Cytochrome P-450 CYP1A2 Inducers (strong)

DrugDrug NameDrug Description
DB01045RifampicinAn antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
DB00564CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
DB00794PrimidoneAn antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
DB00518AlbendazoleA benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections.
DrugDrug NameTargetType
DB01045RifampicinDNA-directed RNA polymerase subunit betatarget
DB01045RifampicinNuclear receptor subfamily 1 group I member 2target
DB01045RifampicinCytochrome P450 3A4enzyme
DB01045RifampicinCytochrome P450 1A2enzyme
DB01045RifampicinCytochrome P450 2C8enzyme
DB01045RifampicinUDP-glucuronosyltransferase 1-1enzyme
DB01045RifampicinCytochrome P450 2C9enzyme
DB01045RifampicinCytochrome P450 2B6enzyme
DB01045RifampicinCytochrome P450 2C19enzyme
DB01045RifampicinCanalicular multispecific organic anion transporter 2transporter
DB01045RifampicinMultidrug resistance-associated protein 5transporter
DB01045RifampicinP-glycoprotein 1transporter
DB01045RifampicinCanalicular multispecific organic anion transporter 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 2B1transporter
DB01045RifampicinBile salt export pumptransporter
DB01045RifampicinMultidrug resistance-associated protein 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1A2transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B3transporter
DB01045RifampicinSolute carrier family 22 member 7transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B1transporter
DB01045RifampicinCytochrome P450 2A6enzyme
DB01045RifampicinCytochrome P450 2E1enzyme
DB01045RifampicinCytochrome P450 3A43enzyme
DB01045RifampicinCytochrome P450 3A7enzyme
DB01045RifampicinSolute carrier family 22 member 6transporter
DB01045RifampicinSolute carrier family 22 member 8transporter
DB01045RifampicinUDP-glucuronosyltransferase 1-9enzyme
DB01045RifampicinCytochrome P450 3A5enzyme
DB01045RifampicinSerum albumincarrier
DB01045Rifampicinalpha1-acid glycoproteincarrier
DB00564CarbamazepineVoltage-gated sodium channel alpha subunittarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineP-glycoprotein 1transporter
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
DB00794PrimidoneCytochrome P450 2C19enzyme
DB00794PrimidoneCytochrome P450 2C9enzyme
DB00794PrimidoneCytochrome P450 3A4enzyme
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
DB00794PrimidoneGlutamate receptor 2target
DB00794PrimidoneGlutamate receptor ionotropic, kainate 2target
DB00794PrimidoneGABA-A receptor (anion channel)target
DB00794PrimidoneTransient receptor potential cation channel subfamily M member 3transporter
DB00794PrimidoneCytochrome P450 2E1enzyme
DB00794PrimidoneCytochrome P450 1A2enzyme
DB00794PrimidoneUDP-glucuronosyltransferases (UGTs)enzyme
DB00518AlbendazoleTubulin alpha-1A chaintarget
DB00518AlbendazoleTubulin beta-4B chaintarget
DB00518AlbendazoleCytochrome P450 3A4enzyme
DB00518AlbendazoleFumarate reductase flavoprotein subunittarget
DB00518AlbendazoleCytochrome P450 1A1enzyme
DB00518AlbendazoleCytochrome P450 1A2enzyme
DB00518AlbendazoleTubulin beta-2 chaintarget
DB00518AlbendazoleCytochrome P450 2C19enzyme