Cyclopropane

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Cyclopropane
Accession Number
DB13984
Type
Small Molecule
Groups
Experimental
Description

Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive.

Structure
Thumb
Synonyms
  • Ciclopropano
  • Cyclopropan
  • Cyclopropanum
  • Trimethylene
  • Zyklopropan
External IDs
HSDB 812 / RC 270
Categories
UNII
99TB643425
CAS number
75-19-4
Weight
Average: 42.081
Monoisotopic: 42.046950193
Chemical Formula
C3H6
InChI Key
LVZWSLJZHVFIQJ-UHFFFAOYSA-N
InChI
InChI=1S/C3H6/c1-2-3-1/h1-3H2
IUPAC Name
cyclopropane
SMILES
C1CC1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
2,5-Dimethoxy-4-ethylthioamphetamineThe risk or severity of adverse effects can be increased when 2,5-Dimethoxy-4-ethylthioamphetamine is combined with Cyclopropane.
3,4-MethylenedioxyamphetamineThe risk or severity of adverse effects can be increased when 3,4-Methylenedioxyamphetamine is combined with Cyclopropane.
4-Bromo-2,5-dimethoxyamphetamineThe risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Cyclopropane.
4-MethoxyamphetamineThe risk or severity of adverse effects can be increased when 4-Methoxyamphetamine is combined with Cyclopropane.
5-methoxy-N,N-dimethyltryptamineThe risk or severity of adverse effects can be increased when Cyclopropane is combined with 5-methoxy-N,N-dimethyltryptamine.
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Cyclopropane.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolineThe risk or severity of adverse effects can be increased when 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline is combined with Cyclopropane.
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Cyclopropane.
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Cyclopropane.
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Cyclopropane.
Food Interactions
Not Available

References

General References
  1. Bokoch MP, Gelb AW: From the journal archives: cyclopropane: induction and recovery with a bang! Can J Anaesth. 2014 Aug;61(8):763-6. doi: 10.1007/s12630-014-0109-x. Epub 2014 Jan 14. [PubMed:24421247]
External Links
ChemSpider
6111
ChEBI
30365
ChEMBL
CHEMBL1796999
Wikipedia
Cyclopropane

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility10.1 mg/mLALOGPS
logP1.56ALOGPS
logP1.33ChemAxon
logS-0.62ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity13.8 m3·mol-1ChemAxon
Polarizability5.51 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Classification
Not classified

Drug created on January 25, 2018 13:58 / Updated on November 02, 2018 07:48