Displaying drugs 3751 - 3775 of 11559 in total
Methylnaltrexone
Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Description: … It is also a weak CYP2D6 inhibitor. FDA approved in 2008. ... Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract …
Nesiritide
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. ... Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea …
Lacidipine
Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia . It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce...
Approved
Investigational
Matched Description: … Lacidipine is a highly lipophilic molecule that interacts with the biological membranes. ... Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity ... Compared to other dihydropyridine calcium antagonists, lacidipine exhibits a greater antioxidant activity …
Tafluprost
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. ... A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma …
Hesperidin
Hesperidin is a flavan-on glycoside found in citrus fruits.
Approved
Investigational
Matched Description: … Hesperidin is a flavan-on glycoside found in citrus fruits. …
Diethylstilbestrol
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Description: … It was also used formerly as a growth promoter in animals. ... A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. ... to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a …
Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen
Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Description: … Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine ... factor H binding protein (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A ... It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated …
Rifampicin
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts...
Approved
Matched Description: … A semisynthetic antibiotic produced from Streptomyces mediterranei. ... It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. ... In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex …
Hyaluronidase (human recombinant)
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Description: … A purified preparation of the enzyme recombinant human hyaluronidase. ... DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). ... Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a …
Influenza B virus B/Brisbane/60/2008 hemagglutinin antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Glycol salicylate
Glycol salicylate, also known as 2-hydroxyethyl salicylate, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic in patches used to provide relief for mild to...
Approved
Matched Description: … Glycol salicylate, also known as _2-hydroxyethyl salicylate_, is a benzoate ester formed from the condensation ... Glycol salicylate (GS), composed of salicylic acid (SA) and ethylene glycol, is a non-steroidal anti-inflammatory …
Influenza B virus B/Brisbane/60/2008 hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Influenza B virus B/Brisbane/60/2008 hemagglutinin antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Unoprostone
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate.
The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. ... Ophthalmic Solution 0.15% is a synthetic docosanoid. …
DL-dimyristoylphosphatidylglycerol
DL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Approved
Matched Description: … DL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations …
Metergoline
Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and agonist at dopamine receptors. Its use has been studied in various clinical settings such as a treatment for seasonal...
Approved
Matched Description: … Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and ... Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors ... [A27181] Its use has been studied in various clinical settings such as a treatment for seasonal affective …
Ragweed pollen extract
Ragweed pollen extract has been developed by Curalogic. The company has initiated a phase III trial with its product for oral immunotherapy of ragweed allergy. While traditional disease-modifying immunotherapeutics are administered by subcutaneous injection, Curalogic has developed a more convenient orally administered drug.
Approved
Investigational
Matched Description: … The company has initiated a phase III trial with its product for oral immunotherapy of ragweed allergy ... disease-modifying immunotherapeutics are administered by subcutaneous injection, Curalogic has developed a …
Vanillyl butyl ether
Vanillyl butyl ether is an ether of monohydroxybenzoic acid. It is added to food products as a flavoring agent. It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.
Approved
Matched Description: … It is added to food products as a flavoring agent. ... It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent …
Benziodarone
Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz. It is used in the treatment of gout . It was withdrawn from France markets and British markets due to its effects causing Jaundice in patients [T487, A175636].
Approved
Withdrawn
Matched Description: … Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz …
Dosulepin
Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. Dosulepin inhibits...
Approved
Matched Description: … Dosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits ... Its hydrochloride form is a common active ingredient in different drug formulations. ... Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic …
Valrubicin
Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Description: … It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. ... Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the …
Polydatin
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis …
Phenoxybenzamine
An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Approved
Matched Description: … It has been used to treat hypertension and as a peripheral vasodilator. …
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Description: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a …
Displaying drugs 3751 - 3775 of 11559 in total