Sulfonic Acids

Inorganic or organic oxy acids of sulfur which contain the RSO2(OH) radical.
DrugDrug NameDrug Indication
DB00258Calcium acetateCalcium acetate is one of a number of calcium salts used to treat hyperphosphatemia (too much phosphate in the blood) in patients with kidney disease.
DB00464Sodium Tetradecyl SulfateFor the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves.
DB00659AcamprosateFor the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation
DB00815Sodium lauryl sulfateSLS is used as a surfactant in shampoos and toothpastes. SLS also has microbicidal activities against both enveloped (Herpes simplex viruses, HIV-1, Semliki Forest virus) and nonenveloped (papillomaviruses, reovirus, rotavirus and poliovirus) viruses, although it has not been approved for this use.
DB01008BusulfanFor use in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous (myeloid, myelocytic, granulocytic) leukemia (FDA has designated busulfan as an orphan drug for this use). It is also used as a component of pretransplant conditioning regimens in patients undergoing bone marrow transplantation for acute myeloid leukemia and nonmalignant diseases.
DB03120Para-Toluene SulfonateNot Available
DB031323-(2-Benzothiazolylthio)-1-Propanesulfonic AcidNot Available
DB03309N-CyclohexyltaurineNot Available
DB03635Ethanesulfonic AcidNot Available
DB03656Tribenuron MethylNot Available
DB03967Dodecyl sulfateNot Available
DB04348Taurocholic AcidNot Available
DB04640Naphthalene-2,6-disulfonic acidNot Available
DB04786SuraminFor treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
DB05377ChlorfensonInvestigated for use/treatment in fungal infections.
DB05385PRO 2000Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection.
DB06231CaldaretInvestigated for use/treatment in heart disease and myocardial infarction.
DB06527TramiprosateInvestigated for use/treatment in strokes and alzheimer's disease.
DB06536TesaglitazarInvestigated for use/treatment in diabetes mellitus type 2.
DB082542-NAPHTHALENESULFONIC ACIDNot Available
DB08834Tauroursodeoxycholic acidUsed in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis.
DB09110Coenzyme MMesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis. (2)
DB09158Trypan blue free acidTrypan blue is indicated for use as an aid in ophthalmic surgery by staining the epiretinal membranes during ophthalmic surgical vitrectomy procedures, facilitating removal of the tissue.
DB11183Light green SF yellowishNot Available
DB11678TreosulfanNot Available
DB12197AuricloseneNot Available
DB12473TaurolidineNot Available
DB13529Dobesilic acidNot Available
DrugDrug NameTargetType
DB00258Calcium acetatePhosphatetarget
DB00464Sodium Tetradecyl SulfateVitamin K-dependent protein Ctarget
DB00464Sodium Tetradecyl SulfateVitamin K-dependent protein Starget
DB00659AcamprosateMetabotropic glutamate receptor 5target
DB00659AcamprosateGABA-A receptor (anion channel)target
DB00659AcamprosateGlutamate (NMDA) receptortarget
DB00659AcamprosateProton-coupled amino acid transporter 1transporter
DB00815Sodium lauryl sulfateSerum albumincarrier
DB01008BusulfanCytochrome P450 3A4enzyme
DB01008BusulfanGlutathione S-transferase A2enzyme
DB01008BusulfanGlutathione S-transferase A1enzyme
DB01008BusulfanGlutathione S-transferase Mu 1enzyme
DB01008BusulfanGlutathione S-transferase Penzyme
DB01008BusulfanMicrosomal glutathione S-transferase 2enzyme
DB01008BusulfanDNAtarget
DB03120Para-Toluene SulfonateLysozyme Ctarget
DB03120Para-Toluene SulfonatePro-cathepsin Htarget
DB031323-(2-Benzothiazolylthio)-1-Propanesulfonic AcidTriosephosphate isomerase, glycosomaltarget
DB031323-(2-Benzothiazolylthio)-1-Propanesulfonic AcidTriosephosphate isomerasetarget
DB03309N-CyclohexyltaurineSulfotransferase family cytosolic 2B member 1target
DB03309N-CyclohexyltaurineNitrite reductasetarget
DB03309N-CyclohexyltaurineHomeobox protein engrailed-2target
DB03309N-CyclohexyltaurineRibonuclease PHtarget
DB03309N-CyclohexyltaurineCyanovirin-Ntarget
DB03309N-CyclohexyltaurinePhosphoproteintarget
DB03635Ethanesulfonic AcidPlatelet basic proteintarget
DB03635Ethanesulfonic AcidPhosphonoacetaldehyde hydrolasetarget
DB03967Dodecyl sulfateLysozyme Ctarget
DB03967Dodecyl sulfateLipid A palmitoyltransferase PagPtarget
DB04348Taurocholic AcidBile salt-activated lipasetarget
DB04348Taurocholic AcidGastrotropintarget
DB04348Taurocholic AcidBile acid receptortarget
DB04348Taurocholic AcidBile salt export pumptransporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1A2transporter
DB04348Taurocholic AcidIleal sodium/bile acid cotransportertransporter
DB04348Taurocholic AcidCanalicular multispecific organic anion transporter 1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1B1transporter
DB04348Taurocholic AcidSolute carrier family 22 member 1transporter
DB04348Taurocholic AcidCanalicular multispecific organic anion transporter 2transporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 4transporter
DB04348Taurocholic AcidMultidrug resistance protein 1transporter
DB04348Taurocholic AcidSolute carrier family 22 member 6transporter
DB04348Taurocholic AcidMultidrug resistance-associated protein 7transporter
DB04348Taurocholic AcidSolute carrier family 22 member 8transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 4A1transporter
DB04348Taurocholic AcidATP-binding cassette sub-family C member 11transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1C1transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 3A1transporter
DB04348Taurocholic AcidATP-binding cassette sub-family G member 2transporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 2B1transporter
DB04348Taurocholic AcidMonocarboxylate transporter 1transporter
DB04348Taurocholic AcidSodium/bile acid cotransportertransporter
DB04348Taurocholic AcidOrganic solute transporter subunit alphatransporter
DB04348Taurocholic AcidOrganic solute transporter subunit betatransporter
DB04348Taurocholic AcidSolute carrier organic anion transporter family member 1B3transporter
DB04348Taurocholic AcidCystine/glutamate transportertransporter
DB04640Naphthalene-2,6-disulfonic acidL-lactate dehydrogenasetarget
DB04640Naphthalene-2,6-disulfonic acidBacterioferritin comigratory proteintarget
DB04786SuraminArylsulfatase Aenzyme
DB04786SuraminCytosolic phospholipase A2enzyme
DB04786SuraminNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
DB04786SuraminComplement control protein C3target
DB04786SuraminPhospholipase A2, membrane associatedtarget
DB04786SuraminProthrombintarget
DB04786SuraminP2Y purinoceptor 2target
DB04786SuraminFollicle-stimulating hormone receptortarget
DB04786SuraminRyanodine receptor 1target
DB06231CaldaretSodium/calcium exchanger 1target
DB06536TesaglitazarPeroxisome proliferator-activated receptor alphatarget
DB06536TesaglitazarPeroxisome proliferator-activated receptor gammatarget
DB082542-NAPHTHALENESULFONIC ACIDProthrombintarget
DB082542-NAPHTHALENESULFONIC ACIDTrypsin-1target
DB08834Tauroursodeoxycholic acidCytochrome P450 3A1enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 3A2enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2A1enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2A2enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2B1enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2B2enzyme
DB08834Tauroursodeoxycholic acidCytochrome P450 2B9enzyme
DB08834Tauroursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
DB08834Tauroursodeoxycholic acidCystine/glutamate transportertransporter
DB09110Coenzyme MGlutathione reductase, mitochondrialenzyme