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Displaying drugs 226 - 250 of 705 in total

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate ... 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate …
Matched Description: … 40% of its mass accounted for by oxygen. ... In 2004, topiramate was approved for the prevention of migraine in adults. ... Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …

beta-Mannobiose

Experimental
Matched Synonyms: … 4-O-β-D-mannopyranosyl-β-D-mannopyranose …
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy …

beta-D-galactose 6-phosphate

Experimental
Matched Synonyms: … 6-O-phosphono-β-D-galactopyranose …

2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol

Experimental
Matched Synonyms: … 1,4:3,6-Dianhydro-2,5-bis-O-(3-carbamimidoylphenyl)-D-glucitol …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …

Valopicitabine

The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … Exenatide was given FDA approval on April 28, 2005[L6106]. ... It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Fluids and Secretions ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s ... alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and …
Matched Mixtures name: … Cold and Flu All In One ... Care One Cold and Allergy ... Care One Flu and Sore Throat …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Compounds used in a research, industrial, or household setting ... Mydriatics and Cycloplegics ... phenylephrine and ketorolac ... Adrenergic and Dopaminergic Agents …
Matched Products: … OQ-DILAT® ... Care One Nasal Four ... Care One Nose Drops …

Butanilicaine

Experimental
Matched Synonyms: … 2-(Butylamino)-6'-chloro-o-acetoluidide ... 2-Butylamino-6'-chloro-o-acetotoluidide …

Undecylenic acid

Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Description: … of ricinoleic acid, and has been polymerized for vinyl production [A32281]. ... ’s foot and relieves itching, burning, and irritation associated with the skin condition. ... from castor oil. …
Matched Mixtures name: … Desenex Medicated Spray-ON Powder ... Desenex Medicated Spray-ON Powder ... Foot and Body Powder …
Matched Products: … Pinceladas Goyescas Original Brush on Fungicide ... Fungi Nail Toe and Foot ... Fungi Nail Toe and Foot Pen …

Sarocladium strictum

Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …

Fibrinogen human

Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … , including afibrinogenemia and hypofibrinogenemia. ... It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL …

Potassium nitrate

Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Description: … It is a natural source of nitrate and has been used as a constituent for several different purposes, ... or contact [L1754, L1755]. ... In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. …
Matched Mixtures name: … Vet one ... MIPaste ONE ... MIPaste One …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Schmidts WONDERMINT TOOTH AND MOUTH ... SprinJene Natural Sensitivity and Gum ... Strength Sensitive Wintermint clinically proven to reduce painful sensitivity / no artificial dyes or …

Pseudoephedrine

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Iupac: … (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Description: … Eastern medicine and were first researched in the west in 1889. ... Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic ... [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823] …
Matched Mixtures name: … Care One Ibuprofen Cold and Sinus ... Cold and Flu-IN-one Extra Strength ... Cold and Flu-IN-one Regular Strength …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Care One Suphedrine Nasal Decongestant Non Drowsy ... Up and Up Suphedrine ... Up and Up Sinus 12 Hour …

TN-401

TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …

Epigallocatechin gallate

Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Investigational
Matched Synonyms: … (-)-EPIGALLOCATECHIN-3-O-GALLATE ... EPIGALLOCATECHIN 3-O-GALLATE ... 3-O-GALLOYL-(-)-EPIGALLOCATECHIN …
Matched Description: … Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Cefixime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched International brands: … Omnatax-O …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …

Aluminum sesquichlorohydrate

Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts .
Approved
Matched Description: … Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN ... Lactovit DEODORANT ROLL-ON MEN INVISIBLE ... Lactovit Mens Roll On Antiperspirant Deodorant …
Matched Products: … Fraicheur Verveine Antiperspirant and Deodorant Roll-ON ... Fraicheur The Vert Antiperspirant and Deodorant Roll-ON ... Fraicheur Bambou Antiperspirant and Deodorant Roll-ON …

Allantoin

Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products ... The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about …
Matched Mixtures name: … Oil ... Melano Out Mask ... Phenoris Ont …
Matched Categories: … Herbs and Natural Products ... Basic Ointments and Protectants …
Matched Products: … Ohl O2 ... Burn-B Gone OTC ... OLP Scar Cream …

Urofollitropin

Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples. It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51...
Approved
Vet approved
Matched Description: … It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta ... produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or ... The alpha- and beta- subunits have 92 and 111 amino acids. …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BRAVELLE POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 75 IU ... Fostimon 75 IU powder and solvent for solution for injection ... Fostimon 150 IU powder and solvent for solution for injection …

Uridine triacetate

Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Synonyms: … Tri-O-acetyluridine ... 2',3',5'-tri-O-acetyluridine …
Matched Description: … When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites ... Normally, FdUMP inhibits thymidylate synthase required for thymidine synthesis and DNA replication and ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). …
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …

5'-O-(N-Ethyl-Sulfamoyl)Adenosine

Experimental
Matched Name: … 5'-O-(N-Ethyl-Sulfamoyl)Adenosine …

3-O-Methylfructose in Linear Form

Experimental
Matched Name: … 3-O-Methylfructose in Linear Form …
Matched Iupac: … (3S,4R,5R)-1,4,5,6-tetrahydroxy-3-methoxyhexan-2-one …

1,6-DI-O-PHOSPHONO-D-MANNITOL

Experimental
Matched Name: … 1,6-DI-O-PHOSPHONO-D-MANNITOL …
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexyl]oxy}phosphonic acid …

Trisaccharide A

Investigational
Matched Synonyms: … 3-o-(2-acetamido-2-deoxy-.alpha.-d-galactopyranosyl)-2-o-(.alpha.-l-fucopyranosyl)-d-galactose …
Matched Iupac: … 3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}oxan-3-yl]acetamide ... N-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(2R,3S,4S,5R)-4,5,6-trihydroxy-1-oxo-2-{[(2S, …
Displaying drugs 226 - 250 of 705 in total