Clinically Isolated Syndrome (CIS)

Also known as: Clinically Isolated Syndrome / Clinically Isolated Syndromes

DrugDrug NameDrug Description
DB14783Diroximel fumarateA drug used for the treatment of relapsing forms of Multiple Sclerosis (MS).
DB08868FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19.
DB12612OzanimodA sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD).
DB12371SiponimodA medication used to treat relapsing multiple sclerosis.
DrugDrug NameTargetType
DB14783Diroximel fumarateLiver esterasesenzyme
DB14783Diroximel fumarateNeuronal acetylcholine receptor subunit alpha-10target
DB08868FingolimodSphingosine 1-phosphate receptor 5target
DB08868FingolimodSphingosine kinase 1enzyme
DB08868FingolimodCytochrome P450 2E1enzyme
DB08868FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
DB08868FingolimodHistone deacetylase 1target
DB08868FingolimodExcitatory amino acid transporter 2transporter
DB08868FingolimodExcitatory amino acid transporter 1transporter
DB08868FingolimodP-glycoprotein 1transporter
DB08868FingolimodMultidrug resistance-associated protein 1transporter
DB08868FingolimodSphingosine 1-phosphate receptor 1target
DB08868FingolimodSphingosine 1-phosphate receptor 4target
DB08868FingolimodSphingosine 1-phosphate receptor 3target
DB12612OzanimodSphingosine 1-phosphate receptor 1target
DB12612OzanimodSphingosine 1-phosphate receptor 5target
DB12612OzanimodAmine oxidase [flavin-containing] Btransporter
DB12612OzanimodATP-binding cassette sub-family G member 2transporter
DB12612OzanimodP-glycoprotein 1transporter
DB12612OzanimodFatty aldehyde dehydrogenaseenzyme
DB12612OzanimodAlcohol dehydrogenase class-3enzyme
DB12612OzanimodArylamine N-acetyltransferase 2enzyme
DB12612OzanimodCytochrome P450 2C8enzyme
DB12612OzanimodAmine oxidase [flavin-containing] Benzyme
DB12612OzanimodAldo-keto reductase family 1 member C1enzyme
DB12612OzanimodAldo-keto reductase family 1 member C2enzyme
DB12612OzanimodCytochrome P450 3A4enzyme
DB12371SiponimodSphingosine 1-phosphate receptor 5target
DB12371SiponimodSphingosine 1-phosphate receptor 1target
DB12371SiponimodCytochrome P450 3A4enzyme
DB12371SiponimodCytochrome P450 2C9enzyme
DrugDrug NamePhaseStatusCount
DB00959Methylprednisolone2Terminated1
DB14631Prednisolone phosphate2Terminated1
DB00060Interferon beta-1a3Completed2
DB01017Minocycline3Completed1
DB01017Minocycline3Recruiting1
DB00060Interferon beta-1a4Completed1
DB11988OcrelizumabNot AvailableNot Yet Recruiting1