Crenezumab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Crenezumab
Accession Number
DB11959
Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Description

Crenezumab has been used in trials studying the treatment of Alzheimer's Disease.

Protein chemical formula
Not Available
Protein average weight
Not Available
Sequences
Not Available
Synonyms
Not Available
External IDs
MABT5102A
Categories
UNII
O8AS5277H0
CAS number
1095207-05-8

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Crenezumab.
AbituzumabThe risk or severity of adverse effects can be increased when Crenezumab is combined with Abituzumab.
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with Crenezumab.
AdecatumumabThe risk or severity of adverse effects can be increased when Adecatumumab is combined with Crenezumab.
AducanumabThe risk or severity of adverse effects can be increased when Crenezumab is combined with Aducanumab.
AfelimomabThe risk or severity of adverse effects can be increased when Afelimomab is combined with Crenezumab.
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with Crenezumab.
AlirocumabThe risk or severity of adverse effects can be increased when Alirocumab is combined with Crenezumab.
AmatuximabThe risk or severity of adverse effects can be increased when Crenezumab is combined with Amatuximab.
AMG 108The risk or severity of adverse effects can be increased when AMG 108 is combined with Crenezumab.
Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Substance
347911262
Wikipedia
Crenezumab

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedTreatmentHealthy Volunteers2
2Active Not RecruitingTreatmentAlzheimer's Disease (AD)1
2CompletedTreatmentAlzheimer's Disease (AD)3
3Active Not RecruitingTreatmentAlzheimer's Disease (AD)1
3RecruitingTreatmentAlzheimer's Disease (AD)2

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Drug created on October 20, 2016 15:05 / Updated on November 02, 2018 07:18