- Nitro Compounds
- Accession Number
Compounds having the nitro group, -NO2, attached to carbon. When attached to nitrogen they are nitramines and attached to oxygen they are NITRATES.
Drug Drug Description Tolcapone A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. Nitrofural For the treatment of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms. Chloramphenicol A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. Furazolidone For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms. Nitrofurantoin An antibiotic used to treat urinary tract infections. Nitroglycerin A nitrate vasodilator used to treat or prevent angina, treat hypertension, control heart failure in myocardial infarction, and to induce hypotension intraoperatively. Tinidazole A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Oxamniquine For treatment of Schistosomiasis caused by Schistosoma mansoni Nitroxoline Nitroxoline is an antibiotic agent. Picric acid Used as antiseptic, astringent, and stimulant for epitheliazation. 4-Nitrophenyl Phosphate Not Available P-Nitrophenol Not Available 2,4-Dinitrophenol A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman,... Pretomanid Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis. Evofosfamide Investigated for use/treatment in solid tumors. Bromamphenicol Not Available Chloramphenicol succinate A broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains. Thiamphenicol Not Available Efonidipine For the treatment of hypertension. Florfenicol Florfenicol is a fluorinated synthetic analog of thiamphenicol. Nifurpirinol Not Annotated Delamanid An antibiotic used to treat multidrug resistant tuberculosis. Misonidazole Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole). Nifurtimox Nifurtimox has been investigated for the treatment of Sleeping Sickness and Human African Trypanosomiasis. Dinitrochlorobenzene Dinitrochlorobenzene has been used in trials studying the treatment of HIV Infections. Benznidazole A trypanocidal agent used to treat Chagas disease. Nimorazole Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others. Fexinidazole Fexinidazole has been investigated for the treatment of Disease, Chagas and South American Trypanosomiasis. Pimonidazole Pimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer. Etanidazole Etanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others. Secnidazole A nitroimidazole antibiotic used to treat bacterial vaginosis. Ornidazole Ornidazole has been used in trials studying the prevention of Elective Colorectal Surgery. Nifurzide Not Annotated Azanidazole Not Annotated Furazidin Not Annotated Clefamide Not Annotated Nifuratel Not Annotated Nifurtoinol Not Annotated Nifuroxazide Not Annotated NS-398 NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. Chloramphenicol palmitate Not Annotated Morinidazole Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis). Fluoroazomycin arabinoside F-18 Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer). Azidamfenicol Not Annotated 1,3-Dinitrobenzene Not Available
- Drugs & Drug Targets