Organometallic Compounds

A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
DrugDrug NameDrug Description
DB00113Technetium Tc-99m arcitumomabFor imaging colorectal tumors
DB00225GadodiamideA gadolinium-based contrast agent used for the visualization of lesions with vascularity during magnetic resonance imaging (MRI) scans.
DB00325NitroprussideA direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
DB00526OxaliplatinA platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.
DB00534ChlormerodrinPreviously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool.
DB00789Gadopentetic acidA gadolinium compound used as a contrast agent in MRIs.
DB00893Iron DextranAn iron supplement used to treat iron deficiency in patients who cannot take oral iron.
DB00958CarboplatinA alkylating agent used to treat advanced ovarian cancer.
DB00995AuranofinAn antirheumatic used to treat active, progressive, or destructive forms of inflammatory arthritis.
DB01169Arsenic trioxideA chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.
DB01592IronAn essential element commonly used for the treatment of patients with documented iron deficiency.
DB03006Arsanilic acidAn arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
DB04874PicoplatinFor the treatment of patients with solid tumors.
DB04992AP5346For the treatment of various forms of cancer.
DB04996SatraplatinInvestigated for use/treatment in lung cancer, prostate cancer, and solid tumors.
DB05112AP5280Investigated for use/treatment in solid tumors.
DB05488Technetium Tc-99m ciprofloxacinInvestigated for use/treatment in infectious and parasitic disease (unspecified).
DB05630Sodium stibogluconateFor the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment...
DB06179DarinaparsinInvestigated for use/treatment in blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), solid tumors, multiple myeloma, and liver cancer.
DB06215FerumoxytolAn intravenous iron replacement product used to treat iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD), or in patients who are unable to tolerate or who have not responded adequately to oral iron supplementation.
DB06783Prussian blueA chelating agent used to reduce the extent of systemic contamination with radioactive cesium and/or radioactive or non-radioactive thallium.
DB08857Bamet-UD2Bamet-UD2 is a novel bile acid-platinum derivative.
DB08858cis-Diamminechlorocholylglycinateplatinum(II)Not Annotated
DB08884Gadoxetic acidA gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver.
DB08917Ferric carboxymaltoseAn iron replacement therapy used to treat iron deficiency anemia in adults with intolerance or inadequate clinical response to oral iron or those who have non-dialysis dependent chronic kidney disease.
DB08928ArsthinolAntiprotozoal agent effective against amoebiasis and yaws.
DB09121AurothioglucoseA gold compound used in the treatment of rheumatoid arthritis.
DB09137Technetium Tc-99m mebrofeninA diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests.
DB09138Technetium Tc-99m medronateA diagnostic radiopharmaceutical agent used as a bone imaging agent to delineate areas of altered osteogenesis.
DB09146Iron sucroseAn compound used as a source of iron in patients with iron deficiency anemia associated with chronic kidney disease (CKD).
DB09161Technetium Tc-99m sestamibiA radiopharmaceutical diagnostic agent used in nuclear medicine imaging tests to detect coronary artery disease and evaluate myocardial function.
DB09163Technetium Tc-99m exametazimeA radiopharmaceutical diagnostic agent used as an adjunct for scintigraphy in the detection of altered regional cerebral perfusion in stroke.
DB09164Technetium Tc-99m disofeninA radiopharmaceutical diagnostic agent used for hepatobiliary scans.
DB09276Sodium aurothiomalateA disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis.
DB09338MersalylElevated blood pressure, edema [L1577, L1585].
DB09501Ferric ammonium citrateNot Annotated
DB09507FerumoxsilNot Annotated
DB09508FerumoxidesNot Annotated
DB11171Ferric sulfateA medication used as a coagulant and hemostatic agent.
DB11210Ferrous bisglycinateFerrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and...
DB11417GleptoferronColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
DB11437NitarsoneNitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat...
DB11458RoxarsoneRoxarsone is an organoarsenic molecule added to poultry feed. The addition of this compound to poultry feed improves weight gain and feed efficiency as well as prevent the growth of...
DB11576Ferric oxideAn ingredient used in a number of skin protecting products.
DB11590ThimerosalUsed as preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes vaccines [L1671, L1672, L1673].
DB12208Iron isomaltoside 1000Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney...
DB12821PerflubutanePerflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable...
DB12864MelarsoprolMelarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis).
DB13049LobaplatinLobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, and Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma.
DB13145NedaplatinUsed in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers .
DB13257Ferrous sulfate anhydrousAn iron supplement used to prevent iron deficiency anemia.
DB13268AcetarsolAn anti infective used to treat a wide variety of infections in the body.
DB13381Sodium feredetateNot Annotated
DB13392MercurochromeMercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. It is an organomercuric disodium salt compound and a fluorescein that is available in many...
DB13423Ferric hydroxideNot Annotated
DB13569Ferrous chlorideNot Annotated
DB13763AurotioprolNot Annotated
DB13885Ferric subsulfateFerric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin...
DB13985Lutetium Lu 177 dotatateA radiolabeled somatostatin analog used to treat somatostatin receptor positive gastroenteropancreatic neuroendocrine tumors.
DB14026Thiosalicylic acidNot Annotated
DB14488Ferrous gluconateA medication used to treat iron-deficiency anemia.
DB14489Ferrous succinateUsed in preventing and treating iron-deficiency anemia.
DB14491Ferrous fumarateA medication used to treat iron-deficiency anemia.
DB14520Tetraferric tricitrate decahydrateA phosphate binder used to control serum phosphorus levels or as an iron supplement.
DB14695Ferric oxyhydroxideAn ingredient used to treat hyperphosphatemia in patients with renal failure or patients on dialysis.
DB02994Cacodylic acidNot Available
DB04456Arsenous acidNot Available
DB00364SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
DB14807Demplatin pegraglumerDemplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
DB09139Technetium Tc-99m oxidronateTechnetium Tc-99m oxidronate is indicated in adult and pediatric patients to be used in skeletal imaging for diagnosis of areas that can present altered osteogenesis. When administered intravenously, it is...
DB09160Technetium Tc-99m tetrofosminTechnetium-99m tetrofosmin is indicated for the diagnosis of heart abnormalities by exercise myocardial scintigraphy. The exercise myocardial scintigraphy is an established method for the diagnosis of the severity of coronary...
DB15536Ferric chlorideNot Annotated
DB01671p-Hydroxymercuribenzoic acidNot Available
DrugDrug NameTargetType
DB00113Technetium Tc-99m arcitumomabCarcinoembryonic antigen-related cell adhesion molecule 1target
DB00325NitroprussideAtrial natriuretic peptide receptor 1target
DB00325NitroprussideCytochrome P450 1A1enzyme
DB00526OxaliplatinDNAtarget
DB00526OxaliplatinSolute carrier family 22 member 2transporter
DB00526OxaliplatinHigh affinity copper uptake protein 1transporter
DB00526OxaliplatinSolute carrier family 22 member 3transporter
DB00526OxaliplatinATP-binding cassette sub-family G member 2transporter
DB00526OxaliplatinGlutathione S-transferase theta-1enzyme
DB00526OxaliplatinMetallothionein-1Aenzyme
DB00526OxaliplatinMetallothionein-2enzyme
DB00526OxaliplatinMyeloperoxidaseenzyme
DB00526OxaliplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00526OxaliplatinGlutathione S-transferase Penzyme
DB00526OxaliplatinGlutathione S-transferase Mu 1enzyme
DB00526OxaliplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00526OxaliplatinCanalicular multispecific organic anion transporter 1transporter
DB00526OxaliplatinCopper-transporting ATPase 2transporter
DB00526OxaliplatinCopper-transporting ATPase 1transporter
DB00534ChlormerodrinSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
DB00534ChlormerodrinSolute carrier family 12 member 1target
DB00789Gadopentetic acid6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00893Iron DextranHemoglobin subunit betatarget
DB00893Iron DextranHemoglobin subunit alphatarget
DB00893Iron DextranFerritin heavy chaintarget
DB00893Iron DextranFerritin light chaintarget
DB00893Iron DextranSerotransferrincarrier
DB00958CarboplatinDNAtarget
DB00958CarboplatinHigh affinity copper uptake protein 1transporter
DB00958CarboplatinProbable low affinity copper uptake protein 2transporter
DB00958CarboplatinXanthine dehydrogenase/oxidaseenzyme
DB00958CarboplatinMyeloperoxidaseenzyme
DB00958CarboplatinGlutathione S-transferase theta-1enzyme
DB00958CarboplatinMetallothionein-1Aenzyme
DB00958CarboplatinMetallothionein-2enzyme
DB00958CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00958CarboplatinGlutathione S-transferase Penzyme
DB00958CarboplatinGlutathione S-transferase Mu 1enzyme
DB00958CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00958CarboplatinCopper-transporting ATPase 1transporter
DB00958CarboplatinCopper-transporting ATPase 2transporter
DB00958CarboplatinATP-binding cassette sub-family G member 2transporter
DB00958CarboplatinCanalicular multispecific organic anion transporter 1transporter
DB00995AuranofinInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00995AuranofinSerum albumincarrier
DB00995AuranofinPeroxiredoxin-5, mitochondrialtarget
DB01169Arsenic trioxideInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB01169Arsenic trioxideTranscription factor AP-1target
DB01169Arsenic trioxideG1/S-specific cyclin-D1target
DB01169Arsenic trioxideMitogen-activated protein kinase 3target
DB01169Arsenic trioxideMitogen-activated protein kinase 1target
DB01169Arsenic trioxideRAC-alpha serine/threonine-protein kinasetarget
DB01169Arsenic trioxideCanalicular multispecific organic anion transporter 1transporter
DB01169Arsenic trioxideThioredoxin reductase 1, cytoplasmictarget
DB01169Arsenic trioxideP-glycoprotein 1transporter
DB01169Arsenic trioxideCytochrome P450 3A4enzyme
DB01169Arsenic trioxideCyclin-dependent kinase inhibitor 1target
DB01169Arsenic trioxideHistone deacetylase 1target
DB01169Arsenic trioxideProtein PMLtarget
DB01169Arsenic trioxideSerum albumincarrier
DB01592IronTransferrin receptor protein 1target
DB01592IronEgl nine homolog 1target
DB01592IronHistone deacetylase 8target
DB01592IronAlpha-hemoglobin-stabilizing proteintarget
DB01592IronHemoglobin subunit alphatarget
DB01592IronFrataxin, mitochondrialtarget
DB01592IronFerritin heavy chaintarget
DB01592IronFlap endonuclease 1target
DB01592IronEndonuclease 8-like 1target
DB01592IronEndonuclease 8-like 2target
DB01592IronDNA polymerase betatarget
DB01592IronCeruloplasmintarget
DB01592IronSerotransferrintarget
DB03006Arsanilic acidLysozyme Ctarget
DB04874PicoplatinDNAtarget
DB04992AP5346DNAtarget
DB04996SatraplatinDNAtarget
DB05488Technetium Tc-99m ciprofloxacinDNA gyrase subunit Btarget
DB05488Technetium Tc-99m ciprofloxacinDNA topoisomerase 2-betatarget
DB05488Technetium Tc-99m ciprofloxacinCytochrome P450 1A2enzyme
DB05630Sodium stibogluconateDNA topoisomerase 1target
DB06215FerumoxytolSerotransferrintransporter
DB06215FerumoxytolFerritin light chaintransporter
DB06215FerumoxytolFerritin heavy chaintransporter
DB08857Bamet-UD2Solute carrier organic anion transporter family member 1B1transporter
DB08858cis-Diamminechlorocholylglycinateplatinum(II)Solute carrier organic anion transporter family member 1B1transporter
DB08884Gadoxetic acidSolute carrier organic anion transporter family member 1B1transporter
DB08884Gadoxetic acidSolute carrier organic anion transporter family member 1B3transporter
DB08884Gadoxetic acidCanalicular multispecific organic anion transporter 2transporter
DB08884Gadoxetic acidCanalicular multispecific organic anion transporter 1transporter
DB08884Gadoxetic acidMultidrug resistance-associated protein 4transporter
DB09121AurothioglucoseAdenylate cyclase type 1target
DB09121AurothioglucoseAdenylate cyclase type 2target
DB09121AurothioglucoseAdenylate cyclase type 5target
DB09137Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B1transporter
DB09137Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B3transporter
DB09146Iron sucroseHemoglobin subunit alphatarget
DB09146Iron sucroseSerotransferrincarrier
DB09161Technetium Tc-99m sestamibiP-glycoprotein 1transporter
DB09161Technetium Tc-99m sestamibiMultidrug resistance-associated protein 1transporter
DB09276Sodium aurothiomalateUDP-glucuronosyltransferase 1-1enzyme
DB09338MersalylAlkaline phosphatase, tissue-nonspecific isozymetarget
DB09338MersalylAquaporin-1target
DB09338MersalylMonocarboxylate transporter 1target
DB09338MersalylInter-alpha-trypsin inhibitor heavy chain H1enzyme
DB09338MersalylPhosphoenolpyruvate carboxykinase, cytosolic [GTP]enzyme
DB11590ThimerosalSerum albumincarrier
DB11590ThimerosalInositol 1,4,5-trisphosphate receptor type 1transporter
DB11590ThimerosalMethionine synthasetarget
DB11590ThimerosalCystine/glutamate transportertarget
DB11590ThimerosalSodium/potassium-transporting ATPase subunit gammatarget
DB11590ThimerosalGlutathione reductase, mitochondrialenzyme
DB11590ThimerosalGlutathione peroxidase 1enzyme
DB11590ThimerosalSuperoxide dismutase [Mn], mitochondrialenzyme
DB13145NedaplatinGlutathionetarget
DB13145NedaplatinDNAtarget
DB13257Ferrous sulfate anhydrousSerotransferrintransporter
DB13257Ferrous sulfate anhydrousFerritin light chaintransporter
DB13257Ferrous sulfate anhydrousFerritin heavy chaintransporter
DB13257Ferrous sulfate anhydrousDivalent metal ion transporter 1transporter
DB13257Ferrous sulfate anhydrousIron binding protein FbpAtransporter
DB13257Ferrous sulfate anhydrousNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousXanthine dehydrogenase/oxidaseenzyme
DB13257Ferrous sulfate anhydrousAconitate hydratase, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousCytochrome P450 4A11enzyme
DB13257Ferrous sulfate anhydrousSulfite oxidase, mitochondrialenzyme
DB13257Ferrous sulfate anhydrousMyeloperoxidaseenzyme
DB13257Ferrous sulfate anhydrousCatalaseenzyme
DB13257Ferrous sulfate anhydrousNitric oxide synthase, inducibleenzyme
DB13257Ferrous sulfate anhydrousProstaglandin G/H synthase 1enzyme
DB13257Ferrous sulfate anhydrousProstaglandin G/H synthase 2enzyme
DB13257Ferrous sulfate anhydrousTryptophan 5-hydroxylase 1enzyme
DB13257Ferrous sulfate anhydrousProlyl 4-hydroxylase subunit alpha-1enzyme
DB13257Ferrous sulfate anhydrousPterin-4-alpha-carbinolamine dehydrataseenzyme
DB13257Ferrous sulfate anhydrousCeruloplasminenzyme
DB13257Ferrous sulfate anhydrousFree radicalstarget
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 2target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 1target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 3target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 4target
DB13985Lutetium Lu 177 dotatateSomatostatin receptor type 5target
DB14488Ferrous gluconateTransferrin receptor protein 1target
DB14488Ferrous gluconateEgl nine homolog 1target
DB14488Ferrous gluconateHistone deacetylase 8target
DB14488Ferrous gluconateAlpha-hemoglobin-stabilizing proteintarget
DB14488Ferrous gluconateHemoglobin subunit alphatarget
DB14488Ferrous gluconateFrataxin, mitochondrialtarget
DB14488Ferrous gluconateFerritin heavy chaintarget
DB14488Ferrous gluconateFlap endonuclease 1target
DB14488Ferrous gluconateEndonuclease 8-like 1target
DB14488Ferrous gluconateEndonuclease 8-like 2target
DB14488Ferrous gluconateDNA polymerase betatarget
DB14488Ferrous gluconateCeruloplasmintarget
DB14488Ferrous gluconateSerotransferrintarget
DB14489Ferrous succinateTransferrin receptor protein 1target
DB14489Ferrous succinateEgl nine homolog 1target
DB14489Ferrous succinateHistone deacetylase 8target
DB14489Ferrous succinateAlpha-hemoglobin-stabilizing proteintarget
DB14489Ferrous succinateHemoglobin subunit alphatarget
DB14489Ferrous succinateFrataxin, mitochondrialtarget
DB14489Ferrous succinateFerritin heavy chaintarget
DB14489Ferrous succinateFlap endonuclease 1target
DB14489Ferrous succinateEndonuclease 8-like 1target
DB14489Ferrous succinateEndonuclease 8-like 2target
DB14489Ferrous succinateDNA polymerase betatarget
DB14489Ferrous succinateCeruloplasmintarget
DB14489Ferrous succinateSerotransferrintarget
DB14491Ferrous fumarateTransferrin receptor protein 1target
DB14491Ferrous fumarateEgl nine homolog 1target
DB14491Ferrous fumarateHistone deacetylase 8target
DB14491Ferrous fumarateAlpha-hemoglobin-stabilizing proteintarget
DB14491Ferrous fumarateHemoglobin subunit alphatarget
DB14491Ferrous fumarateFrataxin, mitochondrialtarget
DB14491Ferrous fumarateFerritin heavy chaintarget
DB14491Ferrous fumarateFlap endonuclease 1target
DB14491Ferrous fumarateEndonuclease 8-like 1target
DB14491Ferrous fumarateEndonuclease 8-like 2target
DB14491Ferrous fumarateDNA polymerase betatarget
DB14491Ferrous fumarateCeruloplasmintarget
DB14491Ferrous fumarateSerotransferrintarget
DB14520Tetraferric tricitrate decahydrateSerotransferrincarrier
DB14520Tetraferric tricitrate decahydrateIron(3+)-hydroxamate-binding protein FhuDtarget
DB14520Tetraferric tricitrate decahydrateIntegrin beta-3carrier
DB14520Tetraferric tricitrate decahydrateCalreticulincarrier
DB14520Tetraferric tricitrate decahydrateTransferrin receptor protein 1target
DB02994Cacodylic acidGag-Pol polyproteintarget
DB02994Cacodylic acidNitric oxide synthase, endothelialtarget
DB02994Cacodylic acidAldose reductasetarget
DB02994Cacodylic acidGuanine nucleotide-binding protein G(t) subunit alpha-1target
DB04456Arsenous acidArsenate reductasetarget
DB04456Arsenous acidArsenical pump-driving ATPasetarget
DB00364SucralfateFibrinogentarget
DB00364SucralfatePepsin A-5target
DB00364SucralfatePro-epidermal growth factortarget
DB00364SucralfateFibroblast growth factor 2target
DB09139Technetium Tc-99m oxidronateSerum albumincarrier
DB09160Technetium Tc-99m tetrofosminP-glycoprotein 1carrier
DB01671p-Hydroxymercuribenzoic acidCarbonic anhydrase 2target