched Mixtures name: … Root Canal Therapy …
Elivaldogene autotemcel
Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy, an X-linked genetic disorder characterized by missing or non-functional ABCD1 gene that codes for ALDP. ALDP is a key protein that normally...
Approved
Matched Description: … Allogeneic hematopoietic stem-cell transplantation has been the primary treatment option; however, it ... Gene therapy with autologous hematopoietic stem cells was introduced and investigated as a possible treatment …
Belumosudil
Belumosudil is used in the treatment of chronic graft-versus-host disease (GVHD) and has been investigated for the treatment of pulmonary arterial hypertension. It is an inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK), with significantly more selectivity for ROCK2 as compared to ROCK1 (IC50 100 nM vs. 3 μM, respectively). In...
Approved
Investigational
Matched Description: … condition in which donor T-cells begin to attack recipient tissues following allogeneic hematopoeitic stem …
Vismodegib
Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. Since it targets the hedgehog signaling pathway, vismodegib...
Approved
Investigational
Matched Description: … Afterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells. …
Displaying drugs 126 - 150 of 309 in total