Esophageal Candidiasis

Also known as: Esophageal candidiasis / Candidiasis, Esophageal / Candidiasis of the esophagus / Esophageal thrush / Candidiasis of the oesophagus / Candida oesophagitis / Candida esophagitis / Oesophageal candidiasis / Esophageal candida / Oesophageal candida / Candidal esophagitis / Candidal oesophagitis / Candida of oesophagus / Candida of esophagus / Oesophageal thrush

DrugDrug NameDrug Description
DB00362AnidulafunginAn antifungal used in the treatment of several types of candida infections.
DB00520CaspofunginAn echinocandin used to treat a variety of fungal infections.
DB00196FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
DB01167ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
DB01141MicafunginAn antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.
DB01263PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
DB00582VoriconazoleA triazole compound used to treat fungal infections.
DrugDrug NameTargetType
DB00362Anidulafungin1,3-beta-glucan synthase component FKS1target
DB00520CaspofunginSolute carrier family 22 member 1transporter
DB00520CaspofunginP-glycoprotein 1transporter
DB00520CaspofunginSolute carrier family 22 member 6transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B1transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B3transporter
DB00520CaspofunginCytochrome P450 3A4enzyme
DB00520Caspofungin1,3-beta-glucan synthase component FKS1target
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleP-glycoprotein 1transporter
DB00196FluconazoleCytochrome P450 51target
DB00196FluconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleP-glycoprotein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01141MicafunginArylsulfatase Aenzyme
DB01141MicafunginCatechol O-methyltransferaseenzyme
DB01141Micafungin1,3-beta-glucan synthase component FKS1target
DB01263PosaconazoleCytochrome P450 3A4enzyme
DB01263PosaconazoleP-glycoprotein 1transporter
DB01263PosaconazoleCytochrome P450 51target
DB00582VoriconazoleCytochrome P450 2C19enzyme
DB00582VoriconazoleCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C9enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00582VoriconazoleCytochrome P450 3A5enzyme
DB00582VoriconazoleCytochrome P450 3A7enzyme
DB00582VoriconazoleProstaglandin G/H synthase 1enzyme
DB00582VoriconazoleCytochrome P450 51target
DB00582VoriconazoleCytochrome P450 2B6enzyme
DrugDrug NamePhaseStatusCount
DB01141Micafungin1Completed2
DB00520Caspofungin2Completed1
DB00196Fluconazole3Completed1
DB00681Amphotericin BNot AvailableCompleted1
DB00520CaspofunginNot AvailableCompleted1
DB00196FluconazoleNot AvailableCompleted3
DB01167ItraconazoleNot AvailableCompleted1
DB01026KetoconazoleNot AvailableCompleted1