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Identification
NamePseudoephedrine
Accession NumberDB00852  (APRD00634)
TypeSmall Molecule
GroupsApproved
Description

An alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used in the treatment of several disorders including asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists. [PubChem]

Structure
Thumb
Synonyms
(+)-(1S,2S)-Pseudoephedrine
(+)-Pseudoephedrine
(+)-Psi-ephedrine
(+)-threo-Ephedrine
D-Isoephedrine
D-Pseudoephedrine
D-Psi-2-methylamino-1-phenyl-1-propanol
D-Psi-ephedrine
Isoephedrine
L-(+)-Pseudoephedrine
L(+)-Psi-ephedrine
Pseudoefedrina
Pseudoephedrine
Pseudoephedrinum
Psi-ephedrin
Psi-ephedrine
trans-Ephedrine
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Sudogesttablet, film coated60 mg/1oralbryant ranch prepack1994-10-01Not applicableUs
Approved Generic Prescription ProductsNot Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
12 Hour Decongestanttablet, film coated, extended release120 mg/1oralMeijer Distribution Inc1999-11-05Not applicableUs
12 Hour Decongestanttablet, film coated, extended release120 mg/1oralKroger Company1999-12-14Not applicableUs
12 Hour Decongestanttablet, film coated, extended release120 mg/1oralL Perrigo Company2011-10-04Not applicableUs
12 Hour Nasal Decongestanttablet, film coated, extended release120 mg/1oralCVS Pharmacy1999-12-01Not applicableUs
12 Hour Nasal Decongestant Non Drowsytablet, film coated, extended release120 mg/1oralSafeway2000-05-25Not applicableUs
Balminil Decongestionnant Sirop 30mg/5mlsyrup30 mgoralRougier Pharma Division Of Ratiopharm Inc1988-12-312000-09-07Canada
Benylin D for Infantssyrup7.5 mgoralPfizer Canada Inc., Consumer Healthcare Division2004-08-092006-08-03Canada
Care One Suphedrine Nasal Decongestant Non Drowsytablet, film coated30 mg/1oralAmerican Sales Company2003-12-01Not applicableUs
Careone Suphedrine 12 Hour Relief Non Drowsytablet, film coated, extended release120 mg/1oralAmerican Sales Company2004-05-11Not applicableUs
Childrens Silfedrineliquid15 mg/5mLoralSilarx Pharmaceuticals, Inc2001-01-05Not applicableUs
Childrens Sudafed Nasal Decongestantsolution15 mg/5mLoralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2008-10-01Not applicableUs
Childrens Uniphed Nasal Decongestantliquid15 mg/5mLoralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Congest Aid Tab 30mgtablet30 mgoralZee Medical Inc1990-12-312009-07-30Canada
Congest-eze Tab 60mgtablet60 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1996-10-182002-07-31Canada
Contac Cold Nondrowsy Capsulescapsule (sustained-release)120 mgoralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1997-07-072001-07-31Canada
Contac-C Nondrowsy (sustained Release Cap)capsule (sustained-release)120 mgoralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1994-12-311997-08-15Canada
Cvs Health Non-drowsy Nasal Decongestantpill30 mg/1oralWestport Pharmaceuticals2015-10-05Not applicableUs
Cvs Health Non-drowsy Nasal Decongestantpill30 mg/1oralWestport Pharmaceuticals2015-10-05Not applicableUs
Cvs Health Non-drowsy Nasal Decongestantpill30 mg/1oralWestport Pharmaceuticals2015-10-05Not applicableUs
Decongestant Tabletstablet60 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1996-12-312002-07-31Canada
Eltor 120 Srt 120mgtablet (extended-release)120 mgoralMerrell Dow Pharmaceuticals (Canada) Inc.1992-12-311996-08-29Canada
Ephed 60liquid60 mg/60mLoralDickey Consumer Products DBA DMD2011-10-10Not applicableUs
Equaline 12 Hour Decongestanttablet, film coated, extended release120 mg/1oralSupervalu Inc2004-08-10Not applicableUs
Equaline Nasal Decongestant Non Drowsy Maximum Strengthtablet, film coated30 mg/1oralSupervalu Inc2004-08-17Not applicableUs
Equate Suphedrinetablet, film coated, extended release120 mg/1oralWal Mart Stores Inc2000-07-19Not applicableUs
Good Neighbor Pharmacy Nasal Decongestanttablet, film coated30 mg/1oralAmerisource Bergen1989-08-15Not applicableUs
Good Neighbor Pharmacy Nasal Decongestanttablet, film coated, extended release120 mg/1oralAmerisource Bergen1999-08-12Not applicableUs
Good Sense Nasal Decongestanttablet, film coated30 mg/1oralL Perrigo Company1989-09-15Not applicableUs
Good Sense Suphedrine 12 Hourtablet, film coated, extended release120 mg/1oralL Perrigo Company1999-10-29Not applicableUs
Harris Teeter Sinustablet, film coated30 mg/1oralHarris Teeter, LLC2015-06-23Not applicableUs
Harris Teeter Sinus 12 Hourtablet, film coated, extended release120 mg/1oralHarris Teeter, LLC2015-06-23Not applicableUs
Health Mart Nasal Decongestanttablet, film coated, extended release120 mg/1oralMc Kesson2012-01-11Not applicableUs
Health Mart Nasal Decongestanttablet, film coated30 mg/1oralMc Kesson2011-12-23Not applicableUs
Healthy Accents 12 Hour Nasal Decongestant Maximum Strengthtablet, film coated, extended release120 mg/1oralDZA Brands LLC2011-07-19Not applicableUs
Healthy Accents Nasal Decongestanttablet, film coated30 mg/1oralDZA Brands LLC2011-06-23Not applicableUs
Leader 12 Hour Nasal Decongestanttablet, film coated, extended release120 mg/1oralCardinal Health1999-07-21Not applicableUs
Leader Nasal Decongestant Maximum Strengthtablet, film coated30 mg/1oralCardinal Health1990-06-15Not applicableUs
Maxenal Caplet 120mgtablet120 mgoralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1992-12-312000-07-24Canada
Maxenal Src 240mgcapsule (sustained-release)240 mgoralKv Pharmaceutical Company1992-12-312002-04-29Canada
Members Mark Nasal Decongestant Maximum Strengthtablet, film coated30 mg/1oralSam's West Inc1999-02-03Not applicableUs
Nasal Decongestanttablet, film coated30 mg/1oralCVS Pharmacy1987-07-15Not applicableUs
Nasal Decongestanttablet30 mg/1oralProficient Rx LP2012-10-29Not applicableUs
Nasal Decongestanttablet, film coated30 mg/1oralShopko Stores Operating Co., LLC2013-09-07Not applicableUs
Nasal Decongestanttablet, film coated, extended release120 mg/1oralHy Vee Inc2000-09-11Not applicableUs
Nasal Decongestanttablet, film coated, extended release120 mg/1oralRebel Distributors Corp1999-08-12Not applicableUs
Nasal Decongestanttablet, film coated, extended release120 mg/1oralShopko Stores Operating Co., LLC2014-03-10Not applicableUs
Nasal Decongestanttablet, film coated30 mg/1oralL.N.K. International, Inc.1981-08-25Not applicableUs
Nasal Decongestanttablet, film coated30 mg/1oralPublix Super Markets Inc1993-09-09Not applicableUs
Nasal Decongestanttablet, film coated, extended release120 mg/1oralPublix Super Markets Inc2000-03-20Not applicableUs
Nasal Decongestanttablet, film coated30 mg/1oralL Perrigo Company1987-07-15Not applicableUs
Nasal Decongestanttablet, film coated30 mg/1oralH E B1981-08-25Not applicableUs
Nasal Decongestanttablet, sugar coated30 mg/1oralRUGBY LABORATORIES, INC2011-09-22Not applicableUs
Nasal Decongestanttablet, film coated30 mg/1oralKroger Company1987-07-15Not applicableUs
Nasal Decongestanttablet, sugar coated30 mg/1oralbryant ranch prepack2011-09-22Not applicableUs
Nasal Decongestanttablet30 mg/1oralRugby Laboratories2012-10-29Not applicableUs
Nasal Decongestant Maximum Strengthtablet, film coated30 mg/1oralChain Drug Consortium1981-08-25Not applicableUs
Nasal Decongestant Maximum Strengthtablet30 mg/1oralSUPERVALU INC.1981-08-25Not applicableUs
Nasal Decongestant Maximum Strengthtablet, film coated30 mg/1oralSafeway1981-08-25Not applicableUs
Nasal Decongestant Maximum Strength Non Drowsytablet, film coated30 mg/1oralHannaford Brothers Company1995-07-05Not applicableUs
Nasal Decongestant Maximum Strength Non Drowsytablet, film coated30 mg/1oralSafeway1987-07-15Not applicableUs
Nasal Decongestant Maximum Strength Non Drowsytablet, film coated30 mg/1oralMeijer Distribution Inc1991-02-15Not applicableUs
Nasal Decongestant Non Drowsytablet, film coated30 mg/1oralHy Vee Inc1989-01-15Not applicableUs
Nasal Decongestant Non-drowsytablet, film coated30 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1981-08-25Not applicableUs
Nexafedtablet30 mg/1oralAcura Pharmaceuticals, Inc.2012-12-10Not applicableUs
Non Drowsy Regular Strength Contac Cold 12 Hourtablet (extended-release)120 mgoralGlaxosmithkline Consumer Healthcare Inc.1999-08-162009-07-28Canada
Plus Sinustablet (extended-release)120 mgoralPfizer Canada Inc., Consumer Healthcare Division1999-02-112000-08-03Canada
Preferred Plus Sinustablet, film coated30 mg/1oralKinray2014-06-09Not applicableUs
Pseudo-timetablet, coated30 mg/1oralTIME CAP LABORATORIES, INC.2012-05-01Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralCVS Pharmacy2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated60 mg/1oralPhysicians Total Care, Inc.2002-11-25Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralWalgreen Company2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, extended release120 mg/1oralOhm Laboratories Inc.2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralChain Drug Consortium, LLC2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralShopko Stores Operating Co., LLC2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated120 mg/1oralOhm Laboratories Inc.2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, coated30 mg/1oralAAA Pharmaceutical, Inc.2012-12-22Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralPublix Super Markets Inc2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralHEB2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralAmerisource Bergen2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralChain Drug Marketing Association Inc.2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralREMEDYREPACK INC.2015-10-27Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated30 mg/1oralPerrigo New York Inc2008-10-17Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralSafeway Inc.2006-04-28Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralPerrigo New York Inc2014-05-24Not applicableUs
Pseudoephedrine Hydrochloridetablet, film coated, extended release120 mg/1oralMeijer Distribution, Inc.2006-04-28Not applicableUs
Pseudoephedrine Hydrochloride Srt 120mg Tabtablet (extended-release)120 mgoralKv Pharmaceutical Company1990-05-042002-04-29Canada
Pseudoephedrine Non Drowsy Formulatablet30 mg/1oralContract Pharmacal Corp2001-06-21Not applicableUs
Pseudoephedrine Non-drowsy Formulatablet60 mg/1oralContract Pharmacal Corp2001-07-17Not applicableUs
Pulmosirum 5 Tab 60mgtablet60 mgoralNutribon (1986) Inc.1992-12-311996-09-30Canada
Robidrine Tab 60mgtablet60 mgoralWhitehall Robins Inc.1993-12-312000-07-26Canada
Rugby Nasal Decongestantliquid30 mg/5mLoralRugby Laboratories, Inc.1999-07-26Not applicableUs
Rugby Nasal Decongestantliquid30 mg/5mLoralbryant ranch prepack1999-07-26Not applicableUs
Rugby Nasal Decongestant Nasal Decongestantliquid30 mg/5mLoralDispensing Solutions, Inc.1999-07-26Not applicableUs
Rx Act Nasal Decongestanttablet, film coated30 mg/1oralH E B2006-02-13Not applicableUs
Shoprite Nasal Decongestanttablet, film coated30 mg/1oralWakefern Food Corporation2013-09-17Not applicableUs
Shoprite Nasal Decongestanttablet, film coated, extended release120 mg/1oralWakefern Food Corporation2014-03-25Not applicableUs
Sinus Pressure and Congestion Relief Maximum Strengthtablet, film coated, extended release120 mg/1oralRite Aid Corporation1999-08-30Not applicableUs
Sinus Pressure and Congestion Relief Maximum Strengthtablet30 mg/1oralRite Aid1981-08-25Not applicableUs
Smart Sense 12 Hour Decongestanttablet, film coated, extended release120 mg/1oralKmart Corporation2011-03-14Not applicableUs
Smart Sense Nasal Decongestanttablet, film coated30 mg/1oralKmart Corporation2011-03-14Not applicableUs
Smart Sense Nasal Decongestanttablet, film coated, extended release120 mg/1oralKmart Corporation2014-02-18Not applicableUs
Smart Sense Sinustablet, film coated30 mg/1oralKmart Corporation2015-08-27Not applicableUs
Smart Sense Sinus 12 Hourtablet, film coated, extended release120 mg/1oralKmart Corporation2015-08-17Not applicableUs
Sudafedtablet, coated30 mg/1oralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2011-10-01Not applicableUs
Sudafed 12 Hourtablet, film coated, extended release120 mg/1oralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2008-06-01Not applicableUs
Sudafed 24 Hourtablet, extended release240 mg/1oralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2008-10-01Not applicableUs
Sudafed Decongestant 12 Hour Caplets - 120mgtablet120 mgoralWarner Lambert Canada Inc.1996-10-111999-08-13Canada
Sudafed Decongestant Children's Chewable Tabletstablet15 mgoralPfizer Canada Inc., Consumer Healthcare Division1998-08-132006-08-03Canada
Sudafed Decongestant Extra Strength Tablettablet60 mgoralPfizer Canada Inc., Consumer Healthcare Division1998-11-302006-08-03Canada
Sudafed Decongestant Extra Strength Tabletstablet60 mgoralWarner Lambert Canada Inc.1996-10-111999-08-13Canada
Sudafed Decongestant Regular Strength Syrupsyrup30 mgoralWarner Lambert Canada Inc.1998-11-302000-08-01Canada
Sudafed Decongestant Regular Strength Syrupsyrup30 mgoralWarner Lambert Canada Inc.1996-10-111999-08-13Canada
Sudafed Decongestant Regular Strength Tablettablet30 mgoralWarner Lambert Canada Inc.1996-10-111999-08-13Canada
Sudafed Decongestant Regular Strength Tablettablet30 mgoralWarner Lambert Canada Inc.1998-11-302000-08-01Canada
Sudafed Nasal Cold 12 Hour Capletstablet120 mgoralGlaxo Wellcome Inc.1995-12-312000-08-03Canada
Sudafed Nasal Cold Extra Strength Tabletstablet60 mgoralGlaxo Wellcome Inc.1995-12-312000-08-03Canada
Sudafed Nasal Cold Regular Strength Syrupsyrup30 mgoralGlaxo Wellcome Inc.1995-12-312000-08-03Canada
Sudafed Nasal Cold Regular Strength Tabstablet30 mgoralGlaxo Wellcome Inc.1995-12-312000-08-03Canada
Sudafed Syr 30mg/5mlsyrup30 mgoralBurroughs Wellcome Inc.1958-12-312000-08-02Canada
Sudafed Tab 60mgtablet60 mgoralBurroughs Wellcome Inc.1958-12-312000-08-02Canada
Sudodrin Tab 60mgtablet60 mgoralIcn Canada Ltd.1979-12-311998-08-13Canada
Sudogesttablet30 mg/1oralA S Medication Solutions Llc1981-08-25Not applicableUs
Sudogesttablet, film coated60 mg/1oralH.J. Harkins Company, Inc.1994-10-01Not applicableUs
Sudogesttablet, film coated60 mg/1oralProficient Rx LP1994-10-01Not applicableUs
Sudogesttablet, coated30 mg/1oralMajor Pharmaceuticals2014-02-17Not applicableUs
Sudogesttablet, film coated60 mg/1oralREMEDYREPACK INC.2015-08-04Not applicableUs
Sudogesttablet30 mg/1oralA S Medication Solutions Llc1981-08-25Not applicableUs
Sudogesttablet30 mg/1oralREMEDYREPACK INC.2015-06-02Not applicableUs
Sudogesttablet, film coated60 mg/1oralA S Medication Solutions Llc1994-10-01Not applicableUs
Sudogesttablet, film coated60 mg/1oralA S Medication Solutions Llc1994-10-01Not applicableUs
Sudogesttablet60 mg/1oralDispensing Solutions, Inc.1994-10-01Not applicableUs
Sudogesttablet, film coated, extended release120 mg/1oralMajor Pharmaceuticals2006-04-28Not applicableUs
Sudogesttablet, film coated30 mg/1oralA S Medication Solutions1981-08-25Not applicableUs
Sudogestliquid15 mg/5mLoralMajor Pharmaceuticals, Inc2001-01-05Not applicableUs
Sudogesttablet, film coated60 mg/1oralRebel Distributors Corp1994-10-01Not applicableUs
Sudogesttablet, film coated, extended release120 mg/1oralREMEDYREPACK INC.2015-12-17Not applicableUs
Sudogesttablet, film coated60 mg/1oralMajor Pharmaceuticals1994-10-01Not applicableUs
Sudogesttablet30 mg/1oralRebel Distributors Corp1994-10-01Not applicableUs
Sudogesttablet, film coated30 mg/1oralMajor Pharmaceuticals1981-08-25Not applicableUs
Sudogesttablet, film coated60 mg/1oralAidarex Pharmaceuticals LLC1994-10-01Not applicableUs
Sudogesttablet, film coated60 mg/1oralUnit Dose Services1994-10-01Not applicableUs
Sudogest Nasal Decongestanttablet, film coated30 mg/1oralMajor Pharmaceuticals1991-09-10Not applicableUs
Sunmark Nasal Decongestanttablet, film coated30 mg/1oralMc Kesson2003-08-15Not applicableUs
Sunmark Sinus 12 Hourtablet, film coated, extended release120 mg/1oralMc Kesson2003-06-24Not applicableUs
Suphedrinetablet, film coated, extended release120 mg/1oralRite Aid Corporation2002-08-13Not applicableUs
Suphedrinetablet, film coated30 mg/1oralWal Mart Stores Inc1981-08-25Not applicableUs
Suphedrine Maximum Strengthtablet, film coated30 mg/1oralChain Drug Marketing Association Inc1981-08-25Not applicableUs
Topcare 12 Hour Decongestanttablet, film coated, extended release120 mg/1oralTopco Associates LLC2000-04-25Not applicableUs
Topcare Nasal Decongestant Maximum Strength Non Drowsytablet, film coated30 mg/1oralTopco Associates LLC1988-01-15Not applicableUs
Triaminic Allergy Congestionliquid30 mgoralNovartis Consumer Health Canada Inc.2001-07-162006-07-04Canada
Triaminic Pediatric Oral Cold Drops - 7.5mg/0.8mlliquid7.5 mgoralNovartis Consumer Health Canada Inc.1995-12-312008-07-15Canada
Up and Up 12 Hour Nasal Decongestanttablet, film coated, extended release120 mg/1oralTarget Corporation2009-09-02Not applicableUs
Up and Up Nasal Decongestanttablet, film coated30 mg/1oralTarget Corporation2009-08-04Not applicableUs
Up and Up Sinus 12 Hourtablet, film coated, extended release120 mg/1oralTarget Corporation2015-03-13Not applicableUs
Up and Up Suphedrinetablet, film coated30 mg/1oralTarget Corporation2015-03-13Not applicableUs
Wal Phedtablet, film coated, extended release120 mg/1oralWalgreen Company1999-09-24Not applicableUs
Wal-phedtablet, film coated30 mg/1oralWALGREEN CO.1981-08-25Not applicableUs
Walphed D Maximum Strength Non Drowsy Sinustablet, film coated, extended release120 mg/1oralWalgreen Company1999-09-24Not applicableUs
Zephrex-Dtablet30 mg/1oralWestport Pharmaceuticals2012-11-15Not applicableUs
Unapproved/Other Products Not Available
International Brands
NameCompany
AfrinolNot Available
Benylin DecongestantNot Available
CenafedNot Available
DecofedNot Available
Dimetapp DecongestantNot Available
Eltor 120Not Available
GenaphedNot Available
MaxenalNot Available
MyfedrineNot Available
NovafedNot Available
RobidrineNot Available
Sudafed DecongestantNot Available
Brand mixtures
NameLabellerIngredients
12 Hour Allergy DMeijer Distribution Inc
A.M. Cold Relief FormulaIvax Pharmaceuticals Incorporated
Abanatuss PedKramer Novis
Abanatuss Ped DropsKramer Novis
Abatuss DmxKramer Novis
Acetaminophen/dextromethorphan/pseudoephedrineApotex Inc
Acetaminophen/pseudoephedrine/dextromethorphan/doxylamineApotex Inc
ActiconActipharma, Inc
Actifed DM SyrupGlaxo Wellcome Inc.
Actifed DM TabletsGlaxo Wellcome Inc.
Actifed Plus CapletGlaxo Wellcome Inc.
Actifed Plus CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Actifed SyrupGlaxo Wellcome Inc.
Actifed TabletsGlaxo Wellcome Inc.
ActinelActipharma, Inc
Actinel PediatricActipharma, Inc
Advil Allergy SinusPfizer Consumer Healthcare
Advil Cold & Sinus Convenience PackPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Advil Cold & Sinus Liqui-gelsPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Advil Cold and SinusPfizer Consumer Healthcare
Advil Cold and Sinus DaytimePfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Advil Cold and Sinus NighttimePfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Advil Cold and Sinus PlusPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Aerius Dual Action 12 HourBayer Inc Consumer Care
Aerius Dual Action 24 HourBayer Inc Consumer Care
Alavert Allergy Sinus D-12Wyeth Consumer Healthcare
Alka-seltzer Plus-D Multi-symptom Sinus and ColdBayer Health Care Llc, Consumer Care
All Day Allergy DMajor Pharmaceuticals
All Day Allergy Relief DH E B
All Day Allergy-DL. Perrigo Company
All Day Sinus and Cold DWalgreen Company
Allegra D 12 Hour Allergy and CongestionRebel Distributors Corp
Allegra D-12 HourSanofi Aventis U.S. Llc
Allegra--d 24 HourSanofi Aventis U.S. Llc
Allegra-Dbryant ranch prepack
Allegra-D 24 HourSTAT Rx USA LLC
Allegra-D Allergy and CongestionChattem, Inc.
Allerclear-D 24 HourCostco Wholesale Corporation
Allergy + Sinus Relief Extra Strength TabletsPharmetics (2011) Inc
Allergy + Sinus Relief Regular CapletsPharmetics (2011) Inc
Allergy and Congestion ReliefL. Perrigo Company
Allergy and Congestion Relief D Original Prescription StrengthRite Aid Corporation
Allergy and Congestion Relief Non DrowsyAmerisource Bergen
Allergy Relief DShopko Stores Operating Co., LLC
Allergy Relief D 12CVS Pharmacy
Allergy Relief D 12 HourPublix Super Markets Inc
Allergy Relief D 24 HourPublix Super Markets Inc
Allergy Relief-DCVS Pharmacy
Allergy Relief-D 24 HourShopko Stores Operating Co., LLC
Allergy Relief-d24 Hour 24 HourTopco Associates LLC
Allergy Sinus Headache CapletsTanta Pharmaceuticals Inc
Allergy Sinus Medication - CapletWestcan Pharmaceuticals Ltd.
Allergy Sinus Nighttime ReliefVita Health Products Inc
Allergy, Sinus and Headache Relief MedicationPharmetics (2011) Inc
Allpanto SSAMSUNG PHARM IND. CO., LTD.
AprodineRebel Distributors Corp
Atuss DaAber Pharmaceuticals, Llc
Atuss DS Tannate SuspensionAtley Pharmaceuticals, Inc.
Balminil Codeine + Decongestant + ExpectorantRougier Pharma Division Of Ratiopharm Inc
Balminil Cough and FluRougier Pharma Division Of Ratiopharm Inc
Balminil DM + DecongestantRougier Pharma Division Of Ratiopharm Inc
Balminil DM + Decongestant + ExpectorantTeva Canada Limited
Balminil DM + Decongestant + Expectorant Extra StrengthTeva Canada Limited
Balminil DM-D-E - LiqRougier Pharma Division Of Ratiopharm Inc
Benadryl Allergy & Cold CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benadryl Allergy Sinus CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benadryl Decongestant TabletsWarner Lambert Canada Inc.
Benadryl TotalMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin 2 Cold and Flu With CodeineMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin 4 Flu - SyrupPfizer Canada Inc., Consumer Healthcare Division
Benylin A-D Extra Strength CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin A-D Regular Strength CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin A-D-AH Extra Strength CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin A-D-AH Regular Strength CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin All-IN-one Cold and Flu Extra StrengthMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin All-IN-one Cold and Flu Extra Strength SyrupMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin All-IN-one Cold and Flu Liquid GelsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin All-IN-one Cold and Flu Night Extra StrengthMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin All-IN-one Cold and Flu Night Extra Strength SyrupMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin Codeine 3.3mg De SyrPfizer Canada Inc., Consumer Healthcare Division
Benylin Cough and Chest Congestion Extra Strength With Warming SensationMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin Cough and ColdMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin Cough Plus Cold ReliefMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin D-AH for ChildrenMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin DM-DMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin DM-D Chewables for ChildrenMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin DM-D for ChildrenMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin DM-D for InfantsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin DM-D-AH Chewables for ChildrenMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin DM-D-AH for ChildrenMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin DM-D-E-A Cold and Sinus Liquid GelsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin Extra Strength All-IN-one Cold and Flu With Warming SensationMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin Extra Strength Cough Plus Cold ReliefMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin Extra Strength Mucus & Phlegm Plus Cold ReliefMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin Extra Strength Mucus & Phlegm Plus Cold Relief NightMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin for Children All-IN-one Cold & FeverMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin for Children All-IN-one Cold and FeverMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Benylin for Children Cough Stuffy and Runny NoseMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Bio Dtuss DmxAdvanced Generic Corporation
BionelAdvanced Generic Corporation
Bionel PediatricAdvanced Generic Corporation
Bromfed DMClinical Solutions Wholesale
Bromfeddm DMPhysicians Total Care, Inc.
Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan HydrobromidePaddock Laboratories, LLC
Brompheniramine Maleate, Pseudoephedrine Hydrochloride and DextromethorphanhydrobromideMorton Grove Pharmaceuticals, Inc.
Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan HydrobromideBoca Pharmacal, LLC
Bronchodex PediatriqueTherapex Division De E Z Em Canada Inc
BrotappSilarx Pharmaceuticals, Inc
Brotapp DM Cold and CoughSilarx Pharmaceuticals, Inc
Brovex PsbMcr American Pharmaceuticals, Inc.
Brovex Psb DMMcr American Pharmaceuticals, Inc.
Buckley's Cold & Sinus DayThe Buckley's Company
Buckley's Cold & Sinus NightThe Buckley's Company
Buckley's Complete Daytime Plus Mucus Relief SoftgelsThe Buckley's Company
Buckley's Complete Daytime SoftgelsThe Buckley's Company
Buckley's Complete Extra Strength Cough, Cold & Flu DayThe Buckley's Company
Buckley's Complete Extra Strength Cough, Cold and Flu NightThe Buckley's Company
Buckley's Complete Nighttime SoftgelsThe Buckley's Company
Buckley's DM DecongestantThe Buckley's Company
Buckley's Sinus Pain Relief Extra Strength TabletsThe Buckley's Company
Buckleys Daytime Cold and SinusThe Buckley's Company
Buckleys Nighttime Cold and SinusThe Buckley's Company
Calmylin #2 SyrTechnilab Pharma Inc.
Calmylin #3 SyrTechnilab Pharma Inc.
Calmylin Codeine D-E SyrTechnilab Pharma Inc.
Calmylin Cough and Flu LiqTechnilab Pharma Inc.
Calmylin Pediatric SyrupTechnilab Pharma Inc.
Calmylin Pse With CodeineTeva Canada Limited
Capmist DMCapital Pharmaceutical, Llc
Care One Ibuprofen Cold and SinusAmerican Sales Company
Careone All Day Allergy DAmerican Sales Company
Careone Allergy and Congestion ReliefAmerican Sales Company
Centracol Pediatrique - SyrPrometic Pharma Inc.
Cetiri DRite Aid Corporation
Cetirizine HCl and Pseudoephedrine HCl ERPhysicians Total Care, Inc.
Cetirizine Hydrochloride and Pseudoephedrine HydrochloridePerrigo New York Inc
Cheratussin DacQualitest Pharmaceuticals
Children's Advil ColdPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Children's Advil Cold & Flu Multi-symptomPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Children's Allergy and Sinus Medication Liquid SuspensionPharmetics (2011) Inc
Children's Benadryl-D Allergy & SinusMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Cough & Cold ReliefTrillium Health Care Products Inc
Children's Motrin ColdMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Nicold MedicineTanta Pharmaceuticals Inc
Children's Nyquil LiquidProcter & Gamble Inc
Children's Sinus Medication Liquid SuspensionPharmetics (2011) Inc
Children's Tussin Cough Medicine DM Antitussive DecongestantStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Children's Tylenol Allergy - D Chewable TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Allergy-D SuspensionMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Cold & Stuffy NoseMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Cold and CoughMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Cold Chewable TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Cold LiquidMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Cold Liquid With DMMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Cold SuspensionMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Complete Cold, Cough & FeverMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Decongestant - TabMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Sinus Chewable TabletMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Children's Tylenol Sinus SuspensionMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Childrens Advil ColdPfizer Consumer Healthcare
Chlo TussR.A. Mc Neil Company
Chlor-tripolon Decon Ext Str Repetabs 12Schering Plough Canada Inc
Chlor-tripolon Nd SrtSchering Plough Canada Inc
Clarinex-D 12 HourMerck Sharp & Dohme Corp.
Claritin Allergy + SinusBayer Inc Consumer Care
Claritin Allergy + Sinus Extra StrengthBayer Inc Consumer Care
Claritin-D 12 HourMSD Consumer Care, Inc.
Claritin-D 24 HourMSD Consumer Care, Inc.
CloferaCentrix Pharmaceutical, Inc.
CoactifedGlaxosmithkline Inc
Codar DRespa Pharmaceuticals
Cold & CoughPharma Strides Canada Corporation
Cold & Cough Extra StrengthPharma Strides Canada Corporation
Cold & FluPharma Strides Canada Corporation
Cold & Flu DaytimeArrow Otc Company
Cold & Flu NighttimeArrow Otc Company
Cold & Flu-IN-oneVita Health Products Inc
Cold & Sinus Liquid CapsulesVita Health Products Inc
Cold & Sinus Liquid FastgelsVita Health Products Inc
Cold & Sinus Relief CapsulesApotex Inc
Cold + SinusVita Health Products Inc
Cold + Sinus CapletsVita Health Products Inc
Cold + Sinus DaytimeVita Health Products Inc
Cold + Sinus Daytime Cold + Sinus NighttimeVita Health Products Inc
Cold + Sinus NighttimeVita Health Products Inc
Cold + Sinus PlusVita Health Products Inc
Cold and Cough Relief Extra StrengthPharmetics (2011) Inc
Cold and Flu CapsulesVita Health Products Inc
Cold and Flu Extra Strength DayPharmetics (2011) Inc
Cold and Flu Medicine - Day Time FormulaPharmetics (2011) Inc
Cold and Flu Medicine - Night Time FormulaPharmetics (2011) Inc
Cold and Flu Nighttime DWalgreen Company
Cold and Flu Nighttime Relief Syrup Extra StrengthPharmetics (2011) Inc
Cold and Flu-IN-one Extra StrengthVita Health Products Inc
Cold and Flu-IN-one Regular StrengthVita Health Products Inc
Cold and Nasal Congestion Relief Nighttime Extra StrengthPharmetics (2011) Inc
Cold and Nasal Congestion Relief Super StrengthPharmetics (2011) Inc
Cold and Sinus Complete Liquid GelsVita Health Products Inc
Cold and Sinus Daytime ReliefVita Health Products Inc
Cold and Sinus Nighttime ReliefVita Health Products Inc
Cold and Sinus Pain ReliefSafeway
Cold and Sinus PlusInternational Pharmaceutical Generics Ltd
Cold and Sinus ReliefCVS Pharmacy
Cold and Sinus Relief ComboVita Health Products Inc
Cold Flu ReliefPerrigo International
Cold MedicationVita Health Products Inc
Cold Medication Extra Strength DaytimePharmascience Inc
Cold Medication Extra Strength Night TimePharmascience Inc
Cold Medication Reg Strength D TabProdemdis Enr.
Cold Medication Reg Strength N TabProdemdis Enr.
Cold Medication Regular Nighttime TabletsPharmetics (2011) Inc
Cold Relief Daytime TabletJamp Pharma Corporation
Cold Relief Duo PackPharmetics (2011) Inc
Cold Relief Nightime TabletJamp Pharma Corporation
Cold,sore Throat Pain & Cough Ultra StrengthThe Winning Combination Inc.
Cold/flu ReliefPerrigo International
CompleteVita Health Products Inc
Complete DaytimeVita Health Products Inc
Complete Daytime Liquid CapsulesVita Health Products Inc
Complete Liquid CapsulesVita Health Products Inc
Complete Liquid Capsules Nighttime ReliefVita Health Products Inc
Complete One Cold and Flu Extra StrengthTanta Pharmaceuticals Inc
Complete One Cold and Flu Extra Strength TabletsTanta Pharmaceuticals Inc
Complete One Cold and Flu Nightime Extra Strength LiquidTanta Pharmaceuticals Inc
Complete One Cold and Flu Nightime Extra Strength TabletsTanta Pharmaceuticals Inc
ConexLlorens Pharmaceuticals International Division
CongestacBF ASCHER AND CO INC
Contac Cold and Fever CapletsGlaxosmithkline Consumer Healthcare Inc.
Contac Cold and Sore Throat CapletsGlaxosmithkline Consumer Healthcare Inc.
Contac Cold Nasal Congestion-nighttimeGlaxosmithkline Consumer Healthcare Inc.
Contac Cold Nasal Congestion-non Drowsy Regular StrengthGlaxosmithkline Consumer Healthcare Inc.
Contac Complete Cough, Cold & Flu SyrupGlaxosmithkline Consumer Healthcare Inc.
Contac Cough & Cold SyrupGlaxosmithkline Consumer Healthcare Inc.
Contac Day & Night Sinus/allergy CapletSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.
Contac Extend-C Sustained Release CapsulesGlaxosmithkline Consumer Healthcare Inc.
Contac Night CapletsGlaxosmithkline Consumer Healthcare Inc.
Contac-C Ext.stren.night Time Cough,cold&fluSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.
CopantoSAMSUNG PHARM IND. CO., LTD.
Coricidin 'd' Nasal and Sinus CongestionSchering Plough Healthcare Products Canada, A Division Of Schering Canada Inc.
Coricidin D Flu, Nasal and SinusSchering Plough Healthcare Products Canada, A Division Of Schering Canada Inc.
Coricidin D Nasal and Sinus Congestion TabletsSchering Plough Healthcare Products Canada, A Division Of Schering Canada Inc.
CotrifedTechnilab Pharma Inc.
Cough & ColdPharmetics (2011) Inc
Cough & Cold ReliefTrillium Health Care Products Inc
Cough & Cold Relief Extra StrengthTrillium Health Care Products Inc
Cough & Cold Soft Gel CapsApotex Inc., Private Label Division
Cough and Flu SyrupTechnilab Pharma Inc.
Cough Plus Cold Relief SyrupPharmetics (2011) Inc
Cough Syr W.cod. Pseudoephed.hcl GuaifenesinStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Cough Syrup DM - Decongestant - ExpectorantJamp Pharma Corporation
Cough Syrup DM - Decongestant - Expectorant Extra StrengthJamp Pharma Corporation
Cough Syrup DM - Decongestant for ChildrenJamp Pharma Corporation
Cough Syrup DM DecongestantJamp Pharma Corporation
Cough Syrup DM Decongestant ExpectorantStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Cough Syrup DM Decongestant for ChildrenKsl Pharmaceuticals
Cough Syrup DM-D-EWestcan Pharmaceuticals Ltd.
Cough Syrup DM-D-E With AcetaminophenSupplements Aromatik Inc.
Cough Syrup DM-D-E With Acetaminophen Extra StrengthSupplements Aromatik Inc.
Cough Syrup With CodeineTeva Canada Limited
Cough, Cold & FluVita Health Products Inc
Cough, Cold & Flu Super StrengthThe Winning Combination Inc.
Cough, Cold and Flu Daytime CapletsVita Health Products Inc
Cough, Cold and Flu Nightime CapletsVita Health Products Inc
Cough, Cold and Flu Relief Complete Night Super StrengthPharmetics (2011) Inc
Cough, Cold and Flu Relief Day Super StrengthPharmetics (2011) Inc
Covan SyrupPharmascience Inc
Day & Night Combo PackThe Winning Combination Inc.
Day Relief Cold and Flu Liquid CapsulesBanner Pharmacaps (Canada) Ltd.
Day Time Liquid CapsIvax Pharmaceuticals Incorporated
Day Time Multi Symptom ReliefPharma Strides Canada Corporation
Day Time ReliefPharma Strides Canada Corporation
Day Time Relief Extra StrengthPharma Strides Canada Corporation
Daycap Cold & Sinus Liquid GelsAccucaps Industries Limited
Dayquil DProcter & Gamble Inc
Dayquil LiquicapsProcter & Gamble Inc
Dayquil Liquicaps - CapProcter & Gamble Inc
Dayquil Medicine - LiqProcter & Gamble Inc
Daytime 325 Liqua CapsJamp Pharma Corporation
Daytime Cold & Flu Liquid CapsulesVita Health Products Inc
Daytime Cold and Flu Liquid CapsulesBanner Pharmacaps (Canada) Ltd.
Daytime Cold and Flu ReliefPharmetics (2011) Inc
Daytime Cold Medication Liquid FastgelsVita Health Products Inc
Daytime Cold Relief CapletsPharmetics (2011) Inc
Daytime Cold Relief Extra Strength TabletsPharmetics (2011) Inc
Daytime Cold/flu ReliefPerrigo International
Daytime Cough. Cold. Flu Gel CapsulesApotex Inc., Private Label Division
Daytime Flu Relief Extra StrengthPharmetics (2011) Inc
Daytime Liqua CapsJamp Pharma Corporation
Daytime Liquid - LiqPerrigo International
Daytime Sinus Relief Extra Strength TabletsPharmetics (2011) Inc
Deltuss Dmx Cough Suppressant Nasal Decongestant Antihistamine Grape FlavorDeliz Pharmaceutical Corp
Deltuss Dp Nasal Decongestant Antihistamine Cherry FlavorDeliz Pharmaceutical Corp
Demdec SyrRougier Pharma Division Of Ratiopharm Inc
Desgen DM TabsKramer Novis
Despec-DM TabsInternatiional Ethical Labs
Despec-tabInternational Ethical Labs
Dexbrompherniramine Maleate and Pseudoephedrine Sulfate 6mg/120mgKvk Tech, Inc.
Dicel CDCentrix Pharmaceutical
Dimetane DxCreekwood Pharmaceuticals Inc.
Dimetapp Children's Cough and Cold LiquidWhitehall Robins Inc.
Dimetapp Cold and Sinus CapletsWhitehall Robins Inc.
Dimetapp Cough & Congestion LiquidWyeth Consumer Healthcare Inc.
Dimetapp Daytime Cold CapletsWyeth Consumer Healthcare Inc.
Dimetapp Daytime Cold Extra Strength CapletsPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
DM Plus Decongestant Cough SyrupTechnilab Pharma Inc.
DM Plus Decongestant Plus Expector.ex.st.syrTechnilab Pharma Inc.
DM Plus Decongestant Plus Expectorant Cough SyrupTechnilab Pharma Inc.
DM-D-expectorant Cough and Cold SyrupD.C. Labs Limited
DM-decongestant Children's SyrupTrillium Health Care Products Inc
DM-decongestant SyrupTrillium Health Care Products Inc
DM-decongestant-expectorant (extra Strength) SyrupTrillium Health Care Products Inc
DM-decongestant-expectorant SyrupTrillium Health Care Products Inc
Dristan Nd CapletsPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Dristan Non-drowsy Extra Strength CapletPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Dristan Sinus CapletsWhitehall Robins Inc.
Drixoral Cold & SinusBayer Inc Consumer Care
Drixoral Day/night - Srt/tabsSchering Plough Canada Inc
Drixoral SyrupSchering Plough Canada Inc
Drixtab TabSchering Plough Canada Inc
Dry Cough & Cold SyrupPharmetics (2011) Inc
DrymaxJay Mac Pharmaceuticals Llc
Drymax AFJay Mac Pharmaceuticals
DurafluPoly Pharmaceuticals, Inc.
Ed-A-hist PseEDWARDS PHARMACEUTICALS, INC.
Entex LAPurdue Pharma
Entex TWra Ser Pharmaceuticals, Llc
Entre-coughAcella Pharmaceuticals, LLC
Entre-SBrookstone Pharmaceuticals, Inc.
Ephed Plus SinusDickey Consumer Products DBA DMD
Equaline All Day Allergy DSupervalu Inc
Equaline Allergy and Congestion ReliefSupervalu Inc
Equaline Ibuprofen Cold and SinusSupervalu Inc
Equate Allergy Relief DWal Mart Stores Inc
Equate Daytime Liquid CapsulesIvax Pharmaceuticals Incorporated
Equate Ibuprofen Cold and SinusWal Mart Stores Inc
Equate Nighttime Liquid CapsulesIvax Pharmaceuticals Incorporated
Exefen DmxLarken Laboratories, Inc.
Expectorant DM Cough Extra Strength With DecongestantTanta Pharmaceuticals Inc
Extra Strength Allergy and Sinus ReliefPendopharm Division Of De Pharmascience Inc
Extra Strength Allergy Plus Sinus ReliefKsl Pharmaceuticals
Extra Strength Allergy Sinus MedicationStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Extra Strength Allergy TotalVita Health Products Inc
Extra Strength Cold Medication Daytime ReliefVita Health Products Inc
Extra Strength Cold Medication Daytime RlfStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Extra Strength Cold Medication Nighttime ReliefVita Health Products Inc
Extra Strength Cold Medication Nighttime RlfStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Extra Strength Cough Plus Cold Relief SyrupPharmetics (2011) Inc
Extra Strength Day and Night Cold MedicationPendopharm Division Of De Pharmascience Inc
Extra Strength Daytime Cold ReliefPendopharm Division Of De Pharmascience Inc
Extra Strength Daytime Cold Relief-capletKsl Pharmaceuticals
Extra Strength Flu Relief DaytimeVita Health Products Inc
Extra Strength Flu Relief NightimeVita Health Products Inc
Extra Strength Head Cold and SinusVita Health Products Inc
Extra Strength Neocitran Flu NightNovartis Consumer Health Canada Inc.
Extra Strength Neocitran Total NightNovartis Consumer Health Canada Inc.
Extra Strength Nighttime Cold ReliefPendopharm Division Of De Pharmascience Inc
Extra Strength Nighttime Cold Relief-capletKsl Pharmaceuticals
Extra Strength Sinus Medication-capletStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Extra Strength Sinus ReliefPendopharm Division Of De Pharmascience Inc
Extra Strength Sinus Relief DaytimeVita Health Products Inc
Extra Strength Sinus Relief NighttimeVita Health Products Inc
Extra Strength Sinus Relief-capletKsl Pharmaceuticals
Extra Strength Tylenol Allergy Sinus CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Allergy Sinus Nighttime CapletMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Cold & Sinus DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Cold & Sinus NighttimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Cold and Flu PowderMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Cold DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Cold Nighttime CapletMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Complete Cold, Cough & FluMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Complete Cold, Cough & Flu DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Complete Cold, Cough & Flu NighttimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Complete Cold, Cough & Flu Plus Mucus ReliefMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Complete Cold, Cough & Flu Plus Mucus Relief NighttimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Flu DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Flu Nighttime GelcapMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Sinus Pain and Congestion DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Extra Strength Tylenol Sinus Pain and Congestion NighttimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Fexofenadine HCl and Pseudoephedrine HciWalgreens Company
Fexofenadine HCl and Pseudoephedrine HClDr.Reddy's Laboratories Limited
Fexofenadine Hydrochloride and Pseudoephedrine HydrochlorideRebel Distributors Corp
Flu ReliefVita Health Products Inc
Flu, Cough & Cold CompleteVita Health Products Inc
Flu, Cough & Cold Complete Day and NightVita Health Products Inc
Formule 115 DMFrega Inc.
G-con-XMc Laren Medical
G-tuss-NLMc Laren Medical
G-tuss-NL PedMc Laren Medical
G-xpect PseMc Laren Medical
GlentussGlendale Inc
Good Neighbor Pharmacy All Day Allergy DAmerisource Bergen
Good Neighbor Pharmacy Childrens Ibuprofen ColdAmerisource Bergen
Good Neighbor Pharmacy Ibuprofen Cold and SinusAmerisource Bergen
Good Neighbor Pharmacy Loratadine DAmerisource Bergen
Good Neighbor Pharmacy Loratadine D 24 HourAmerisource Bergen
Good Neighbor Pharmacy Mucus DAmerisource Bergen
Good Neighbor Pharmacy Night Time DAmerisource Bergen
Good Neighbor Pharmacy Sinus and Cold DAmerisource Bergen
Good Sense All Day Allergy DL Perrigo Company
Good Sense Allergy and Congestion ReliefL Perrigo Company
Good Sense Allergy and Congestion Relief Non Drowsy 24 HourL Perrigo Company
Good Sense Ibuprofen Cold and SinusL Perrigo Company
Good Sense Mucus DL. Perrigo Company
GripmaxUnipharm, Inc.
Guaifenesin and Pseudoephedrine Hydrochloride Extended ReleasePerrigo New York Inc
Guaifenesin DacRising Pharmaceuticals
Harris Teeter All Day Allergy DHarris Teeter, LLC
Head Cold and Sinus Relief CapletsPharmetics (2011) Inc
Health Mart Allergy and CongestionMc Kesson
Health Mart Allergy Complete DMc Kesson
Health Mart Mucus Relief DMc Kesson
Health Mart Sinus and Cold DMc Kesson
Healthy Accents Allergy and Congestion Relief 24 Hour Non DrowsyDZA Brands LLC
Healthy Accents Cetirizine-DDZA Brands LLC
Histenol Cold TabletsZee Medical Inc
Hot Lemon Night Time Total Extra StrengthPharmetics (2011) Inc
Hot Lemon Relief for Sore Throat and Cough Extra StrengthJamp Pharma Corporation
Hot Lemon Relief for Symptoms Of Cough, Cold and FluPatheon Laboratories
Hot Lemon Relief for Symptoms Of Cough, Cold and Flu Extra StrengthPharmetics (2011) Inc
HycofenixMission Pharmacal Company
Hydrocodone Bitartrate and Pseudoephedrine Hydrochloride SolutionTris Pharma Inc
Hydrocodone Bitartrate, Chlorpheniramine Maleate and Pseudoephedrine HydrochloridePaddock Laboratories, LLC
Hydrocodone Bitartrate, Chlorpheniramine Maleate, and Pseudoephedrine HClCypress Pharmaceutical, Inc.
Hydrocodone Bitartrate, Chlorpheniramine Maleate, and Pseudoephedrine Hydrochloride Oral SolutionTris Pharma Inc
Ibu Profen Cold and SinusRite Aid Corporation
Ibuprofen + Pseudoephedrine CapletsInternational Pharmaceutical Generics Ltd
Ibuprofen and PseudoephedrineMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Ibuprofen and Pseudoephedrine HydrochlorideWalgreen Company
Ibuprofen Cold and SinusKroger Company
Ibuprofen Cold and Sinus A P JA P J Laboratories Limited
Ibuprofen Cold ChildrensMeijer Distribution Inc
Ibuprofen Cold Relief ChildrensCVS Pharmacy
Infants Tylenol Cold Suspension DropsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
J-cof DhcJay Mac Pharmaceuticals
J-tan D PdJay Mac Pharmaceuticals Llc
Jack & Jill Cough and ColdThe Buckley's Company
Jack & Jill Cough, Cold & Flu Junior Strength TabletsThe Buckley's Company
Junior Strength Cold DM - TabletVita Health Products Inc
Junior Strength Tylenol Cold and CoughMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Junior Strength Tylenol Complete Cold, Cough & FeverMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Junior Strength Tylenol Decongestant - TabMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Kidkare Cough/coldRugby Laboratories, Inc.
Kirkland Signature Aller Tec DCostco Wholesale Company
Kirkland Signature Allerclear D 12 HrCostco Wholesale Company
Kirkland Signature Allerclear D 24hrCostco Wholesale Company
Koffex DM + Decongestant SyrupTechnilab Pharma Inc.
Koffex DM + Decongestant + ExpectorantTechnilab Pharma Inc.
Koffex DM + Decongestant + Expectorant Extra StrengthTechnilab Pharma Inc.
Koffex DM-D-E - LiqRougier Pharma Division Of Ratiopharm Inc
Leader Allergy D 12Cardinal Health
Leader Allergy Relief D-24Cardinal Health
Leader Ibuprofen Cold and SinusCardinal Health
Leader Ibuprofen Cold ChildrensCardinal Health
Leader Sinus and Cold-DCardinal Health
LiberatorSchering Plough Canada Inc
Lodrane DECR Pharmaceuticals
Lohist DLarken Laboratories, Inc.
Loratadine and PseudoephedrineWalgreen Company
Loratadine and Pseudoephedrine SulfateMajor Pharmaceuticals
Loratadine DPerrigo New York Inc
Loratadine D 24 HourPerrigo New York Inc
Lortuss DMSallus Laboratories, Llc
Lortuss EXSallus Laboratories, Llc
Lortuss LqPoly Pharmaceuticals
M-end DMR.A. Mc Neil Company
M-end DmxR. A. Mc Neil Company
M-end Max DR.A. Mc Neil Company
M-end WcR.A. Mc Neil Company
Mar-cof BPMarnel Pharmaceutcals, Inc.
Maux De Gorge Et De LA Toux Extra-fortPharmalab Inc.
Maximum Strength Allergy SinusWALGREEN CO.
Medicament Pour Le Rhume, JourLaboratoire Riva Inc
Medicament Pour Le Rhume, NuitLaboratoire Riva Inc
Medicament Pour Les Sinus Reg CapletProdemdis Enr.
Medicament Pour Les Sinus, Extra-fortLaboratoire Riva Inc
Medicament Pour Les Sinus, RegulierLaboratoire Riva Inc
Medicament Sinus Personnel EX-fort CapletProdemdis Enr.
Medicament Sinus Personnel Reg CapletProdemdis Enr.
Medicine Shoppe Allergy Relief D24The Medicine Shoppe International
Motrin Cold & Sinus CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Motrin Cold & Sinus PainMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Mucinex DPhysicians Total Care, Inc.
Mucinex D Maximum StrengthReckitt Benckiser LLC
Mucus DMeijer Distribution Inc
Mucus Relief DWalgreen Company
Neo AcLaser Pharmaceuticals Llc
Neo Citran Daycaps Extra Strength - CapletNovartis Consumer Health Canada Inc.
Neo DMLaser Pharmaceuticals Llc
Neocitran Cold & Flu SyrupNovartis Consumer Health Canada Inc.
Neocitran Cough & Cold SyrupNovartis Consumer Health Canada Inc.
Neocitran Ultra Strength Total Flu NightNovartis Consumer Health Canada Inc.
Nicold Medicine for AdultsTanta Pharmaceuticals Inc
Night Relief Cold and Flu Liquid CapsulesBanner Pharmacaps (Canada) Ltd.
Night Time Cold and FluSafeway
Night Time Multi Symptom ReliefPharma Strides Canada Corporation
Night Time ReliefPharma Strides Canada Corporation
Night Time Total Extra StrengthPharmetics (2011) Inc
Nightcap Complete Liquid GelsAccucaps Industries Limited
Nighttime 325 Liqua CapsJamp Pharma Corporation
Nighttime Cold & Flu Liquid CapsulesVita Health Products Inc
Nighttime Cold & Flu Relief SyrupPharmetics (2011) Inc
Nighttime Cold and Flu Extra Strength MedicineJamp Pharma Corporation
Nighttime Cold and Flu Liquid CapsulesVita Health Products Inc
Nighttime Cold and Flu ReliefPharmetics (2011) Inc
Nighttime Cold and Flu-IN-one Extra StrengthVita Health Products Inc
Nighttime Cold Relief Extra Strength TabletsPharmetics (2011) Inc
Nighttime Cough. Cold. Flu Gel CapsulesApotex Inc., Private Label Division
Nighttime D Cold and FluHy Vee Inc
Nighttime D Cold and Flu ReliefWalgreen Company
Nighttime Flu, Cough & Cold Complete Relief Extra StrengthVita Health Products Inc
Nighttime Liqua CapsJamp Pharma Corporation
Nighttime Super Strength Contac CompleteGlaxosmithkline Consumer Healthcare Inc.
Nighttime Total Cold and FluVita Health Products Inc
Nighttime Total Super StrengthThe Winning Combination Inc.
Nite Time (children's)Perrigo International
NitetimeKroger Company
Nitetime Cold MedicineIvc Industries, Hall Division
Nitetime Cold Medicine LiqJamp Pharma Corporation
Nitetime Cold Medicine Original and CherryWestcan Pharmaceuticals Ltd.
Nitetime DMeijer Distribution Inc
Nitetime D Multi Symptom Cold Flu ReliefMeijer Distribution Inc
Non Drowsy Extra Strength Contac Cold Sore ThroatGlaxosmithkline Consumer Healthcare Inc.
Non Drowsy Regular Strength Contac Cold Chest CongestionGlaxosmithkline Consumer Healthcare Inc.
Non Drowsy Regular Strength Contac CompleteGlaxosmithkline Consumer Healthcare Inc.
Non Drowsy Super Strength Contac Cold Nasal CongestionGlaxosmithkline Consumer Healthcare Inc.
Non Drowsy Super Strength Contac CompleteGlaxosmithkline Consumer Healthcare Inc.
Notuss-nxdSj Pharmaceuticals, Llc
Novahistex DM Expectorant With DecongestantW.K. Buckley Ltd.
Novahistex DM With DecongestantW.K. Buckley Ltd.
Novahistex Expectorant With DecongestantHoechst Marion Roussel Canada Inc.
Novahistine DM Expectorant With DecongestantW.K. Buckley Ltd.
Novahistine DM With Decongestant - LiqW.K. Buckley Ltd.
Nyquil LiquicapsProcter & Gamble Inc
Once-A-day Benylin Cold CapKv Pharmaceutical Company
P.M. Cold Relief FormulaIvax Pharmaceuticals Incorporated
Pain & Fever + ColdAccudial Pharmaceutical Inc
Pain & Fever + Cold & CoughAccudial Pharmaceutical Inc
Pain & Fever + DecongestantAccudial Pharmaceutical Inc
Panatuss PedSeyer Pharmatec, Inc.
Pecgen Pse Cough Suppressant Expectorant Nasal Decongestant Grape FlavorKramer Novis
Pedia ReliefMajor Pharmaceuticals, Inc
Pediatric Cough and Cold MedicineSilarx Pharmaceuticals, Inc
Pediatric Cough SyrupTechnilab Pharma Inc.
Personnelle Contre Le Rhume LiqTherapex Division De E Z Em Canada Inc
Personnelle DM SyrTherapex Division De E Z Em Canada Inc
Phenylhistine DhQualitest Pharmaceuticals
Poly Hist NcPoly Pharmaceuticals, Inc.
Poly-tussin DPoly Pharmaceuticals
Poly-vent DMPoly Pharmaceuticals, Inc.
Poly-vent IrPoly Pharmaceuticals, Inc.
Preferred Plus Allergy and Congestion ReliefKinray
Preferred Plus Sinus and Cold DKinray
Prime's Sore Throat, Cough and Colds CapsulesPrime Health Ltd.
Promatussin DM Adult Formula SyrWyeth Ayerst Canada Inc.
Promatussin DM Children FormulaWyeth Ltd.
Pseudoephedrine PlusContract Pharmacal Corp
Q Tapp Cold and AllergyQualitest Pharmaceuticals
Q Tapp Cold and CoughQualitest Pharmaceuticals
Q-tappQualitest Pharmaceuticals
Q-tapp DM ElixirQualitest Pharmaceuticals
Ratio-cotridinTeva Canada Limited
Ratio-cotridin ExpectorantTeva Canada Limited
Reactine CompleteMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Reg.str.cold Medic.(night Time Relief)capletWestcan Pharmaceuticals Ltd.
Regular Strength Cold Medication(daytime R.)Westcan Pharmaceuticals Ltd.
Regular Strength Flu Relief NightimeVita Health Products Inc
Regular Strength Sinus MedicationWes Pak Products Ltd.
Regular Strength Sinus Medication-capletStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Regular Strength Tylenol Cold and Flu PowderMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Regular Strength Tylenol Cold Chest CongestionMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Regular Strength Tylenol Cold DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Regular Strength Tylenol Cold Nighttime CapletMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Regular Strength Tylenol Cough Suspension With DecongestantMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Regular Strength Tylenol Sinus CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Relievol Allergy Sinus Caplets Extra StrengthTanta Pharmaceuticals Inc
Relievol Sinus Caplets Extra Strength, Non Drowsy FormulaTanta Pharmaceuticals Inc
ResconCapellon Pharmaceuticals, LLC
Rescon DMCapellon Pharmaceuticals, LLC
Respaire-30Laser Pharmaceuticals, LLC
ReziraHawthorn Pharmaceuticals, Inc.
Robitussin Children's Cough and ColdPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robitussin Cough & Cold Extra StrengthPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robitussin Cough and ColdPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robitussin Cough and Cold Liqui-gelsWyeth Consumer Healthcare Inc.
Robitussin Cough, Cold & Flu Liqui-gelsWyeth Consumer Healthcare Inc.
Robitussin Honey Cough and ColdWhitehall Robins Inc.
Robitussin Honey FluWhitehall Robins Inc.
Robitussin Total Cough, Cold & FluPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robitussin Total Cough, Cold & Flu Extra StrengthPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
RydexCenturion Labs
Rynex PEEDWARDS PHARMACEUTICALS, INC.
Rynex PseEDWARDS PHARMACEUTICALS, INC.
Semprex DActient Pharmaceuticals, LLC
Severe Sinus CongestionWOONSOCKET PRESCRIPTION CENTER,INCORPORATED
Shoprite Allergy and Congestion ReliefWakefern Food Corporation
Shoprite Allergy D 12Wakefern Food Corporation
Signature Care Allergy and Congestion ReliefSafeway
Signature Care Allergy Relief DSafeway
SilafedSilarx Pharmaceuticals, Inc
Sinus and Allergy Regular StrengthPharmetics (2011) Inc
Sinus and Cold DL. Perrigo Company
Sinus Day/night Extra StrengthPharmetics (2011) Inc
Sinus MedicationVita Health Products Inc
Sinus Medication Day & NightVita Health Products Inc
Sinus Medication Day Regular TabletsPharmetics (2011) Inc
Sinus Medication Daytime ReliefVita Health Products Inc
Sinus Medication Extra Strength DaytimePharmascience Inc
Sinus Medication Extra Strength Night TimePharmascience Inc
Sinus Medication Night TabletsPharmetics (2011) Inc
Sinus Nighttime Extra Strength CapletsPharmetics (2011) Inc
Sinus Pain and Nasal Congestion ReliefVita Health Products Inc
Sinus ReliefVita Health Products Inc
Sinus Relief Extra Strength TabletJamp Pharma Corporation
Sinus Relief Nightime CapletsPharmetics (2011) Inc
Sinus Relief Regular Strength TabletJamp Pharma Corporation
Sinus Ultra Strength TabletJamp Pharma Corporation
Sinus, Pain & Nasal Congest Relief CapletWestcan Pharmaceuticals Ltd.
Sinusales Extra Fort NuitProdemdis Enr.
Sinutab Daytime/nightime Extra Strength Caplets (combo Pack)Mcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sinutab Extra Strength TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sinutab N.D.reg Strength TabMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sinutab N.T. Extra Strength CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sinutab N.T. Regular Strength CapletsWarner Lambert Canada Inc.
Sinutab Nd Extra Strength TabMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sinutab Regular Strength TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sinutab With Codeine TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Smart Sense All Day Allergy DKmart Corporation
Smart Sense Allergy and Congestion ReliefKmart Corporation
Smart Sense Allergy and Congestion Relief DKmart Corporation
Smart Sense Allergy and Congestion Relief Indoor and Outdoor AllergiesKmart Corporation
Smart Sense Allergy and Congestion Relief-DKmart Corporation
Smart Sense Allergy Relief DKmart Corporation
Sore Throat & Cough Ultra StrengthPharmascience Inc
Stahist AdMagna Pharmaceuticals, Inc.
Statuss GreenMagna Pharmaceuticals, Inc.
Sudafed 12 Hour Pressure and PainJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division
Sudafed Children's Sinus LiquidWarner Lambert Canada Inc.
Sudafed Cold and Cough Extra Strength CapletGlaxo Wellcome Inc.
Sudafed Cold and Cough Extra Strength CapletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sudafed Cold and Flu Gel CapsBurroughs Wellcome Inc., Consumer Prod Division
Sudafed DMGlaxo Wellcome Inc.
Sudafed Head Cold & Sinus Extra Strength TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sudafed Head Cold and Sinus Extra Strength CapletsGlaxo Wellcome Inc.
Sudafed Sinus & AllergyMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sudafed Sinus AdvanceMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sudafed Sinus DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Sudafed Sinus Extra StrengthBurroughs Wellcome Inc.
Sudafed Sinus NighttimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
SudogestMajor Pharmaceuticals
Sunmark All Day Allergy DMc Kesson
Sunmark Ibuprofen Cold and SinusMc Kesson
Sunmark Loratadine DMc Kesson
Sunmark Mucus Relief DMc Kesson
Sunmark Nite Time D Cold and FluMc Kesson
Sunmark Sinus and Cold DMc Kesson
Syrup DM-DTherapex Division De E Z Em Canada Inc
Syrup DM-D-ETherapex Division De E Z Em Canada Inc
Theraflu Flu Cold and Cough MedicineSandoz Canada Inc
Theraflu Max-DNovartis Consumer Health, Inc.
Topcare All Day Allergy DTopco Associates LLC
Topcare Allergy Relief DTopco Associates LLC
Topcare Ibuprofen Cold and SinusTopco Associates LLC
Topcare Nite Time DTopco Associates LLC
Topcare Sinus and Cold DTopco Associates LLC
Total Cold & FluPharmetics (2011) Inc
Total Cold & Flu ComboVita Health Products Inc
Total Cold and FluVita Health Products Inc
Total Cold and Flu Extra StrengthTrillium Health Care Products Inc
Total FluPharmetics (2011) Inc
Toux Rhume Et Grippe (extra-fort)Prodemdis Enr.
Triacin-CSTI Pharma LLC
Triaminic Cold & Nighttime CoughNovartis Consumer Health Canada Inc.
Triaminic Cold and AllergyNovartis Consumer Health Canada Inc.
Triaminic Cold and CoughNovartis Consumer Health Canada Inc.
Triaminic Cold Cough and FeverNovartis Consumer Health Canada Inc.
Triaminic CoughNovartis Consumer Health Canada Inc.
Triaminic Cough and CongestionNovartis Consumer Health Canada Inc.
Triaminic Cough and Sore ThroatNovartis Consumer Health Canada Inc.
Triaminic Decongest+expect Liqui-gels CapSandoz Canada Inc
Triaminic DM Expectorant SyrNovartis Consumer Health Canada Inc.
Triaminic DM Plus Decongestant SyrupSandoz Canada Inc
Triaminic DM+decongestant Liqui-gels CapsulesSandoz Canada Inc
Triaminic Expectorant SyrNovartis Consumer Health Canada Inc.
Triaminic Softchews Cold and AllergyNovartis Consumer Health Canada Inc.
Triaminic Softchews Cough and ColdNovartis Consumer Health Canada Inc.
Triaminic Softchews Throat Pain & CoughNovartis Consumer Health Canada Inc.
Triaminicol DM SyrupNovartis Consumer Health Canada Inc.
Tricode ArRespa Pharmaceuticals, Inc.
Tricode GfRespa Pharmaceuticals, Inc.
Trinalin RepetabsSchering Plough Canada Inc
Triprofed TabIcn Canada Ltd.
Trispec Pse Cough Suppressant Expectorant Nasal Decongestant Grape FlavorDeliz Pharmaceutical Corp
Trispec Pse Pediatric Drops Cough Suppressant Expectorant Nasal Decongestant Grape FlavorDeliz Pharmaceutical Corp
TusnelLlorens Pharmaceutical International Division
Tusnel CLlorens Pharmaceutical International Division
Tusnel DM PediatricLlorens Pharmaceutical International Division
Tusnel PediatricLlorens Pharmaceutical International Division
Tussilyn DMLes Laboratoires Vachon Inc.
Tussin Cough Medicine DM Antitussive Expectorant DecongestantStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Tussodan DM SyrupOdan Laboratories Ltd
Tylenol Cold & Flu DaytimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Tylenol Cold & Flu NighttimeMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Tylenol Complete Cold, Cough & FluMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Tylenol Sinus Plus Mucous ReliefMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Ultra Strength Neocitran Flu Day With Mucus ReliefNovartis Consumer Health Canada Inc.
Ultra Strength Neocitran Total FluNovartis Consumer Health Canada Inc.
Up and Up All Day Allergy Relief DTarget Corporation
Up and Up Allergy and Congestion ReliefTarget Corporation
Up and Up Allergy Plus Congestion Relief DTarget Corporation
Up and Up Cold and SinusTarget Corporation
Up and Up Sinus and Cold DTarget Corporation
VanacofGm Pharmaceuticals
VasofrinicLaboratoires Trianon Inc
Vasofrinic DhLaboratoires Trianon Inc
Vasofrinic Plus SiropLaboratoires Trianon Inc
Vasofrinic SiropLaboratoires Trianon Inc
Vicks Dayquil LiquicapsProcter & Gamble Inc
Vicks Dayquil Sinus LiquicapsProcter & Gamble Inc
Vicks Dayquil Sinus Pr.and Pain ReL.W.ibupr.Procter & Gamble Inc
Vicks Formula 44d LiqProcter & Gamble Inc
Vicks Formula 44m LiqProcter & Gamble Inc
Vicks Nyquil Adult Nighttime Colds MedicineProcter & Gamble Inc
Vicks Nyquil D Cold and Flu Nighttime ReliefThe Procter & Gamble Manufacturing Company
Vicks Nyquil LiquicapsProcter & Gamble Inc
Vicks Nyquil Sinus LiquicapsProcter & Gamble Inc
Vicks Pediatric Formula 44d LiqProcter & Gamble Inc
Vicks Pediatric Formula 44m LiqProcter & Gamble Inc
Virtussin DacVirtus Pharmaceuticals
Viva Cold & Flu All In One Relief CapletsViva Pharmaceutical Inc.
Wal Itin DWalgreen Company
Wal Itin D 12 Hour Allergy and CongestionWalgreen Company
Wal Itin D Non DrowsyWalgreen Company
Wal Itin D Non Drowsy 24 Hour Allergy and CongestionWalgreen Company
Wal Profen Cold and SinusWalgreen Company
Wal Zyr DWalgreen Company
Wal Zyr D Allergy and CongestionWalgreen Company
Wal-actWALGREEN CO.
Wal-finate DWALGREEN CO.
Wal-itin D 24 HourWalgreen Company
Wal-phedWALGREEN CO.
Z-tuss EMagna Pharmaceuticals, Inc.
Zodryl Dec 25Coda Dose, Inc.
Zodryl Dec 30Coda Dose, Inc.
Zodryl Dec 40Coda Dose, Inc.
Zodryl Dec 50Coda Dose, Inc.
Zodryl Dec 60Coda Dose, Inc.
Zodryl Dec 80Coda Dose, Inc.
ZutriproHawthorn Pharmaceuticals, Inc.
Zyrtec D Allergy and CongestionPhysicians Total Care, Inc.
Zyrtec-D Allergy and CongestionJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division
Salts
Name/CASStructureProperties
Pseudoephedrine hydrochloride
345-78-8
Thumb
  • InChI Key: BALXUFOVQVENIU-KXNXZCPBSA-N
  • Monoisotopic Mass: 201.092041846
  • Average Mass: 201.693
DBSALT000149
Pseudoephedrine sulfate
Thumb
  • InChI Key: XVPDSDYVNYOVMP-KXNXZCPBSA-N
  • Monoisotopic Mass: 263.082743349
  • Average Mass: 263.311
DBSALT000150
Categories
UNII7CUC9DDI9F
CAS number90-82-4
WeightAverage: 165.2322
Monoisotopic: 165.115364107
Chemical FormulaC10H15NO
InChI KeyInChIKey=KWGRBVOPPLSCSI-WCBMZHEXSA-N
InChI
InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m0/s1
IUPAC Name
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
SMILES
CN[C@@H](C)[C@@H](O)C1=CC=CC=C1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as phenylpropanes. These are organic compounds containing a phenylpropane moiety.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassPhenylpropanes
Direct ParentPhenylpropanes
Alternative Parents
Substituents
  • Phenylpropane
  • Aralkylamine
  • Secondary alcohol
  • 1,2-aminoalcohol
  • Secondary amine
  • Secondary aliphatic amine
  • Hydrocarbon derivative
  • Aromatic alcohol
  • Organooxygen compound
  • Organonitrogen compound
  • Amine
  • Alcohol
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Pharmacology
IndicationFor the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism.
PharmacodynamicsPseudoephedrine is a sympathomimetic agent, structurally similar to ephedrine, used to relieve nasal and sinus congestion and reduce air-travel-related otalgia in adults. The salts pseudoephedrine hydrochloride and pseudoephedrine sulfate are found in many over-the-counter preparations either as single-ingredient preparations, or more commonly in combination with antihistamines and/or paracetamol/ibuprofen. Unlike antihistamines, which modify the systemic histamine-mediated allergic response, pseudoephedrine only serves to relieve nasal congestion commonly associated with colds or allergies. The advantage of oral pseudoephedrine over topical nasal preparations, such as oxymetazoline, is that it does not cause rebound congestion (rhinitis medicamentosa).
Mechanism of actionPseudoephedrine acts directly on both alpha- and, to a lesser degree, beta-adrenergic receptors. Through direct action on alpha-adrenergic receptors in the mucosa of the respiratory tract, pseudoephedrine produces vasoconstriction. Pseudoephedrine relaxes bronchial smooth muscle by stimulating beta2-adrenergic receptors. Like ephedrine, pseudoephedrine releasing norepinephrine from its storage sites, an indirect effect. This is its main and direct mechanism of action. The displaced noradrenaline is released into the neuronal synapse where it is free to activate the postsynaptic adrenergic receptors.
Related Articles
AbsorptionPseudoephedrine is readily and almost completely absorbed from the GI tract and there is no evidence of first-pass metabolism.
Volume of distributionNot Available
Protein bindingPseudoephedrine does not bind to human plasma proteins over the concentration range of 50 to 2000 ng/mL
Metabolism

Hepatic.

Route of eliminationNot Available
Half life9-16 hours
ClearanceNot Available
ToxicityCommon adverse reactions include nervousness, restlessness, and insomnia. Rare adverse reactions include difficult/painful urination, dizziness/lightheadedness, heart palpitations, headache, increased sweating, nausea/vomiting, trembling, troubled breathing, unusual paleness, and weakness.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9645
Blood Brain Barrier+0.5638
Caco-2 permeable+0.8866
P-glycoprotein substrateNon-substrate0.7182
P-glycoprotein inhibitor INon-inhibitor0.9795
P-glycoprotein inhibitor IINon-inhibitor0.984
Renal organic cation transporterNon-inhibitor0.8965
CYP450 2C9 substrateNon-substrate0.8001
CYP450 2D6 substrateNon-substrate0.7839
CYP450 3A4 substrateNon-substrate0.7235
CYP450 1A2 substrateNon-inhibitor0.5595
CYP450 2C9 inhibitorNon-inhibitor0.7209
CYP450 2D6 inhibitorInhibitor0.5846
CYP450 2C19 inhibitorNon-inhibitor0.5737
CYP450 3A4 inhibitorNon-inhibitor0.9431
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.907
Ames testNon AMES toxic0.9517
CarcinogenicityNon-carcinogens0.7739
BiodegradationNot ready biodegradable0.7807
Rat acute toxicity2.3882 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9329
hERG inhibition (predictor II)Non-inhibitor0.9277
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Ucb inc
  • Schering plough healthcare products inc
Packagers
Dosage forms
FormRouteStrength
Capsule, liquid filledoral
Tablet, film coatedoral
Tablet (extended-release)oral
Syruporal7.5 mg
Syruporal
Suspensionoral
Solutionoral15 mg/5mL
Tablet, extended releaseoral
Tablet (immediate and extended release)oral
Kit; capsuleoral
Solutionoral
Tabletoral30 mg
Capsule (sustained-release)oral120 mg
Pilloral30 mg/1
Kit; powder for solutionoral
Tablet (extended-release); tabletoral
Tablet (extended-release)oral120 mg
Liquidoral60 mg/60mL
Package; powderoral
Tablet, sugar coatedoral
Tablet, film coatedoral30 mg/1
Tablet, film coated, extended releaseoral120 mg/1
Powderoral
Liquidoral
Tablet, coatedoral
Tablet (chewable)oral
Capsuleoral
Tablet, film coated, extended releaseoral
Tabletoral120 mg
Capsule (sustained-release)oral240 mg
Tabletoral30 mg/1
Tablet, sugar coatedoral30 mg/1
Capsule (sustained-release)oral
Solution/ dropsoral
Tablet, extended releaseoral120 mg/1
Tablet, film coatedoral120 mg/1
Tabletoral60 mg/1
Tabletoral60 mg
Elixiroral
Tablet, multilayeroral
Liquidoral30 mg/5mL
Kit; tabletoral
Tablet, extended releaseoral240 mg/1
Tabletoral15 mg
Syruporal30 mg
Liquidoral15 mg/5mL
Tablet, coatedoral30 mg/1
Tablet, film coatedoral60 mg/1
Powder, for solutionoral
Liquidoral30 mg
Liquidoral7.5 mg
Powder for solutionoral
Tabletoral
Prices
Unit descriptionCostUnit
Sudafed 24 hour tablet0.84USD tablet
Pseudoephedrine hcl crystal0.67USD g
Afrin 0.05% nose spray0.62USD ml
Sudafed 12 hr sinus-pain caplet0.53USD caplet
Drixoral cold & allergy tablet sa0.4USD tablet
Sudafed om sinus nasal spray0.4USD ml
Afrin no drip sinus pump mist0.38USD ml
Sudafed pe cold & cough caplet0.34USD caplet
Afrin sinus spray0.33USD ml
Chlor-trimeton allergy0.31USD each
Sudafed pe severe cold caplet0.28USD caplet
Guaifenesin-phenylephrine tablet0.27USD tablet
Dimetapp cold-allergy tablet chew0.25USD tablet
Sudafed pe 10 mg tablet0.25USD tablet
Chlor-trimeton 8 mg repetab0.24USD tablet
Sudafed pe day & night tablet0.24USD tablet
Sudafed triple action caplet0.23USD caplet
Sudafed pe nighttime cold caplet0.22USD caplet
Sudafed non-drying sinus caplet0.2USD caplet
Sudafed pe sinus & allergy tablet0.2USD tablet
Sudafed pe sinus headache caplet0.2USD caplet
Sudafed 30 mg tablet0.19USD tablet
Wal-phed 30 mg tablet0.17USD tablet
Suphedrin 30 mg tablet0.15USD tablet
CVS Pharmacy decongestant 30 mg tablet0.12USD tablet
Sudogest 60 mg tablet0.12USD tablet
Medi-phedrine 30 mg tablet0.1USD tablet
Nasal decongestant 30 mg tablet0.1USD tablet
Genaphed plus tablet0.09USD tablet
CVS Pharmacy nasal decongest 30 mg tablet0.07USD tablet
Genaphed 30 mg tablet0.07USD tablet
Pseudoephedrine gg syrup0.07USD ml
Pseudoephedrine 60 mg tablet0.06USD tablet
Children's sudafed pe liquid0.05USD ml
Pseudoephedrine 30 mg tablet0.05USD tablet
Dimetapp cold & cough liquid0.04USD ml
Dimetapp dm cold & cough elix0.04USD ml
Dimetapp long-acting cough liquid0.04USD ml
Suphedrine 30 mg tablet0.04USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US5855912 Yes1995-08-282015-08-28Us
US6037353 Yes1997-09-142017-09-14Us
US6039974 No1998-07-312018-07-31Us
US6100274 Yes2000-01-072020-01-07Us
US6113942 Yes1995-08-282015-08-28Us
US6211246 No1999-06-102019-06-10Us
US6372252 No2000-04-282020-04-28Us
US6469009 No1999-07-132019-07-13Us
US6489329 No1996-04-082016-04-08Us
US6613357 No2000-12-252020-12-25Us
US6709676 No2001-02-182021-02-18Us
US6955821 No2000-04-282020-04-28Us
US6979463 No2002-03-282022-03-28Us
US7014867 No2002-06-102022-06-10Us
US7226614 No2002-06-102022-06-10Us
US7618649 Yes2001-06-192021-06-19Us
US7820199 Yes2002-09-282022-09-28Us
US7838032 No2000-04-282020-04-28Us
US7863287 No2007-02-282027-02-28Us
US8187630 No2000-12-192020-12-19Us
USRE39069 No1998-05-292018-05-29Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point119 °CPhysProp
water solubility7 mg/LNot Available
logP0.89KRIL,MB & FUNG,HL (1990)
pKa10.3 (at 0 °C)PERRIN,DD (1965)
Predicted Properties
PropertyValueSource
Water Solubility8.26 mg/mLALOGPS
logP1ALOGPS
logP1.32ChemAxon
logS-1.3ALOGPS
pKa (Strongest Acidic)13.89ChemAxon
pKa (Strongest Basic)9.52ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area32.26 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity49.69 m3·mol-1ChemAxon
Polarizability18.83 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Download (8.24 KB)
Spectra
Spectrum TypeDescriptionSplash Key
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, N/A (Annotated)splash10-016s-3900000000-868bf4bba93d8b4be696View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, N/A (Annotated)splash10-0159-2900000000-6c55fc67b7576cb42a8aView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, N/A (Annotated)splash10-0006-9700000000-459686cbaf7d3b59c202View in MoNA
MSMass Spectrum (Electron Ionization)splash10-0a4i-9000000000-8f0484f72b48017f1f2eView in MoNA
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

Andrew G. Myers, “Synthesis of l-azatyrosine using pseudoephedrine as a chiral auxiliary.” U.S. Patent US5760237, issued June, 1991.

US5760237
General ReferencesNot Available
External Links
ATC CodesR01BA02R01BA52
AHFS Codes
  • 12:12.12
PDB EntriesNot Available
FDA labelNot Available
MSDSDownload (52.7 KB)
Interactions
Drug Interactions
Drug
AcebutololThe risk or severity of adverse effects can be increased when Acebutolol is combined with Pseudoephedrine.
AcetazolamideThe serum concentration of Pseudoephedrine can be increased when it is combined with Acetazolamide.
AlfuzosinAlfuzosin may decrease the vasoconstricting activities of Pseudoephedrine.
Ammonium chlorideThe serum concentration of Pseudoephedrine can be decreased when it is combined with Ammonium chloride.
AmphetamineThe risk or severity of adverse effects can be increased when Amphetamine is combined with Pseudoephedrine.
AtomoxetineAtomoxetine may increase the hypertensive activities of Pseudoephedrine.
BenzphetamineThe risk or severity of adverse effects can be increased when Benzphetamine is combined with Pseudoephedrine.
Benzylpenicilloyl PolylysinePseudoephedrine may decrease effectiveness of Benzylpenicilloyl Polylysine as a diagnostic agent.
CabergolineCabergoline may increase the hypertensive activities of Pseudoephedrine.
Calcium AcetateThe serum concentration of Pseudoephedrine can be increased when it is combined with Calcium Acetate.
ChlorphentermineThe risk or severity of adverse effects can be increased when Chlorphentermine is combined with Pseudoephedrine.
ClenbuterolThe risk or severity of adverse effects can be increased when Clenbuterol is combined with Pseudoephedrine.
DiclofenamideThe serum concentration of Pseudoephedrine can be increased when it is combined with Diclofenamide.
DobutamineThe risk or severity of adverse effects can be increased when Dobutamine is combined with Pseudoephedrine.
DopamineThe risk or severity of adverse effects can be increased when Dopamine is combined with Pseudoephedrine.
DoxofyllineThe risk or severity of adverse effects can be increased when Pseudoephedrine is combined with Doxofylline.
DronabinolDronabinol may increase the tachycardic activities of Pseudoephedrine.
EpinephrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Pseudoephedrine.
EthoxzolamideThe serum concentration of Pseudoephedrine can be increased when it is combined with Ethoxzolamide.
FenoterolThe risk or severity of adverse effects can be increased when Fenoterol is combined with Pseudoephedrine.
FentanylThe serum concentration of Fentanyl can be decreased when it is combined with Pseudoephedrine.
FormoterolThe risk or severity of adverse effects can be increased when Formoterol is combined with Pseudoephedrine.
IobenguaneThe therapeutic efficacy of Iobenguane can be decreased when used in combination with Pseudoephedrine.
IsoprenalineThe risk or severity of adverse effects can be increased when Isoprenaline is combined with Pseudoephedrine.
LabetalolThe risk or severity of adverse effects can be increased when Labetalol is combined with Pseudoephedrine.
LinezolidLinezolid may increase the hypertensive activities of Pseudoephedrine.
MephentermineThe risk or severity of adverse effects can be increased when Mephentermine is combined with Pseudoephedrine.
MetaraminolThe risk or severity of adverse effects can be increased when Metaraminol is combined with Pseudoephedrine.
MethamphetamineThe risk or severity of adverse effects can be increased when Methamphetamine is combined with Pseudoephedrine.
MethoxamineThe risk or severity of adverse effects can be increased when Methoxamine is combined with Pseudoephedrine.
MidodrineThe risk or severity of adverse effects can be increased when Midodrine is combined with Pseudoephedrine.
NaphazolineThe risk or severity of adverse effects can be increased when Naphazoline is combined with Pseudoephedrine.
NorepinephrineThe risk or severity of adverse effects can be increased when Norepinephrine is combined with Pseudoephedrine.
OrciprenalineThe risk or severity of adverse effects can be increased when Orciprenaline is combined with Pseudoephedrine.
OxymetazolineThe risk or severity of adverse effects can be increased when Oxymetazoline is combined with Pseudoephedrine.
PhenelzinePhenelzine may increase the hypertensive activities of Pseudoephedrine.
PhenmetrazineThe risk or severity of adverse effects can be increased when Phenmetrazine is combined with Pseudoephedrine.
PhentermineThe risk or severity of adverse effects can be increased when Phentermine is combined with Pseudoephedrine.
PhenylephrineThe risk or severity of adverse effects can be increased when Phenylephrine is combined with Pseudoephedrine.
PhenylpropanolamineThe risk or severity of adverse effects can be increased when Phenylpropanolamine is combined with Pseudoephedrine.
PrazosinPrazosin may decrease the vasoconstricting activities of Pseudoephedrine.
RitodrineThe risk or severity of adverse effects can be increased when Ritodrine is combined with Pseudoephedrine.
SalmeterolThe risk or severity of adverse effects can be increased when Salmeterol is combined with Pseudoephedrine.
SpironolactoneSpironolactone may decrease the vasoconstricting activities of Pseudoephedrine.
Tedizolid PhosphateTedizolid Phosphate may increase the hypertensive activities of Pseudoephedrine.
TerbutalineThe risk or severity of adverse effects can be increased when Terbutaline is combined with Pseudoephedrine.
TranylcypromineTranylcypromine may increase the hypertensive activities of Pseudoephedrine.
VenlafaxineVenlafaxine may increase the tachycardic activities of Pseudoephedrine.
Food Interactions
  • Take without regard to meals.

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Norepinephrine:sodium symporter activity
Specific Function:
Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
Gene Name:
SLC6A2
Uniprot ID:
P23975
Molecular Weight:
69331.42 Da
References
  1. Wee S, Ordway GA, Woolverton WL: Reinforcing effect of pseudoephedrine isomers and the mechanism of action. Eur J Pharmacol. 2004 Jun 16;493(1-3):117-25. [PubMed:15189772 ]
  2. Foley KF, Van Dort ME, Sievert MK, Ruoho AE, Cozzi NV: Stereospecific inhibition of monoamine uptake transporters by meta-hydroxyephedrine isomers. J Neural Transm (Vienna). 2002 Oct;109(10):1229-40. [PubMed:12373557 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Monoamine transmembrane transporter activity
Specific Function:
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Gene Name:
SLC6A3
Uniprot ID:
Q01959
Molecular Weight:
68494.255 Da
References
  1. Wee S, Ordway GA, Woolverton WL: Reinforcing effect of pseudoephedrine isomers and the mechanism of action. Eur J Pharmacol. 2004 Jun 16;493(1-3):117-25. [PubMed:15189772 ]
  2. Foley KF, Van Dort ME, Sievert MK, Ruoho AE, Cozzi NV: Stereospecific inhibition of monoamine uptake transporters by meta-hydroxyephedrine isomers. J Neural Transm (Vienna). 2002 Oct;109(10):1229-40. [PubMed:12373557 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
agonist
General Function:
Protein heterodimerization activity
Specific Function:
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.
Gene Name:
ADRA1A
Uniprot ID:
P35348
Molecular Weight:
51486.005 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Wellington K, Jarvis B: Cetirizine/pseudoephedrine. Drugs. 2001;61(15):2231-40; discussion 2241-2. [PubMed:11772135 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
agonist
General Function:
Thioesterase binding
Specific Function:
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianser...
Gene Name:
ADRA2A
Uniprot ID:
P08913
Molecular Weight:
48956.275 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Serotonin:sodium symporter activity
Specific Function:
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin an...
Gene Name:
SLC6A4
Uniprot ID:
P31645
Molecular Weight:
70324.165 Da
References
  1. Wee S, Ordway GA, Woolverton WL: Reinforcing effect of pseudoephedrine isomers and the mechanism of action. Eur J Pharmacol. 2004 Jun 16;493(1-3):117-25. [PubMed:15189772 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
partial agonist
General Function:
Protein homodimerization activity
Specific Function:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Gene Name:
ADRB2
Uniprot ID:
P07550
Molecular Weight:
46458.32 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Vansal SS, Feller DR: Direct effects of ephedrine isomers on human beta-adrenergic receptor subtypes. Biochem Pharmacol. 1999 Sep 1;58(5):807-10. [PubMed:10449190 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonistpartial agonist
General Function:
Receptor signaling protein activity
Specific Function:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.
Gene Name:
ADRB1
Uniprot ID:
P08588
Molecular Weight:
51322.1 Da
References
  1. Vansal SS, Feller DR: Direct effects of ephedrine isomers on human beta-adrenergic receptor subtypes. Biochem Pharmacol. 1999 Sep 1;58(5):807-10. [PubMed:10449190 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Transcriptional activator activity, rna polymerase ii distal enhancer sequence-specific binding
Specific Function:
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.
Gene Name:
NFATC1
Uniprot ID:
O95644
Molecular Weight:
101241.73 Da
References
  1. Fiebich BL, Collado JA, Stratz C, Valina C, Hochholzer W, Munoz E, Bellido LM: Pseudoephedrine inhibits T-cell activation by targeting NF-kappaB, NFAT and AP-1 signaling pathways. Immunopharmacol Immunotoxicol. 2012 Feb;34(1):98-106. doi: 10.3109/08923973.2011.582118. Epub 2011 Jun 2. [PubMed:21631396 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Tumor necrosis factor receptor binding
Specific Function:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs ...
Gene Name:
TNF
Uniprot ID:
P01375
Molecular Weight:
25644.15 Da
References
  1. Wu Z, Kong X, Zhang T, Ye J, Fang Z, Yang X: Pseudoephedrine/ephedrine shows potent anti-inflammatory activity against TNF-alpha-mediated acute liver failure induced by lipopolysaccharide/D-galactosamine. Eur J Pharmacol. 2014 Feb 5;724:112-21. doi: 10.1016/j.ejphar.2013.11.032. Epub 2013 Dec 21. [PubMed:24365491 ]
  2. Fiebich BL, Collado JA, Stratz C, Valina C, Hochholzer W, Munoz E, Bellido LM: Pseudoephedrine inhibits T-cell activation by targeting NF-kappaB, NFAT and AP-1 signaling pathways. Immunopharmacol Immunotoxicol. 2012 Feb;34(1):98-106. doi: 10.3109/08923973.2011.582118. Epub 2011 Jun 2. [PubMed:21631396 ]
10. Nuclear factor kappa-light-chain-enhancer of activated B cells
Kind
Protein
Organism
Human
Pharmacological action
unknown
References
  1. Fiebich BL, Collado JA, Stratz C, Valina C, Hochholzer W, Munoz E, Bellido LM: Pseudoephedrine inhibits T-cell activation by targeting NF-kappaB, NFAT and AP-1 signaling pathways. Immunopharmacol Immunotoxicol. 2012 Feb;34(1):98-106. doi: 10.3109/08923973.2011.582118. Epub 2011 Jun 2. [PubMed:21631396 ]
Kind
Protein group
Organism
Human
Pharmacological action
unknown
General Function:
Transcriptional activator activity, rna polymerase ii transcription regulatory region sequence-specific binding
Specific Function:
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Components:
NameUniProt IDDetails
Cyclic AMP-dependent transcription factor ATF-1P18846 Details
Cyclic AMP-dependent transcription factor ATF-2P15336 Details
Cyclic AMP-dependent transcription factor ATF-3P18847 Details
Cyclic AMP-dependent transcription factor ATF-4P18848 Details
Cyclic AMP-dependent transcription factor ATF-5Q9Y2D1 Details
Cyclic AMP-dependent transcription factor ATF-6 alphaP18850 Details
Cyclic AMP-dependent transcription factor ATF-7P17544 Details
Jun dimerization protein 2Q8WYK2 Details
Proto-oncogene c-FosP01100 Details
Transcription factor AP-1P05412 Details
References
  1. Fiebich BL, Collado JA, Stratz C, Valina C, Hochholzer W, Munoz E, Bellido LM: Pseudoephedrine inhibits T-cell activation by targeting NF-kappaB, NFAT and AP-1 signaling pathways. Immunopharmacol Immunotoxicol. 2012 Feb;34(1):98-106. doi: 10.3109/08923973.2011.582118. Epub 2011 Jun 2. [PubMed:21631396 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Kinase activator activity
Specific Function:
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
Gene Name:
IL2
Uniprot ID:
P60568
Molecular Weight:
17627.52 Da
References
  1. Fiebich BL, Collado JA, Stratz C, Valina C, Hochholzer W, Munoz E, Bellido LM: Pseudoephedrine inhibits T-cell activation by targeting NF-kappaB, NFAT and AP-1 signaling pathways. Immunopharmacol Immunotoxicol. 2012 Feb;34(1):98-106. doi: 10.3109/08923973.2011.582118. Epub 2011 Jun 2. [PubMed:21631396 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Serotonin binding
Specific Function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Gene Name:
MAOA
Uniprot ID:
P21397
Molecular Weight:
59681.27 Da
References
  1. Ulus IH, Maher TJ, Wurtman RJ: Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochem Pharmacol. 2000 Jun 15;59(12):1611-21. [PubMed:10799660 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
Gene Name:
CYP2D6
Uniprot ID:
P10635
Molecular Weight:
55768.94 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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Drug created on June 13, 2005 07:24 / Updated on June 25, 2016 03:05