Antimony potassium tartrate
Star0
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Antimony potassium tartrate
- DrugBank Accession Number
- DB15587
- Background
Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 667.87
Monoisotopic: 665.737 - Chemical Formula
- C8H10K2O15Sb2
- Synonyms
- Antimony potassium tartrate
- Potassium antimonyl D-tartrate
- Potassium antimonyl tartrate
- Tartar emetic
- Tartarized antimony
- Tartox
- Tartrated antimony
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination for symptomatic treatment of Coughing Combination Product in combination with: Morphine (DB00295), Glycyrrhiza glabra (DB14312), Licorice (DB10675) •••••••••••• ••••••••• •••••••••• Used in combination for symptomatic treatment of Dry throat Combination Product in combination with: Glycyrrhiza glabra (DB14312), Licorice (DB10675), Morphine (DB00295) •••••••••••• ••••••••• •••••••••• Used in combination for symptomatic treatment of Phlegm Combination Product in combination with: Glycyrrhiza glabra (DB14312), Morphine (DB00295), Licorice (DB10675) •••••••••••• ••••••••• •••••••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Carboxylic acids and derivatives
- Sub Class
- Dicarboxylic acids and derivatives
- Direct Parent
- Dicarboxylic acids and derivatives
- Alternative Parents
- Monosaccharides / Fatty acids and conjugates / Organic antimony salts / Carboxylic acid salts / Carboxylic acids / Organic potassium salts / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds / Alkoxides show 1 more
- Substituents
- Aliphatic acyclic compound / Alkoxide / Carbonyl group / Carboxylic acid / Carboxylic acid salt / Dicarboxylic acid or derivatives / Fatty acid / Hydrocarbon derivative / Monosaccharide / Organic alkali metal salt show 8 more
- Molecular Framework
- Not Available
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- DL6OZ476V3
- CAS number
- 28300-74-5
- InChI Key
- WBTCZEPSIIFINA-MSFWTACDSA-J
- InChI
- InChI=1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4/t2*1-,2-;;;;;;;/m11......./s1
- IUPAC Name
- diantimony(3+) dipotassium bis((2R,3R)-2,3-dioxidobutanedioate) trihydrate
- SMILES
- O.O.O.[K+].[K+].[Sb+3].[Sb+3].[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O.[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O
References
- General References
- Not Available
- External Links
- KEGG Drug
- D02959
- ChemSpider
- 32699395
- 981
- Wikipedia
- Antimony_potassium_tartrate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 22.4 mg/mL ALOGPS logP 1.01 ALOGPS logP -1.8 Chemaxon logS -1.4 ALOGPS pKa (Strongest Acidic) 2.72 Chemaxon pKa (Strongest Basic) -4.3 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 126.38 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 68.99 m3·mol-1 Chemaxon Polarizability 10.22 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 10, 2019 19:00 / Updated at February 21, 2021 18:55