Displaying drugs 526 - 550 of 11564 in total
Riltozinameran
The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). As of November 2022, it is the primary circulating variant of...
Approved
Investigational
Matched Description: … The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. …
Mosunetuzumab
Mosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody. It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells. The standard of care for patients with B-cell lymphoma includes an anti-CD20 monoclonal antibody, such as...
Approved
Investigational
Matched Description: … Mosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody. ... circumvent resistance to [rituximab] in patients with follicular lymphoma,[A249320,L42230] and unlike CAR-T ... as follicular lymphoma (FL), chronic lymphocytic leukemia (CLL) or aggressive B-cell lymphoma, have a …
Sulfacetamide
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Mixtures name: … Sodium Sulfacetamide and Sulfur Clarifying Wash in a Urea Vehicle …
Procaine
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. …
Doconexent
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. ... The amino-phospholipid DHA is found at a high concentration across several brain subcellular fractions …
Iopromide
Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Although iopromide can cause several serious adverse effects, including...
Approved
Matched Description: … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. ... It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, ... favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Lamotrigine
Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Description: … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. …
Infliximab
Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in...
Approved
Matched Description: … Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody ... Inflectra, a first biosimilar drug product, was approved in 2016. ... Infliximab is produced by a recombinant cell line cultured by continuous perfusion. …
Respiratory syncytial virus vaccine, adjuvanted
Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
Procaterol
A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Matched Description: … A long-acting beta-2-adrenergic receptor agonist. ... It is a potent bronchodilator that may be administered orally or by aerosol inhalation. …
Clenbuterol
A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Approved
Investigational
Vet approved
Matched Description: … It is used as a bronchodilator in asthma. ... A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. …
Medical air
Medical air is supplied by a special air compressor to patient care areas using clean outside air.
Approved
Vet approved
Matched Description: … Medical air is supplied by a special air compressor to patient care areas using clean outside air. …
Eladocagene exuparvovec
Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that causes severe disability in pediatric patients.[L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene...
Approved
Investigational
Matched Description: … Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses ... human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and …
Encorafenib
Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell division, differentiation, and secretion. Mutations in this gene,...
Approved
Investigational
Matched Description: … Encorafenib, also known as _BRAFTOVI_, is a kinase inhibitor. ... Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in ... [L12216] This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts …
Copper Cu-64
Copper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including the +1 state tend to be more unstable. It is used in molecular radiotherapy and positron emission tomography.
Approved
Matched Description: … Copper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including …
Netilmicin
Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site. The bactericidal effect...
Approved
Investigational
Matched Description: … Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Ammonia
Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Although ammonia is used as a food additive in the anhydrous form and serves as a...
Approved
Matched Description: … It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. ... Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal ... Although ammonia is used as a food additive in the anhydrous form and serves as a starting material in …
Alcloxa
Approved
Arbutin
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Description: … plant in the genus _Arctostaphylos_ and other plants commonly in the _Ericaceae_ family, arbutin is a ... It has also been used as an anti-infective for the urinary system as well as a diuretic [F43]. ... Most commonly, it is an active ingredient in skincare and cosmetic products as a skin-lightening agent …
Rebamipide
Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cefiderocol
Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam antibiotics.[FDA Label] Unlike other agents in this category, cefiderocol is a siderophore able to undergo active transport into the bacterial cell through iron channels. It represents a significant addition to antibacterial treatment option as...
Approved
Investigational
Matched Description: … Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam ... [A189150] A concern noted in the trial was a 0.3% higher rate of all cause mortality, the cause of which ... [FDA Label] Unlike other agents in this category, cefiderocol is a siderophore able to undergo active …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Levoleucovorin
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Description: … This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible ... Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... As methotrexate functions as a DHFR inhibitor to prevent DNA synthesis in rapidly dividing cells, it …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Trimethaphan
A nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia, and to induce hypotension during surgery.
Approved
Investigational
Matched Description: … A nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia …
Fospropofol
Fospropofol is a water soluble prodrug and is converted to propofol in the liver. Fospropofol is a short acting hypnotic/sedative/anesthetic agent. Unlike propofol, does not cause injection-site pain as it is unable to activate TRPA1. FDA approved in December 2008.
Fospropofol is a Schedule IV controlled substance in the United...
Approved
Illicit
Investigational
Matched Description: … Fospropofol is a short acting hypnotic/sedative/anesthetic agent. ... Fospropofol is a water soluble prodrug and is converted to propofol in the liver. ... Fospropofol is a Schedule IV controlled substance in the United States under the Controlled Substances …
Displaying drugs 526 - 550 of 11564 in total