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Displaying drugs 4426 - 4450 of 11307 in total

CEP-1347

CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Investigational
Matched Description: … CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults …

DiaPep 277

DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Investigational
Matched Description: … DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460). …
Matched Categories: … Heat-Shock Proteins …

Aloe vera leaf

Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Matched Description: … It is a perennial succulent xerophyte with elongated leaves that contain a clear gel. ... Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern ... While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and …
Matched Mixtures name: … Alcortin A ... Alcortin A …

NeuroCell-PD

Investigational

Onalespib

Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …

Tea tree oil

Tea tree oil is an essential oil derived mainly from the Australian native plant Melaleuca alternifolia via steam distillation of the of the leaves and terminal branches . It may be referred to as Melaleuca alternifolia oil. It has been a popular ingredient in a variety of household and cosmetic...
Experimental
Nutraceutical
Matched Description: … It has been a popular ingredient in a variety of household and cosmetic products due to its antiseptic …
Matched Mixtures name: … Muscle and Joint Heat Cream …

Clomethiazole

Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Description: … It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic ... Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. ... It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Dibromothymoquinone

At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]
Experimental
Matched Description: … this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a …

mRNA-3705

mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.
Investigational
Matched Description: … mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. …

Recombinant human CD4 immunoglobulin G

Investigational

Taniraleucel

Investigational

Theralizumab

Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational
Matched Description: … Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and …

Pentetrazol

Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) receptor antagonist that was approved by the FDA until 1982.
Experimental
Withdrawn
Matched Iupac: … 5H,6H,7H,8H,9H-[1,2,3,4]tetrazolo[1,5-a]azepine …
Matched Description: … Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) …

Gestodene

Gestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol and 75 mcg of gestodene.
Investigational
Matched Iupac: … 9aR,9bS,11aS)-11a-ethyl-1-ethynyl-1-hydroxy-1H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Gestodene is a progestogen hormonal contraceptive. …
Matched Mixtures name: … GYNOVIN ® CD ... GYNOVIN CD GRAGEAS ... MILVANE CD GRAGEAS …

PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE

Experimental
Matched Iupac: … 4-{[6-(2,6-dichlorobenzoyl)imidazo[1,2-a]pyridin-2-yl]amino}benzene-1-sulfonamide …

Fadrozole

Investigational
Matched Iupac: … 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile …

Trastuzumab duocarmazine

Trastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Investigational

TTX-MC138

TTX-MC138 is an antisense oligonucleotide targeting miR-10b. It is under investigation for the treatment of various metastatic cancers.
Investigational

Carotuximab

Investigational

Bersanlimab

Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational

Xylose-Derived Imidazole

Experimental
Matched Iupac: … (6R,7S,8S)-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …

Nafamostat

Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing...
Investigational
Matched Description: … Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid …

Mevastatin

Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 ... times greater than the HMG-CoA substrate itself. ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …

Citronella oil

Experimental
Matched Mixtures name: … AXE BRAND HEAT OIL …

mRNA-3927

mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Matched Description: … carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). ... consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA …
Displaying drugs 4426 - 4450 of 11307 in total