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Identification
NameNicotinamide
Accession NumberDB02701  (EXPT02307)
TypeSmall Molecule
GroupsApproved
Description

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]

Structure
Thumb
Synonyms
Niacinamide
Nicotinic amide
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Niacinamide Ctr Srt 500mgtablet (extended-release)500 mgBioenergy Inc.1981-12-311998-06-03Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Inj 100mg/mlliquid100 mgintramuscular; intravenousKripps Pharmacy Ltd.1979-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Generic Prescription ProductsNot Available
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
A.H.C. C-creamcream1 g/50mLtopicalCarver Korea Co.,Ltd2013-07-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
A.H.C. C-serumcream.6 g/30mLtopicalCarver Korea Co.,Ltd2013-07-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
A.H.C. C-tonerliquid2.4 g/120mLtopicalCarver Korea Co.,Ltd2013-07-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ahc Revitalizing Special Gen Creamcream.6 g/50mLtopicalCarver Korea Co.,Ltd2013-07-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ahc Vital C Complex Maskliquid.6 g/30gtopicalCarver Korea Co.,Ltd2013-08-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ahc Whitening Special Gen Creamcream.6 g/50mLtopicalCarver Korea Co.,Ltd2013-07-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ahc Whitening Special Gen Serumliquid60 mg/30mLtopicalCarver Korea Co.,Ltd2013-07-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ahc Whitening Special Gen Solutionliquid2.4 g/120mLtopicalCarver Korea Co.,Ltd2013-07-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ala-C Snail Cell Reparing Essenceliquid2 g/100mLtopicalDaoomcostech.Co.Ltd.2015-09-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Aqua Collagen Multi Vitamin Hydro Maskpatch.4 g/20gtopicalNature Republic Co., Ltd.2015-02-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Barox White Golfcream3.5 g/50mLtopicalDr.Jang Lab Inc.2015-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Bellaskin Brightening Contour Essencecream2 mL/100mLtopicalAjou Medics Co., Ltd2011-09-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Bha Blackhead Power Liquidliquid2 mg/100mLtopicalCosrx Inc.2015-12-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Bk Cell 5days Of Secret Snow Whiteningpatch.5 mg/25mLtopicalBnk Co., Ltd.2015-06-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Capture C-brightening Ampouleliquid2 g/50mLtopicalCarver Korea Co.,Ltd2013-07-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cell Renew Bioemulsion3 g/150mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cell Renew Bio Tonerliquid3 g/150mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Chaga Anti Wrinkle Eye With Fermented Chaga Extractcream.4 g/20mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Chaga Anti Wrinkle Skin With Fermented Chaga Extractliquid3.2 g/160mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Chaga Anti Wrinkle With Fermented Chaga Extractemulsion2.8 g/140mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dht X Hairlossshampoo1.08 g/360gtopicalIdoogen Co., Ltd.2014-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dht X Scalp Tshampoo1.2 mg/400mLtopicalIdoogen Co., Ltd.2014-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dr Cellinme Mask Sheetpatch.6 mg/51topicalDr.Gene Co.,Ltd2015-06-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dr Cellinme Skin Care Ampoulesolution.1 mg/201topicalDr.Gene Co.,Ltd2015-06-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dr. Color Effect Redcream1 g/50mLtopicalLab & Company Inc.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Gem Miracle Black Pearl O2 Whiteningcream1.2 g/60mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Gem Miracle Black Pearl O2 Whiteningemulsion3 g/150mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Gem Miracle Black Pearl O2 Whitening Snow Serumcream1 g/50mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Gem Miracle Black Pearl O2 Whitening Tonerliquid3 g/150mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ginseng Royal Silkemulsion2.4 mg/120mLtopicalNature Republic Co., Ltd.2015-09-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ginseng Royal Silk Tonerliquid2.4 mg/120mLtopicalNature Republic Co., Ltd.2015-09-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Greentinol Multi Tonersolution2.85 mg/150mLtopicalNature Republic Co., Ltd.2015-10-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
It Radiant Brightening Tonerliquid4 mg/200mLtopicalF&Co Co., Ltd.2015-03-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Manefit Beauty Planner Lily Whitening Brightening Maskcream4.6 mg/23mLtopicalImine Co., Ltd.2014-07-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Manefit Beauty Planner Lily Whitening Eye Patchcream.06 g/3gtopicalImine Co., Ltd.2014-07-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Manefit Bling Bling Whitening Platinum Hydrogel Maskcream.6 g/30gtopicalImine Co., Ltd.2015-09-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Manefit Bling Bling Wrinkle Gold Hydro Gel Maskcream.012 g/30gtopicalImine Co., Ltd.2015-09-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Mineral Homme Whiteemulsion2.6 g/130mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Mineral Homme White Tonerliquid2.6 g/130mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Multi Vita 10 Sleeping Packgel5 mg/100mLtopicalWow Ventures2015-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Neogen Dermalogy Real Fresh Foam Cerealgel.16 g/160gtopicalOutin Futures Corp.2015-07-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Neogen Dermalogy Real Fresh Foam Cranberrygel.16 g/160gtopicalOutin Futures Corp.2015-07-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Neogen Dermalogy Real Fresh Foam Green Teagel.16 g/160gtopicalOutin Futures Corp.2015-07-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Niacinamidecapsule500 mgoralOrganika Health Products Inc.2001-10-012009-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 100 Mg Tabletstablet100 mgoralGeneral Nutrition Canada Inc.1997-04-182005-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 100mgtablet100 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 100mg USP - Tabtablet100 mgoralJamieson Laboratories Ltd1997-09-162001-09-14Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 500 mgcapsule500 mgoralFlora Manufacturing And Distributing Ltd.2002-03-152004-08-04Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 500 Tab 500mgtablet500 mgoralNutri West Products Ltd.1993-12-311997-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 500mgtablet500 mgoralRx Vitamins Inc.1998-09-252007-10-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 500mgtablet500 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 500mgtablet500 mgoralWn Pharmaceuticals Ltd.2002-04-152005-08-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide 500mg - Tabtablet500 mgoralHealth Wise Nutrition Inc.1997-08-151998-08-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 100mgtablet100 mgoralIcn Canada Ltd.1973-12-311998-08-13Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 100mg Yeast Freetablet100 mgoralVita Health Products Inc1972-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 500mgtablet500 mgoralVita Health Products Inc1979-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 500mgtablet500 mgoralQuest Vitamins A Div Of Purity Life Health Products1978-12-312001-07-06Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 500mgtablet500 mgoralHall Laboratories, Ltd.1981-12-312003-09-11Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 500mgtablet500 mgoralNu Life Nutrition Ltd.1987-12-312005-03-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 500mgtablet500 mgoralIcn Canada Ltd.1976-12-311998-08-13Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 500mgtablet500 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1957-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide Tab 500mgtablet500 mgoralKlaire Labs Inc.1984-12-311999-01-18Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niacinamide-S Tab 50mgtablet50 mgoralNutri West Products Ltd.1991-12-311997-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nicotamine Tab 500mgtablet500 mgoralLes Produits Naturels Suisse Inc.1985-12-311996-09-09Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Niveola P.H.c 3d Festival Mask Packcream.54 g/27gtopicalUnisource International Co., Ltd.2015-10-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Niveola White Tiger 3d Animal Mask Packcream.54 g/27gtopicalUnisource International Co., Ltd.2015-10-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Primerose Snail Hydro Essencegel.02 1/120mLtopicalRoyal Springs Cosmetics Usa, Llc2015-06-25Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pure Vita Whitelotion2 g/100gtopicalNature Republic Co., Ltd.2015-08-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pure White Brighteningemulsion2.8 g/140mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pure White Brightening Essencecream1.2 g/60mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Pure White Brightening Tonerliquid3.2 g/160mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Revital Perfecting Dual Ampoulesolution.4 mg/20mLtopicalRaonbio Corp2015-07-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Saccharomyces The Firstcream1 mg/50mLtopicalNature Republic Co., Ltd.2015-08-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Saccharomyces The First Eyecream.5 mg/25mLtopicalNature Republic Co., Ltd.2015-08-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Skederm Ultimate Eyecream.3 mg/15mLtopicalSkederm Inc.2015-11-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Snail Essential EX Wrinkle Essencecream1 g/50mLtopicalThe Saem International Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Snail Gold Hydro Lippatch.2 g/10gtopicalNature Republic Co., Ltd.2015-06-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Stem Cell Whitening Serumliquid.02 mL/mLtopicalMedon Co., Ltd2011-04-06Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Tonymoly Naturalth Goat Milk Whitening Essencecream1 g/50mLtopicalTonymoly Co.,Ltd2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Tonymoly Naturalth Goat Milk Whitening Tonerliquid3 g/150mLtopicalTonymoly Co.,Ltd2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Tonymoly Pandas Dream White Handcream.6 g/30gtopicalTonymoly Co.,Ltd2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ts (talmostop)shampoo.3 mL/100mLtopicalTalmocom Co., Ltd2012-02-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ts (talmostop) Hair Tonicliquid.3 mL/100mLtopicalTalmocom Co., Ltd2012-02-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ts (talmostop) Talhwanpellet.3 g/100gtopicalTalmocom Co., Ltd2012-02-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Ultra Waterfall Creamcream1 mg/50mLtopicalLisz Kei2015-04-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
V V Vitalizing Eyecream.4 mg/20mLtopicalF&Co Co., Ltd.2015-03-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
V V Vitalizing Serumcream.9 mg/45mLtopicalF&Co Co., Ltd.2015-03-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Vita C 35 Tone Up Ampuleliquid.4 mg/20mLtopicalWow Ventures2015-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Vita-acinamid Cap 500mgcapsule500 mgoralLes Laboratoires Vachon Inc.1991-12-311997-02-06Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B3 Tab 500mgtablet500 mgoralShoppers Drug Mart Inc.1980-12-311997-08-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
White Vita Floralemulsion3 g/150mLtopicalNature Republic Co., Ltd.2015-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
White Vita Floral Essence Brighteningcream2 g/40mLtopicalNature Republic Co., Ltd.2015-12-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
White Vita Floral Tonerliquid3 g/150mLtopicalNature Republic Co., Ltd.2015-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
International BrandsNot Available
Brand mixtures
NameLabellerIngredients
Aha 7 Whitehead Power LiquidCosrx Inc.
Ahc Revitalizing Special Gen CreamCarver Korea Co.,Ltd
Ahc Revitalizing Special Gen MaskCarver Korea Co.,Ltd
Ahc Revitalizing Special Gen SerumCarver Korea Co.,Ltd
Ahc Revitalizing Special Gen SolutionCarver Korea Co.,Ltd
Avon Nutrivance Stress FormulaAvon Canada Ulc
B Complex TabletsGolden Neo Life Diamite International, Limited
B Complex W Vit C W Non-med Yeast&liver TabPharmavite Llc
B Complex With C 300mg TabPharmavite Llc
B Plus C 300mg Timed ReleaseVita Health Products Inc
B Stress C + Iron & ViteStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
B With C 500 CapPharmetics (2011) Inc
B-50 Complex TabVita Health Products Inc
B-complex TabletsShaklee Canada Inc
B-plex 100Merit Pharmaceutical
B50 B Complex TabNutristar Health Products (1987) Inc.
B6-niacinamide TabStandard Process Inc.
Balanced B-100 B-complex Vitamins TabPharmavite Llc
Balanced B-100 Timed ReleasePharmavite Llc
Balanced B-complex Vit + Vit C&e TabPharmavite Llc
Beminal 500 TabsWyeth Canada
Beminal With C Fortis PwsWyeth Ayerst Canada Inc.
Bio-fenLisa & Gerry Freundl
BiovitaIldong Pharmaceutical Co., Ltd.
Birds Nest Forever Young Multi Care LiftingF&Co Co., Ltd.
Bonnoir Hair MediCellinbio Co Ltd
C-B ComplexAvacare, Division Of Jeunique International Inc.
Capture Collagen AmpouleCarver Korea Co.,Ltd
Carbassist TabletsWyeth Consumer Healthcare Inc.
Cedevita Plus Vitamin SupplementPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.
Cedevita Sugar-free Vitamin SupplementPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.
Centrum Junior (chewable)Whitehall Robins Inc.
Centrum Junior Regular (chewable Tablets)Whitehall Robins Inc.
Chela Potassium PlusNu Life Nutrition Ltd.
Chewable Children's Complete Multivitamins With Essential MineralsWn Pharmaceuticals Ltd.
Chewable MultivitaminsWn Pharmaceuticals Ltd.
Chewable Multivitamins Plus IronWn Pharmaceuticals Ltd.
Chewable Multivitamins With Extra CWn Pharmaceuticals Ltd.
Children Choice Multivit Chewable TabSwiss Herbal Remedies Ltd.
Children's Chewable Multi-vitaminWn Pharmaceuticals Ltd.
Children's Chewable Multi-vitamin Complete With MineralsWn Pharmaceuticals Ltd.
Children's Chewable Multiple VitaminsStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Children's Chewable Multivitamins With MineralsWn Pharmaceuticals Ltd.
Children's Vitamins ChewableVita Health Products Inc
Childrens Chewable Multiple Vitamins TabPharmavite Llc
Citranatal DHAMission Pharmacal Company
Citranatal RxMission Pharmacal Company
Clapiel Hyalon SerumAus Korea Co., Ltd.
ClerianClerian, Inc.
Clerian Anti-hairlossClerian, Inc.
Clerian HClerian, Inc.
Complex-75Frega Inc.
Complexe B-75Frega Inc.
Daily Energy Brand B-complexEnzymatic Therapy (Canada) Inc.
Denovo 3 HEcomine Co., Ltd.
Dia-viteR & D Laboratories Inc.
DiaplexNephro Tech, Inc.
Doll LashHanbit Korea
Ecosom TonicEcosom.Co.,Ltd.
Ez-flexMetagenics, Inc.
Feminique W Iron and Calcium TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Folcaps Care OneMidlothian Laboratories
For Kids Only Chewable MultivitaminsStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Formula 6100 CapStandard Process Inc.
Formula D.S.Golden Pride International
Galactomyces 95 Whitening Power EssenceCosrx Inc.
Geritol LiquidGlaxosmithkline Consumer Healthcare Inc.
Hasol Anti Hair Loss Day TonicEcomine Co., Ltd.
Hasol Intensive Scalp TonicEcomine Co., Ltd.
Hemarexin AmpLab Bio Chimique Inc.,Division Of Technilab Pharma Inc.
Hemenatal ObWh Nutritionals, Llc
Hesol RimEcomine Co Ltd
Hesol Rim Jean-aeck Hair TonicEcomine Co Ltd
Hesol Rim TonicEcomine Co Ltd
Hormodausse Plus Calc Et D TabLaboratoires Charton Laboratories
Idenel Light R Tox DailySr Biotek Inc.
Idenel Revitalizing EyeSr Biotek Inc.
Junior Multi Vitamins - RegularVita Health Products Inc
Kanga Sport Vitamins B & C Plus MineralsLacombe Drugs (1992) Ltd
Kanga-B Vitamin B Group + CLacombe Drugs (1992) Ltd
Kanga-kid Multi-vitamin & MineralLacombe Drugs (1992) Ltd
Kid's Choice Children's Chewable Vitamins - TabVita Health Products Inc
Kids Stuff TabletsVita Health Products Inc
Kids Stuff With Iron TabletsVita Health Products Inc
Kimchi Vitamin Chewable MultivitaminTobico
Lancell Hair Loss Prevention Hair Grower Clean FormulaMicell Bio Co., Ltd
Lancell Hair Loss Prevention Hair Grower TonicMicell Bio Co., Ltd
Leritone JuniorInstitut De Recherche Biologique Yves Ponroy Canada Inc.
Livron Plus AmpouleMedic Laboratory LtÉe
Maxi 6 LiqDesbergers LtÉe, Division Of Technilab Inc.
Megavites TabIcn Canada Ltd.
Metacinamide TabMetagenics, Inc.
Min-chex CapStandard Process Inc.
Multi #2W 7 Clay Inc.
Multi Vitamin & MineralsWn Pharmaceuticals Ltd.
Multi Vitamin and FluorideLibertas Pharma, Inc.
Multi Vitamin Drops With FluorideSeton Pharmaceuticals
Multi Vitamin Drops With Fluoride and IronSeton Pharmaceuticals
Multi Vitamin Drops With Fluoride With IronStratus Pharmaceuticals
Multi Vitamin Plus IronWn Pharmaceuticals Ltd.
Multi Vitamin, Iron and FluorideLibertas Pharma, Inc.
Multi-vitamin FluorideStratus Pharmaceuticals
Multi-vitaminsWn Pharmaceuticals Ltd.
Multiple VitaminsGfr Pharma Ltd.
Multivit-liqPharmalab Inc.
MultivitaminLaboratoires Confab Inc
Multivitamines Plus C Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamines Plus Fer Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamines Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamins for ChildrenQuest Vitamins A Div Of Purity Life Health Products
MvcSancilio & Company Inc
Mynephrocaps Dialysis/stress Vitamin SupplementMartin Ekwealor Pharmaceuticals, Inc.
Natural Sun AQ Total Anti-aging Essence SunThefaceshop Co., Ltd
Ndm ScalpDamomedical Ltd.
Ndm Scalp TonicDamomedical Ltd.
Neo Bex ElixirNeolab Inc
Neo-bexNeolab Inc
Neo-vites & Minerals TabNeolab Inc
Neogen Agecure One Minute Wrinkle RxOutin Futures Corp.
Neogen Code9 Gold Black Caviar EssenceOutin Futures Corp.
Neogen Code9 Lemon Green Caviar EssenceOutin Futures Corp.
Niaacinamide Azelaic Ac Turmer Fa B6 Zinc Ox CopperVirtus Pharmaceuticals LLC
Niacex B6Therapeutic Foods Co.
Niacin-niacinamide TabSeroyal International Inc.
Niacinamide 250mg With 50mg CGahler Enterprises Ltd.
Niacinamide 250mg With Vitamin CAlbi Naturals
Niacinamide-B6 CapStandard Process Inc.
NicomideAvion Pharmaceuticals, Llc
Nioxin Recharging ComplexNioxin Research Laboratories, Inc.
Nutrol-B-complexRolmex International Inc.
Ouhi Cell Power No 1 EssenceLG Household and Healthcare, Inc.
P1p Chitosan V-maskPhytos Co., Ltd.
P1p Magic Whitening AntiagingPhytos Co., Ltd.
P1p Mela CarePhytos Co., Ltd.
Phosthenine Vitamines Et Fer (ampoules Buvable)Laboratoires Cortunon Inc.
Phs Hair Science Fem Hair Loss TonicRevamp International Pte. Ltd.
Phs Hair Science Hom Hair Loss TonicRevamp International Pte. Ltd.
Phs Hair Science Pro Hair Loss TonicRevamp International Pte. Ltd.
Phytopecia Hair BoostingPhytos Co., Ltd.
Phytopecia Hair TonicPhytos Co., Ltd.
Plalab Placenta Ample EssenceRenocell Co., Ltd
Plalab Placenta MaskRenocell Co., Ltd
Plalab Placenta R-20Renocell Co., Ltd
Plalab Placenta Skin BoosterRenocell Co., Ltd
Pml CronoSifi North America Inc./ Sifi Amerique Du Nord Inc.
Polymine Avec Zinc Et CuivreLes Laboratoires Vachon Inc.
Prefera Ob Plus DHAAlaven Pharmaceutical LLC
PreferaobMEDA Pharmaceuticals
Preferaob Plus DHAAlaven Pharmaceutical LLC
PremelLe Naturiste J.M.B. Inc.
Premium Ts TalmostopTalmocom Co., Ltd
Premium Ts Talmostop RichTalmocom Co., Ltd
Prenate StarAvion Pharmaceuticals, Llc
Prevital TabBio Vita
Primerose EgfRoyal Springs Cosmetics Usa, Llc
Primerose White Milky CbRoyal Springs Cosmetics Usa, Llc
Purevit Dualfe PlusPure Tek Corporation
Reen Hairloss Clinic Jahajin Shampoo for Sensitive ScalpLG Household and Healthcare, Inc.
Rep Nutrinature Ultra All In One MultitemOutin Futures Corp.
Rep Nutrinature Ultra Moist Gel OilOutin Futures Corp.
Rep Nutrinature Ultra Nourishing CreamOutin Futures Corp.
Rep Nutrinature Ultra-all-night Moisture Relief MaskOutin Futures Corp.
ReplaviteStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Ruby Cell 4uDasan E&T Co., Ltd.
Ruby Cell 4u AmpouleDasan E&T Co., Ltd.
Ruby Cell 4u Ampoule PremiumDasan E&T Co., Ltd.
Sallys Box Secret Garden Lemon Oil Ampoule MaskImine Co., Ltd
Se-tan PlusSeton Pharmaceuticals
Sheza Gusl Firming Mask PackPisatap
Simmyungsaengmosu Hair TonicSimmyung Pharmaceutical Co Ltd
Snail Skin BoosterNature Republic Co., Ltd.
Somarexin and C 1000Laboratoire Lalco Inc.
Stress B Complex With C, E & IronPharmavite Llc
Stress Complex 600 Avec Vit E Cuivre ZincFrega Inc.
Stress FormulaVita Health Products Inc
Stress Formula + IronVita Health Products Inc
Stress Formula TabNature's Sunshine Products Of Canada Ltd.
Stress Tab With Iron and Vitamin EVita Health Products Inc
Stress Tab With Zinc, Copper and Vitamin EVita Health Products Inc
Stressease Plus Vitamins and MineralsJamieson Laboratories Ltd
Strovite One CapletsEverett Laboratories, Inc.
Super PantoplexNu Life Nutrition Ltd.
Super Vitalex Ampoule BuvableCarmaran LtÉe
Supravite 10ml AmpouleNobel Pharm Enr.
Supravite Bouteille 250mlNobel Pharm Enr.
Supravite C 1000Nobel Pharm Enr.
Supravite Stress Avec Vit EPharmalab Inc.
Supravite Stress Avec Vit E Cuivre Et ZincPharmalab Inc.
Supravite Stress Avec Vit E Et FerPharmalab Inc.
Swical-energy-2Les Laboratoires Swisse Inc.
T.R.I. B-plex SrcAnabolic Laboratories Inc.
Tandem ObUs Pharmaceutical Corporation
Tandem PlusUs Pharmaceutical Corporation
Tar-endNature's Sunshine Products Inc.
Tender Age Multi VitaminsJamieson Laboratories Ltd
Therapytion Nokmosu Neutral and Oily HairTherapytion Co., Ltd.
Therapytion Nokmosu Sensitive and Dry HairTherapytion Co., Ltd.
Toni Com LiqVitalab
Ultra EnerforceNutribon (1986) Inc.
V-natalVirtus Pharmaceuticals
Vigo Multivitamins Drops/lozengeAshbury Research Corporation
Virt-bal DHA PlusVirtus Pharmaceuticals
Virt-capsVirtus Pharmaceuticals LLC
Virt-PNVirtus Pharmaceuticals
Virt-vite PlusVirtus Pharmaceuticals LLC
Vita-B-75 CapLes Laboratoires Vachon Inc.
Vitabanks Vitamin TabVitabank Inc.
Vitafer - LiqFrega Inc.
Vitamin B ComplexMylan Institutional LLC
Vitamin B Complex Plus C 300mg Timed ReleaseVita Health Products Inc
Vitamine Du Groupe B Plus Fer - LiqPharmalab Inc.
Vitamines Pour Bebes Et EnfantsHerbes Universelles Inc.
Vitogen B Compound W C Fortis CapsulesStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Vitogen B Stress C Vit E Zinc & CopStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Vp-heme ObVirtus Pharmaceuticals LLC
Vp-heme OneVirtus Pharmaceuticals LLC
Vp-zelVirtus Pharmaceuticals
SaltsNot Available
CategoriesNot Available
UNII25X51I8RD4
CAS number98-92-0
WeightAverage: 122.1246
Monoisotopic: 122.048012824
Chemical FormulaC6H6N2O
InChI KeyInChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N
InChI
InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
IUPAC Name
pyridine-3-carboxamide
SMILES
NC(=O)C1=CC=CN=C1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as nicotinamides. These are heterocyclic aromatic compounds containing a pyridine ring substituted at position 3 by a carboxamide group.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassPyridines and derivatives
Sub ClassPyridinecarboxylic acids and derivatives
Direct ParentNicotinamides
Alternative Parents
Substituents
  • Nicotinamide
  • Heteroaromatic compound
  • Primary carboxylic acid amide
  • Carboxamide group
  • Azacycle
  • Carboxylic acid derivative
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Carbonyl group
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External Descriptors
Pharmacology
IndicationNot Available
PharmacodynamicsNot Available
Mechanism of actionNot Available
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityNot Available
Affected organismsNot Available
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9831
Blood Brain Barrier+0.9911
Caco-2 permeable+0.8077
P-glycoprotein substrateNon-substrate0.8778
P-glycoprotein inhibitor INon-inhibitor0.9816
P-glycoprotein inhibitor IINon-inhibitor0.9955
Renal organic cation transporterNon-inhibitor0.8727
CYP450 2C9 substrateNon-substrate0.8702
CYP450 2D6 substrateNon-substrate0.8913
CYP450 3A4 substrateNon-substrate0.7653
CYP450 1A2 substrateNon-inhibitor0.832
CYP450 2C9 inhibitorNon-inhibitor0.9339
CYP450 2D6 inhibitorNon-inhibitor0.9399
CYP450 2C19 inhibitorNon-inhibitor0.9523
CYP450 3A4 inhibitorNon-inhibitor0.9274
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.943
Ames testNon AMES toxic0.9483
CarcinogenicityNon-carcinogens0.9097
BiodegradationNot ready biodegradable0.7807
Rat acute toxicity1.5739 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9947
hERG inhibition (predictor II)Non-inhibitor0.9581
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
PackagersNot Available
Dosage forms
FormRouteStrength
Creamtopical1 g/50mL
Creamtopical.6 g/30mL
Liquidtopical2.4 g/120mL
Creamtopical.6 g/50mL
Liquidtopical.6 g/30g
Liquidtopical60 mg/30mL
Liquidtopical2 g/100mL
Patchtopical.4 g/20g
Tablet (extended-release)oral
Injection, solutionintramuscular; intravenous
Creamtopical3.5 g/50mL
Creamtopical2 mL/100mL
Powder for solutionintravenous
Liquidtopical2 mg/100mL
Granuleoral
Patchtopical.5 mg/25mL
Liquidtopical2 g/50mL
Powderoral
Creamtopical.4 g/20mL
Liquidtopical3.2 g/160mL
Emulsiontopical2.8 g/140mL
Tabletoral
Shampootopical1.08 g/360g
Shampootopical1.2 mg/400mL
Patchtopical.6 mg/51
Solutiontopical.1 mg/201
Creamtopical1.2 g/60mL
Emulsiontopical2.4 mg/120mL
Liquidtopical2.4 mg/120mL
Solutiontopical2.85 mg/150mL
Spraytopical
Geltopical
Liquidtopical4 mg/200mL
Tablet (effervescent)oral
Creamtopical4.6 mg/23mL
Creamtopical.06 g/3g
Creamtopical.6 g/30g
Creamtopical.012 g/30g
Emulsiontopical2.6 g/130mL
Liquidtopical2.6 g/130mL
Geltopical5 mg/100mL
Liquidoral
Solution/ dropsoral
Tablet, chewableoral
Elixiroral
Geltopical.16 g/160g
Tabletoral500 mg
Tablet (extended-release)500 mg
Liquidintramuscular; intravenous100 mg
Tabletoral100 mg
Tabletoral50 mg
Creamtopical.54 g/27g
Patchtopical
Tablet, coatedoral
Shampootopical
Geltopical.02 1/120mL
Lotiontopical2 g/100g
Oiltopical
Solutiontopical.4 mg/20mL
Solutiontopical
Creamtopical1 mg/50mL
Creamtopical.5 mg/25mL
Capsule, gelatin coatedoral
Liquidtopical
Creamtopical.3 mg/15mL
Patchtopical.2 g/10g
Creamtopical
Liquid; tabletoral
Liquidtopical.02 mL/mL
Capsule (sustained-release)oral
Capsuleoral
Shampootopical.3 mL/100mL
Liquidtopical.3 mL/100mL
Pellettopical.3 g/100g
Creamtopical.4 mg/20mL
Creamtopical.9 mg/45mL
Lozengeoral
Kit
Liquidtopical.4 mg/20mL
Capsuleoral500 mg
Tablet
Injectionintravenous
Tablet, film coatedoral
Emulsiontopical3 g/150mL
Creamtopical2 g/40mL
Liquidtopical3 g/150mL
PricesNot Available
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point130 °CPhysProp
boiling point157 °C at 5.00E-04 mm HgPhysProp
water solubility5E+005 mg/L (at 25 °C)MERCK INDEX (1996)
logP-0.37HANSCH,C ET AL. (1995)
logS0.61ADME Research, USCD
pKa3.35 (at 20 °C)PERRIN,DD (1965)
Predicted Properties
PropertyValueSource
Water Solubility50.1 mg/mLALOGPS
logP-0.45ALOGPS
logP-0.39ChemAxon
logS-0.39ALOGPS
pKa (Strongest Acidic)13.39ChemAxon
pKa (Strongest Basic)3.63ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area55.98 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity32.98 m3·mol-1ChemAxon
Polarizability11.71 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (1 TMS)splash10-1z00000000-acb6a21304b0c09c8472View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)splash10-3z00000000-ce86dcff0153b66dd538View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (1 TMS)splash10-zk00000000-790385e574240b8d39deView in MoNA
GC-MSGC-MS Spectrum - GC-MS (2 TMS)splash10-8z60000000-d760b65bb76d6464038eView in MoNA
GC-MSGC-MS Spectrum - GC-MS (1 TMS)splash10-hz00000000-47c6f72d1bb5465c1376View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-8z00000000-72a7c92eb2667f5b6c3fView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-z200000000-6486d230a4a2fd4bab0eView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-z200000000-6486d230a4a2fd4bab0eView in MoNA
LC-MS/MSLC-MS/MS Spectrum - EI-B (HITACHI M-80) , Positivesplash10-zx00000000-89d56b6cb7e033699d24View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positivesplash10-0z00000000-eed71abbb10ba926c13dView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positivesplash10-cz00000000-0c62aa6aba6e23b6c195View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positivesplash10-z500000000-4357a8833611d1756c59View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positivesplash10-z000000000-c9685717817d0081fe6dView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positivesplash10-z000000000-ec0ccca306f38cf72a78View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positivesplash10-hz00000000-f6d71a6c467f84ddd6abView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) 30V, Positivesplash10-z500000000-62c4bd312efbfa37d1a1View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positivesplash10-hz00000000-05714b528dc84942b9dbView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) 30V, Positivesplash10-z600000000-edb6a77c0dfdcbdacc5dView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-1z00000000-2c7ec333d35eb740520aView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-zq00000000-466f98885e2efba73575View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-za00000000-6ef8d7e5edcdd0b02758View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-6z00000000-f38177aa475e58941088View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-zx00000000-6a883d82fcd7c450f6ceView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-z000000000-882d0c59d946a5087b9fView in MoNA
MSMass Spectrum (Electron Ionization)splash10-zp00000000-2b1c5667d92bc1b80b36View in MoNA
1D NMR13C NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
1D NMR13C NMR SpectrumNot Available
2D NMR[1H,1H] 2D NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

Helmut Beschke, Heinz Friedrich, Klaus-Peter Muller, Gerd Schreyer, “Process for the production of nicotinamide.” U.S. Patent US4314064, issued May, 1949.

US4314064
General ReferencesNot Available
External Links
ATC CodesA11HA01
AHFS CodesNot Available
PDB Entries
FDA labelNot Available
MSDSNot Available
Interactions
Drug Interactions
Drug
AtorvastatinThe risk or severity of adverse effects can be increased when Nicotinamide is combined with Atorvastatin.
FluvastatinThe risk or severity of adverse effects can be increased when Nicotinamide is combined with Fluvastatin.
LovastatinThe risk or severity of adverse effects can be increased when Nicotinamide is combined with Lovastatin.
PitavastatinThe risk or severity of adverse effects can be increased when Nicotinamide is combined with Pitavastatin.
PravastatinThe risk or severity of adverse effects can be increased when Nicotinamide is combined with Pravastatin.
RosuvastatinThe risk or severity of adverse effects can be increased when Nicotinamide is combined with Rosuvastatin.
SimvastatinThe risk or severity of adverse effects can be increased when Nicotinamide is combined with Simvastatin.
Food InteractionsNot Available

Targets

1. NAD-dependent protein deacylase sirtuin-5, mitochondrial

Kind: Protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
NAD-dependent protein deacylase sirtuin-5, mitochondrial Q9NXA8 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

2. ADP-ribosyl cyclase 2

Kind: Protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Q10588 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

3. Exotoxin A

Kind: Protein

Organism: Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

Pharmacological action: unknown

Components

Name UniProt ID Details
Exotoxin A P11439 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

4. L-lactate dehydrogenase A chain

Kind: Protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
L-lactate dehydrogenase A chain P00338 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

5. Poly [ADP-ribose] polymerase 1

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: binder

Components

Name UniProt ID Details
Poly [ADP-ribose] polymerase 1 P09874 Details

References:

  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed

Enzymes

1. Cytochrome P450 2D6

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Cytochrome P450 2D6 P10635 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

2. Cytochrome P450 2E1

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Cytochrome P450 2E1 P05181 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

3. Cytochrome P450 3A4

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Cytochrome P450 3A4 P08684 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

Comments
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Drug created on June 13, 2005 07:24 / Updated on October 21, 2015 18:40