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Displaying drugs 926 - 950 of 13643 in total

Podophyllin

Podophyllin is a resin extracted from the roots of Podophyllum peltatum (American mandrake) and Podophyllum emodi, which contains numerous compounds, amongst which is podophyllin (as well as the drug podophyllotoxin). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Approved
Matched Description: … Podophyllin arrests mitosis in metaphase. ... Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Fluocortolone

Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
Approved
Withdrawn
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Corticosteroids for Systemic Use, Plain …

Norgestrel

Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantiomer (levonorgestrel) is biologically active.
Approved
Matched Description: … Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral ... Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel …
Matched Categories: … Hormonal Contraceptives for Systemic Use …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Description: … [A192987] Chloramphenicol is a bacteriostatic antibiotic. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …

Sultamicillin

Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TYCLAR® 250MG/5ML POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL. …

Human papillomavirus type 16 L1 capsid protein antigen

Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... major capsid (L1) protein of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in …
Matched Mixtures name: … GARDASIL SUSPENSION FOR INJECTION ... GARDASIL 9 SUSPENSION FOR INJECTION …

Lonapegsomatropin

Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone (somatropin) indicated for the treatment of children 1 year and older, weighing at least 11.5 kg, with growth failure due to insufficient growth hormone secretion.[A237605,L36380,L36405] Unlike somatropin, which requires daily dosing, lonapegsomatropin can...
Approved
Investigational
Matched Description: … hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least 11.5 ... Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth ... L36380,L36405] Unlike somatropin, which requires daily dosing, lonapegsomatropin can be administered as a …

Iodide I-131

Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Description: … Low levels of beta radiation are also known for causing cancer as this dose is highly mutagenic. ... Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of ... Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its …

Dyclonine

Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Description: … It may also be found in some Cepacol sore throat spray products. ... Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. …
Matched Products: … Sucrets for Kids …

Trimetrexate

A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Approved
Investigational
Matched Description: … pneumonia in AIDS patients. ... A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. ... It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis …

Acheta domesticus

House cricket allergenic extract is used in allergenic testing.
Approved
Matched Description: … House cricket allergenic extract is used in allergenic testing. …

Xenon-133

Xenon-133 is an inhaled radionuclide used for lung imaging, imaging blood flow in the brain, and to assess pulmonary function.
Approved
Matched Description: … Xenon-133 is an inhaled radionuclide used for lung imaging, imaging blood flow in the brain, and to assess …

Sinapultide

Sinapultide (also known as KL4 peptide) is a synthetic protein used to mimic human lung surfactant protein B. This protein has a weight of 2469.40. Sinapultide is a 21-residue peptide made up of lysine (K) and leucine (L) residues with the sequence KLLLLKLLLLKLLLLKLLLLK (KL4), in aqueous dispersion with the phospholipids...
Approved
Matched Description: … [L2502] Windtree Therapeutics plans a phase III trial for Respiratory distress syndrome in 2018. ... [L2505] Respiratory distress syndrome (RDS) is a major cause of mortality and morbidity in preterm ... , and thereafter, to potentially address a range of indications in neonatal, pediatric and adult critical …

Netupitant

Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy. Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai...
Approved
Investigational
Matched Description: … Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron ... Netupitant is a neurokinin 1 receptor antagonist. ... for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including …

Ravulizumab

Ravulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. Ravulizumab was engineered from eculizumab, another complement inhibitor, to increase the duration of action and reduce the frequency of drug administration. It works by blocking...
Approved
Investigational
Matched Description: … It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. ... Ravulizumab is a potent and selective complement 5 (C5) inhibitor. ... nocturnal hemoglobinuria and atypical hemolytic uremic syndrome in children and adults. …

Riltozinameran

The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). As of November 2022, it is the primary circulating variant of...
Approved
Investigational
Matched Description: … The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. ... It is administered in combination with [tozinameran] for active immunization against COVID-19 caused …

Piroxicam

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in ... treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …

Desirudin

Desirudin is a direct inhibitor of human thrombin. It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide...
Approved
Matched Description: … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients ... present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. ... Desirudin has a chemical formula of C287H440N80O110S6 with a molecular weight of 6963.52. …

Hydrocortisone butyrate

Approved
Vet approved
Matched Iupac: … hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …

Porfimer sodium

The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in...
Approved
Investigational
Matched Description: … The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins ... It is the first drug to be approved in the use of photodynamic therapy in the United States. ... It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with …
Matched Categories: … Photosensitizing Agents for Phototherapy ... Sensitizers Used in Photodynamic/radiation Therapy …

Zinc ascorbate

Approved
Nutraceutical
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Human papillomavirus type 33 L1 capsid protein antigen

Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33. The vaccine is prepared from the purified...
Approved
Matched Description: … Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... (VLPs) of the major capsid (L1) protein of HPV Type 33 which are produced by separate fermentations in …
Matched Mixtures name: … GARDASIL 9 SUSPENSION FOR INJECTION …

Cotton seed

Cotton seed allergenic extract is used in allergenic testing.
Approved
Matched Description: … Cotton seed allergenic extract is used in allergenic testing. …
Matched Products: … Cotton Seed for Diagnostic Use Only …

Racephedrine

Approved
Experimental

Lapyrium

Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products . It is commonly found formulated as lapyrium chloride.
Approved
Matched Description: … Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various …
Displaying drugs 926 - 950 of 13643 in total