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Displaying drugs 826 - 850 of 13635 in total

Chlorquinaldol

Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment...
Approved
Matched Description: … for the treatment of bacterial vaginosis. ... [F4549] It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa ... Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. …

Cefmetazole

A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Approved
Investigational
Matched Description: … It has a high rate of efficacy in many types of infection and to date no severe side effects have been ... A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Naldemedine

Naldemedine is an opioid receptor antagonist [FDA Label]. It is a modified form of DB00704 to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. Naldemedine was approved in 2017 in both the US and...
Approved
Investigational
Matched Description: … Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation ... It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight ... and polar surface area resulting in restricted transport across the blood brain barrier. …
Matched Categories: … Drugs for Constipation …

Ceforanide

Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to...
Approved
Matched Description: … It has a longer elimination half-life than any currently available cephalosporin. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Meprobamate

A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated)....
Approved
Illicit
Matched Description: … reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. ... It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia ... A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses …

Meticillin

One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Description: … One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Linagliptin

Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Description: … Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes ... Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, …
Matched Categories: … Drugs Used in Diabetes …

Phenyltoloxamine

Phenyltoloxamine is an antihistamine drug with sedative and analgesic effects. It is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. It is available in combination products that also contain other analgesics and antitussives such as acetaminophen. Phenyltoloxamine citrate is the more common salt form...
Approved
Matched Description: … Nevertheless, phenyltoloxamine is used to a fairly limited extent in contemporary medicine, with only ... It is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. ... by its chemical nature as a first-generation H1 antihistamine that is capable of crossing the blood-brain …

Dermatophagoides pteronyssinus

Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Description: … as a treatment for dust mite allergies. ... This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue ... Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous …

Chlorpropamide

Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Description: … Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes ... Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk ... Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination …
Matched Categories: … Drugs Used in Diabetes …

Mirvetuximab soravtansine

Mirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide linker to the genotoxic compound DM4 (also known as soravtansine or ravtansine).[A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1....
Approved
Investigational
Matched Description: … [L43967,L43972] It was subsequently granted full approval in March 2024.[L50306] ... A254382] On November 2022, the FDA granted accelerated approval to mirvetuximab soravtansine-gynx for ... [A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1. …

Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Mixtures name: … Efluelda Injektionssuspension in einer Fertigspritze …

Factor XIII (human)

Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key...
Approved
Investigational
Matched Description: … For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous ... in increased mechanical strength and resistance to fibrinolysis of the fibrin clot. ... enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade …

Terbutaline

Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.
Approved
Matched Description: … [A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients. ... Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s …
Matched Categories: … Adrenergics for Systemic Use ... Drugs for Obstructive Airway Diseases …

Nylidrin

Nylidrin, also known as buphenine belongs to the category of drugs called vasodilators, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric patients with mild to moderate symptoms of cognitive, emotional...
Approved
Matched Description: … Nylidrin is a peripheral vasodilator. ... Nylidrin is utilized to treat several disorders that may benefit from increased blood flow (for example ... Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric …

Asparagine

A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Description: … A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain …

Nilutamide

Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of...
Approved
Investigational
Matched Description: … Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen ... Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. …

Grepafloxacin

Grepafloxacin is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Due to the QTc-prolonging potential, as indicated by the changes in the QT interval on the electrocardiogram, and the risk for cardiovascular adverse events, grepafloxacin was withdrawn in the United States.
Approved
Investigational
Withdrawn
Matched Description: … , and the risk for cardiovascular adverse events, grepafloxacin was withdrawn in the United States. ... Due to the QTc-prolonging potential, as indicated by the changes in the QT interval on the electrocardiogram …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Cefditoren

Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Chikungunya vaccine (live, attenuated)

Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952. It is spread primarily by the bite of infected mosquitos of the Aedes genus. Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia. Prior to...
Approved
Matched Description: … Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in ... [L48726] It is approved for use in patients 18 years of age and older who are at high-risk of exposure ... [L48786] There are no approved treatments for active chikungunya virus infection. …

Cinoxacin

Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

p-Phenylenediamine

Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …

Aspergillus fumigatus

Aspergillus fumigatus is a fungus which can provoke allergic reactions. Aspergillus fumigatus extract is used in allergenic testing.
Approved
Matched Description: … Aspergillus fumigatus extract is used in allergenic testing. ... Aspergillus fumigatus is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … A Mold Mixture ... A Mold Mixture ... A Mold Mixture …

Ferric maltol

Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate. Ferric maltol has been described in literature since at least the late 1980s as a potential treatment for iron deficiency....
Approved
Matched Description: … [A189288] Ferric maltol has been described in literature since at least the late 1980s as a potential ... treatment for iron deficiency. ... with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in …

Rupatadine

Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...
Approved
Matched Description: … It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for ... used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria ... Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is …
Matched Categories: … Antihistamines for Systemic Use …
Displaying drugs 826 - 850 of 13635 in total