Toripalimab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Toripalimab
Accession Number
DB15043
Type
Biotech
Groups
Investigational
Description

Toripalimab is under investigation in clinical trial NCT03919383 (Phase II of Lenvatinib Plus Toripalimab for Advanced HCC).

Synonyms
Not Available
Categories
Not Available
UNII
8JXN261VVA
CAS number
1924598-82-2

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1Active Not RecruitingTreatmentAdvanced Melanoma / Kidney Cancer Stage Iv1
1Active Not RecruitingTreatmentLung Cancer Non-Small Cell Cancer (NSCLC)1
1Active Not RecruitingTreatmentLung Cancers / Malignant Lymphomas1
1Active Not RecruitingTreatmentMalignant Lymphomas1
1Active Not RecruitingTreatmentMelanoma / Urological Cancer1
1CompletedTreatmentBreast Cancer1
1CompletedTreatmentTumors, Solid1
1Not Yet RecruitingTreatmentMelanoma (Skin)1
1RecruitingTreatmentAdvanced Malignancies1
1RecruitingTreatmentLung Cancer Non-Small Cell Cancer (NSCLC) / Second-line Treatment1
1RecruitingTreatmentNasopharyngeal Carcinoma1
1, 2Active Not RecruitingTreatmentEsophageal Squamous Cell Carcinoma (ESCC) / Gastric Adenocarcinoma / Head and Neck Squamous Cell Carcinoma (HNSCC) / Nasopharyngeal Carcinoma1
1, 2Enrolling by InvitationTreatmentALK-Positive Anaplastic Large Cell Lymphoma / EBV-Positive DLBCL, Nos / Follicular Lymphoma Grade IIIb / High-grade B-cell Lymphoma / Lymphoma, Large B-Cell, Diffuse (DLBCL) / Transformed Lymphoma1
1, 2Not Yet RecruitingTreatmentChemoradiotherapy / Gastroesophageal Junction Cancer / PD-11
1, 2Not Yet RecruitingTreatmentChemotherapy Effect / Colonic Neoplasms1
1, 2Not Yet RecruitingTreatmentEpatocellular Carcinoma, Intrahepatic Cholangiocarcinoma1
1, 2Not Yet RecruitingTreatmentPortal Vein Tumor Thrombus / Unresectable Hepatocellular Cancer1
1, 2RecruitingTreatmentColorectal Cancers / Malignant Neoplasm of Colon / Microsatellite Instability-high (MSI-H) / Mismatch Repair-deficient (dMMR) / MSI-H / Neoadjuvant Therapy1
2Active Not RecruitingTreatmentAdvanced Melanoma / Metastatic Melanoma1
2Active Not RecruitingTreatmentEfficacy and Safety1
2Not Yet RecruitingTreatmentAdvanced Biliary Tract Cancer1
2Not Yet RecruitingTreatmentBiliary Tract Neoplasms / Hepatobiliary Neoplasms / Neoplasms, Hepatic1
2Not Yet RecruitingTreatmentEsophageal Squamous Cell Carcinoma (ESCC)1
2Not Yet RecruitingTreatmentLung Cancer Non-Small Cell Cancer (NSCLC)1
2Not Yet RecruitingTreatmentLung Cancer Small Cell Lung Cancer (SCLC)1
2Not Yet RecruitingTreatmentMalignant Neoplasm of Stomach1
2Not Yet RecruitingTreatmentNasopharyngeal Carcinoma1
2Not Yet RecruitingTreatmentNasopharyngeal Carcinoma / Nasopharyngeal Diseases / Nasopharyngeal Neoplasms / Neoplasms, Head and Neck1
2Not Yet RecruitingTreatmentNeoadjuvant Therapy of Non-metastatic Locally Advanced Renal Cell Carcinoma1
2Not Yet RecruitingTreatmentNon-Small-Cell Lung Cancer Stage IV1
2Not Yet RecruitingTreatmentSoft Tissue Sarcoma (STS)1
2Not Yet RecruitingTreatmentSoft Tissue Sarcoma (STS) / Undifferentiated Pleomorphic Sarcoma1
2Not Yet RecruitingTreatmentTransitional Cell Carcinoma1
2RecruitingTreatmentAdvanced Biliary Tract Cancer1
2RecruitingTreatmentAdvanced Biliary Tract Tumors1
2RecruitingTreatmentAdvanced Cholangiocarcinoma1
2RecruitingTreatmentAdvanced Melanoma / Advanced Mucosal Melanoma1
2RecruitingTreatmentAdvanced Non Small Cell Lung Cancer1
2RecruitingTreatmentAdvanced Solid Tumors1
2RecruitingTreatmentBladder Urothelial Carcinoma1
2RecruitingTreatmentCancer, Advanced / Small Cell Carcinoma of Esophagus1
2RecruitingTreatmentCancer, Advanced / Tumors, Solid1
2RecruitingTreatmentEsophageal Squamous Cell Carcinoma by AJCC V8 Stage / Resectable Esophageal Cancer1
2RecruitingTreatmentGastric Adenocarcinoma1
2RecruitingTreatmentHead and Neck Carcinoma1
2RecruitingTreatmentHead and Neck Squamous Cell Carcinoma (HNSCC)1
2RecruitingTreatmentHepatocellular,Carcinoma5
2RecruitingTreatmentLocalized Mucosal Melanoma / Mucosal Melanoma1
2RecruitingTreatmentMalignant Neoplasm of Stomach Stage II / Stage III Gastric Cancer1
2RecruitingTreatmentMelanoma Stage IIIB-IV1
2RecruitingTreatmentMucosal Melanoma1
2RecruitingTreatmentMuscle Invasive Bladder Cancer / Upper Tract Urinary Carcinoma1
2RecruitingTreatmentSarcomas1
2RecruitingTreatmentUnresectable Esophageal Cancer1
2WithdrawnTreatmentHepatocellular,Carcinoma1
2, 3RecruitingTreatmentHepatocellular,Carcinoma1
2, 3RecruitingTreatmentNeuroendocrine Carcinoma of the Bladder1
3Not Yet RecruitingTreatmentStage IIIA Non-Small Cell Lung Cancer1
3RecruitingTreatmentAdvanced or Metastatic Esophageal Squamous Cell Cancer Without Previous Systemic Chemotherapy1
3RecruitingTreatmentHead/Neck Neoplasm1
3RecruitingTreatmentLiver Cancer1
3RecruitingTreatmentLung Cancer Non-Small Cell Cancer (NSCLC)1
3RecruitingTreatmentRecurrent or Metastatic NPC1
3RecruitingTreatmentTreatment-naive Advanced Non-small Cell Lung Cancer1
4Not Yet RecruitingTreatmentEsophageal Squamous Cell Carcinoma (ESCC)1
Not AvailableNot Yet RecruitingNot AvailableBreast Cancer / Lung Cance / Melanoma1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on May 20, 2019 08:44 / Updated on February 02, 2020 03:19