| DB00001 | Lepirudin | A protein-based direct thrombin inhibitor used to reverse and prevent thrombus formation in heparin-induced thrombocytopenia. |
| DB00002 | Cetuximab | An endothelial growth factor receptor binding fragment used to treat colorectal cancer as well as squamous cell carcinoma of the head and neck. |
| DB00003 | Dornase alfa | A synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis. |
| DB00004 | Denileukin diftitox | A recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor. |
| DB00005 | Etanercept | A protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis. |
| DB00006 | Bivalirudin | A direct thrombin inhibitor used to treat heparin-induced thrombocytopenia and to prevent thrombosis during percutaneous coronary intervention. |
| DB00007 | Leuprolide | A protein-based luteinizing hormone antagonist used to treat prostate cancer, endometriosis, and precocious puberty. |
| DB00008 | Peginterferon alfa-2a | A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses. |
| DB00009 | Alteplase | A recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. |
| DB00010 | Sermorelin | For the treatment of dwarfism, prevention of HIV-induced weight loss |
| DB00011 | Interferon alfa-n1 | A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus. |
| DB00012 | Darbepoetin alfa | A recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia. |
| DB00013 | Urokinase | A low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines. |
| DB00014 | Goserelin | A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary. |
| DB00015 | Reteplase | A purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. |
| DB00016 | Erythropoietin | A recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia. |
| DB00017 | Salmon calcitonin | A synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease. |
| DB00018 | Interferon alfa-n3 | A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus. |
| DB00019 | Pegfilgrastim | A recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy. |
| DB00020 | Sargramostim | A modified form of recombinant human granulocyte-macrophage colony stimulating factor used to increase immune cell production after myelosuppressive therapy or bone marrow transplant. |
| DB00022 | Peginterferon alfa-2b | A purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers. |
| DB00024 | Thyrotropin alfa | A recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue. |
| DB00025 | Antihemophilic factor, human recombinant | A form of recombinant coagulation Factor VIII used to treat hemophilia A, von Willebrand disease, and Factor XIII deficiency. |
| DB00026 | Anakinra | A recombinant form of human interleukin-1 receptor antagonist used in the treatment of rheumatoid arthritis and neonatal-onset multisystem inflammatory disease. |
| DB00027 | Gramicidin D | A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections. |
| DB00028 | Human immunoglobulin G | A purified form of human immunoglobulin G and other proteins used to treat immunodeficiency and a wide variety of autoimmune disorders. |
| DB00029 | Anistreplase | A form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. |
| DB00030 | Insulin human | A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. |
| DB00031 | Tenecteplase | A modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. |
| DB00032 | Menotropins | A purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility. |
| DB00033 | Interferon gamma-1b | A form of recombinant human interferon used to treat infections associated with chronic granulomatous disease and to slow the progression of severe malignant osteopetrosis. |
| DB00035 | Desmopressin | A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia. |
| DB00036 | Coagulation factor VIIa Recombinant Human | A form of recombinant human coagulation Factor VII used to treat hemophilia A and B. |
| DB00038 | Oprelvekin | A form of recombinant interleukin-11 used to stimulate production of megakaryocytes and platelets in patients with or at risk of thrombocytopenia after chemotherapy. |
| DB00039 | Palifermin | A form of recombinant human keratinocyte growth factor used to prevent and treat oral mucositis following radiation or chemotherapy. |
| DB00040 | Glucagon | A form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures. |
| DB00041 | Aldesleukin | A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma. |
| DB00042 | Botulinum Toxin Type B | A purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea. |
| DB00043 | Omalizumab | A monoclonal anti-immunoglobulin E antibody used in the treatment of severe asthma and chronic idiopathic urticaria. |
| DB00046 | Insulin lispro | A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. |
| DB00047 | Insulin glargine | A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. |
| DB00050 | Cetrorelix | A synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy. |
| DB00051 | Adalimumab | A monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. |
| DB00052 | Somatotropin | A form of recombinant human growth hormone used to treat dwarfism, growth hormone deficiency, and acromegaly as well as to prevent weight loss in HIV patients. |
| DB00054 | Abciximab | A monoclonal anti-glycoprotein IIb/IIIa receptor antibody used to prevent thrombosis during percutaneous coronary intervention. |
| DB00055 | Drotrecogin alfa | A form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII. |
| DB00056 | Gemtuzumab ozogamicin | A monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia. |
| DB00057 | Indium In-111 satumomab pendetide | For diagnosis of extrahepatic malignant cancers |
| DB00058 | Alpha-1-proteinase inhibitor | A purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency. |
| DB00060 | Interferon beta-1a | A form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis. |
| DB00062 | Albumin human | A purified form of human serum albumin used to replace lost albumin in patients with hypoalbuminemia, to treat hypovolemia and ascites, and as a part of some diagnostic imaging kits. |
| DB00063 | Eptifibatide | A peptide-based antagonist for glycoprotein IIb/IIIa used in the medical management of myocardial infarction and as an adjunct to percutaneous coronary intervention. |
| DB00065 | Infliximab | A monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. |
| DB00066 | Follitropin | A form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism. |
| DB00067 | Vasopressin | A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. |
| DB00068 | Interferon beta-1b | A form of recombinant human interferon used to slow the progression of relapsing multiple sclerosis and to reduce the frequency of clinical symptoms. |
| DB00069 | Interferon alfacon-1 | A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections. |
| DB00071 | Insulin pork | A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. |
| DB00072 | Trastuzumab | A monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers. |
| DB00073 | Rituximab | A monoclonal anti-CD20 antibody used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Wegener's granulomatosis, pemphigus vulgaris, and rheumatoid arthritis. |
| DB00074 | Basiliximab | A monoclonal anti-C25 antibody (interleukin-2 receptor alpha subunit) used as immunosuppressive therapy in kidney transplant patients. |
| DB00075 | Muromonab | A monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients. |
| DB00078 | Ibritumomab tiuxetan | A monoclonal anti-CD20 antibody used to treat B-cell non-Hodgkin's lymphoma via a conjugated radioactive isotope. |
| DB00080 | Daptomycin | A cyclic lipopeptide antibiotic used to treat complicated skin infections and bacteremia due to Staphylococcus aureus. |
| DB00081 | Tositumomab | A monoclonal anti-CD20 antibody used to treat B-cell non-Hodgkin's lymphoma via a conjugated radioactive isotope. |
| DB00082 | Pegvisomant | A growth hormone receptor antagonist used to treat acromegaly. |
| DB00083 | Botulinum toxin type A | A purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications. |
| DB00086 | Streptokinase | A purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism. |
| DB00087 | Alemtuzumab | A monoclonal anti-CD52 antibody used in the treatment of B-cell chronic lymphocytic leukemia and relapsing forms of multiple sclerosis. |
| DB00089 | Capromab pendetide | A monoclonal anti-prostate specific membrane antigen antibody used in imaging kits to target radioactive agents to malignant prostate tissue. |
| DB00092 | Alefacept | A recombinant fusion protein that binds CD2 and is used treat moderate to severe plaque psoriasis. |
| DB00093 | Felypressin | For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. |
| DB00094 | Urofollitropin | A form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure. |
| DB00095 | Efalizumab | A monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis. |
| DB00098 | Antithymocyte immunoglobulin (rabbit) | A purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants. |
| DB00099 | Filgrastim | A form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy. |
| DB00102 | Becaplermin | A recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area. |
| DB00103 | Agalsidase beta | A form of recombinant human alpha-galactosidase A enzyme used to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide. |
| DB00104 | Octreotide | A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors. |
| DB00106 | Abarelix | For palliative treatment of advanced prostate cancer. |
| DB00107 | Oxytocin | A recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding. |
| DB00108 | Natalizumab | A monoclonal anti-integrin antibody which binds to the alpha 4 subunit of integrins to prevent migration of immune cells, and is used to treat Crohn's disease or multiple sclerosis. |
| DB00109 | Enfuvirtide | An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. |
| DB00110 | Palivizumab | A monoclonal anti respiratory syncytial virus F protein antibody used to prevent serious sequelae caused by respiratory syncytial virus infection in pediatric patients. |
| DB00111 | Daclizumab | A monoclonal anti-CD25 antibody that blocks the interleukin-2 receptor which is used to treat relapsing forms of multiple sclerosis. |
| DB00112 | Bevacizumab | A monoclonal anti-vascular endothelial growth factor antibody used in the treatment of many cancer types in combination with other antineoplastics. |
| DB00113 | Technetium Tc-99m arcitumomab | For imaging colorectal tumors |
| DB00117 | Histidine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00118 | Ademetionine | S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... |
| DB00120 | Phenylalanine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00123 | L-Lysine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00125 | Arginine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00128 | Aspartic acid | An amino acid commonly found as a component in total parenteral nutrition. |
| DB00130 | L-Glutamine | An amino acid commonly found as a component in total parenteral nutrition. |
| DB00133 | Serine | An amino acid commonly found as a component in total parenteral nutrition. |
| DB00134 | Methionine | An amino acid commonly found as a component in total parenteral nutrition. |
| DB00135 | Tyrosine | An amino acid commonly found as a component in total parenteral nutrition. |
| DB00138 | Cystine | An oxidated derivative of the amino acid cysteine found in various nutritional products and creams to treat cervical injury or inflammation. |
| DB00142 | Glutamic acid | An amino acid commonly found as a component in total parenteral nutrition. |
| DB00143 | Glutathione | For nutritional supplementation, also for treating dietary shortage or imbalance |
| DB00145 | Glycine | An amino acid commonly used as a component of total parenteral nutrition and is also used as irrigation during surgery. |
| DB00148 | Creatine | For nutritional supplementation, also for treating dietary shortage or imbalance. |
| DB00149 | Leucine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00150 | Tryptophan | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00151 | Cysteine | An amino acid commonly found as a component of total parenteral nutrition and used as an antidote for acetaminophen overdose. |
| DB00155 | Citrulline | Used for nutritional supplementation, also for treating dietary shortage or imbalance. |
| DB00156 | Threonine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00160 | Alanine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00161 | Valine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00167 | Isoleucine | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00168 | Aspartame | Used as a diet supplement and sugar substitute. |
| DB00172 | Proline | An amino acid commonly found as a component of total parenteral nutrition. |
| DB00174 | Asparagine | Used for nutritional supplementation, also for treating dietary shortage or imbalance. |
| DB00181 | Baclofen | A GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients. |
| DB00183 | Pentagastrin | A gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors. |
| DB00230 | Pregabalin | An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants. |
| DB00260 | Cycloserine | A broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI). |
| DB00290 | Bleomycin | A chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others. |
| DB00314 | Capreomycin | An aminoglycoside antibiotic used as an adjunct drug in tuberculosis. |
| DB00362 | Anidulafungin | An antifungal used in the treatment of several types of candida infections. |
| DB00403 | Ceruletide | Caerulein is used in the treatment of paralytic ileus and as diagnostic aid in pancreatic malfunction. |
| DB00420 | Promazine | A phenothiazine used to manage schizophrenia. |
| DB00451 | Levothyroxine | A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. |
| DB00492 | Fosinopril | An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. |
| DB00509 | Dextrothyroxine | A thyroid hormone used to treat hyperlipidemia. |
| DB00512 | Vancomycin | A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. |
| DB00513 | Aminocaproic acid | An antifibrinolytic agent used to induce clotting postoperatively. |
| DB00520 | Caspofungin | An echinocandin used to treat a variety of fungal infections. |
| DB00556 | Perflutren | A diagnostic medication to improve contrast during echocardiograms. |
| DB00577 | Valaciclovir | An guanine nucleoside antiviral used to treat herpes exacerbations. |
| DB00584 | Enalapril | A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. |
| DB00626 | Bacitracin | A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. |
| DB00642 | Pemetrexed | A folate analog used to treat mesothelioma and non-small cell lung cancer. |
| DB00644 | Gonadorelin | A synthetic GnRH used to test the function of gonadotropes and the pituitary. |
| DB00666 | Nafarelin | A gonadotropin releasing hormone agonist used to treat central precocious puberty. |
| DB00722 | Lisinopril | An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. |
| DB00731 | Nateglinide | A meglitinide used to treat non insulin dependent diabetes mellitus. |
| DB00765 | Metyrosine | A tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma. |
| DB00775 | Tirofiban | A platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. |
| DB00803 | Colistin | A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. |
| DB00837 | Progabide | Indicated for the treatment of epilepsy. |
| DB00855 | Aminolevulinic acid | A porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma. |
| DB00859 | Penicillamine | A chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis. |
| DB00968 | Methyldopa | An alpha-2 adrenergic agonist used to treat hypertension. |
| DB00970 | Dactinomycin | An actinomycin used to treat a wide variety of cancers. |
| DB00992 | Methyl aminolevulinate | A porphyrin precursor used to treat non-hyperkeratotic, non-pigmented actinic keratosis of the face and scalp. |
| DB00996 | Gabapentin | An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. |
| DB01042 | Melphalan | An alkylating antineoplastic agent used to treat multiple myeloma and ovarian carcinoma. |
| DB01055 | Mimosine | Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca. |
| DB01072 | Atazanavir | An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
| DB01080 | Vigabatrin | An irreversible GABA transaminase inhibitor used as an adjunct to treat refractory complex partial seizures in patients ≥10 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years. |
| DB01111 | Colistimethate | An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa. |
| DB01141 | Micafungin | An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. |
| DB01197 | Captopril | An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. |
| DB01221 | Ketamine | A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. |
| DB01235 | Levodopa | A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. |
| DB01257 | Eculizumab | A recombinant humanized monoclonal antibody used to reduce the risk of hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). |
| DB01269 | Panitumumab | A recombinant humanized monoclonal antibody used to treat EGFR-expressing, metastatic colorectal carcinoma that is refractory to fluoropyrimidine-, oxaliplatin-, and irinotecan- containing chemotherapy regimens. |
| DB01270 | Ranibizumab | A recombinant humanized monoclonal antibody and VEGF-A antagonist used for the management of macular edema after retinal vein occlusion, age-related macular degeneration (wet), and diabetic macular edema. |
| DB01276 | Exenatide | A GLP-1 agonist used in the management of type 2 diabetes mellitus. |
| DB01277 | Mecasermin | A recombinant insulin-like growth factor-1 used for the long-term treatment of growth failure in pediatric patients with primary IGF-1 deficiency or with growth hormone gene deletion due to the development of neutralizing antibodies to GH. |
| DB01278 | Pramlintide | An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. |
| DB01279 | Galsulfase | A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. |
| DB01281 | Abatacept | A disease-modifying antirheumatic drug (DMARD) used for the management of moderate-to-severe active rheumatoid arthritis and active polyarticular juvenile idiopathic arthritis as monotherapy or in combination with other DMARDs. |
| DB01282 | Carbetocin | An oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth. |
| DB01284 | Tetracosactide | A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. |
| DB01285 | Corticotropin | A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. |
| DB01306 | Insulin aspart | A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. |
| DB01307 | Insulin detemir | A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. |
| DB01309 | Insulin glulisine | A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. |
| DB01348 | Spirapril | Spirapril is an ACE inhibitor class drug used to treat hypertension. |
| DB01369 | Quinupristin | An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections. |
| DB01373 | Calcium | A mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency. |
| DB01423 | Stepronin | Strepronin is a mucolytic (expectorant) drug. |
| DB01583 | Liotrix | May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... |
| DB01584 | Thyroglobulin | For the treatment of hypothyroidism (deficiency in the production of thyroid hormone). |
| DB01646 | N-Acetylmethionine | Not Available |
| DB01669 | Virginiamycin M1 | For the treatment of bacterial infections. |
| DB01683 | Chymostatin | Not Available |
| DB01686 | N,N-dimethylarginine | Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which... |
| DB01764 | Dalfopristin | An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes. |
| DB01783 | Pantothenic acid | A vitamin B5 found in various nutritional supplements. |
| DB01853 | Bacteriochlorophyll A | A specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A. |
| DB02011 | N-(Phosphonoacetyl)-L-Ornithine | Not Available |
| DB02083 | N,N-dimethylglycine | Not Available |
| DB02109 | Hadacidin | Not Available |
| DB02123 | Glycochenodeoxycholic Acid | A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed.... |
| DB02137 | Molybdenum cofactor | Absence of molybdenum cofactor leads to accumulation of toxic levels of sulphite and neurological damage usually leading to death within months of birth, due to the lack of active sulfite... |
| DB02216 | S-Methylcysteine | Not Available |
| DB02235 | L-methionine (R)-S-oxide | Not Available |
| DB02236 | Glycinamide Ribonucleotide | Not Available |
| DB02255 | Ilomastat | Not Available |
| DB02261 | Platelet Activating Factor | Not Available |
| DB02274 | 7-Keto-8-Aminopelargonic Acid | Not Available |
| DB02307 | N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine | Not Available |
| DB02341 | Mdl 101,146 | Not Available |
| DB02345 | Selenocysteine | A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and... |
| DB02386 | Leucine Phosphonic Acid | Not Available |
| DB02518 | N-Acetylalanine | Not Available |
| DB02543 | Pyrrole-2-Carboxylate | Not Available |
| DB02557 | Phosphoramidon | Not Available |
| DB02578 | N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine | Not Available |
| DB02601 | 4-Hydroxyphenylglycine | Not Available |
| DB02638 | Terlipressin | Commonly used to stop bleeding of varices in the food pipe (oesophagus). |
| DB02655 | D-Aspartic Acid | The D-isomer of aspartic acid. [PubChem] |
| DB02810 | N-(2-Acetamido)Iminodiacetic Acid | Not Available |
| DB02821 | Canaline | Not Available |
| DB02855 | N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline | Not Available |
| DB02952 | 2-aminoisobutyric acid | Not Available |
| DB02959 | Oxitriptan | For use as an antidepressant, appetite suppressant, and sleep aid. |
| DB02975 | GE-2270A | Not Available |
| DB02978 | Beta-Hydroxyleucine | Not Available |
| DB02999 | Quisqualic acid | Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular... |
| DB03032 | S-octylglutathione | Not Available |
| DB03088 | Pidolic acid | There is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication.
Although pidolic acid may be sold in... |
| DB03107 | Beta-Alanine | An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a... |
| DB03144 | N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine | Not Available |
| DB03157 | N,O-Didansyl-L-Tyrosine | Not Available |
| DB03214 | Vinylglycine | Vinylglycine is an irreversible inhibitor of aspartate aminotransferase. |
| DB03223 | Diphthamide | Not Available |
| DB03251 | RWJ-51084 | Not Available |
| DB03295 | Glutathionylspermidine | Not Available |
| DB03360 | N-Acetylproline | Not Available |
| DB03380 | L-tyrosinamide | Not Available |
| DB03395 | Enalkiren | Not Available |
| DB03408 | gamma-Glutamylcysteine | Not Available |
| DB03424 | Ubenimex | An adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia. |
| DB03425 | 2s,4r-4-Methylglutamate | Not Available |
| DB03436 | Gallichrome | Not Available |
| DB03458 | N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid | N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. |
| DB03459 | Sparfosic acid | Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen... |
| DB03470 | Trypanothione | Not Available |
| DB03535 | Z-Pro-Prolinal | Not Available |
| DB03544 | S-Phosphocysteine | Not Available |
| DB03552 | 3-Tyrosine | Not Available |
| DB03632 | Argifin | Not Available |
| DB03640 | Beta-Hydroxyaspartic Acid | Not Available |
| DB03660 | 4-Iodo-L-phenylalanine | Not Available |
| DB03709 | Bicine | Not Available |
| DB03799 | Trifluoromethionine | Not Available |
| DB03817 | L-2,4-diaminobutyric acid | Not Available |
| DB03880 | Batimastat | Not Available |
| DB03889 | S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione | Not Available |
| DB03940 | Oxamic Acid | Amino-substituted glyoxylic acid derivative. [PubChem] |
| DB04029 | Phenylalanine Amide | Not Available |
| DB04092 | Apstatin | Not Available |
| DB04111 | Balhimycin | Balhimycin is a novel glycopeptide antibiotic. |
| DB04129 | Willardiine | Willardiine is a compound isolated from seeds of Acacia willariana. |
| DB04132 | S-Hexylglutathione | Not Available |
| DB04167 | Aceglutamide | Not Available |
| DB04185 | Norvaline | Norvaline is an isomer of the more common amino acid valine. |
| DB04189 | N(2)-(2-carboxyethyl)-L-arginine | Not Available |
| DB04191 | Skf 107457 | Not Available |
| DB04217 | L-2-amino-3-butynoic acid | Not Available |
| DB04223 | Nitroarginine | An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in... |
| DB04269 | Cyclotheonamide A | Cyclotheonamide A is a cyclic peptide isolated from the marine sponge Theonella. |
| DB04284 | L-proline betaine | Not Available |
| DB04291 | Oxfenicine | Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA). |
| DB04308 | D-4-hydroxyphenylglycine | Not Available |
| DB04334 | 6-hydroxydopa quinone | Not Available |
| DB04350 | Argadin | Not Available |
| DB04370 | S-sulphocysteine | Not Available |
| DB04391 | Aeruginosin 98-B | Not Available |
| DB04418 | Adenylosuccinic acid | Not Available |
| DB04454 | Alpha-Aminobutyric Acid | Not Available |
| DB04464 | N-Formylmethionine | Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in... |
| DB04495 | Paratoulene phosphate | Not Available |
| DB04498 | Aspartate Semialdehyde | Not Available |
| DB04527 | beta-Hydroxyasparagine | Not Available |
| DB04539 | Glyphosate | Not Available |
| DB04584 | Phenyldehydroalanine | Not Available |
| DB04620 | Cycloleucine | Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments. |
| DB04676 | Dansyllysine | Not Available |
| DB04738 | Motuporin | Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey. |
| DB04798 | THIO-ATPA | Not Available |
| DB04805 | Virginiamycin S1 | One of the components of virginiamycin, a cyclic polypeptide antibiotic complex from streptomyces virginiae, s. Loidensis, s. Mitakaensis, s. Pristina-spiralis, s. Ostreogriseus, and others. It is used to treat infections... |
| DB04847 | Roxadustat | In clinical development for the treatment of anemia of chronic inflammatory disease. |
| DB04869 | Olcegepant | For the treatment of migraine headaches. |
| DB04894 | Vapreotide | For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea. |
| DB04897 | Lucinactant | Intended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. |
| DB04899 | Nesiritide | A recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. |
| DB04900 | Thymalfasin | Indicated as an adjuvant for influenza vaccine in elderly patients and as an adjuvant for both influenza and hepatitis B vaccines in chronic hemodialysis patients who failed to achieve adequate... |
| DB04901 | Galiximab | Investigated for use/treatment in lymphoma (non-hodgkin's), psoriasis and psoriatic disorders, bone metastases, multiple myeloma, prostate cancer, and rheumatoid arthritis. |
| DB04911 | Oritavancin | An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria. |
| DB04914 | G17DT | Intended for the treatment of various forms of cancer. |
| DB04921 | Dirucotide | For the treatment of multiple sclerosis (MS). |
| DB04925 | Desmoteplase | Investigated for use/treatment in cerebral ischemia and strokes. |
| DB04931 | Afamelanotide | An injectable subcutaneous implant used to mitigate phototoxicity secondary to erythropoietic protoporphyria (EPP). |
| DB04945 | Hemoglobin | An iron-containing protein found in all red blood cells (RBCs) for proper binding of oxygen and transport throughout the body, included in blood transfusions in severe hemorrhage. |
| DB04949 | Pexelizumab | For the treatment of inflammation during cardiac surgery. |
| DB04952 | Ramoplanin | For the treatment of bacterial infections. |
| DB04956 | Afelimomab | Investigated for use/treatment in sepsis and septicemia. |
| DB04958 | Epratuzumab | Investigated for use/treatment in leukemia (lymphoid), lymphoma (non-hodgkin's), and systemic lupus erythematosus. |
| DB04962 | Bectumomab | Investigated for use/treatment in lymphoma (non-hodgkin's). |
| DB04964 | Oregovomab | Investigated for use/treatment in ovarian cancer. |
| DB04972 | Canfosfamide | Intended for the treatment of various forms of cancer. |
| DB04977 | Plitidepsin | Intended for the treatment of various forms of cancer. |
| DB04985 | Tigapotide | For the treatment of late stage Hormone Refractory Prostate Cancer (HRPC) for which no effective therapy currently exists. |
| DB04988 | IGN311 | Intended for the treatment of various forms of cancer. |
| DB05006 | Adecatumumab | Investigated for use/treatment in breast cancer and prostate cancer. |
| DB05012 | XEN2174 | For the treatment of chronic cancer pain. |
| DB05029 | Lancovutide | Investigated for use/treatment in cystic fibrosis and eye disorders/infections. |
| DB05032 | REV131 | Investigated for use/treatment in allergic reaction, allergic rhinitis, and cataracts. |
| DB05034 | Ularitide | Investigated for use/treatment in congestive heart failure. |
| DB05084 | Abaloparatide | A parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in postmenopausal women with a high risk of fracture. |
| DB05092 | CDP323 | Investigated for use/treatment in multiple sclerosis. |
| DB05096 | LY2140023 | Investigated for use/treatment in psychosis and schizophrenia and schizoaffective disorders. |
| DB05097 | Labetuzumab | Labetuzumab is a humanized monoclonal antibody used to treat cancer. Retrieved from "http://en.wikipedia.org/wiki/Labetuzumab" |
| DB05098 | Leptin | Investigated for use/treatment in lipodystrophy and obesity. |
| DB05101 | Matuzumab | Investigated for use/treatment in cervical dysplasia/cancer, colorectal cancer, gastric cancer, and lung cancer. |
| DB05111 | Fontolizumab | Investigated for use/treatment in crohn's disease and psoriasis and psoriatic disorders. |
| DB05115 | NN344 | Investigated for use/treatment in diabetes mellitus type 1 and 2. |
| DB05128 | Aminocandin | Investigated for use/treatment in fungal infections. |
| DB05130 | INCB3284 | Investigated for use/treatment in inflammatory disorders (unspecified). |
| DB05136 | Bavituximab | Investigated for use/treatment in breast cancer, cancer/tumors (unspecified), HIV infection, hepatitis (viral, C), and solid tumors. |
| DB05139 | CR002 | Investigated for use/treatment in nephropathy. |
| DB05155 | CR665 | Investigated for use/treatment in pain (acute or chronic). |
| DB05158 | PM02734 | Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors. |
| DB05160 | Topsalysin | Investigated for use/treatment in benign prostatic hyperplasia, cancer/tumors (unspecified), prostate cancer, prostate disorders, and solid tumors. |
| DB05161 | Elafin | Investigated for use/treatment in inflammatory disorders (unspecified). |
| DB05199 | LX1031 | Irritable bowel syndrome (IBS) and other gastrointestinal disorders |
| DB05209 | Rozrolimupab | Investigated for use/treatment in thrombocytopenia. |
| DB05210 | SF1126 | For the treatment of various forms of cancer. |
| DB05258 | Interferon alfa | Investigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma. |
| DB05259 | Glatiramer | An immunomodulator used to reduce the frequency of relapses in Multiple Sclerosis (MS). |
| DB05276 | Hepatitis B Immune Globulin | An injection of immunoglobulin G (IgG) antibodies to prevent the development of chronic Hepatitis B infection. |
| DB05299 | keyhole limpet hemocyanin | Investigated for use/treatment in bladder cancer and solid tumors. |
| DB05305 | Cintredekin Besudotox | Investigated for use/treatment in brain cancer. |
| DB05311 | Ecallantide | A kallikrein inhibitor used to prevent and treat acute attacks caused by Hereditary Angioedema (HAE). |
| DB05319 | Oportuzumab monatox | Investigated for use/treatment in bladder cancer and head and neck cancer. |
| DB05332 | Romiplostim | A fusion protein thrombopoietin (TPO) peptide analog that increases platelet counts by binding to and activating the human TPO receptor. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP). |
| DB05336 | Obiltoxaximab | A monoclonal antibody used for prophylaxis or treatment of inhalational anthrax. |
| DB05344 | Ciliary neurotrophic factor | Investigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified). |
| DB05393 | NOV-002 | Investigated for use/treatment in breast cancer, lung cancer, and ovarian cancer. |
| DB05394 | Corticorelin | Investigated for use/treatment in brain cancer and neurologic disorders. |
| DB05396 | Albinterferon Alfa-2B | Investigated for use/treatment in hepatitis (viral, C). |
| DB05405 | XTL-001 | Investigated for use/treatment in hepatitis (viral, B). |
| DB05413 | Tifuvirtide | Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection. |
| DB05434 | ABT-510 | Investigated for use/treatment in lymphoma (unspecified), melanoma, and solid tumors. |
| DB05437 | NAV 1800 | Investigated for use/treatment in colorectal cancer and solid tumors. |
| DB05446 | LJP 1082 | Investigated for use/treatment in autoimmune diseases, strokes, and thrombosis. |
| DB05459 | Briakinumab | Investigated for use/treatment in autoimmune diseases, crohn's disease, multiple sclerosis, psoriasis and psoriatic disorders, and rheumatoid arthritis. |
| DB05460 | Ezatiostat | Investigated for use/treatment in myelodysplastic syndrome. |
| DB05475 | Golotimod | Investigated for use/treatment in hepatitis (viral, C), infectious and parasitic disease (unspecified), and tuberculosis. |
| DB05476 | WX-UK1 | Investigated for use/treatment in solid tumors. |
| DB05496 | Otelixizumab | Investigated for use/treatment in diabetes mellitus type 1, pediatric indications, and psoriasis and psoriatic disorders. |
| DB05507 | VX-765 | Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders. |
| DB05518 | Managlinat dialanetil | Investigated for use/treatment in diabetes mellitus type 2. |
| DB05521 | Telaprevir | An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. |
| DB05540 | Alanosine | Investigated for use/treatment in brain cancer and cancer/tumors (unspecified). |
| DB05545 | AMG 108 | Investigated for use/treatment in osteoarthritis and rheumatoid arthritis. |
| DB05550 | Iratumumab | Investigated for use/treatment in lymphoma (unspecified). |
| DB05555 | Enokizumab | Investigated for use/treatment in asthma. |
| DB05560 | Delcasertib | Investigated for use/treatment in myocardial infarction. |
| DB05578 | Ramucirumab | An antineoplastic agent and direct VEGFR2 (vascular endothelial growth factor receptor 2) antagonist that blocks the binding of natural VEGF ligands, which are secreted by solid tumors to promote angiogenesis and enhance tumor blood supply. |
| DB05584 | Praconase | Investigated for use/treatment in spinal cord injuries. |
| DB05595 | Farletuzumab | Investigated for use/treatment in ovarian cancer. |
| DB05599 | Fibroblast growth factor-1 | Investigated for use/treatment in coronary artery disease and peripheral vascular disease. |
| DB05625 | CTCE-9908 | Investigated for use/treatment in cancer/tumors (unspecified), lung cancer, and sarcoma. |
| DB05633 | Glypromate | Investigated for use/treatment in neurologic disorders. |
| DB05645 | Larazotide | Investigated for use/treatment in autoimmune diseases, diabetes mellitus type 1, and gastrointestinal diseases and disorders (miscellaneous). |
| DB05656 | Veltuzumab | Investigated for use/treatment in lymphoma (non-hodgkin's). |
| DB05660 | D-JNKI-1 | Investigated for use/treatment in hearing loss. |
| DB05668 | Palifosfamide | Investigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma. |
| DB05675 | EP-2104R | Investigated for use/treatment in cardiovascular disorders and thrombosis. |
| DB05679 | Ustekinumab | A targeted antibody therapy used to manage inflammatory conditions such as plaque psoriasis, psoriatic arthritis, Crohn's Disease, and ulcerative colitis. |
| DB05687 | BL-1020 | Investigated for use/treatment in schizophrenia and schizoaffective disorders. |
| DB05713 | LY-517717 | Investigated for use/treatment in thrombosis and venous thromboembolism. |
| DB05714 | Flovagatran | Investigated for use/treatment in thrombosis. |
| DB05718 | Maxy-G34 | Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics. |
| DB05735 | Cefilavancin | Investigated for use/treatment in bacterial infection, skin infections/disorders, and staph bacterial infections. |
| DB05739 | CYT006-AngQb | Investigated for use/treatment in hypertension. |
| DB05773 | Trastuzumab emtansine | An antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer. |
| DB05777 | Thrombomodulin Alfa | Investigated for use/treatment in blood preservative, blood (blood forming organ disorders, unspecified), sepsis and septicemia, and thrombosis. |
| DB05779 | Oglufanide | Investigated for use/treatment in hepatitis (viral, C). |
| DB05793 | PRO-542 | Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, HIV infection, and pediatric indications. |
| DB05797 | TNX-901 | Investigated for use/treatment in allergic reaction. |
| DB05819 | NBI-6024 | Investigated for use/treatment in diabetes mellitus type 1 and pediatric indications. |
| DB05829 | Parathyroid hormone | An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism. |
| DB05864 | PPI-2458 | Investigated for use/treatment in lymphoma (non-hodgkin's) and solid tumors. |
| DB05889 | Inotuzumab ozogamicin | An antibody-drug conjugate used to treat B-cell precursor acute lymphoblastic leukemia (ALL). |
| DB05892 | RI 624 | Investigated for use/treatment in pain (acute or chronic). |
| DB05915 | MYO-029 | Investigated for use/treatment in muscular dystrophy. |
| DB05931 | Pegdinetanib | Investigated for use/treatment in cancer/tumors (unspecified) and macular degeneration. |
| DB05934 | CTCE-0214 | Investigated for use/treatment in adverse effects (chemotherapy), blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), neutropenics, and vascular diseases. |
| DB05941 | Leronlimab | Investigated for use/treatment in HIV infection. |
| DB05942 | GI-5005 | Investigated for use/treatment in hepatitis (viral, C). |
| DB05996 | Glembatumumab vedotin | Investigated for use/treatment in melanoma. |
| DB06043 | Olaratumab | A platelet-derived growth factor receptor alpha blocking antibody used with doxorubicin to treat patients with certain types of soft tissue sarcoma (STS). |
| DB06045 | Trofinetide | Investigated for use/treatment in traumatic brain injuries. |
| DB06049 | IPH 2101 | Investigated for use/treatment in leukemia (myeloid) and multiple myeloma. |
| DB06050 | TB-402 | Investigated for use/treatment in atrial fibrillation and thrombosis. |
| DB06081 | Caplacizumab | A von Willebrand factor (vWF)-directed antibody fragment used to treat acquired thrombotic thrombocytopenic purpura (aTTP). |
| DB06087 | Friulimicin B | Investigated for use/treatment in bacterial infection. |
| DB06101 | IMC-1C11 | Investigated for use/treatment in cancer/tumors (unspecified). |
| DB06116 | Eldelumab | Investigated for use/treatment in ulcerative colitis. |
| DB06138 | IRL-1620 | Investigated for use/treatment in cancer/tumors (unspecified). |
| DB06149 | Teicoplanin | For the treatment of bacterial infections caused by susceptible microorganisms. |
| DB06151 | Acetylcysteine | A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. |
| DB06162 | Lumiliximab | Investigated for use/treatment in asthma and leukemia (lymphoid). |
| DB06168 | Canakinumab | An interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA). |
| DB06171 | Paclitaxel trevatide | Investigated for use/treatment in brain cancer. |
| DB06176 | Romidepsin | A histone deacetylase (HDAC) inhibitor used to treat cutaneous and peripheral T-cell lymphoma. |
| DB06178 | Talotrexin | Investigated for use/treatment in solid tumors, lung cancer, leukemia (unspecified), and leukemia (lymphoid). |
| DB06179 | Darinaparsin | Investigated for use/treatment in blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), solid tumors, multiple myeloma, and liver cancer. |
| DB06182 | Talabostat | Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), lung cancer, melanoma, and pancreatic cancer. |
| DB06186 | Ipilimumab | A human cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody used to treat metastatic or unresectable melanoma. |
| DB06192 | Nimotuzumab | Investigated for use/treatment in head and neck cancer, brain cancer, pediatric indications, pancreatic cancer, lung cancer, and colorectal cancer. |
| DB06196 | Icatibant | A bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE). |
| DB06219 | Dalbavancin | An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria. |
| DB06241 | Clenoliximab | Investigated for use/treatment in rheumatoid arthritis. |
| DB06243 | Eflornithine | A medication used topically to reduce unwanted facial hair growth in women. The postulated mechanism of action is through irreversible inhibition of ornithine decarboxylase (ODC) in the skin. |
| DB06244 | Trafermin | Investigated for use/treatment in coronary artery disease, peripheral vascular disease, periodontal disease, bone fractures, entero-related fistulae, and diabetic foot ulcers. |
| DB06245 | Lanoteplase | Investigated for use/treatment in myocardial infarction. |
| DB06260 | Aviptadil | Not Annotated |
| DB06261 | Hexaminolevulinate | An optical imaging agent used to perform Blue Light Cystoscopy (BLC™) in order to detect carcinoma of the bladder. |
| DB06262 | Droxidopa | A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. |
| DB06273 | Tocilizumab | An interleukin-6 (IL-6) receptor antagonist used to treat Cytokine Release Syndrome (CRS), Systemic Juvenile Idiopathic Arthritis (sJIA), Giant Cell Arteritis (GCA), and Rheumatoid Arthritis (RA). |
| DB06285 | Teriparatide | A recombinant parathyroid hormone used for the treatment of osteoporosis. |
| DB06304 | BIIB015 | Investigated for use/treatment in solid tumors. |
| DB06310 | Motavizumab | Investigated for use/treatment in viral infection and pediatric indications. |
| DB06317 | Elotuzumab | An antineoplastic agent and SLAMF7-directed immunostimulatory antibody used for the treatment of refractory multiple myeloma in combination with other antineoplastic agents. |
| DB06318 | AVE9633 | Investigated for use/treatment in leukemia (myeloid). |
| DB06322 | Carotuximab | Investigated for use/treatment in solid tumors. |
| DB06323 | AZX-100 | Investigated for use/treatment in scar tissue. |
| DB06324 | XmAb 2513 | Investigated for use/treatment in lymphoma (unspecified) and lymphoma (non-hodgkin's). |
| DB06335 | Saxagliptin | An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. |
| DB06342 | Coltuximab ravtansine | Investigated for use/treatment in lymphoma (non-hodgkin's). |
| DB06343 | Teprotumumab | A fully human monoclonal antibody directed against insulin-like growth factor-1 receptor for the treatment of thyroid eye disease. |
| DB06360 | Lucatumumab | Investigated for use/treatment in leukemia (lymphoid), multiple myeloma, and lymphoma (unspecified). |
| DB06366 | Pertuzumab | An antineoplastic agent used in the treatment of HER2-positive metastatic breast cancer in combination with other antineoplastic agents. |
| DB06371 | Siplizumab | Investigated for use/treatment in psoriasis and psoriatic disorders, transplant (rejection), graft versus host disease, lymphoma (unspecified), and leukemia (unspecified). |
| DB06372 | Rilonacept | An IL-1 inhibitor used to treat cryopyrin-associated periodic syndrome, a rare hereditary inflammatory disorder. |
| DB06379 | Calcitonin gene-related peptide | Investigated for use/treatment in myocardial infarction, heart disease, and asthma. |
| DB06399 | Atacicept | Investigated for use/treatment in autoimmune diseases, systemic lupus erythematosus, rheumatoid arthritis, multiple myeloma, lymphoma (non-hodgkin's), and leukemia (lymphoid). |
| DB06404 | Human C1-esterase inhibitor | A C1 inhibitor used to prevent angioedema attacks associated with hereditary angioedema. |
| DB06423 | Endostatin | Investigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy. |
| DB06434 | Repifermin | Investigated for use/treatment in bone marrow transplant, ulcers, and inflammatory bowel disease. |
| DB06437 | Tifacogin | Investigated for use/treatment in sepsis and septicemia and pneumonia. |
| DB06467 | Apolizumab | Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), and solid tumors. |
| DB06474 | Sibrotuzumab | Investigated for use/treatment in cancer/tumors (unspecified), colorectal cancer, and lung cancer. |
| DB06493 | Velafermin | Investigated for use/treatment in adverse effects (chemotherapy). |
| DB06495 | Onercept | Investigated for use/treatment in psoriasis and psoriatic disorders and crohn's disease. |
| DB06508 | GW-559090 | Investigated for use/treatment in asthma and allergic rhinitis. |
| DB06510 | Muraglitazar | Investigated for use/treatment in diabetes mellitus type 2. |
| DB06511 | AMGN-0007 | Investigated for use/treatment in osteoporosis and bone metastases. |
| DB06534 | Thrombopoietin | Investigated for use/treatment in thrombocytopenia. |
| DB06535 | Etilevodopa | Investigated for use/treatment in parkinson's disease. |
| DB06549 | Labradimil | Investigated for use/treatment in brain cancer and pediatric indications. |
| DB06550 | Bivatuzumab | Investigated for use/treatment in cancer/tumors (unspecified) and head and neck cancer. |
| DB06557 | Lerdelimumab | Investigated for use/treatment in glaucoma and cataracts. |
| DB06562 | Emfilermin | Investigated for use/treatment in adverse effects (chemotherapy), reproductive health, and infertility. |
| DB06576 | Baminercept | Investigated for use/treatment in rheumatoid arthritis. |
| DB06584 | TG4010 | Investigated for use/treatment in breast cancer, renal cell carcinoma, prostate cancer, and lung cancer. |
| DB06599 | Lexatumumab | Investigated for use/treatment in cancer/tumors (unspecified). |
| DB06602 | Reslizumab | An IL-5 antagonist used as an add-on maintenance treatment of patients with severe eosinophilic asthma in adults. |
| DB06606 | Teplizumab | Investigated for use/treatment in diabetes mellitus type 1. |
| DB06607 | Catumaxomab | For use in the management of malignant ascites tumours via intraperitoneal infusion where standard therapy is not available or feasible [FDA Label]. |
| DB06611 | Pegsunercept | Investigated for use/treatment in rheumatoid arthritis. |
| DB06612 | Mepolizumab | An IL-5 antagonist used as an add-on maintenance treatment of patients with severe eosinophilic asthma in adults. |
| DB06643 | Denosumab | A RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures. |
| DB06645 | Anamorelin | Investigated for use/treatment in cachexia and anorexia. |
| DB06647 | Volociximab | Investigated for use/treatment in solid tumors, renal cell carcinoma, melanoma, pancreatic cancer, lung cancer, and ovarian cancer. |
| DB06650 | Ofatumumab | A CD20 inhibitor used for the treatment of patients with chronic lymphocytic leukemia (CLL) refractory to fludarabine and alemtuzumab. |
| DB06654 | Safinamide | A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. |
| DB06655 | Liraglutide | A GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes. |
| DB06657 | Valrocemide | Investigated for use/treatment in epilepsy. |
| DB06663 | Pasireotide | A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate. |
| DB06674 | Golimumab | A TNFα inhibitor used in the symptomatic treatment of various active inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. |
| DB06679 | Amediplase | Investigated for use/treatment in myocardial infarction and thrombosis. |
| DB06681 | Belatacept | A selective T-cell costimulation blocker used in the prophylaxis of organ rejection in adult patients receiving a kidney transplant. |
| DB06692 | Aprotinin | A serine protease inhibitor used to reduce the risk for perioperative blood loss and the need for blood transfusion in high-risk patients during cardiopulmonary bypass for coronary artery bypass graft surgery. |
| DB06699 | Degarelix | A GnRH receptor antagonist used in the management of advanced prostate cancer. |
| DB06719 | Buserelin | A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. |
| DB06763 | Saralasin | Not Annotated |
| DB06775 | Carglumic acid | An analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency. |
| DB06785 | Ganirelix | A GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges. |
| DB06788 | Histrelin | A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer. |
| DB06791 | Lanreotide | A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly. |
| DB06794 | Lodoxamide | An ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. |
| DB06823 | Tiopronin | A thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria. |
| DB06825 | Triptorelin | A GnRH agonist indicated for the palliative treatment of advanced prostate cancer. |
| DB06827 | Viomycin | Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis. |
| DB07744 | Z-Val-Ala-Asp fluoromethyl ketone | Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the... |
| DB08508 | N-BENZOYL-D-ALANINE | Not Available |
| DB08626 | Thiorphan | A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms. |
| DB08847 | Hydroxyproline | Used in France as a combination product for the treatment of small, superficial wounds. |
| DB08856 | DADLE | A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate. |
| DB08861 | DPDPE | A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond. |
| DB08862 | Cholecystokinin | For use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency . |
| DB08869 | Tesamorelin | A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. |
| DB08870 | Brentuximab vedotin | A CD30-directed antibody-drug conjugate used to treat various types of lymphoma. |
| DB08872 | Gabapentin enacarbil | A gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). |
| DB08873 | Boceprevir | A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. |
| DB08879 | Belimumab | A B-lymphocyte stimulator (BLyS)-specific inhibitor that indirectly inhibits B cell survival, and is used to treat patients with autoantibody positive, active systemic lupus erythematosus. |
| DB08885 | Aflibercept | A vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy. |
| DB08888 | Ocriplasmin | A proteolytic enzyme used to treat symptomatic vitreomacular adhesion by dissolving the protein matrix responsible for the adhesion between the vitreous and macula. |
| DB08889 | Carfilzomib | A proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma. |
| DB08890 | Linaclotide | A guanylate cyclase-C agonist used to treat constipation associated with irritable bowel syndrome or that is idiopathic in nature. |
| DB08892 | Arbaclofen Placarbil | Investigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD. |
| DB08894 | Peginesatide | Peginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis |
| DB08900 | Teduglutide | A glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support. |
| DB08902 | Raxibacumab | A monoclonal antibody used in conjunction with an antibacterial regimen to treat patients with inhalational anthrax caused by Bacillus anthracis and for prophylaxis of inhalational anthrax when appropriate. |
| DB08904 | Certolizumab pegol | A tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis. |
| DB08935 | Obinutuzumab | An antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil. |
| DB08993 | Enviomycin | Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin. |
| DB09029 | Secukinumab | An immunomodulating agent and interleukin antagonist used to manage moderate to severe plaque psoriasis and active psoriatic arthritis or ankylosing spondylitis. |
| DB09033 | Vedolizumab | An integrin blocker and anti-inflammatory agent used to manage ulcerative colitis and Crohn's disease in adults with inadequate clinical response to immunomodulators. |
| DB09035 | Nivolumab | A PD-1 blocking antibody used to treat melanoma, non small-cell lung cancer, renal cell cancer, head and neck cancer, and Hodgkin lymphoma. |
| DB09036 | Siltuximab | An interleukin antagonist used to treat multicentric Castleman's disease (MCD) in patients who are HIV and HHV-8 negative. |
| DB09037 | Pembrolizumab | A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma. |
| DB09043 | Albiglutide | A GLP-1 agonist used to manage type 2 diabetes mellitus. |
| DB09045 | Dulaglutide | A GLP-1 agonist used to manage type 2 diabetes mellitus. |
| DB09046 | Metreleptin | A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy. |
| DB09052 | Blinatumomab | An antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). |
| DB09059 | Atosiban | An inhibitor of oxytocin and vasopressin used to delay imminent preterm birth in pregnant adult women displaying specific clinical observations. |
| DB09066 | Corifollitropin alfa | A FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program. |
| DB09067 | Corticorelin ovine triflutate | A synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. |
| DB09077 | Dinutuximab | An immunotherapeutic agent used in combination with other immunomodulating agents to treat high-risk neuroblastoma in pediatric patients who achieve at least a partial response to prior first-line multiagent, multimodality therapy. |
| DB09098 | Somatrem | A recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age. |
| DB09099 | Somatostatin | A naturally-occurring peptide hormone used for the symptomatic treatment of acute bleeding from esophageal varices. |
| DB09103 | Ancestim | A human stem cell factor used in combination with filgrastim during autologous peripheral blood progenitor cell (PBPC) transplantation to increase PBPC mobilization for improved collection. |
| DB09105 | Asfotase alfa | An enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP). |
| DB09107 | Methoxy polyethylene glycol-epoetin beta | A synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease. |
| DB09109 | Turoctocog alfa | An antihemorrhagic agent used for the treatment and prophylaxis of bleeding in patients of all ages with haemophilia A (congenital factor VIII deficiency). |
| DB09122 | Peginterferon beta-1a | An interferon beta used to treat relapsing forms of multiple sclerosis. |
| DB09126 | Chorionic Gonadotropin (Human) | A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women. |
| DB09137 | Technetium Tc-99m mebrofenin | A diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests. |
| DB09141 | Protamine sulfate | A blood factor used when the reversal of the anticoagulant effect of heparin is necessary and for the treatment of heparin overdose. |
| DB09142 | Sincalide | A diagnostic agent used to stimulate gallbladder contraction or pancreatic secretion during diagnostic tests, and accelerate fluoroscopy and x-ray examination of the intestinal tract. |
| DB09164 | Technetium Tc-99m disofenin | A radiopharmaceutical diagnostic agent used for hepatobiliary scans. |
| DB09218 | Clonixin | Indicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. |
| DB09221 | Polaprezinc | Peptic ulcer disease, dyspepsia . |
| DB09222 | Fibrinogen human | A hemostatic agent used for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia. |
| DB09230 | Azelnidipine | For the treatment of hypertension. |
| DB09264 | Idarucizumab | An antibody that binds dabigatran for the reversal of anticoagulant effects of dabigatran. |
| DB09265 | Lixisenatide | A GLP-1 receptor agonist used for the management of type 2 diabetes mellitus. |
| DB09272 | Eluxadoline | A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. |
| DB09292 | Sacubitril | A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. |
| DB09302 | Alirocumab | A PCSK9 inhibitor used as an adjunct to manage heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-cholesterol (LDL-C). |
| DB09303 | Evolocumab | A PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitor antibody used as an adjunct to LDL cholesterol reducing therapies, aiding in the prevention of cardiovascular events and cardiovascular revascularization procedures. |
| DB09331 | Daratumumab | A CD38-directed cytolytic antibody used alone or as an adjunct drug in the treatment of multiple myeloma. |
| DB09349 | Gastric intrinsic factor | Intrinsic factor is not currently available in any FDA or Health Canada approved products. However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic... |
| DB09357 | Dexpanthenol | An alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). |
| DB09393 | Amino acids | Mixture of amino acids ; used for parenteral nutrition in infants. |
| DB09421 | Protirelin | A synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland. |
| DB09477 | Enalaprilat | An antihypertensive agent used for the management of hypertension when oral therapy is not practical. |
| DB09527 | Secretin porcine | A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. |
| DB09559 | Necitumumab | A monoclonal antibody used to treat metastatic squamous non-small cell lung cancer. |
| DB09564 | Insulin degludec | A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. |
| DB09570 | Ixazomib | A monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already. |
| DB10516 | Casein | An extract from Casein used in allergy testing. |
| DB10789 | Bordetella pertussis pertactin antigen | Bordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis . |
| DB11091 | Hydrogen peroxide | A compound used as a disinfectant and sterilizer. |
| DB11095 | Desirudin | Indicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery. |
| DB11102 | N-acetyltyrosine | An amino acid used in total parenteral nutrition. |
| DB11142 | Selenomethionine | Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can... |
| DB11209 | Iron protein succinylate | Not Annotated |
| DB11210 | Ferrous bisglycinate | Ferrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and... |
| DB11242 | Gelatin | Gelatin is used for weight loss and for treating osteoarthritis, rheumatoid arthritis, and brittle bones (osteoporosis). Some people also use it for strengthening bones, joints, and fingernails. Gelatin is also... |
| DB11256 | Levomefolic acid | A folate supplement used to prevent neural tube defects in pregnancy or folate deficiency. |
| DB11296 | Prezatide | Commonly used in cosmetic products for the skin and hair . |
| DB11298 | Thioredoxin | Thioredoxin is a small dithiol protein and specific reductant for major allergenic proteins present in foods from animal and plant products. It is a 12-kD oxidoreductase enzyme encoded by TXN... |
| DB11300 | Thrombin | A coagulation factor used to stop bleeding during surgery. |
| DB11311 | Prothrombin | A coagulation factor used for emergency reversal of vitamin K antagonist therapy. |
| DB11312 | Protein C | A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis. |
| DB11330 | Factor IX Complex (Human) | A Factor IX complex used to prevent and treat bleeding episodes in hemophilia B or vitamin K antagonist therapy. |
| DB11332 | Sinapultide | A synthetic lung surfactant used to treat infant respiratory distress syndrome. |
| DB11364 | Pidotimod | For use as immunostimulant therapy for treatment of cell-mediated immunosuppression with respiratory or urinary infections . |
| DB11403 | Emodepside | Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the... |
| DB11467 | Thiostrepton | Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally... |
| DB11476 | Virginiamycin | Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent... |
| DB11510 | Deslorelin | Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones. |
| DB11567 | Insulin peglispro | Not Annotated |
| DB11569 | Ixekizumab | A monoclonal antibody used to treat moderate to severe plaque psoriasis. |
| DB11595 | Atezolizumab | A monoclonal antibody used to treat advanced or metastatic urothelial carcinoma with disease progression during or up to 12 months after platinum-containing chemotherapy. |
| DB11598 | Antithrombin III human | An alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency. |
| DB11611 | Lifitegrast | A medication used to treat dry eye disease. |
| DB11621 | Human Varicella-Zoster Immune Globulin | A solution of antibodies used for post exposure prophylaxis of varicella infections in high risk populations, as well as to reduce the severity of infections. |
| DB11624 | Epoetin delta | Epoetin Delta is an ingredient in the EMA-withdrawn product Dynepo. |
| DB11628 | Depreotide | Depreotide is an ingredient in the EMA-withdrawn product NeoSpect. |
| DB11631 | Eptotermin Alfa | A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin Alfa is an ingredient in... |
| DB11639 | Dibotermin alfa | indicated for the treatment of acute tibia fractures in adults, as an adjunct to standard care using open fracture reduction and intramedullary unreamed nail fixation [FDA Label].
indicated for single-level... |
| DB11646 | Conatumumab | Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others. |
| DB11653 | Bremelanotide | Bremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of... |
| DB11656 | Rebamipide | Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer. |
| DB11657 | Tabalumab | Tabalumab has been used in trials studying the treatment of Autoimmune Disease, Rheumatoid Arthritis, Kidney Failure, Chronic, Connective Tissue Disease, and Systemic Lupus Erythematosus, among others. |
| DB11668 | Rusalatide acetate | Chrysalin has been used in trials studying the treatment of Radius Fracture. |
| DB11680 | Ficlatuzumab | Ficlatuzumab has been used in trials studying the treatment of Acute Myeloid Leukemia, Non-small Cell Lung Cancer, Mullerian Mixed Tumor of Ovary, Relapsed Acute Myeloid Leukemia, and Refractory Acute Myeloid... |
| DB11682 | Daprodustat | Daprodustat has been used in trials studying the other, treatment, and basic science of Anaemia, Wound Healing, Tendon Injuries, Surgical Procedures, and Vascular Disease, Peripheral. |
| DB11685 | Figitumumab | Figitumumab has been used in trials studying the treatment of Sarcoma, Solid Tumor, Breast Cancer, Lung Neoplasms, and Advanced Cancer, among others. |
| DB11690 | Vonapanitase | Vonapanitase is under investigation for the treatment of Chronic Kidney Disease. |
| DB11695 | Carnosine | Carnosine has been investigated for the treatment of Gulf War Illness. |
| DB11696 | Racecadotril | Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis. |
| DB11700 | Setmelanotide | Setmelanotide has been investigated for the treatment of obesity. |
| DB11706 | Raxatrigine | Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression. |
| DB11709 | Acetyl hexapeptide-3 | Argireline has been used in trials studying the treatment of wrinkles. |
| DB11714 | Durvalumab | A monoclonal antibody used to treat urothelial carcinoma and locally advanced, unresectable non-small cell lung cancer. |
| DB11715 | Bapineuzumab | Bapineuzumab has been investigated for the treatment of Alzheimer's Disease. |
| DB11724 | Bombesin | Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and... |
| DB11746 | Onartuzumab | Onartuzumab has been used in trials studying the treatment of Neoplasms, Lung Cancer, Glioblastoma, Gastric Cancer, and Colorectal Cancer, among others. |
| DB11756 | Solanezumab | Solanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial. |
| DB11767 | Sarilumab | A monoclonal antibody used to treat moderate to severe rheumatoid arthritis who have responded poorly or are intolerant of other DMARDs. |
| DB11771 | Tremelimumab | Tremelimumab is under investigation for the treatment of Mesothelioma, Liver Cancer, Liver Neoplasms, Liver Cell Caricinoma, and HepatoCellular Carcinoma. Tremelimumab has been investigated in Part C: Malignant Mesothelioma and Part... |
| DB11776 | Brodalumab | A monoclonal antibody used to treat moderate to severe plaque psoriasis. |
| DB11777 | Cenderitide | Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall. |
| DB11781 | Tosedostat | Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others.
Tosedostat is an inhibitor of the... |
| DB11782 | Birinapant | Birinapant has been investigated for the treatment of Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML). |
| DB11788 | Neuropeptide Y | Neuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus. |
| DB11803 | Sirukumab | Sirukumab has been used in trials studying the treatment and basic science of Giant Cell Arteritis and Arthritis, Rheumatoid. |
| DB11808 | Faldaprevir | Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. |
| DB11815 | Tilarginine | Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow. |
| DB11821 | Danegaptide | Danegaptide has been investigated for the treatment of Focus of Study is STEMI. |
| DB11826 | Lampalizumab | Lampalizumab has been used in trials studying the treatment of Geographic Atrophy. |
| DB11834 | Guselkumab | A monoclonal antibody used to treat moderate to severe plaque psoriasis. |
| DB11840 | Dalotuzumab | Dalotuzumab has been investigated for the treatment of Breast Cancer, Non Small Cell Lung Cancer, and Metastatic Colorectal Cancer. |
| DB11842 | Angiotensin II | A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. |
| DB11849 | Emibetuzumab | Emibetuzumab has been used in trials studying the treatment of Advanced Cancer, Renal Cell Carcinoma, Hepatocellular Cancer, Gastric Adenocarcinoma, and Non-Small Cell Lung Cancer, among others. |
| DB11854 | Astodrimer | Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups. |
| DB11856 | Ligelizumab | Ligelizumab has been used in trials studying the basic science and treatment of Asthma, Allergy, Peanut Allergy, Allergic Asthma, and Atopic Dermatitis, among others. |
| DB11857 | Seribantumab | Seribantumab has been used in trials studying the treatment of NSCLC, Heregulin, Adenocarcinoma, Colorectal Cancer, and Solid Tumor Cancers, among others. |
| DB11862 | Landogrozumab | Landogrozumab has been used in trials studying the treatment of Advanced Cancer, Muscular Atrophy, and Pancreatic Cancer. |
| DB11865 | Brivanib alaninate | Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. |
| DB11866 | Romosozumab | A monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture, patients who are intolerant of other treatments, or patients who have failed other treatments. |
| DB11869 | Valspodar | Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others. |
| DB11876 | Alanyl glutamine | Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition). |
| DB11882 | BPC-157 | Bepecin is under investigation in clinical trial NCT02637284 (PCO-02 - Safety and Pharmacokinetics Trial). |
| DB11895 | Lenomorelin | Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others. |
| DB11906 | Acyline | Acyline has been investigated for the prevention and treatment of Hypogonadism and Contraception. |
| DB11915 | Valbenazine | A vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia. |
| DB11928 | Vosoritide | Vosoritide has been used in trials studying the treatment of Achondroplasia. |
| DB11945 | Avelumab | A monoclonal antibody used to treat metastatic merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma. |
| DB11955 | Avotermin | Juvista has been investigated for the treatment, prevention, and basic science of Scars, Keloid, and Cicatrix. |
| DB11956 | Delanzomib | Delanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin. |
| DB11958 | Brivanib | Brivanib is under investigation for the treatment of HepatoCellular Carcinoma. Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC). |
| DB11959 | Crenezumab | Crenezumab has been used in trials studying the treatment of Alzheimer's Disease. |
| DB11972 | Rilotumumab | Rilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others. |
| DB11975 | TAK-448 | TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism. |
| DB11976 | Anifrolumab | Anifrolumab has been investigated for the treatment of Scleroderma. |
| DB11981 | Elamipretide | Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy. |
| DB11988 | Ocrelizumab | A CD20 specific monoclonal antibody used to treat relapsing remitting multiple sclerosis. |
| DB11991 | Oprozomib | Oprozomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, Waldenstrom Macroglobulinemia, Advanced Hepatocellular Carcinoma, and Advanced Non-Central Nervous System (CNS) Malignancies. |
| DB11997 | Interleukin-7 | Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer. |
| DB12003 | Thymosin beta-4 | Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, and Dry Eye Syndrome, among others. |
| DB12005 | Nirogacestat | Nirogacestat has been used in trials studying the treatment of Breast Cancer, HIV Infection, Desmoid Tumors, Advanced Solid Tumors, and Aggressive Fibromatosis, among others. |
| DB12034 | Gantenerumab | Gantenerumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial. |
| DB12038 | Ulinastatin | Ulinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to Drug. |
| DB12042 | Ibodutant | Ibodutant has been used in trials studying the treatment of Irritable Bowel Syndrome and Irritable Bowel Syndrome With Diarrhea. |
| DB12044 | MK-0893 | MK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2. |
| DB12053 | Visilizumab | Visilizumab has been investigated for the treatment of Ulcerative Colitis. |
| DB12054 | BQ-123 | BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction. |
| DB12056 | Trebananib | Trebananib is under investigation for the treatment of Ovarian Cancer, Peritoneal Cancer, and Fallopian Tube Cancer. Trebananib has been investigated for the treatment of Cancer, Oncology, Carcinoma, Metastases, and Colon... |
| DB12075 | Nagrestipen | Nagrestipen has been used in trials studying the treatment of CANCER, Neoplasm, Metastasis, Radiation Oncology, and Neoplasm Metastasis. |
| DB12076 | Surotomycin | Surotomycin has been used in trials studying the treatment of Diarrhea and Clostridium Difficile Infection. |
| DB12088 | TT-232 | Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma). |
| DB12089 | Lorvotuzumab mertansine | Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others. |
| DB12090 | Patritumab | Patritumab has been used in trials studying the treatment of LUNG CANCER, Solid Tumors, Neoplasms by Site, Head and Neck Neoplasms, and Non-small Cell Lung Cancer, among others. |
| DB12095 | Telotristat ethyl | A tryptophan hydroxylase inhibitor used to treat carcinoid syndrome. |
| DB12099 | UK-396,082 | UK-396,082 has been used in trials studying the basic science of Safety, Phase 1, Toleration, Multiple Dose, and Pharmacokinetic. |
| DB12102 | Fulranumab | Fulranumab has been used in trials studying the treatment of Pain, Cystitis, Neuralgia, Joint Pain, and Arthralgia, among others. |
| DB12104 | Tarextumab | Tarextumab has been used in trials studying the treatment of Solid Tumors, Stage IV Pancreatic Cancer, and Stage IV Small Cell Lung Cancer. |
| DB12105 | Imagabalin | Imagabalin has been investigated in Generalized Anxiety Disorder. |
| DB12118 | Sotatercept | Sotatercept has been used in trials studying the supportive care and treatment of Anemia, Leukemia, Solid Tumors, Bladder Cancer, and multiple myeloma, among others. |
| DB12119 | Gevokizumab | Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine... |
| DB12126 | Bradykinin | Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2. |
| DB12132 | Vanutide cridificar | Vanutide cridificar has been investigated for the treatment of Alzheimer Disease. |
| DB12139 | Alisporivir | Alisporivir has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C. |
| DB12142 | Duligotuzumab | Duligotuzumab has been used in trials studying the treatment of Neoplasms, Colorectal Cancer, Head and Neck Cancer, and Epithelial Tumors, Malignant. |
| DB12146 | Rigosertib | Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others. |
| DB12159 | Dupilumab | A monoclonal antibody used to treat moderate to severe atopic dermatitis, asthma, and nasal polyps accompanied by chronic rhinosinusitis in adolescents and adults. |
| DB12160 | Bucillamine | Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis. |
| DB12169 | Tralokinumab | Tralokinumab is under investigation for the treatment of Alopecia Areata. Tralokinumab has been investigated for the treatment of Asthma. |
| DB12182 | Binetrakin | Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others. |
| DB12189 | Etrolizumab | Etrolizumab has been used in trials studying the treatment of Crohn Disease and Ulcerative Colitis. |
| DB12205 | Ganitumab | Ganitumab has been used in trials studying the treatment of Colon Cancer, Rectal Cancer, Breast Cancer, Breast Tumors, and Breast Neoplasms, among others. |
| DB12213 | Etaracizumab | Etaracizumab has been investigated for the treatment of Psoriasis, Renal Cell Carcinoma, Stage IV Renal Cell Cancer, Recurrent Renal Cell Cancer, and Stage III Renal Cell Cancer. |
| DB12224 | Oxothiazolidinecarboxylic acid | Procysteine has been used in trials studying the treatment of HIV Infections. |
| DB12240 | Polatuzumab vedotin | This medication is indicated to treat adults with relapsed or refractory diffuse large B-cell lymphoma in combination with bendamustine and rituximab that has returned of progressed after 2 or more... |
| DB12246 | Inclacumab | Inclacumab has been used in trials studying the treatment and prevention of Myocardial Infarction, Peripheral Arterial Disease (PAD), and Coronary Heart Disease, Graft Occlusion, Vascular. |
| DB12250 | Cixutumumab | Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate.
Cixutumumab is a highly specific recombinant... |
| DB12261 | Ascrinvacumab | Ascrinvacumab has been used in trials studying the treatment and basic science of Neoplasms, Advanced Solid Tumors, Carcinoma, Hepatocellular, and Malignant Pleural Mesothelioma. |
| DB12271 | ORE-1001 | ORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor. |
| DB12274 | Aducanumab | Aducanumab has been used in trials studying the treatment of Alzheimer's Disease. |
| DB12279 | OBP-801 | OBP-801 has been used in trials studying the treatment of Solid Tumor. |
| DB12292 | Barusiban | Barusiban has been used in trials studying the treatment of Infertility and In Vitro Fertilisation (IVF) Treatment. |
| DB12304 | Entolimod | Entolimod has been used in trials studying the treatment of Mucositis, Tongue Cancer, Colorectal Cancer, Stage IVA Verrucous Carcinoma of the Larynx, and Stage IVB Verrucous Carcinoma of the Larynx,... |
| DB12330 | Blisibimod | Blisibimod has been used in trials studying the treatment of IgA Nephropathy, Microscopic Polyangiitis, Systemic Lupus Erythematosus, and Granulomatosis With Polyangiitis. |
| DB12335 | Tanezumab | Tanezumab has been investigated for the treatment of Osteoarthritis, Knee and Neuralgia, Postherpetic. |
| DB12349 | Dulanermin | Dulanermin has been used in trials studying the treatment of Colorectal Cancer, Non-Hodgkin's Lymphoma, and Metastatic Colorectal Cancer. |
| DB12363 | Dusigitumab | Dusigitumab has been used in trials studying the treatment of Cancer, Advanced Solid Malignancies, Unresectable or Metastatic Hepatocellular Carcinoma (HCC), and Hormone-sensitive, HER-2 Negative Metastatic Breast Cancer. |
| DB12370 | Ipamorelin | Ipamorelin has been investigated for the treatment of Ileus. |
| DB12373 | Isunakinra | Isunakinra has been investigated for the treatment of Dry Eye and Allergic Conjunctivitis (AC). |
| DB12396 | Fresolimumab | Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis. |
| DB12409 | Vatreptacog alfa | Vatreptacog Alfa (Activated) has been used in trials studying the treatment of Haemophilia B, Haemophilia A, Congenital Bleeding Disorder, Haemophilia A With Inhibitors, and Haemophilia B With Inhibitors. |
| DB12431 | Muplestim | Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in... |
| DB12444 | Theanine | Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD). |
| DB12451 | SCY-635 | SCY-635 has been investigated for the treatment of Chronic Hepatitis C and Hepatitis C Infection. |
| DB12456 | Bococizumab | Bococizumab has been used in trials studying the treatment and prevention of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, and Heterozygous Familial Hypercholesterolemia. |
| DB12460 | Conbercept | Conbercept has been investigated for the basic science of Age-related Macular Degeneration. |
| DB12463 | Semagacestat | Semagacestat has been used in trials studying the treatment of Alzheimer Disease. |
| DB12486 | Elobixibat | Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. |
| DB12489 | Mirvetuximab Soravtansine | Mirvetuximab Soravtansine has been used in trials studying the treatment of Ovarian cancer, Endometrial Cancer, Fallopian tube cancer, Epithelial Ovarian Cancer, and Primary Peritoneal Cancer, among others. |
| DB12490 | Forigerimod | Forigerimod is under investigation for the treatment of Lupus Erythematosus, Systemic. |
| DB12493 | PD-217014 | PD-217,014 has been used in trials studying the treatment of Pain and Irritable Bowel Syndrome. |
| DB12495 | Selepressin | Selepressin has been used in trials studying the treatment of Septic Shock. |
| DB12498 | Mogamulizumab | A monoclonal antibody used to treat relapsed or refractory mycosis fungoides or Sézary syndrome after attempting one other therapy. |
| DB12514 | Iofolastat I-123 | Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer). |
| DB12519 | Sarcosine | Sarcosine has been investigated for the treatment of Schizophrenia. |
| DB12525 | Molgramostim | Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis. |
| DB12530 | Inebilizumab | Inebilizumab has been used in trials studying the treatment of Blood Cancer, B-cell Malignancies, Advanced B Cell Malignancies, Chronic Lymphocytic Leukemia (CLL), and Diffuse Large B-Cell Lymphoma (DLBCL). |
| DB12534 | Mavrilimumab | Mavrilimumab has been investigated for the treatment of Rheumatoid Arthritis. |
| DB12538 | Nepadutant | Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional Gastrointestinal Disorders. |
| DB12560 | Blosozumab | Blosozumab has been used in trials studying the basic science and treatment of Osteoporosis and Osteoporosis, Postmenopausal. |
| DB12566 | Decernotinib | Decernotinib has been used in trials studying the treatment of Drug Interactions and Rheumatoid Arthritis. |
| DB12568 | Tecemotide | Tecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung. |
| DB12584 | Bimagrumab | Bimagrumab has been used in trials studying the treatment and supportive care of Sarcopenia, Skeletal Muscle, Mechanical Ventilation, Sporadic Inclusion Body Myositis, and Sporadic Inclusion Body Myositis (sIBM), among others. |
| DB12589 | Dacetuzumab | Investigated for use/treatment in lymphoma (non-hodgkin's) and multiple myeloma. |
| DB12602 | Pentetreotide | Pentetreotide has been used in trials studying the diagnostic of cushing syndrome. |
| DB12609 | Tovetumab | Tovetumab has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Advanced Solid Malignancies. |
| DB12613 | Davunetide | Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive Supranuclear Palsy, Predicted Tauopathies, Including, Corticobasal Degeneration Syndrome, and Frontotemporal Dementia With Parkinsonism Linked to Chromosome... |
| DB12616 | Sprifermin | Sprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury of Knee. |
| DB12620 | Nerve Growth Factor | Nerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development, among others. |
| DB12629 | 3,5-diiodothyropropionic acid | DITPA has been investigated in Congestive Heart Failure. |
| DB12648 | Nona-arginine | Nona-arginine is under investigation in clinical trial NCT00264706 (PolyArginine Treated vEiN grafTs (PATENT)). |
| DB12652 | Endothelin-1 | Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin). |
| DB12677 | Soblidotin | Soblidotin has been used in trials studying the treatment of Sarcoma, Lung Cancer, and Unspecified Adult Solid Tumor, Protocol Specific. |
| DB12678 | Relamorelin | Relamorelin has been investigated for the treatment and basic science of Gastroparesis, Gastric Motility, Diabetes Mellitus, Parkinson's Disease, and Chronic Constipation, among others. |
| DB12684 | Aviscumine | Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy). |
| DB12697 | Methylselenocysteine | Methylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease. |
| DB12698 | Ibalizumab | A CD4-specific antibody used to treat HIV infections. |
| DB12699 | Balugrastim | Balugrastim has been used in trials studying the treatment of Solid Tumors. |
| DB12701 | Intetumumab | Intetumumab has been used in trials studying the treatment of Melanoma. |
| DB12711 | LTX-109 | LTX-109 has been investigated for the treatment of Atopic Dermatitis, Mild Eczema/Dermatoses, and Gram-positive, Skin Infections. |
| DB12718 | Carlumab | Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. |
| DB12726 | Monteplase | Monteplase has been used in trials studying the treatment of Pulmonary Embolism. |
| DB12730 | Dolastatin 10 | Dolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others. |
| DB12732 | Firategrast | Firategrast has been used in trials studying the treatment of Multiple Sclerosis. |
| DB12734 | Demcizumab | Demcizumab is under investigation for the treatment of Nonsquamous Nonsmall Cell Neoplasm of Lung. |
| DB12738 | Tiplimotide | Tiplimotide has been used in trials studying the treatment of Multiple Sclerosis. |
| DB12748 | LTX-315 | LTX-315 has been used in trials studying the treatment of Cancer, Lymphoma, Melanoma, Carcinoma, and Breast Cancer, among others. |
| DB12750 | N-omega-nitro-L-arginine methyl ester | L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury. |
| DB12755 | Zoptarelin doxorubicin | Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. |
| DB12762 | Rabacfosadine | Rabacfosadine has been used in trials studying the treatment of Multiple Myeloma, Non-Hodgkin's Lymphoma, and Chronic Lymphocytic Leukemia. |
| DB12775 | Abituzumab | Abituzumab has been used in trials studying the treatment of Prostate Cancer Metastatic. |
| DB12777 | Somatoprim | Somatoprim is under investigation for the treatment of Acromegaly. |
| DB12795 | CMX-2043 | CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. |
| DB12807 | Naptumomab Estafenatox | Naptumomab Estafenatox has been used in trials studying the treatment of Pancreatic Cancer, Renal Cell Carcinoma, and Non-Small-Cell Lung Carcinoma. |
| DB12815 | Crotedumab | Crotedumab has been used in trials studying the treatment of Diabetes Mellitus, Type 2. |
| DB12820 | Concizumab | Concizumab has been used in trials studying the treatment of Haemophilia A and Congenital Bleeding Disorder. |
| DB12822 | Pancreatic Polypeptide | Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1. |
| DB12826 | Depatuxizumab | Depatuxizumab has been used in trials studying the treatment and diagnostic of Adenocarcinoma and Advanced Solid Tumors. |
| DB12827 | Indoximod | Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others. |
| DB12835 | Olipudase alfa | Olipudase alfa has been used in trials studying the treatment of Sphingomyelin Lipidosis and Human Acid Sphingomyelinase Deficiency. |
| DB12844 | Rontalizumab | Rontalizumab has been used in trials studying the treatment of Systemic Lupus Erythematosus. |
| DB12845 | Amatuximab | Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. |
| DB12849 | Clazakizumab | Clazakizumab has been used in trials studying the treatment of Rheumatoid Arthritis. |
| DB12863 | Sivelestat | Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult. |
| DB12865 | Etelcalcetide | A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in patients with chronic kidney disease who require hemodialysis. |
| DB12870 | Buthionine Sulfoximine | Buthionine Sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin). |
| DB12876 | GS-9256 | GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection. |
| DB12878 | AV-101 | AV-101 has been used in trials studying the treatment of Neuropathic Pain. |
| DB12880 | Interleukin-10 | Interleukin-10 has been used in trials studying the prevention and treatment of Vasculitis, Pancreatitis, Bile Duct Diseases, Pancreatic Diseases, and Gallbladder Diseases, among others. |
| DB12882 | Ombrabulin | Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms, Malignant, and Advanced Solid Tumors, among others. |
| DB12891 | Ozanezumab | Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting. |
| DB12893 | Sacituzumab govitecan | Sacituzumab govitecan has been used in trials studying the treatment of Breast Cancer, Cervical Cancer, Renal Cell Cancer, Colorectal Cancer, and Esophageal Cancer, among others. |
| DB12909 | Factor XIII (human) | A purified form of Factor XIII that is used to prevent and treat surgical bleeding in patients with a Factor XIII deficiency. |
| DB12938 | Isoxaflutole | Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder. |
| DB12943 | Milatuzumab | Milatuzumab has been used in trials studying the treatment of Lupus Nephritis, Multiple Myeloma (MM), GVHD (Acute or Chronic), Myelodysplastic Syndrome, and Chronic Lymphocytic Leukemia, among others. |
| DB12951 | Pivagabine | Pivagabine has been used in trials studying the treatment of Stress and Anxiety. |
| DB12976 | Robatumumab | Robatumumab has been used in trials studying the treatment of Osteosarcoma, Sarcoma, Ewing's, and Peripheral Neuroectodermal Tumor. |
| DB12992 | Bleomycin A6 | Bleomycin A6 has been used in trials studying the treatment of Squamous Cell Lung Cancer. |
| DB13006 | Cibinetide | Cibinetide has been used in trials studying the basic science of Depression. |
| DB13033 | Urocortin-2 | Urocortin 2 has been investigated for the basic science of Heart Failure and Cardiovascular Disease. |
| DB13045 | Racotumomab | Racotumomab has been used in trials studying the treatment of Glioma, Wilm's Tumor, Neuroblastoma, Retinoblastoma, and Ewing's Sarcoma. |
| DB13067 | Rotigaptide | Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease. |
| DB13068 | 9-(N-methyl-L-isoleucine)-cyclosporin A | 9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse. |
| DB13074 | Macimorelin | A medication used to treat adult growth hormone deficiency. |
| DB13091 | Tiropramide | Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome). |
| DB13127 | Olokizumab | Olokizumab has been used in trials studying the treatment of Crohn's Disease. |
| DB13133 | Von Willebrand Factor Human | A complex of von Willebrand Factor and Factor VIII used to treat bleeding episodes in von Willebrand disease. |
| DB13144 | Lenograstim | The drug is used to reduce the risk of life-threatening infection in patients with neutropenia, particularly after cytotoxic chemotherapy.
Lenograstim is indicated as a treatment to reduce the duration of... |
| DB13148 | Coagulation factor X human | A coagulation factor used to treat Factor X deficiency to control bleeding. |
| DB13149 | Protein S human | A medication used for emergency reversal of coagulation factor deficiency in vitamin K antagonist therapy. |
| DB13150 | Coagulation factor VII human | A coagulation factor used to treat bleeding disorders such as hemophilia and Glanzmann's thrombasthenia. |
| DB13166 | Zofenopril | Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor. |
| DB13191 | Phosphocreatine | Phosphocreatine is a naturally occuring substance that is found predominantly in the skeletal muscles of vertebrates. Its primary utility within the body is to serve in the maintanence and recycling... |
| DB13192 | Antihemophilic factor human | A Factor VIII replacement therapy used to treat hemophilia A. |
| DB13197 | Kallidinogenase | Not Annotated |
| DB13200 | Lipegfilgrastim | A medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy. |
| DB13201 | Trenonacog alfa | Human coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells. |
| DB13207 | Arginine glutamate | Not Annotated |
| DB13226 | Acetylleucine | Used for treating vestibular-related imbalance and vertigo. |
| DB13233 | Alaproclate | Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity... |
| DB13298 | Alsactide | Not Annotated |
| DB13299 | Sulglicotide | Not Annotated |
| DB13313 | Melevodopa | Not Annotated |
| DB13363 | Oxaceprol | Not Annotated |
| DB13375 | Edrecolomab | Not Annotated |
| DB13431 | Proglumide | Not Annotated |
| DB13447 | Prethcamide | Not Annotated |
| DB13455 | Phenibut | Not Annotated |
| DB13464 | Ornipressin | Not Annotated |
| DB13503 | Tyrothricin | A topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections. |
| DB13517 | Angiotensinamide | Not Annotated |
| DB13535 | Nebacumab | Not Annotated |
| DB13590 | Calcium pangamate | Not Annotated |
| DB13615 | Mifamurtide | A muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection. |
| DB13626 | Aluminium glycinate | Not Annotated |
| DB13646 | Saruplase | Not Annotated |
| DB13704 | Pristinamycin | Not Annotated |
| DB13738 | Camylofin | Not Annotated |
| DB13742 | Elcatonin | Not Annotated |
| DB13798 | Demoxytocin | Not Annotated |
| DB13809 | Paclitaxel poliglumex | Not Annotated |
| DB13864 | Hemoglobin crosfumaril | Hemoglobin in which the alpha-subunit are cross-linked intramolecularly. |
| DB13886 | Human cytomegalovirus immune globulin | A solution of immune globulin G against cytomegalovirus used to prevent transmission of cytomegalovirus after organ transplants. |
| DB13923 | Emicizumab | An antibody against Factor IXa and Factor X used to treat hemophilia A. |
| DB13928 | Semaglutide | A glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus. |
| DB13931 | Netarsudil | A rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension. |
| DB13933 | Nonacog beta pegol | A recombinant coagulation Factor IX derivative used to treat hemophilia B. |
| DB13968 | Plasma protein fraction (human) | A plasma protein solution used to treat coagulation factor deficiencies, reverse anticoagulant effects, and shock from a loss of plasma fluids, and is also used in plasma exchange procedures. |
| DB13972 | Racemethionine | A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers. |
| DB13976 | Sulesomab | Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes. |
| DB13979 | Besilesomab | A monoclonal antibody bound to technetium-99 used to find infection and inflammation in patients with suspected osteomyelitis. |
| DB13985 | Lutetium Lu 177 dotatate | A radiolabeled somatostatin analog used to treat somatostatin receptor positive gastroenteropancreatic neuroendocrine tumors. |
| DB13999 | Moroctocog alfa | A recombinant Factor VIII used to treat hemophilia A to control bleeding. |
| DB14004 | Tildrakizumab | An interleukin-23 antagonist used to treat moderate to severe plaque psoriasis. |
| DB14027 | Taspoglutide | Taspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche. In September 2010 Roche halted... |
| DB14028 | Nordazepam | An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam. |
| DB14039 | Erenumab | A calcitonin-gene related peptide antagonist used to prevent migraines. |
| DB14041 | Fremanezumab | A humanized monoclonal antibody directed against human calcitonin-gene related peptide to prevent migraines. |
| DB14044 | Hopantenic acid | Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal... |
| DB05624 | Teverelix | Investigated for use/treatment in benign prostatic hyperplasia, endometriosis, and prostate cancer. |
| DB14057 | Valinomycin | A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately... |
| DB14058 | Basifungin | Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , . |
| DB14072 | Reversin 121 | Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. |
| DB14076 | Interleukin-1 alpha, human recombinant | Not Annotated |
| DB14103 | Methionine sulfoximine | Not Annotated |
| DB14127 | Sacubitrilat | A metabolite of LCZ696 with neprilysin inhibitory activity. |
| DB14131 | Basic Fibroblast Growth Factor | Basic Fibroblast Growth Factor is not currently approved for any FDA or Health Canada approved indications. |
| DB14145 | Nepidermin | Not Annotated |
| DB14207 | Fosinoprilat | Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. |
| DB14211 | Fanolesomab | An anti-SSEA-1 monoclonal antibody used for imaging of the appendix and to diagnose appendicitis. |
| DB14218 | Telotristat | A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat. |
| DB14472 | Insulin-like growth factor II | The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth... |
| DB14473 | Beroctocog alfa | Beroctocog alfa is indicated for the prevention and control of bleeding in patients with hemophilia A or acquired Factor VIII (FVIII) deficiency. It is also indicated for surgical/invasive procedures in... |
| DB14480 | Acetylcysteine amide | Not Available |
| DB14493 | Zinc glycinate | Glycoprotein marker of gastrointestinal cancer. |
| DB09532 | Secretin human | A secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts. |
| DB14562 | Andexanet alfa | A recombinant Factor Xa used to reverse anticoagulation caused by rivaroxaban and apixaban. |
| DB14597 | Lanadelumab | A plasma kallikrein inhibitor used to treat attacks of hereditary angioedema. |
| DB09329 | Antihemophilic Factor (Recombinant), PEGylated | For the management of hemophilia A (congenital factor VIII deficiency) [FDA label], .
This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)... |
| DB14642 | Lypressin | Not Annotated |
| DB12688 | Moxetumomab Pasudotox | A CD22-specific antibody conjugated to a truncated exotoxin used to treat relapsed or refractory hairy cell leukemia in patients who have already been treated with a purine nucleoside analog and one other treatment. |
| DB08766 | Zofenoprilat | Not Available |
| DB06111 | AB192 | Investigated for use/treatment in diabetes mellitus type 2. |
| DB14042 | Galcanezumab | A calcitonin-gene related peptide antagonist used to prevent migraines and treat cluster headaches. |
| DB07558 | acetylleucyl-leucyl-norleucinal | Not Available |
| DB00129 | Ornithine | An amino acid commonly found as a component in total parenteral nutrition. |
| DB01752 | S-adenosyl-L-homocysteine | 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions. |
| DB02458 | S-(2,4-dinitrophenyl)glutathione | Not Available |
| DB02530 | gamma-Aminobutyric acid | The most common inhibitory neurotransmitter in the central nervous system. |
| DB02691 | Glycocholic acid | The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed. |
| DB02751 | Glycocyamine | Not Available |
| DB03310 | Glutathione disulfide | An ingredient of ophthalmic irrigation solutions used during ophthalmological procedures. |
| DB03604 | Tiratricol | A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. |
| DB03810 | 3-Methylglutamic acid | Not Available |
| DB11693 | Voclosporin | Voclosporin is a novel cyclosporine analog and immunosuppressive compound currently being investigated for the treatment of psoriasis and for the prevention of organ rejection in kidney transplant patients. All studies... |
| DB11835 | Indium In-111 pentetreotide | Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome. |
| DB11914 | Lebrikizumab | Lebrikizumab has been used in trials studying the treatment of Asthma, Allergic Asthma, Atopic Dermatitis, Idiopathic Pulmonary Fibrosis, and COPD, Chronic Obstructive Pulmonary Disease. |
| DB12023 | Benralizumab | A monoclonal antibody used to treat eosinophilic asthma. |
| DB12202 | Zalutumumab | Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell... |
| DB12520 | Plozalizumab | Plozalizumab has been investigated for the treatment of Atherosclerosis. Plozalizumab, a novel humanized monoclonal antibody, specifically targets CCR2 chemokine receptors found on the surface of certain white blood cells including... |
| DB12581 | Ozarelix | Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy, and Benign Prostatic Hyperplasia (BPH). |
| DB12664 | Indantadol | Indantadol has been used in trials studying the treatment of Cough and Diabetic Peripheral Neuropathic Pain. |
| DB12773 | Sifalimumab | Sifalimumab is a fully human monoclonal antibody targeting interferon-alpha. The levels of interferon-alpha are elevated in many patients with active systemic lupus erythematosus (SLE, or lupus) and other autoimmune disorders,... |
| DB13170 | Plecanatide | A laxative used to treat chronic idiopathic constipation and IBS with constipation. |
| DB14724 | Emapalumab | An interferon gamma blocking antibody used to treat primary hemophagocytic lymphohistiocytosis. |
| DB05004 | Peptide YY (3-36) | Investigated for use/treatment in metabolic disease and obesity. |
| DB14731 | Tagraxofusp | A CD123-directed cytotoxin used to treat plasmacytoid dendritic cell neoplasm. |
| DB00091 | Cyclosporine | A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. |
| DB06651 | DiaPep 277 | Investigated for use/treatment in diabetes mellitus type 1, autoimmune diseases, and diabetes mellitus type 2. |
| DB14738 | Turoctocog alfa pegol | Turoctocog alfa pegol (N8-GP) is indicated for use in adults and children of all ages with hemophilia A (congenital factor VIII deficiency) for routine prophylaxis in reducing the frequency of... |
| DB14741 | Luteinizing hormone | Not Annotated |
| DB00781 | Polymyxin B | A polymyxin antibiotic used to treat a wide variety of infections in the body. |
| DB02446 | Glutamine hydroxamate | Not Available |
| DB03314 | 5-fluorotryptophan | 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. |
| DB06400 | Vitespen | Investigated for use/treatment in kidney cancer, melanoma, renal cell carcinoma, lymphoma (unspecified), colorectal cancer, and brain cancer. |
| DB05304 | Girentuximab | Investigated for use/treatment in gall bladder cancer and renal cell carcinoma. |
| DB14760 | Narlaprevir | Not Annotated |
| DB14761 | Remdesivir | Not Annotated |
| DB14762 | Risankizumab | An interleukin-23 antagonist used to treat moderate to severe plaque psoriasis. |
| DB05386 | Regramostim | Investigated for use/treatment in adverse effects (chemotherapy) and bone marrow transplant. |
| DB05875 | Sar9, Met (O2)11-Substance P | Investigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection. |
| DB14767 | Peginterferon lambda-1a | Peginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C). |
| DB14786 | Nerofe | Nerofe is under investigation in clinical trial NCT03059615 (A Phase 2a, Open-Label, Two Stage Study of Nerofe or Nerofe With Doxorubicin in Subjects With AML or MDS). |
| DB14806 | Avexitide | Avexitide is under investigation in clinical trial NCT02996812 (Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia). |
| DB14807 | Demplatin pegraglumer | Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer). |
| DB14809 | Anetumab ravtansine | Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer). |
| DB14811 | Isatuximab | Isatuximab is under investigation in clinical trial NCT02514668 (A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Isatuximab in Patients With Multiple Myeloma). |
| DB14812 | Procalcitonin | Procalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD). |
| DB14824 | Icrucumab | Icrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer). |
| DB14852 | PRM-151 | PRM-151 is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis). |
| DB14865 | Human interleukin-2 | Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL). |
| DB14877 | Lintuzumab | Lintuzumab is under investigation in clinical trial NCT00016159 (Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia). |
| DB14880 | Uteroglobin | Uteroglobin is under investigation in clinical trial NCT01473264 (Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS)). |
| DB14891 | Vobarilizumab | Vobarilizumab is under investigation in clinical trial NCT02101073 (ALX-0061 Phase I Bioavailability Study in Healthy Volunteers). |
| DB14905 | Emactuzumab | Emactuzumab is under investigation in clinical trial NCT01494688 (A Study of RO5509554 as Monotherapy and in Combination With Paclitaxel in Participants With Advanced Solid Tumors). |
| DB14907 | Bevacizumab zirconium Zr-89 | Bevacizumab zirconium Zr-89 is under investigation in clinical trial NCT01338090 (89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors). |
| DB14908 | Refanezumab | Refanezumab is under investigation in clinical trial NCT00833989 (Safety Escalating Repeat IV, in Stroke Patients). |
| DB14940 | Aspartyl-alanyl-diketopiperazine | Aspartyl-alanyl-diketopiperazine is under investigation in clinical trial NCT03349645 (An Open Label Extension Study to Assess the Safety of Long-Term Treatment With Ampion for Severe OA of the Knee). |
| DB14941 | BMS-817399 | BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis). |
| DB14952 | Pamrevlumab | Pamrevlumab is under investigation in clinical trial NCT00913393 (Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapy). |
| DB14956 | Davalintide | Davalintide is under investigation in clinical trial NCT00785408 (Study to Examine Safety, Tolerability and Effect on Body Weight of Subcutaneous AC2307 in Obese or Overweight Subjects). |
| DB14988 | Dalantercept | Dalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma). |
| DB14997 | Pateclizumab | Pateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in... |
| DB14999 | Human interferon beta | Human interferon beta is under investigation in clinical trial NCT02584829 (Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic... |
| DB15015 | Recombinant CD40-ligand | Recombinant CD40-ligand is under investigation in clinical trial NCT00053391 (Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma). |
| DB15022 | Apomab | Apomab is under investigation in clinical trial NCT00851136 (A Study of PRO95780 Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced, Recurrent, and... |
| DB15045 | Ipafricept | Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors). |
| DB15076 | Abrilumab | Abrilumab is under investigation in clinical trial NCT01290042 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181.). |
| DB15084 | GS-9191 | GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts). |
| DB15093 | Somapacitan | Somapacitan is under investigation in clinical trial NCT01706783 (A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily... |
| DB15094 | Anfibatide | Anfibatide is under investigation in clinical trial NCT01585259 (Anfibatide Phase Ib-IIa Clinical Trial). |
| DB15095 | Leridistim | Leridistim is under investigation in clinical trial NCT00004215 (Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia). |
| DB15101 | Tigatuzumab | Tigatuzumab is under investigation in clinical trial NCT00991796 (CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)). |
| DB15112 | Somatropin pegol | Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083). |
| DB15113 | Utomilumab | Utomilumab is under investigation in clinical trial NCT03318900 (T Cell Immunotherapy for Advanced Ovarian Cancer). |
| DB15118 | Zolbetuximab | Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer). |
| DB15131 | Interferon alfa-2c | Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma). |
| DB15135 | Ponezumab | Ponezumab is under investigation in clinical trial NCT00607308 (A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease). |
| DB15150 | Fibronectin | Fibronectin is under investigation in clinical trial NCT01812239 (Vaginal Progesterone in Twins With Short Cervix). |
| DB15160 | Asunercept | Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme). |
| DB15166 | Albuvirtide | Albuvirtide is under investigation in clinical trial NCT03719664 (Albuvirtide and 3BNC117 as Long-Acting Maintenance Therapy in Virologically Suppressed Subjects). |
| DB15172 | Suvratoxumab | Suvratoxumab is under investigation in clinical trial NCT02296320 (Study of the Efficacy and Safety of MEDI4893). |
| DB15217 | Gastric inhibitory polypeptide | Gastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea). |
| DB15225 | Mitazalimab | Mitazalimab is under investigation in clinical trial NCT02379741 (ADC-1013 First-in-Human Study). |
| DB15228 | Avidin | Avidin is under investigation in clinical trial NCT00345618 (Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach). |
| DB15231 | Brimapitide | Brimapitide is under investigation in clinical trial NCT01570205 (Safety, Tolerability and PK of a Single iv Infusion of 10, 40, and 80 µg/kg XG-102 Administered to Healthy Volunteers). |
| DB15251 | Antipain | Antipain is under investigation in clinical trial NCT02891785 (Praxis Evaluation of a Pain Self-management Support Intervention for Oncology Patients: A Stepped Wedge Design Study). |
| DB15253 | Bleselumab | Bleselumab is under investigation in clinical trial NCT02921789 (Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant... |
| DB15263 | Thyrotropin | Thyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human Myometrium). |
| DB15272 | Edratide | Edratide is under investigation in clinical trial NCT00203151 (A Study to Evaluate the Tolerability, Safety and Effectiveness of Edratide in the Treatment of Lupus). |
| DB15301 | Bevifimod | Bevifimod is under investigation in clinical trial NCT01749787 (Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis). |
| DB15313 | DAS-181 | DAS-181 is under investigation in clinical trial NCT00527865 (Single Dose Escalating Study of DAS181 in Adults). |
| DB15319 | VM4-037 | VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037). |
| DB15336 | Valanafusp alfa | Valanafusp alfa is under investigation in clinical trial NCT03071341 (Extension Study Evaluating Long Term Safety and Activity of AGT-181 in Children With MPS I). |
| DB15355 | PL-3994 | PL-3994 is under investigation in clinical trial NCT01304628 (Cross-Over Study of Subcutaneous Study Drug for the Treatment of Patients With Mild to Moderate Asthma). |
| DB15363 | Istiratumab | Istiratumab is under investigation in clinical trial NCT02399137 (A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer). |
| DB15383 | Pidilizumab | Pidilizumab is under investigation in clinical trial NCT01952769 (Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma). |
| DB15386 | ALT-801 | ALT-801 is under investigation in clinical trial NCT01478074 (ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia). |
| DB15397 | GMA-161 | GMA-161 is under investigation in clinical trial NCT00244257 (Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP)). |
| DB15402 | Tucotuzumab celmoleukin | Tucotuzumab celmoleukin is under investigation in clinical trial NCT00016237 (Interleukin-2 Combined With Monoclonal Antibody Therapy in Treating Patients With Kidney, Bladder, or Lung Cancer That Has Not Responded to Previous... |
| DB15409 | Ladiratuzumab vedotin | Ladiratuzumab vedotin is under investigation in clinical trial NCT01969643 (A Safety Study of SGN-LIV1A in Breast Cancer Patients). |
| DB15415 | Tomaralimab | Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function). |
| DB15428 | Vesencumab | Vesencumab is under investigation in clinical trial NCT00747734 (A Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors). |
| DB15432 | Pinatuzumab vedotin | Pinatuzumab vedotin is under investigation in clinical trial NCT01691898 (A Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined With Rituximab or Obinutuzumab in Participants With... |
| DB15441 | Lulizumab pegol | Lulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome). |
| DB15443 | Lorukafusp alfa | Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma). |
| DB15453 | Naratuximab emtansine | Naratuximab emtansine is under investigation in clinical trial NCT01534715 (IMGN529 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia). |
| DB15458 | Norleucine | Norleucine is under investigation in clinical trial NCT00081952 (Amino Acid Therapy for Hot Flashes in Postmenopausal Women). |
| DB05433 | rGLP-1 | Investigated for use/treatment in congestive heart failure and diabetes mellitus type 2. |
| DB05916 | CT-011 | Investigated for use/treatment in cancer/tumors (unspecified). |
| DB05950 | Contulakin-G | Investigated for use/treatment in pain (acute or chronic). |
| DB06305 | Sonepcizumab | Investigated for use/treatment in solid tumors. |
| DB06402 | Telavancin | An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia. |
| DB06610 | Omiganan | Investigated for use/treatment in bacterial infection and rosacea. |
| DB08898 | Glucarpidase | A carboxypeptidase enzyme used to treat toxic plasma methotrexate concentrations by providing an alternate elimination pathway for methotrexate in patients who have impaired renal function. |
| DB08965 | Fusafungine | Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections. |
| DB11204 | Panthenol | An ingredient used in skin, hair care, and nutritional products but is not an approved medication. |
| DB11572 | Thrombin alfa | A platelet activating factor used to treat minor bleeding. |
| DB11580 | Ravulizumab | A monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria. |
| DB11608 | Eftrenonacog alfa | A recombinant Factor IX used to treat and prevent bleeding in hemophilia B. |
| DB11720 | Angiotensin 1-7 | TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. |
| DB11727 | Endostar | Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer. |
| DB11731 | Depatuxizumab mafodotin | No approved indication. |
| DB11801 | Rapastinel | Rapastinel has been used in trials studying the treatment of Depressive Disorder, Major and Obsessive-Compulsive Disorder (OCD). |
| DB11850 | Ublituximab | Ublituximab has been used in trials studying the treatment of B-cell Lymphoma, Neuromyelitis Optica, Mantle Cell Lymphoma, Non-Hodgkins Lymphoma, and Marginal Zone Lymphoma, among others. |
| DB11879 | Dusquetide | Dusquetide has been used in trials studying the treatment of Oral Mucositis. |
| DB11884 | Vadastuximab Talirine | Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic Syndrome, Acute Myelogenous Leukemia, and Acute Promyelocytic Leukemia. |
| DB11930 | Varlilumab | Varlilumab has been used in trials studying the treatment of MELANOMA, Skin Ulcer, Burkett's Lymphoma, Mantle cell lymphoma, and Any T-cell Malignancy, among others. |
| DB12077 | Urelumab | Urelumab has been used in trials studying the treatment of Leukemia, Multiple Myeloma, Malignant Tumors, and Cancer - Solid Tumors and B-Cell Non-Hodgkin's Lymphoma. Urelumab is a fully human antibody... |
| DB12136 | Solnatide | Solnatide has been used in trials studying the treatment of Acute Lung Injury. |
| DB12152 | Simtuzumab | Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis. |
| DB12157 | Fasinumab | Fasinumab has been used in trials studying the basic science and treatment of Sciatica, Back Pain, Low Back Pain, Osteoarthritis, Hip, and Abdominal Pain Upper, among others. |
| DB12255 | Vadadustat | Vadadustat has been used in trials studying the treatment of Anemia and Non-dialysis-dependent Chronic Kidney Disease. |
| DB12258 | Abicipar Pegol | Abicipar Pegol has been used in trials studying the treatment of Macular Edema and Macular Degeneration. |
| DB12281 | Luspatercept | An erythroid maturation agent used to treat anemia secondary to beta thalassemia in patients requiring regular red blood cell transfusions. |
| DB12296 | GS-5745 | GS-5745 has been used in trials studying the treatment of Tumors, Breast Cancer, Crohn's Disease, Colorectal Cancer, and Pancreatic Cancer, among others. |
| DB12317 | Vanucizumab | Vanucizumab has been used in trials studying the treatment of ColoRectal Cancer and Advanced/Metastatic Solid Tumors. |
| DB12331 | Labetuzumab govitecan | Labetuzumab govitecan has been used in trials studying the treatment of Colon Cancer, Rectal Cancer, and Metastatic Colorectal Cancer. |
| DB12342 | Ensituximab | Ensituximab has been used in trials studying the treatment of Pancreatic Cancer, Adult, Metastatic Colorectal Cancer, and Metastatic Pancreatic Cancer. |
| DB12344 | Fezakinumab | Fezakinumab has been used in trials studying the treatment of Atopic Dermatitis and Rheumatoid Arthritis. |
| DB12413 | Indusatumab vedotin | Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and Advanced Gastrointestinal Carcinoma, among others. |
| DB12631 | Aclerastide | Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic. |
| DB12683 | Lumretuzumab | Lumretuzumab has been used in trials studying the treatment of Neoplasms, Breast Cancer, Squamous Non-Small Cell Lung Cancer, and Non-Squamous Non-Small Cell Lung Cancer. |
| DB12797 | Ecromeximab | Ecromeximab has been used in trials studying the treatment of Cutaneous Melanoma and Metastatic Melanoma. |
| DB12839 | Pegvaliase | An enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment. |
| DB12840 | Pirnabine | Pirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation. |
| DB12917 | Bimekizumab | Bimekizumab has been used in trials studying the treatment of Psoriatic arthritis, Ankylosing Spondylitis, Chronic Plaque Psoriasis, and Mild to Moderate Psoriasis. |
| DB12950 | Albusomatropin | Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency. |
| DB13000 | PCI-27483 | PCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer. |
| DB13017 | Rovalpituzumab Tesirine | Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others. |
| DB13037 | Namilumab | Namilumab has been used in trials studying the treatment of Plaque Psoriasis and Rheumatoid Arthritis. |
| DB13073 | Tregalizumab | Tregalizumab has been used in trials studying the treatment of Rheumatoid Arthritis. |
| DB13112 | Dolcanatide | Dolcanatide has been investigated in Exposure. |
| DB13138 | Neladenoson bialanate | Neladenoson bialanate has been investigated for the treatment of Heart Failure. |
| DB13140 | Bezlotoxumab | A monoclonal antibody used to reduce the recurrence of Clostridium difficile infections. |
| DB13151 | Anti-inhibitor coagulant complex | A medication used to control bleeding episodes and prevent bleeding episodes in hemophilia A and B. |
| DB13173 | Cerliponase alfa | An enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency. |
| DB13848 | Fluorodopa (18F) | Not Annotated |
| DB13881 | Tisagenlecleucel | A CAR T cell therapy for relapsed or refractory large B-cell lymphoma and diffuse large B-cell lymphoma. |
| DB13884 | Albutrepenonacog alfa | A recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B. |
| DB14012 | Burosumab | A fibroblast growth factor 23 blocking antibody used to treat X-linked hypophosphatemia. |
| DB14040 | Eptinezumab | Use of eptinezumab is intended for migraine prevention [A33105, A33106, A33108]. |
| DB14051 | Malacidin A | Malacidin A is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . |
| DB14052 | Malacidin B | Malacidin B is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . |
| DB14568 | Ivosidenib | An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation. |
| DB14580 | BAN-2401 | BAN-2401 is an experimental drug that is currently in clinical trials for the treament of Alzheimer's disease. |
| DB14707 | Cemiplimab | A programmed death receptor-1 blocking antibody used to treat metastatic cutaneous squamous cell carcinoma. |
| DB14754 | Solriamfetol | Solriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744]. |
| DB14776 | Camrelizumab | Camrelizumab is under investigation in clinical trial NCT03417895 (SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy). |
| DB14777 | Murepavadin | Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment). |
| DB14778 | Setrusumab | Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density). |
| DB14784 | Gancotamab | Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients). |
| DB14843 | Codrituzumab | Codrituzumab is under investigation in clinical trial NCT01507168 (A Study of RO5137382 (GC33) in Patients With Advanced or Metastatic Hepatocellular Carcinoma). |
| DB14864 | Brolucizumab | An anti VEGF-A monoclonal antibody indicated to treat neovascular age related macular degeneration. |
| DB14871 | Xentuzumab | Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)). |
| DB14897 | Parsatuzumab | Parsatuzumab is under investigation in clinical trial NCT01366131 (Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced or Recurrent Non-Squamous... |
| DB14906 | Adafosbuvir | Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335). |
| DB14919 | Rozanolixizumab | Rozanolixizumab is under investigation in clinical trial NCT03861481 (A Study to Assess the Efficacy, Safety and Tolerability of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy). |
| DB14939 | Motixafortide | Motixafortide is under investigation in clinical trial NCT01838395 (Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients). |
| DB14959 | Opicinumab | Opicinumab is under investigation in clinical trial NCT02641041 (Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of BIIB033 in Healthy Japanese Participants). |
| DB14962 | Trastuzumab deruxtecan | An antibody used to treat certain types of unresectable or metastatic HER-2 positive breast cancer. |
| DB14967 | Margetuximab | Margetuximab is under investigation in clinical trial NCT03133988 (Margetuximab Expanded Access Program). |
| DB15014 | Gremubamab | Gremubamab is under investigation in clinical trial NCT02255760 (Phase 1 Randomized Double-blind Placebo Controlled Study to Evaluate Safety and PK of MEDI3902 in Healthy Adults). |
| DB15044 | Tafasitamab | Tafasitamab is under investigation in clinical trial NCT02005289 (Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated... |
| DB15065 | PF-06291874 | PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus). |
| DB15089 | Frovocimab | Frovocimab is under investigation in clinical trial NCT01671085 (A Study of LY3015014 in Healthy Participants With High Cholesterol). |
| DB15090 | Tezepelumab | Tezepelumab is under investigation in clinical trial NCT03406078 (Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma). |
| DB15104 | Telisotuzumab vedotin | Telisotuzumab vedotin is under investigation in clinical trial NCT02099058 (A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Subjects With Advanced Solid Tumors.). |
| DB15128 | Remtolumab | Remtolumab is under investigation in clinical trial NCT02433340 (Phase 2, Multicenter, Open-Label Extension (OLE) Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study). |
| DB15140 | Bempegaldesleukin | Bempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib... |
| DB15158 | BPI-3016 | BPI-3016 is under investigation in clinical trial NCT03188848 (Dose Escalating Study of BPI-3016 in Healthy Subjects). |
| DB15162 | Pegilodecakin | Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer). |
| DB15171 | Tirzepatide | Tirzepatide is under investigation in clinical trial NCT03311724 (A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes). |
| DB15194 | Cotadutide | Cotadutide is under investigation in clinical trial NCT03444584 (Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Subject With Type 2 Diabetes). |
| DB15195 | Mibenratide | Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies). |
| DB15199 | Ciraparantag | Ciraparantag is under investigation in clinical trial NCT01826266 (Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban). |
| DB15252 | Nemolizumab | Nemolizumab is under investigation in clinical trial NCT03921411 (A Pharmacokinetics and Safety Study of Nemolizumab in Adolescent Subjects With Atopic Dermatitis (AD)). |
| DB15277 | Gedivumab | Gedivumab is under investigation in clinical trial NCT01877785 (A Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers). |
| DB15331 | Vocimagene amiretrorepvec | Vocimagene amiretrorepvec is under investigation in clinical trial NCT02576665 (A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca... |
| DB15349 | Sofituzumab vedotin | Sofituzumab vedotin is under investigation in clinical trial NCT01335958 (Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer). |
| DB15354 | Evinacumab | Evinacumab is under investigation in clinical trial NCT03146416 (Study of Evinacumab (REGN1500) in Caucasian and in Japanese Healthy Volunteers). |
| DB15365 | Pegbelfermin | Pegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis). |
| DB15366 | SOR-C13 | SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel). |
| DB15370 | Balixafortide | Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer). |
| DB15466 | Tallimustine | An alkylating agent previously investigated for it's antitumor activity but was stopped due to severe myelotoxicity. |
| DB13925 | Dotatate gallium Ga-68 | Dotatate gallium 68 is one of the most prominent radiopharmaceuticals used in imaging with positron emission tomography. It binds to the somatostatin-2 receptor which is usually overexpressed in many neuroendocrine... |
| DB15531 | Silk sericin | Not Annotated |
| DB15559 | Zenocutuzumab | Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). |
| DB02668 | JE-2147 | Not Available |
| DB01833 | Canavanine | Not Available |
| DB01934 | Arylomycin A2 | Not Available |
| DB03974 | L-homoarginine | Not Available |
| DB03602 | S-benzylglutathione | Not Available |
| DB15575 | Padeliporfin | Not Annotated |
| DB01985 | N-acetyl-L-arginine | Not Available |
| DB02414 | Cyclo(his-pro) | Not Available |
| DB03953 | Thiocitrulline | Not Available |
| DB15582 | Echinomycin | Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis. |
| DB15591 | Atrial natriuretic peptide | Not Annotated |
| DB03686 | S-(4-nitrobenzyl)glutathione | Not Available |
| DB03305 | N(G)-Iminoethylornithine | Not Available |
| DB03376 | 5'-O-(N-(Alanyl)sulfamoyl)adenosine | Not Available |
| DB12199 | TRV-120027 | TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease. |
| DB03901 | 5-Oxoprolinal | Not Available |
| DB15601 | NNZ-2591 | NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life,... |
| DB01714 | Epsilon-N-methyllysine | Not Available |
| DB04701 | S-Methyl glutathione | Not Available |
| DB01739 | L-alloisoleucine | Not Available |
| DB08371 | p-Benzoyl-L-phenylalanine | Not Available |
| DB01751 | Tetraiodothyroacetic acid | Not Available |
| DB08040 | Kelatorphan | Not Available |
| DB02025 | ACV tripeptide | Not Available |
| DB02070 | Kynurenine | Not Available |
| DB02238 | 4-methylthio-2-oxobutanoic acid | Not Available |
| DB02282 | 5'-S-methyl-5'-thioadenosine | Not Available |
| DB02302 | Symmetric dimethylarginine | Not Available |
| DB02571 | Allysine | Not Available |
| DB02987 | Cysteine-S-acetamide | Not Available |
| DB04541 | Cyclo(prolylglycyl) | Not Available |