This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Tuaminoheptane is a vasoconstrictor nasal decongestant.
- Generic Name
- Tuaminoheptane
- DrugBank Accession Number
- DB13238
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Tuaminoheptane (DB13238)
- Weight
- Average: 115.22
Monoisotopic: 115.136099551 - Chemical Formula
- C7H17N
- Synonyms
- 1-Methylhexylamine
- 2-Aminoheptane
- 2-Heptanamine
- 2-Heptylamine
- Tuaminoheptane
- Tuaminoheptano
- Tuaminoheptanum
- External IDs
- BRN 0635676
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Purulent discharge acute rhinitis Combination Product in combination with: Acetylcysteine (DB06151) •••••••••••• ••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareOxymetazoline The absorption of Tuaminoheptane can be decreased when combined with Oxymetazoline. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Tuaminoheptane sulfate WZK5LN5CNW 6411-75-2 XKUUMWKWUZRRPD-UHFFFAOYSA-N - International/Other Brands
- Heptadrine / Heptin / Tuamine
Categories
- ATC Codes
- R01AA11 — Tuaminoheptane
- R01AA — Sympathomimetics, plain
- R01A — DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- R01 — NASAL PREPARATIONS
- R — RESPIRATORY SYSTEM
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as monoalkylamines. These are organic compounds containing an primary aliphatic amine group.
- Kingdom
- Organic compounds
- Super Class
- Organic nitrogen compounds
- Class
- Organonitrogen compounds
- Sub Class
- Amines
- Direct Parent
- Monoalkylamines
- Alternative Parents
- Organopnictogen compounds / Hydrocarbon derivatives
- Substituents
- Aliphatic acyclic compound / Hydrocarbon derivative / Organopnictogen compound / Primary aliphatic amine
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Z0420GYD84
- CAS number
- 123-82-0
- InChI Key
- VSRBKQFNFZQRBM-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H17N/c1-3-4-5-6-7(2)8/h7H,3-6,8H2,1-2H3
- IUPAC Name
- heptan-2-amine
- SMILES
- CCCCCC(C)N
References
- General References
- External Links
- KEGG Drug
- D07371
- ChemSpider
- 5401
- ChEBI
- 134753
- ChEMBL
- CHEMBL123693
- Wikipedia
- Tuaminoheptane
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Spray Nasal - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 3.29 mg/mL ALOGPS logP 2.46 ALOGPS logP 2 Chemaxon logS -1.5 ALOGPS pKa (Strongest Basic) 10.43 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 26.02 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 37.41 m3·mol-1 Chemaxon Polarizability 15.63 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 132.35893 predictedDeepCCS 1.0 (2019) [M+H]+ 134.45894 predictedDeepCCS 1.0 (2019) [M+Na]+ 143.09901 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:38 / Updated at June 05, 2021 09:13