Cycloparaffins

Name
Cycloparaffins
Accession Number
DBCAT000359
Description

Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawley's Condensed Chemical Dictionary, 11th ed)

Drugs
DrugDrug Description
Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
TramadolA centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression.
Tranexamic acidAn antifibrinolytic agent used for heavy menstrual bleeding.
NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
AcitretinAn oral retinoid used in the treatment of severe psoriasis.
PicrotoxinUsed internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
HexylcaineUsed as a local anesthetic for surface application, infiltration or nerve block
RimantadineAn RNA synthesis inhibitor used to prevent influenza A infection.
AlitretinoinA vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis.
AdenosineA medication used in myocardial perfusion scintigraphy.
NateglinideA meglitinide used to treat non insulin dependent diabetes mellitus.
TretinoinA vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles.
DicyclomineAn antimuscarinic agent used to treat IBS.
AmantadineA medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
EtretinateFor the treatment of severe psoriasis in adults.
IsotretinoinA retinoid used to treat severe recalcitrant acne.
GabapentinAn anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.
SibutramineA norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
PaclitaxelA taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
DocetaxelA taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
1-PhenylcyclohexylamineNot Available
CilastatinA renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
RoflumilastA selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis.
GabaculineNot Available
CyclohexanoneCyclohexanone (also known as oxocyclohexane, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketocyclohexane) is a six-carbon cyclic molecule with a ketone functional group. It is a colorless, oily liquid with an...
AdamantanoneNot Available
FumagillinNot Available
4-OxoretinolNot Available
Isochorismic AcidNot Available
Arotinoid acidArotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
PeridininNot Available
ViolaxanthinNot Available
AdamantaneA tricyclo bridged hydrocarbon. [PubChem]
CyclohexanolMonohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem]
CilomilastInvestigated for use/treatment in chronic obstructive pulmonary disease (COPD).
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
3-Dehydroquinic AcidNot Available
Shikimate-3-PhosphateNot Available
3-DehydroshikimateNot Available
CycloleucineCycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.
MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
VildagliptinA once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.
VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
NeramexaneInvestigated for use/treatment in alzheimer's disease, hearing loss, and pain (acute or chronic).
ApadenosonInvestigated for use/treatment in cardiovascular disorders and inflammatory disorders (unspecified).
FenretinideInvestigated for use/treatment in macular degeneration.
SQ-109Investigated for use/treatment in bacterial infection, infectious and parasitic disease (unspecified), and tuberculosis.
Atl146eInvestigated for use/treatment in inflammatory disorders (unspecified).
Paclitaxel docosahexaenoic acidInvestigated for use/treatment in breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer.
IRX-5183Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified).
ArylacenamideInvestigated for use/treatment in cancer/tumors (unspecified), immunosuppressive, and prostate cancer.
AI-850Investigated for use/treatment in breast cancer and solid tumors.
TranscrocetinateInvestigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes.
Paclitaxel trevatideInvestigated for use/treatment in brain cancer.
TedisamilInvestigated for use/treatment in arrhythmia, atrial fibrillation, and angina.
SaxagliptinAn DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
AR-9281Investigated for use/treatment in hypertension.
AstaxanthinInvestigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma.
PeramivirAn intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days.
DesvenlafaxineAn antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.
AmbroxolAmbroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing.
Beta caroteneA vitamin A precursor found in various nutritional supplements and health products.
CabazitaxelAn antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
MethenamineA urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidNot Available
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanoneNot Available
PlatensimycinNot Available
Prephenic acidNot Available
Ro 12-7310Not Available
LevomilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD).
(4R)-limoneneLimonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to...
CyclopentamineCyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. It has been widely discontinued due to...
BromhexineBromhexine is an expectorant/mucolytic agent. Bromhexine is not available in the United States. It is marketed under the trade name Bisolvon(R) in Germany, England, Belgium, France, Italy, Netherlands, Norway, Sweden,...
TasimelteonA melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder.
ZeaxanthinZeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some...
PentoxyverineA medication used to suppress a cough in the common cold, flu, bronchitis, and sinusitis.
LycopeneAn ingredient found in a variety of supplements and vitamins.
CaramiphenCaramiphen is a cholinergic antagonist used in Parkinson's disease. Additionally, it is used, in combination with phenylpropanolamine, as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal...
TiletamineThis drug is a dissociative anesthetic agent that falls under the drug category of NMDA receptor antagonists. Tiletamine is chemically similar to another dissociative anesthetic, ketamine. Tiletamine hydrochloride, the salt...
CandoxatrilatA dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP,...
OrtataxelOrtataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer.
PeficitinibPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
NavarixinNavarixin has been investigated for the treatment of Asthma.
PevonedistatPevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
TanzisertibTanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.
ArtefenomelArtefenomel has been investigated for the treatment of Malaria.
CrocinCrocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.
LomibuvirLomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
TesetaxelTesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others.
Chlorogenic AcidChlorogenic Acid has been used in trials studying the treatment of Advanced Cancer and Impaired Glucose Tolerance.
AtagabalinAtagabalin has been used in trials studying the treatment of Insomnia, Primary Insomnia, and Nonrestorative Sleep.
Zuretinol acetateZuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).
MK-0557MK0557 has been investigated for the treatment of Schizophrenia and Paranoid Schizophrenia.
DiphencyproneDiphencyprone has been used in trials studying the treatment and basic science of Melanoma, Ultraviolet Rays, Immunosuppression, Neoplasm Metastasis, and Hypersensitivity, Delayed, among others.
PF-03654746PF-03654746 has been investigated for the treatment of Narcolepsy, Schizophrenia, Tourette's Syndrome, and Excessive Daytime Sleepiness.
Squaric acid dibutyl esterSquaric acid dibutyl ester is under investigation in clinical trial NCT01971385 (Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis).
LosmapimodLosmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease.
DasotralineDasotraline is a serotonin, norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of Binge Eating Disorder, Adult Attention Hyperactivity Disorder, Attention Deficit Hyperactivity Disorder, and...
MilataxelMilataxel has been used in trials studying the treatment of Mesothelioma.
PF-03654764PF-03654764 has been used in trials studying the basic science and treatment of Allergic Rhinitis.
GDC-0152GDC-0152 has been used in trials studying the treatment of Solid Cancers.
ABT-384ABT-384 has been used in trials studying the treatment of Alzheimer's Disease.
MK-5108MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.
AZD-9056AZD9056 has been used in trials studying the basic science and treatment of Rheumatoid Arthritis.
BMS-188797BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
BMS-184476BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
BeloranibBeloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
ABC-294640ABC294640 has been used in trials studying the treatment of Diffuse Large B Cell Lymphoma.
LarotaxelLarotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast Neoplasms, and Pancreatic Neoplasms, among others.
AQX-1125AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
LobaplatinLobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, and Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma.
GacyclidineGacyclidine has been used in trials studying the treatment of Tinnitus.
Ambroxol acefyllinateNot Annotated
Fluciclovine (18F)A radiolabelled L-leucine derivative used to image tumors, especially in the prostate.
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
NeltenexineNeltenexine is an elastase inhibitor. It may be useful for preventing pulmonary emphysema.
TromantadineTromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex.
GuaiazulenNot Annotated
MotretinideNot Annotated
BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
IprindoleNot Annotated
RociverineNot Annotated
EberconazoleNot Annotated
TilidineNot Annotated
Paclitaxel poliglumexNot Annotated
CyclopropaneCyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery...
13-cis-12-(3'-Carboxyphenyl)retinoic acidNot Annotated
Quaternium-15Quaternium-15 is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
LuteinXanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance.
Oseltamivir acidNot Available
TNP-470O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms.
ONO-2952ONO-2952 is under investigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome...
MartinostatMartinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer).
TransfluthrinTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
NorbixinNorbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals).
SimotaxelSimotaxel is under investigation in clinical trial NCT00088647 (Study Evaluating MST-997 in Advanced Malignant Solid Tumors).
FucoxanthinFucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion).
BexaroteneA retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
CiclopiroxA broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
EsketamineA NMDA receptor antagonist used for treatment-resistant depression.
ZidebactamZidebactam is under investigation in clinical trial NCT02674347 (MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous Zidebactam in Healthy Adults).
LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
Anhydrovitamin ANot Available
3-(cyclohexylamino)propanesulfonic acidNot Available
Bisphenol ZNot Available
N-EthylretinamideN-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.
Drugs & Drug Targets
DrugTargetType
Vitamin ARetinol dehydrogenase 12target
Vitamin A11-cis retinol dehydrogenasetarget
Vitamin ARetinol dehydrogenase 13target
Vitamin ARetinol-binding protein 5carrier
Vitamin ARetinoid-binding protein 7carrier
Vitamin ARetinol-binding protein 4carrier
Vitamin ARetinol-binding protein 2carrier
Vitamin ARetinal dehydrogenase 2target
Vitamin ARetinal dehydrogenase 1target
Vitamin ALecithin retinol acyltransferasetarget
Vitamin AShort-chain dehydrogenase/reductase 3target
Vitamin AAldehyde dehydrogenase family 1 member A3target
Vitamin AAll-trans-retinol 13,14-reductasetarget
Vitamin ARetinol dehydrogenase 11target
Vitamin ADehydrogenase/reductase SDR family member 4target
Vitamin ARetinol dehydrogenase 14target
Vitamin ARetinol dehydrogenase 8target
Vitamin ACytochrome P450 26A1enzyme
Vitamin AApolipoprotein Dtarget
Vitamin AProstaglandin-H2 D-isomerasetarget
Vitamin ASerum albumincarrier
Vitamin ARetinaldehyde-binding protein 1carrier
Vitamin ARetinol-binding protein 3carrier
Vitamin ARetinol-binding protein 1carrier
Vitamin AReceptor for retinol uptake STRA6transporter
TramadolMu-type opioid receptortarget
TramadolSodium-dependent noradrenaline transportertarget
Tramadol5-hydroxytryptamine receptor 2Ctarget
TramadolKappa-type opioid receptortarget
TramadolSodium-dependent serotonin transportertarget
TramadolCytochrome P450 2D6enzyme
TramadolDelta-type opioid receptortarget
TramadolCytochrome P450 3A4enzyme
TramadolCytochrome P450 2B6enzyme
TramadolAlpha-7 nicotinic cholinergic receptor subunittarget
TramadolMuscarinic acetylcholine receptor M3target
TramadolMuscarinic acetylcholine receptor M1target
TramadolUDP-glucuronosyltransferase 1-1enzyme
TramadolNeurokinin 1 receptortarget
TramadolSodium channel protein type 2 subunit alphatarget
TramadolTransient receptor potential cation channel subfamily V member 1target
TramadolNMDA receptortarget
TramadolAdenosine receptor A1target
TramadolAlpha-2 adrenergic receptorstarget
VenlafaxineSodium-dependent serotonin transportertarget
VenlafaxineSodium-dependent noradrenaline transportertarget
VenlafaxineCytochrome P450 2D6enzyme
VenlafaxineCytochrome P450 3A4enzyme
VenlafaxineSodium-dependent dopamine transportertarget
VenlafaxineP-glycoprotein 1transporter
VenlafaxineATP-binding cassette sub-family G member 2transporter
Tranexamic acidPlasminogentarget
Tranexamic acidSolute carrier family 15 member 2transporter
Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
AcitretinRetinoic acid receptor alphatarget
AcitretinRetinoic acid receptor RXR-betatarget
AcitretinRetinoic acid receptor gammatarget
AcitretinRetinoic acid receptor betatarget
AcitretinRetinoic acid receptor RXR-gammatarget
AcitretinRetinoic acid receptor RXR-alphatarget
AcitretinSerum albumincarrier
AcitretinRetinol-binding protein 1target
AcitretinRetinoic acid receptor RXRtarget
PicrotoxinGamma-aminobutyric acid receptor subunit rho-1target
PicrotoxinGamma-aminobutyric acid receptor subunit alpha-1target
PicrotoxinGlycine receptor subunit alpha-2target
PicrotoxinGlycine receptor subunit alpha-3target
PicrotoxinCytochrome P450 1A1enzyme
PicrotoxinGlutamine synthetaseenzyme
PicrotoxinGlycine receptor subunit alpha-1target
HexylcaineSodium channel protein type 5 subunit alphatarget
HexylcaineSodium channel protein type 10 subunit alphatarget
RimantadineMatrix protein 2target
AlitretinoinRetinoic acid receptor alphatarget
AlitretinoinRetinoic acid receptor RXR-betatarget
AlitretinoinRetinoic acid receptor gammatarget
AlitretinoinRetinoic acid receptor betatarget
AlitretinoinRetinoic acid receptor RXR-gammatarget
AlitretinoinRetinoic acid receptor RXR-alphatarget
AlitretinoinCellular retinoic acid-binding protein 2carrier
AlitretinoinCellular retinoic acid-binding protein 1carrier
AlitretinoinP-glycoprotein 1transporter
AlitretinoinInsulin-like growth factor-binding protein 3target
AlitretinoinPregnancy-specific beta-1-glycoprotein 5target
AlitretinoinCytochrome P450 26C1target
AdenosineAdenosine receptor A3target
AdenosineAdenosine deaminaseenzyme
AdenosineAdenosine kinaseenzyme
AdenosineAdenosine receptor A1target
AdenosineAdenosine receptor A2atarget
AdenosineAdenosine receptor A2btarget
AdenosineSolute carrier family 28 member 3transporter
NateglinideATP-binding cassette sub-family C member 8target
NateglinideCytochrome P450 3A4enzyme
NateglinideCytochrome P450 2C9enzyme
NateglinidePeroxisome proliferator-activated receptor gammatarget
NateglinideCytochrome P450 3A5enzyme
NateglinideCytochrome P450 3A7enzyme
NateglinideSolute carrier family 15 member 1transporter
NateglinideSolute carrier family 15 member 2transporter
NateglinideSolute carrier family 22 member 6transporter
NateglinideMonocarboxylate transporter 1transporter
NateglinideProstaglandin G/H synthase 1enzyme
NateglinideUDP-glucuronosyltransferase 1-9enzyme
NateglinideCytochrome P450 2D6enzyme
NateglinideMultidrug resistance-associated protein 4transporter
NateglinideSerum albumincarrier
NateglinideAlpha-1-acid glycoprotein 1carrier
TretinoinRetinoic acid receptor gammatarget
TretinoinRetinoic acid receptor RXR-betatarget
TretinoinRetinal dehydrogenase 1target
TretinoinRetinoic acid-induced protein 3target
TretinoinRetinoic acid receptor RXR-gammatarget
TretinoinRetinal dehydrogenase 2target
TretinoinRetinoic acid receptor responder protein 1target
TretinoinCytochrome P450 2C8enzyme
TretinoinCellular retinoic acid-binding protein 1transporter
TretinoinCellular retinoic acid-binding protein 2transporter
TretinoinCytochrome P450 2B6enzyme
TretinoinCytochrome P450 3A4enzyme
TretinoinCytochrome P450 3A5enzyme
TretinoinCytochrome P450 2A6enzyme
TretinoinCytochrome P450 3A7enzyme
TretinoinCytochrome P450 2C18enzyme
TretinoinCytochrome P450 2C9enzyme
TretinoinCytochrome P450 4A11enzyme
TretinoinCytochrome P450 1A1enzyme
TretinoinRetinoic acid receptor alphatarget
TretinoinRetinoic acid receptor betatarget
TretinoinLipocalin-1target
TretinoinOdorant-binding protein 2atarget
TretinoinRetinol-binding protein 4target
TretinoinSerum albumincarrier
Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
TretinoinRetinoic acid receptor RXR-alphatarget
TretinoinCytochrome P450 26A1target
TretinoinCytochrome P450 26B1target
TretinoinCytochrome P450 26C1target
TretinoinHematopoietic prostaglandin D synthasetarget
DicyclomineMuscarinic acetylcholine receptor M1target
DicyclomineMuscarinic acetylcholine receptor M2target
AmantadineDopamine D2 receptortarget
AmantadineMatrix protein 2target
AmantadineAromatic-L-amino-acid decarboxylaseenzyme
AmantadineAmine oxidase [flavin-containing] Benzyme
AmantadineSolute carrier family 22 member 2transporter
AmantadineSolute carrier family 22 member 1transporter
AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
AmantadineNeuronal acetylcholine receptor subunit alpha-7target
AmantadineNeuronal acetylcholine receptor subunit alpha-4target
AmantadineNeuronal acetylcholine receptor subunit alpha-3target
EtretinateRetinoic acid receptor alphatarget
EtretinateRetinoic acid receptor RXR-betatarget
EtretinateRetinoic acid receptor gammatarget
EtretinateRetinoic acid receptor betatarget
EtretinateRetinoic acid receptor RXR-gammatarget
EtretinateRetinoic acid receptor RXR-alphatarget
EtretinateCellular retinoic acid-binding protein 1carrier
EtretinateCytochrome P450 19A1enzyme
IsotretinoinRetinoic acid receptor alphatarget
IsotretinoinSerum albumincarrier
IsotretinoinRetinoic acid receptor gammatarget
IsotretinoinCytochrome P450 3A4enzyme
GabapentinAdenosine receptor A1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
GabapentinLarge neutral amino acids transporter small subunit 1transporter
GabapentinVoltage-dependent N-type calcium channeltarget
GabapentinPotassium voltage-gated channel subfamily KQT member 3target
GabapentinPotassium voltage-gated channel subfamily KQT member 5target
SibutramineSodium-dependent serotonin transportertarget
SibutramineSodium-dependent noradrenaline transportertarget
SibutramineCytochrome P450 3A4enzyme
SibutramineSodium-dependent dopamine transportertarget
KetamineGlutamate receptor ionotropic, NMDA 3Atarget
KetamineNeurokinin 1 receptortarget
KetamineCytochrome P450 2B6enzyme
KetamineCytochrome P450 2C9enzyme
KetamineCytochrome P450 3A4enzyme
KetamineDopamine D2 receptortarget
KetamineProstaglandin G/H synthase 1enzyme
KetamineCytochrome P450 2C8enzyme
KetamineDelta-type opioid receptortarget
KetamineSodium-dependent noradrenaline transportertarget
KetamineKappa-type opioid receptortarget
KetamineMu-type opioid receptortarget
KetamineMuscarinic acetylcholine receptortarget
Ketamine5-hydroxytryptamine receptor 2target
Ketamine5-hydroxytryptamine receptor 1target
Ketamine5-hydroxytryptamine receptor 3Atarget
KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
KetamineCholinesterasetarget
KetamineNitric oxide synthase, braintarget
PaclitaxelApoptosis regulator Bcl-2target
PaclitaxelTubulin beta-1 chaintarget
PaclitaxelCytochrome P450 2C8enzyme
PaclitaxelCytochrome P450 3A4enzyme
PaclitaxelCytochrome P450 3A5enzyme
PaclitaxelCytochrome P450 3A7enzyme
PaclitaxelBile salt export pumptransporter
PaclitaxelP-glycoprotein 1transporter
PaclitaxelMultidrug resistance-associated protein 1transporter
PaclitaxelMultidrug resistance-associated protein 7transporter
PaclitaxelCytochrome P450 19A1enzyme
PaclitaxelCytochrome P450 1B1enzyme
PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
PaclitaxelNuclear receptor subfamily 1 group I member 2target
PaclitaxelMicrotubule-associated protein 4target
PaclitaxelMicrotubule-associated protein 2target
PaclitaxelMicrotubule-associated protein tautarget
PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelApoptosis regulator Bcl-2target
DocetaxelTubulin beta-1 chaintarget
DocetaxelCytochrome P450 3A4enzyme
DocetaxelCytochrome P450 3A5enzyme
DocetaxelCytochrome P450 3A7enzyme
DocetaxelP-glycoprotein 1transporter
DocetaxelMultidrug resistance-associated protein 7transporter
DocetaxelCytochrome P450 1B1enzyme
DocetaxelMicrotubule-associated protein 2target
DocetaxelMicrotubule-associated protein 4target
DocetaxelMicrotubule-associated protein tautarget
DocetaxelSolute carrier organic anion transporter family member 1B3transporter
DocetaxelSolute carrier family 22 member 7transporter
DocetaxelATP-binding cassette sub-family G member 2transporter
DocetaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelMultidrug resistance-associated protein 1transporter
DocetaxelNuclear receptor subfamily 1 group I member 2target
CilastatinDipeptidase 1target
CilastatinSolute carrier family 22 member 6transporter
CilastatinSolute carrier family 22 member 8transporter
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
RoflumilastCytochrome P450 3A4enzyme
GabaculineOrnithine aminotransferase, mitochondrialtarget
GabaculineGlutamate-1-semialdehyde 2,1-aminomutasetarget
CyclohexanonePentaerythritol tetranitrate reductasetarget
AdamantanoneCamphor 5-monooxygenasetarget
FumagillinMethionine aminopeptidase 2target
Isochorismic AcidPhenazine biosynthesis protein PhzDtarget
Arotinoid acidRetinoic acid receptor betatarget
AdamantaneCamphor 5-monooxygenasetarget
CyclohexanolAlcohol dehydrogenase 1Btarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
3-Dehydroquinic Acid3-dehydroquinate dehydratasetarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
CycloleucineGlutamate receptor ionotropic, NMDA 1target
MaravirocC-C chemokine receptor type 5target
MaravirocCytochrome P450 3A4enzyme
VildagliptinDipeptidyl peptidase 4target
VogliboseMaltase-glucoamylase, intestinaltarget
NeramexaneGlutamate receptor ionotropic, NMDA 3Atarget
ApadenosonAdenosine receptor A2atarget
FenretinideRetinol-binding protein 4carrier
Atl146eAdenosine receptor A2atarget
Paclitaxel docosahexaenoic acidApoptosis regulator Bcl-2target
ArylacenamideHCG20471, isoform CRA_ctarget
SaxagliptinDipeptidyl peptidase 4target
SaxagliptinCytochrome P450 3A4enzyme
SaxagliptinCytochrome P450 3A5enzyme
SaxagliptinMultidrug resistance-associated protein 1transporter
SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
SaxagliptinSolute carrier family 22 member 8transporter
AR-9281Bifunctional epoxide hydrolase 2target
AstaxanthinNF-kappa-B inhibitor alphatarget
PeramivirNeuraminidasetarget
PeramivirNeuraminidasetarget
PeramivirNeuraminidasetarget
DesvenlafaxineCytochrome P450 3A4enzyme
DesvenlafaxineSodium-dependent serotonin transportertarget
DesvenlafaxineSodium-dependent noradrenaline transportertarget
DesvenlafaxineCytochrome P450 2D6enzyme
DesvenlafaxineSodium-dependent dopamine transportertarget
AmbroxolCytochrome P450 3A4enzyme
Beta caroteneBeta,beta-carotene 15,15'-dioxygenaseenzyme
Beta caroteneFree radicalstarget
Beta caroteneVery low-density lipoprotein receptorcarrier
Beta caroteneRetinol-binding protein 1carrier
Beta caroteneRetinol-binding protein 2carrier
Beta caroteneRetinol-binding protein 3carrier
Beta caroteneRetinol-binding protein 4carrier
Beta caroteneRetinol-binding protein 5carrier
CabazitaxelCytochrome P450 3A4enzyme
CabazitaxelCytochrome P450 3A5enzyme
CabazitaxelCytochrome P450 2C8enzyme
CabazitaxelP-glycoprotein 1transporter
CabazitaxelATP-binding cassette sub-family G member 2transporter
CabazitaxelTubulin alpha-4A chaintarget
CabazitaxelTubulin beta-1 chaintarget
CabazitaxelSolute carrier organic anion transporter family member 1B1transporter
CabazitaxelSolute carrier organic anion transporter family member 1B3transporter
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidRetinoic acid receptor gammatarget
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanoneHeme oxygenase 1target
Platensimycin3-oxoacyl-[acyl-carrier-protein] synthase 2target
Prephenic acidChorismate mutase AroHtarget
Ro 12-7310Cellular retinoic acid-binding protein 2carrier
LevomilnacipranCytochrome P450 3A4enzyme
LevomilnacipranCytochrome P450 2C8enzyme
LevomilnacipranCytochrome P450 2C19enzyme
LevomilnacipranCytochrome P450 2D6enzyme
LevomilnacipranCytochrome P450 2J2enzyme
LevomilnacipranSodium-dependent serotonin transportertarget
LevomilnacipranSodium-dependent noradrenaline transportertarget
LevomilnacipranP-glycoprotein 1transporter
TasimelteonMelatonin receptor type 1Atarget
TasimelteonMelatonin receptor type 1Btarget
TasimelteonCytochrome P450 3A4enzyme
TasimelteonCytochrome P450 1A2enzyme
PentoxyverineSigma non-opioid intracellular receptor 1target
PentoxyverinePotassium voltage-gated channel subfamily H member 2target
PentoxyverineVoltage-gated sodium channel alpha subunittarget
PentoxyverineKappa-type opioid receptortarget
PentoxyverineMu-type opioid receptortarget
CandoxatrilatNeprilysintarget
DasotralineSodium-dependent dopamine transportertarget
DasotralineSodium-dependent serotonin transportertarget
DasotralineSodium-dependent noradrenaline transportertarget
MilataxelTubulin beta-1 chaintarget
MilataxelTubulin beta chaintarget
Ambroxol acefyllinateCytochrome P450 3A Subfamilyenzyme
Fluciclovine (18F)Neutral amino acid transporter B(0)target
Fluciclovine (18F)Y+L amino acid transporter 1target
Fluciclovine (18F)Cationic amino acid transporter 3target
Fluciclovine (18F)Glutamate (NMDA) receptortarget
Fluciclovine (18F)Glutamate receptor 1target
Fluciclovine (18F)Glutamate receptor 2target
Fluciclovine (18F)Glutamate receptor 3target
Fluciclovine (18F)Glutamate receptor 4target
Fluciclovine (18F)Multidrug resistance-associated protein 4transporter
BencyclaneCytochrome P450 3A4enzyme
RociverineMuscarinic acetylcholine receptor M1target
RociverineMuscarinic acetylcholine receptor M2target
RociverineMuscarinic acetylcholine receptor M3target
RociverineMuscarinic acetylcholine receptor M4target
RociverineMuscarinic acetylcholine receptor M5target
LuteinSerum albumincarrier
Oseltamivir acidNeuraminidasetarget
TNP-470Methionine aminopeptidase 2target
BexaroteneRetinoic acid receptor RXR-betatarget
BexaroteneCytochrome P450 3A4enzyme
BexaroteneRetinoic acid receptor RXR-alphatarget
BexaroteneRetinoic acid receptor RXR-gammatarget
BexaroteneCytochrome P450 2C8enzyme
CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1target
EsketamineNMDA receptortarget
EsketamineCytochrome P450 2B6enzyme
EsketamineCytochrome P450 3A4enzyme
EsketamineCytochrome P450 2C19enzyme
EsketamineCytochrome P450 2C9enzyme
EsketamineGlutamate receptor ionotropic, NMDA 2Btarget
EsketamineElongation factor 2target
EsketamineBrain-derived neurotrophic factortarget
EsketamineBDNF/NT-3 growth factors receptortarget
LevomentholTransient receptor potential cation channel subfamily A member 1target
LevomentholTransient receptor potential cation channel subfamily M member 8target
LevomentholTransient receptor potential cation channel subfamily V member 3target
LevomentholKappa-type opioid receptortarget
LevomentholVoltage-dependent L-type calcium channeltarget
LevomentholCytochrome P450 3A4enzyme
Bisphenol ZEstrogen-related receptor gammatarget
N-EthylretinamideRetinol-binding protein 4carrier