OAT1/SLC22A6 Substrates

DrugDrug NameDrug Description
DB00345Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
DB03553Glutaric AcidNot Available
DB00369CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
DB00718Adefovir dipivoxilA nucleotide analog used to treat chronic hepatitis B.
DB00501CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
DB00787AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
DB09299Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
DB00300Tenofovir disoproxilA nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
DB00917DinoprostoneA prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.
DB01327CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
DB00567CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
DB04348Taurocholic acidThe product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats...
DB02527Cyclic adenosine monophosphateCyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
DB00709LamivudineA reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
DB01137LevofloxacinA fluoroquinolone used to treat infections including the upper respiratory tract, skin and skin structure, urinary tract, as well as pneumonia, chronic bacterial prostatitis, post exposure treatment of inhaled anthrax, and the plague.
DB00365GrepafloxacinA fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
DB00649StavudineA dideoxynucleoside used in the treatment of HIV infection.
DB00943ZalcitabineA dideoxynucleoside used to treat HIV.
DB00900DidanosineA reverse transcriptase inhibitor used to treat HIV.
DB01414CefacetrileCefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.
DB01197CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
DB00535CefdinirA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
DB00229CefotiamFor treatment of severe infections caused by susceptible bacteria.
DB01415CeftibutenA third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
DB01332CeftizoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.
DB09008CefaloridineCephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
DB00155CitrullineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
DB12243EdaravoneA free radical scavenger used to delay the progression of ALS.
DB08846Ellagic acidEllagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines.
DB00693FluoresceinA dye used in angiography or angioscopy of the iris and retina.
DB00328IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
DB00770AlprostadilA medication used to treat erectile dysfunction.
DB00863RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
DB09298SilibininCurrently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
DB00432TrifluridineA nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
DB00495ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
DB01606TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DrugDrug NameTargetType
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB03553Glutaric AcidAspartate aminotransferasetarget
DB03553Glutaric AcidBranched-chain-amino-acid aminotransferasetarget
DB03553Glutaric AcidGlutamate decarboxylase alphatarget
DB03553Glutaric AcidSolute carrier family 22 member 6transporter
DB03553Glutaric AcidSolute carrier family 22 member 8transporter
DB03553Glutaric AcidSolute carrier family 22 member 11transporter
DB03553Glutaric AcidSolute carrier family 22 member 7transporter
DB00369CidofovirDNA polymerase catalytic subunittarget
DB00369CidofovirSolute carrier family 22 member 6transporter
DB00369CidofovirThymidine phosphorylaseenzyme
DB00718Adefovir dipivoxilDNA polymerase/reverse transcriptasetarget
DB00718Adefovir dipivoxilSolute carrier family 22 member 6transporter
DB00718Adefovir dipivoxilMultidrug resistance-associated protein 4transporter
DB00718Adefovir dipivoxilMultidrug resistance-associated protein 5transporter
DB00718Adefovir dipivoxilSolute carrier family 22 member 3transporter
DB00718Adefovir dipivoxilAdenylate kinase 2, mitochondrialenzyme
DB00718Adefovir dipivoxilAdenylate kinase 4, mitochondrialenzyme
DB00718Adefovir dipivoxilNucleoside diphosphate kinase Aenzyme
DB00718Adefovir dipivoxilNucleoside diphosphate kinase Benzyme
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineP-glycoprotein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineMultidrug and toxin extrusion protein 2transporter
DB00787AcyclovirDNA polymerase catalytic subunittarget
DB00787AcyclovirDNA polymerase catalytic subunittarget
DB00787AcyclovirThymidine kinasetarget
DB00787AcyclovirSolute carrier family 22 member 1transporter
DB00787AcyclovirSolute carrier family 22 member 6transporter
DB00787AcyclovirSolute carrier family 22 member 8transporter
DB00787AcyclovirIleal sodium/bile acid cotransportertransporter
DB00787AcyclovirMultidrug and toxin extrusion protein 1transporter
DB00787AcyclovirMultidrug and toxin extrusion protein 2transporter
DB00787AcyclovirThymidine kinaseenzyme
DB00787AcyclovirGuanylate kinaseenzyme
DB00787AcyclovirNucleoside diphosphokinaseenzyme
DB00787AcyclovirPyruvate Kinasesenzyme
DB00787AcyclovirCreatine Kinasesenzyme
DB00787AcyclovirPhosphoglycerate Kinasesenzyme
DB00787AcyclovirSuccinyl-CoA Synthetasesenzyme
DB00787AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
DB00787AcyclovirAdenylosuccinate Synthetasesenzyme
DB00787AcyclovirSerum albumincarrier
DB09299Tenofovir alafenamideReverse transcriptase/RNaseHtarget
DB09299Tenofovir alafenamideP-glycoprotein 1transporter
DB09299Tenofovir alafenamideMultidrug resistance-associated protein 4transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 6transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 8transporter
DB09299Tenofovir alafenamideLysosomal protective proteinenzyme
DB09299Tenofovir alafenamideLiver carboxylesterase 1enzyme
DB09299Tenofovir alafenamideATP-binding cassette sub-family G member 2transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B1transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B3transporter
DB09299Tenofovir alafenamideReverse transcriptasetarget
DB09299Tenofovir alafenamideDNA polymerasetarget
DB09299Tenofovir alafenamideSerum albumincarrier
DB09299Tenofovir alafenamideCytochrome P450 3A4enzyme
DB09299Tenofovir alafenamideAdenylate kinase isoenzyme 1enzyme
DB09299Tenofovir alafenamideAdenylate kinase 2, mitochondrialenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Aenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Benzyme
DB00300Tenofovir disoproxilReverse transcriptase/RNaseHtarget
DB00300Tenofovir disoproxilSolute carrier family 22 member 6transporter
DB00300Tenofovir disoproxilSolute carrier family 22 member 8transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 7transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 4transporter
DB00300Tenofovir disoproxilCanalicular multispecific organic anion transporter 1transporter
DB00300Tenofovir disoproxilAdenylate kinase 2, mitochondrialenzyme
DB00300Tenofovir disoproxilAdenylate kinase 4, mitochondrialenzyme
DB00300Tenofovir disoproxilP-glycoprotein 1transporter
DB00300Tenofovir disoproxilNucleoside diphosphokinaseenzyme
DB00300Tenofovir disoproxilCreatine Kinasesenzyme
DB00300Tenofovir disoproxilDNA polymerase/reverse transcriptasetarget
DB00917DinoprostoneProstaglandin E2 receptor EP2 subtypetarget
DB00917DinoprostoneProstaglandin E2 receptor EP1 subtypetarget
DB00917DinoprostoneProstaglandin E2 receptor EP4 subtypetarget
DB00917DinoprostoneProstaglandin E2 receptor EP3 subtypetarget
DB00917DinoprostoneSolute carrier family 22 member 2transporter
DB00917DinoprostoneMultidrug resistance-associated protein 5transporter
DB00917DinoprostoneSolute carrier family 22 member 6transporter
DB00917DinoprostoneSolute carrier family 22 member 8transporter
DB00917DinoprostoneSolute carrier family 22 member 11transporter
DB00917DinoprostoneSolute carrier family 22 member 7transporter
DB00917DinoprostoneMultidrug resistance-associated protein 4transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 2B1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 1A2transporter
DB00917DinoprostoneOrganic solute transporter subunit alphatransporter
DB00917DinoprostoneOrganic solute transporter subunit betatransporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 2A1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 4A1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 1C1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 3A1transporter
DB00917DinoprostoneSolute carrier organic anion transporter family member 1B1transporter
DB00917DinoprostoneProstaglandin D2 receptor 2target
DB01327CefazolinSerum paraoxonase/arylesterase 1target
DB01327CefazolinSerum albumincarrier
DB01327CefazolinSolute carrier family 22 member 6transporter
DB01327CefazolinSolute carrier family 22 member 8transporter
DB01327CefazolinSolute carrier family 22 member 11transporter
DB01327CefazolinPenicillin-binding protein 1Atarget
DB01327CefazolinPenicillin-binding protein 1Btarget
DB01327CefazolinPenicillin-binding protein 2target
DB01327CefazolinPenicillin-binding protein 1Ctarget
DB01327CefazolinPeptidoglycan synthase FtsItarget
DB01327CefazolinMultidrug resistance-associated protein 4transporter
DB01327CefazolinThiopurine S-methyltransferaseenzyme
DB01327CefazolinInterleukin-15target
DB01327CefazolinInterleukin-2target
DB00567CephalexinSerum albumincarrier
DB00567CephalexinSolute carrier family 22 member 5transporter
DB00567CephalexinSolute carrier family 15 member 1transporter
DB00567CephalexinSolute carrier family 15 member 2transporter
DB00567CephalexinSolute carrier family 22 member 6transporter
DB00567CephalexinSolute carrier family 22 member 8transporter
DB00567CephalexinMultidrug and toxin extrusion protein 1transporter
DB00567CephalexinPenicillin-binding protein 3target
DB00567CephalexinPenicillin-binding protein 2atarget
DB00567CephalexinPenicillin-binding protein 1btarget
DB00567CephalexinPenicillin-binding protein 1Atarget
DB00567CephalexinPenicillin-binding protein 2Btarget
DB04348Taurocholic acidBile salt-activated lipasetarget
DB04348Taurocholic acidGastrotropintarget
DB04348Taurocholic acidBile salt export pumptransporter
DB04348Taurocholic acidMultidrug resistance-associated protein 1transporter
DB04348Taurocholic acidSolute carrier organic anion transporter family member 1A2transporter
DB04348Taurocholic acidIleal sodium/bile acid cotransportertransporter
DB04348Taurocholic acidCanalicular multispecific organic anion transporter 1transporter
DB04348Taurocholic acidSolute carrier organic anion transporter family member 1B1transporter
DB04348Taurocholic acidCanalicular multispecific organic anion transporter 2transporter
DB04348Taurocholic acidMultidrug resistance-associated protein 4transporter
DB04348Taurocholic acidP-glycoprotein 1transporter
DB04348Taurocholic acidSolute carrier family 22 member 6transporter
DB04348Taurocholic acidMultidrug resistance-associated protein 7transporter
DB04348Taurocholic acidSolute carrier family 22 member 8transporter
DB04348Taurocholic acidSolute carrier organic anion transporter family member 4A1transporter
DB04348Taurocholic acidATP-binding cassette sub-family C member 11transporter
DB04348Taurocholic acidSolute carrier organic anion transporter family member 1C1transporter
DB04348Taurocholic acidSolute carrier organic anion transporter family member 3A1transporter
DB04348Taurocholic acidATP-binding cassette sub-family G member 2transporter
DB04348Taurocholic acidSolute carrier organic anion transporter family member 2B1transporter
DB04348Taurocholic acidMonocarboxylate transporter 1transporter
DB04348Taurocholic acidSodium/bile acid cotransportertransporter
DB04348Taurocholic acidOrganic solute transporter subunit alphatransporter
DB04348Taurocholic acidOrganic solute transporter subunit betatransporter
DB04348Taurocholic acidSolute carrier organic anion transporter family member 1B3transporter
DB04348Taurocholic acidCystine/glutamate transportertransporter
DB04348Taurocholic acidBile acid receptortarget
DB02527Cyclic adenosine monophosphatePotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2target
DB02527Cyclic adenosine monophosphatecAMP-dependent protein kinase type I-alpha regulatory subunittarget
DB02527Cyclic adenosine monophosphatecAMP-dependent protein kinase type II-beta regulatory subunittarget
DB02527Cyclic adenosine monophosphatecAMP-activated global transcriptional regulator CRPtarget
DB02527Cyclic adenosine monophosphateAdenylate cyclasetarget
DB02527Cyclic adenosine monophosphateCyclic nucleotide-gated potassium channel mll3241target
DB02527Cyclic adenosine monophosphateMultidrug resistance-associated protein 4transporter
DB02527Cyclic adenosine monophosphateMultidrug resistance-associated protein 5transporter
DB02527Cyclic adenosine monophosphateATP-binding cassette sub-family C member 11transporter
DB02527Cyclic adenosine monophosphateSolute carrier family 22 member 6transporter
DB02527Cyclic adenosine monophosphateSolute carrier family 22 member 8transporter
DB02527Cyclic adenosine monophosphateSolute carrier family 22 member 7transporter
DB00709LamivudineDNAtarget
DB00709LamivudineProtein Ptarget
DB00709LamivudineMultidrug resistance-associated protein 1transporter
DB00709LamivudineSolute carrier family 22 member 6transporter
DB00709LamivudineATP-binding cassette sub-family G member 2transporter
DB00709LamivudineReverse transcriptase/RNaseHtarget
DB00709LamivudineSolute carrier family 22 member 1transporter
DB00709LamivudineSolute carrier family 22 member 2transporter
DB00709LamivudineSolute carrier family 22 member 3transporter
DB00709LamivudineDeoxycytidine kinaseenzyme
DB00709LamivudineUMP-CMP kinaseenzyme
DB00709LamivudinePhosphoglycerate kinase 1enzyme
DB00709LamivudineNucleoside diphosphate kinase Aenzyme
DB00709LamivudineNucleoside diphosphate kinase Benzyme
DB00709LamivudineCholine-phosphate cytidylyltransferase Aenzyme
DB00709LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
DB00709LamivudineP-glycoprotein 1transporter
DB00709LamivudineMultidrug resistance-associated protein 4transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 2transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 1transporter
DB00709Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
DB00709LamivudineSerum albumincarrier
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinP-glycoprotein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB01137LevofloxacinMultidrug and toxin extrusion protein 1transporter
DB01137LevofloxacinMultidrug and toxin extrusion protein 2transporter
DB01137LevofloxacinCytochrome P450 2C9enzyme
DB00365GrepafloxacinDNA gyrase subunit Atarget
DB00365GrepafloxacinDNA topoisomerase 4 subunit Atarget
DB00365GrepafloxacinCytochrome P450 3A4enzyme
DB00365GrepafloxacinCytochrome P450 1A2enzyme
DB00365GrepafloxacinSolute carrier family 22 member 2transporter
DB00365GrepafloxacinSolute carrier family 22 member 5transporter
DB00365GrepafloxacinCanalicular multispecific organic anion transporter 1transporter
DB00365GrepafloxacinP-glycoprotein 1transporter
DB00365GrepafloxacinMultidrug resistance-associated protein 1transporter
DB00365GrepafloxacinSolute carrier family 22 member 6transporter
DB00649StavudineSolute carrier family 22 member 6transporter
DB00649StavudineReverse transcriptase/RNaseHtarget
DB00649StavudineSodium/nucleoside cotransporter 1transporter
DB00649StavudineSerum albumincarrier
DB00943ZalcitabineDeoxycytidine kinaseenzyme
DB00943ZalcitabineSolute carrier family 22 member 6transporter
DB00943ZalcitabineSolute carrier family 22 member 7transporter
DB00943ZalcitabineReverse transcriptase/RNaseHtarget
DB00943ZalcitabineEquilibrative nucleoside transporter 1transporter
DB00943ZalcitabineEquilibrative nucleoside transporter 2transporter
DB00943ZalcitabineSerum albumincarrier
DB00900DidanosineSolute carrier family 22 member 6transporter
DB00900DidanosinePurine nucleoside phosphorylasetarget
DB00900DidanosineReverse transcriptase/RNaseHtarget
DB00900DidanosineEquilibrative nucleoside transporter 1transporter
DB00900DidanosineEquilibrative nucleoside transporter 2transporter
DB00900DidanosineSerum albumincarrier
DB01414CefacetrilePenicillin-binding protein 1Atarget
DB01414CefacetrilePenicillin-binding protein 1Btarget
DB01414CefacetrileSolute carrier family 22 member 6transporter
DB01414CefacetrileSolute carrier family 22 member 8transporter
DB01197CaptoprilAngiotensin-converting enzymetarget
DB01197CaptoprilSerum albumincarrier
DB01197Captopril72 kDa type IV collagenasetarget
DB01197CaptoprilMatrix metalloproteinase-9target
DB01197CaptoprilP-glycoprotein 1transporter
DB01197CaptoprilSolute carrier family 15 member 1transporter
DB01197CaptoprilSolute carrier family 22 member 6transporter
DB01197CaptoprilLeukotriene A-4 hydrolasetarget
DB01197CaptoprilB1 bradykinin receptortarget
DB00535CefdinirMyeloperoxidasetarget
DB00535CefdinirPenicillin-binding protein 2target
DB00535CefdinirPBP3target
DB00535CefdinirSolute carrier family 22 member 5transporter
DB00535CefdinirSolute carrier family 15 member 1transporter
DB00535CefdinirSolute carrier family 15 member 2transporter
DB00535CefdinirSolute carrier family 22 member 6transporter
DB00535CefdinirSolute carrier family 22 member 8transporter
DB00535CefdinirPeptidoglycan transpeptidasetarget
DB00229CefotiamPenicillin-binding protein 1Atarget
DB00229CefotiamSolute carrier family 22 member 6transporter
DB00229CefotiamSolute carrier family 22 member 8transporter
DB01415CeftibutenSolute carrier family 15 member 1transporter
DB01415CeftibutenSolute carrier family 15 member 2transporter
DB01415CeftibutenPeptidoglycan synthase FtsItarget
DB01415CeftibutenPenicillin-binding protein 1Atarget
DB01415CeftibutenPenicillin-binding protein 1Btarget
DB01415CeftibutenPenicillin-binding protein 2target
DB01415CeftibutenSolute carrier family 22 member 6transporter
DB01415CeftibutenSolute carrier family 22 member 8transporter
DB01332CeftizoximeSolute carrier family 15 member 1transporter
DB01332CeftizoximePeptidoglycan synthase FtsItarget
DB01332CeftizoximePenicillin-binding protein 1Atarget
DB01332CeftizoximePenicillin-binding protein 1Btarget
DB01332CeftizoximeMecA PBP2' (penicillin binding protein 2')target
DB01332CeftizoximeSolute carrier family 22 member 6transporter
DB01332CeftizoximeSolute carrier family 22 member 8transporter
DB09008CefaloridineSolute carrier family 22 member 6transporter
DB09008CefaloridineSolute carrier family 22 member 8transporter
DB00155CitrullineNitric oxide synthase, endothelialtarget
DB00155CitrullineArgininosuccinate synthasetarget
DB00155CitrullineN(G),N(G)-dimethylarginine dimethylaminohydrolase 2target
DB00155CitrullineArgininosuccinate synthetase, isoform CRA_atarget
DB00155CitrullineN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00155CitrullineOrnithine carbamoyltransferase, mitochondrialtarget
DB00155CitrullineNitric oxide synthase, braintarget
DB00155CitrullineNitric oxide synthase, inducibletarget
DB00155CitrullineProtein-arginine deiminase type-4target
DB00155CitrullineProtein-arginine deiminase type-6target
DB00155CitrullineProtein-arginine deiminase type-1target
DB00155CitrullineProtein-arginine deiminase type-3target
DB00155CitrullineProtein-arginine deiminase type-2target
DB00155CitrullineSolute carrier family 22 member 6transporter
DB12243EdaravoneSolute carrier family 22 member 6transporter
DB12243EdaravoneSolute carrier family 22 member 8transporter
DB08846Ellagic acidSolute carrier family 22 member 6transporter
DB08846Ellagic acidSolute carrier family 22 member 11transporter
DB08846Ellagic acidCytochrome P450 1A1enzyme
DB08846Ellagic acidCytochrome P450 2E1enzyme
DB08846Ellagic acidCarbonic anhydrase 1target
DB08846Ellagic acidCarbonic anhydrase 2target
DB08846Ellagic acidCarbonic anhydrase 3target
DB08846Ellagic acidCarbonic anhydrase 4target
DB08846Ellagic acidCarbonic anhydrase 5A, mitochondrialtarget
DB08846Ellagic acidCarbonic anhydrase 5B, mitochondrialtarget
DB08846Ellagic acidCarbonic anhydrase 6target
DB08846Ellagic acidCarbonic anhydrase 7target
DB08846Ellagic acidCarbonic anhydrase 9target
DB08846Ellagic acidCarbonic anhydrase 12target
DB08846Ellagic acidCarbonic anhydrase 14target
DB08846Ellagic acidCasein kinase II subunit alphatarget
DB08846Ellagic acidcAMP-dependent protein kinase catalytic subunit alphatarget
DB08846Ellagic acidProtein kinase C alpha typetarget
DB08846Ellagic acidProtein kinase C beta typetarget
DB08846Ellagic acidTyrosine-protein kinase SYKtarget
DB08846Ellagic acidSqualene monooxygenasetarget
DB00693FluoresceinIg kappa chain V-II region RPMI 6410target
DB00693FluoresceinDNAtarget
DB00693FluoresceinSolute carrier family 22 member 6transporter
DB00693FluoresceinBile salt export pumptransporter
DB00693FluoresceinMultidrug resistance-associated protein 1transporter
DB00328IndomethacinProstaglandin G/H synthase 1target
DB00328IndomethacinProstaglandin G/H synthase 2target
DB00328IndomethacinCytochrome P450 2C19enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndomethacinPhospholipase A2, membrane associatedtarget
DB00328IndomethacinProstaglandin reductase 2target
DB00328IndomethacinLactoylglutathione lyasetarget
DB00328IndomethacinProstaglandin D2 receptor 2target
DB00328IndomethacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndomethacinSerum albumincarrier
DB00328IndomethacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndomethacinMultidrug resistance-associated protein 4transporter
DB00328IndomethacinMultidrug resistance-associated protein 6transporter
DB00328IndomethacinP-glycoprotein 1transporter
DB00328IndomethacinMultidrug resistance-associated protein 1transporter
DB00328IndomethacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndomethacinSolute carrier family 22 member 6transporter
DB00328IndomethacinSolute carrier family 22 member 8transporter
DB00328IndomethacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndomethacinATP-binding cassette sub-family C member 11transporter
DB00328IndomethacinSolute carrier family 22 member 11transporter
DB00328IndomethacinSodium/bile acid cotransportertransporter
DB00328IndomethacinSolute carrier family 22 member 7transporter
DB00328IndomethacinCytochrome P450 2C9enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndomethacinLiver carboxylesterase 1enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndomethacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndomethacinAldo-keto reductase family 1 member C3target
DB00328IndomethacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndomethacinBile salt export pumptransporter
DB00770AlprostadilProstaglandin E2 receptor EP2 subtypetarget
DB00770AlprostadilProstaglandin E2 receptor EP1 subtypetarget
DB00770AlprostadilMultidrug resistance-associated protein 5transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2B1transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 3A1transporter
DB00770AlprostadilMultidrug resistance-associated protein 4transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2A1transporter
DB00770AlprostadilProstaglandin D2 receptor 2target
DB00770AlprostadilSolute carrier family 22 member 6transporter
DB00863RanitidineHistamine H2 receptortarget
DB00863RanitidineCytochrome P450 1A2enzyme
DB00863RanitidineCytochrome P450 2D6enzyme
DB00863RanitidineSolute carrier family 22 member 1transporter
DB00863RanitidineP-glycoprotein 1transporter
DB00863RanitidineSolute carrier family 22 member 8transporter
DB00863RanitidineCytochrome P450 3A4enzyme
DB00863RanitidineAcetylcholinesterasetarget
DB00863RanitidineSolute carrier family 22 member 2transporter
DB00863RanitidineAcetylcholinesteraseenzyme
DB09298SilibininSolute carrier family 22 member 6transporter
DB09298SilibininUDP-glucuronosyltransferase 1-1enzyme
DB09298SilibininSolute carrier organic anion transporter family member 1B1transporter
DB09298SilibininSolute carrier organic anion transporter family member 1B3transporter
DB09298SilibininSolute carrier organic anion transporter family member 2B1transporter
DB00432TrifluridineThymidylate synthasetarget
DB00432TrifluridineDNAtarget
DB00432TrifluridineThymidine kinase, cytosolicenzyme
DB00432TrifluridineThymidine phosphorylaseenzyme
DB00432TrifluridineSolute carrier family 22 member 6transporter
DB00432TrifluridineSodium/nucleoside cotransporter 1transporter
DB00432TrifluridineEquilibrative nucleoside transporter 1transporter
DB00432TrifluridineEquilibrative nucleoside transporter 2transporter
DB00432TrifluridineSerum albumincarrier
DB00495ZidovudineSerum albumincarrier
DB00495ZidovudineCytochrome P450 2A6enzyme
DB00495ZidovudineCytochrome P450 2C9enzyme
DB00495ZidovudineCytochrome P450 3A4enzyme
DB00495ZidovudineReverse transcriptase/RNaseHtarget
DB00495ZidovudineSolute carrier family 22 member 2transporter
DB00495ZidovudineSolute carrier family 22 member 6transporter
DB00495ZidovudineSolute carrier family 22 member 7transporter
DB00495ZidovudineSolute carrier family 22 member 8transporter
DB00495ZidovudineSolute carrier family 22 member 11transporter
DB00495ZidovudineSodium/nucleoside cotransporter 1transporter
DB00495ZidovudineEquilibrative nucleoside transporter 2transporter
DB00495ZidovudineP-glycoprotein 1transporter
DB00495ZidovudineMultidrug resistance-associated protein 4transporter
DB00495ZidovudineMultidrug resistance-associated protein 5transporter
DB00495ZidovudineATP-binding cassette sub-family G member 2transporter
DB00495ZidovudineTelomerase reverse transcriptasetarget
DB00495ZidovudineThymidine kinase, cytosolicenzyme
DB00495ZidovudineUDP-glucuronosyltransferase 2B7enzyme
DB00495ZidovudineUDP-glucuronosyltransferase 1-1enzyme
DB01606TazobactamBeta-lactamase TEMtarget
DB01606TazobactamSolute carrier family 22 member 6transporter
DB01606TazobactamSolute carrier family 22 member 8transporter
DB01606TazobactamBeta-lactamase Ohio-1target
DB01606TazobactamBeta-lactamase SHV-1target
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter