Displaying drugs 151 - 175 of 12357 in total
Mavacamten
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Matched Synonyms: … 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart …
Clidinium
Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also...
Approved
Matched Synonyms: … 3-(2-Hydroxy-2,2-diphenyl-acetoxy)-1-methyl-1-azonia-bicyclo[2.2.2]octane ... 3-hydroxy-1-methylquinuclidinium benzilate ester …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Hydrocortisone butyrate
Approved
Vet approved
Matched Iupac: … ,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H …
Sumatriptan
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Synonyms: … (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide ... 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide ... 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … IMIGRAN NASAL SPRAY 20 MG ... IMIGRAN 20 MG/DOZ NAZAL SPREY ... SUTRIP 100 MG TABLET, 2 ADET …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … IMIGRAN NASAL SPRAY 20 MG ... IMIGRAN 20 MG/DOZ NAZAL SPREY ... SUTRIP 100 MG TABLET, 2 ADET …
Calcium glycerophosphate
Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Iupac: … calcium 2-(phosphonooxy)propane-1,3-diol …
Matched Description: … Calcium glycerophosphate is a [DB01373] salt of glycerophosphoric acid that forms a white, fine, slightly ... The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient …
Matched Mixtures name: … Somarexin and C 1000 ... Alsimine W Vitamins A D …
Matched Description: … Calcium glycerophosphate is a [DB01373] salt of glycerophosphoric acid that forms a white, fine, slightly ... The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient …
Matched Mixtures name: … Somarexin and C 1000 ... Alsimine W Vitamins A D …
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... L-β-3-indolylalanine ... (S)-α-amino-1H-indole-3-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Description: … It is a precursor of indole alkaloids in plants. ... It can be a precursor to niacin, albeit inefficiently, in mammals. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML ... AMINOMIX 3 SOLÜSYON, 15000 ML …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Description: … It is a precursor of indole alkaloids in plants. ... It can be a precursor to niacin, albeit inefficiently, in mammals. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML ... AMINOMIX 3 SOLÜSYON, 15000 ML …
Aminophenazone
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. The FDA suspended the use of aminophenazone due to its association...
Approved
Withdrawn
Matched Synonyms: … 1,5-Dimethyl-4-dimethylamino-2-phenyl-3-pyrazolone ... 3-Keto-1,5-dimethyl-4-dimethylamino-2-phenyl-2,3-dihydropyrazole ... 4-(Dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … a risk of agranulocytosis. ... Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries ... The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … a risk of agranulocytosis. ... Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries ... The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening …
Matched Categories: … Non COX-2 selective NSAIDS …
Dobutamine
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Synonyms: … (±)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol ... 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol ... 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenylethylamine …
Matched Iupac: … 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol …
Matched Description: … It is proposed as a cardiotonic after myocardial infarction or open heart surgery. ... A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Compounds used in a research, industrial, or household setting …
Matched Products: … DOBUTAMINA 250 MG/20 ML ... STERILE DOBUTAMIN CON. 250 MG/20 ML ... MEKARD 250 MG/20 ML IV INFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, …
Matched Iupac: … 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol …
Matched Description: … It is proposed as a cardiotonic after myocardial infarction or open heart surgery. ... A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Compounds used in a research, industrial, or household setting …
Matched Products: … DOBUTAMINA 250 MG/20 ML ... STERILE DOBUTAMIN CON. 250 MG/20 ML ... MEKARD 250 MG/20 ML IV INFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, …
Perphenazine
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Synonyms: … 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol ... 2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine ... 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … Etrafon A Tab ... Etrafon F Tab ... Apo Peram Tab 3-15 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … โมนาซีน-2 ... โปราซิน 2 ... เพอร์นาซีน 2 มก. …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … Etrafon A Tab ... Etrafon F Tab ... Apo Peram Tab 3-15 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … โมนาซีน-2 ... โปราซิน 2 ... เพอร์นาซีน 2 มก. …
Darifenacin
Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence.
Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention.
It is unknown if M3 receptor selectivity is clinically...
Approved
Investigational
Matched Synonyms: … (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamide …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bortezomib
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid ... N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … PORIX® 3.5 POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... BORTEN® 3.5 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... EGIDON ® 3.5 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … PORIX® 3.5 POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... BORTEN® 3.5 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... EGIDON ® 3.5 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Fluphenazine
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine ... 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Fluphenazine 2 Tab 2mg ... PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Fluphenazine 2 Tab 2mg ... PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Periciazine
Periciazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine...
Approved
Investigational
Matched Synonyms: … 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine ... 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine ... 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Description: … Periciazine is a phenothiazine of the piperidine group. ... It is a sedative phenothiazine with weak antipsychotic properties. ... phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Description: … Periciazine is a phenothiazine of the piperidine group. ... It is a sedative phenothiazine with weak antipsychotic properties. ... phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Tobramycin
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … -(1-4))-2-deoxy-D-streptamine ... 3'-Deoxykanamycin B ... O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 ... -hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol …
Matched Description: … A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a ... ., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive ... A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a …
Matched Mixtures name: … POENTOBRAL F ... GOTABIOTIC(R)F OFTALMICO ... TOBRAMICINA E DESAMETASONE EG …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … TOBEL 20 MG/2 ML AMPUL, 3 ADET ... TOBEL 80 MG/2 ML AMPUL, 3 ADET ... TOBEL 20 MG/2 ML AMPUL, 1 ADET …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 ... -hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol …
Matched Description: … A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a ... ., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive ... A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a …
Matched Mixtures name: … POENTOBRAL F ... GOTABIOTIC(R)F OFTALMICO ... TOBRAMICINA E DESAMETASONE EG …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … TOBEL 20 MG/2 ML AMPUL, 3 ADET ... TOBEL 80 MG/2 ML AMPUL, 3 ADET ... TOBEL 20 MG/2 ML AMPUL, 1 ADET …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with …
Matched Description: … This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE ... 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently …
Matched Description: … This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE ... 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently …
Influenza A virus A/Hong Kong/4801/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Betibeglogene autotemcel
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Description: … [L42940] β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a ... [A251770] Allogeneic hematopoietic-cell transplantation would be a therapeutic option in patients with ... Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q …
Dienogest
Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one ... 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile …
Matched Iupac: … 2-[(10S,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1,6-dien-14-yl] …
Matched Description: … It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination …
Matched Mixtures name: … VELBIENNE® 20 ... VELBIENNE® 20 ... LAFAMME 2/2MG …
Matched Products: … DIENOGEST E ETINILESTRADIOLO DOC ... Aridya 2 mg Tabletten ... DIENOGEST 2 MG …
Matched Iupac: … 2-[(10S,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1,6-dien-14-yl] …
Matched Description: … It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination …
Matched Mixtures name: … VELBIENNE® 20 ... VELBIENNE® 20 ... LAFAMME 2/2MG …
Matched Products: … DIENOGEST E ETINILESTRADIOLO DOC ... Aridya 2 mg Tabletten ... DIENOGEST 2 MG …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza a Virus A/california/7/2009 (H1n1) Live(attenuated) Antigen ... Influenza a virus a/california/7/2009(h1n1) live(attenuated) antigen …
Matched Name: … Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
Matched Products: … Influenza A H1N1 2009 Monovalent Vaccine Live Intranasal …
Matched Name: … Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
Matched Products: … Influenza A H1N1 2009 Monovalent Vaccine Live Intranasal …
Rofecoxib
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Synonyms: … 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone ... 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. ... Rofecoxib is a solid. This compound belongs to the stilbenes. ... These are organic compounds containing a 1,2-diphenylethylene moiety. …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. ... Rofecoxib is a solid. This compound belongs to the stilbenes. ... These are organic compounds containing a 1,2-diphenylethylene moiety. …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] ... and 3 [A19626]. ... When used to treat Hepatitis C virus (HCV) infections, it is always used as a part of combination therapies …
Matched Categories: … Treatments for Hepatitis C …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] ... and 3 [A19626]. ... When used to treat Hepatitis C virus (HCV) infections, it is always used as a part of combination therapies …
Matched Categories: … Treatments for Hepatitis C …
2-mercaptobenzothiazole
Approved
Experimental
Vet approved
Matched Synonyms: … 2-MBT ... 2-Benzothiazolethiol ... Benzothiazole-2-thiol …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Phenobarbital
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Description: … A barbituric acid derivative that acts as a nonselective central nervous system depressant. …
Matched Mixtures name: … Phenaphen No 3 Cap ... Phenaphen No 2 Cap ... Phenaphen No.3 Cap …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Mixtures name: … Phenaphen No 3 Cap ... Phenaphen No 2 Cap ... Phenaphen No.3 Cap …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein ... [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval ... offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib] due to a …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein ... [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval ... offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib] due to a …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Displaying drugs 151 - 175 of 12357 in total