Displaying drugs 176 - 200 of 12570 in total
Oxyphenbutazone
Oxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow suppression.
Approved
Withdrawn
Matched Iupac: … 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione …
Matched Description: … Oxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Description: … Oxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Lindane
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Matched Description: … , and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical ... In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity ... Lindane is still allowed for pharmaceutical use until 2015. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein ... for their B-cells counterparts. ... that is overexpressed in malignant cells and is upregulated by oncogenes. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … DIFOLTA 20 MG/ML SOLUCION PARA INFUSION ... SOLUTION FOR INFUSION 20MG/ML ... Folotyn 20mg/ml Solution for Infusion …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein ... for their B-cells counterparts. ... that is overexpressed in malignant cells and is upregulated by oncogenes. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … DIFOLTA 20 MG/ML SOLUCION PARA INFUSION ... SOLUTION FOR INFUSION 20MG/ML ... Folotyn 20mg/ml Solution for Infusion …
Itraconazole
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Synonyms: … 3H-1,2,4-TRIAZOL-3-ONE, 4-(4-(4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... (SUP 2)-1,2,4-TRIAZOLIN-5-ONE ... (±)-1-SEC-BUTYL-4-(P-(4-(P-(((2R*,4S*)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan …
Matched Description: … First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used ... to treat a variety of infections. ... [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. …
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan …
Matched Description: … First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used ... to treat a variety of infections. ... [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. …
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Influenza A virus A/Victoria/2454/2019 IVR-207 (H1N1) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Victoria/2454/2019 IVR-207 (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Mixtures name: … FLUAD Injektionssuspension in einer Fertigspritze ... Sandovac Injektionssuspension in einer Fertigspritze …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Mixtures name: … FLUAD Injektionssuspension in einer Fertigspritze ... Sandovac Injektionssuspension in einer Fertigspritze …
Clomipramine
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine ... 3-Chloroimipramine …
Matched Iupac: … (3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant ... See toxicity section below for a complete listing of side effects. ... In depressed individuals, clomipramine exerts a positive effect on mood. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antidepressive Agents Indicated for Depression ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … ANAFRANIL SR 75 MG UZATILMIŞ SALIMLI BÖLÜNEBİLİR TABLET, 20 ADET …
Matched Iupac: … (3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant ... See toxicity section below for a complete listing of side effects. ... In depressed individuals, clomipramine exerts a positive effect on mood. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Antidepressive Agents Indicated for Depression ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … ANAFRANIL SR 75 MG UZATILMIŞ SALIMLI BÖLÜNEBİLİR TABLET, 20 ADET …
Menadione
A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Approved
Nutraceutical
Matched Synonyms: … Vitamin K 3 ... 2-Methyl-1,4-naphthochinon ... 2-Methyl-1,4-Naphthalenedione …
Matched Iupac: … 2-methyl-1,4-dihydronaphthalene-1,4-dione …
Matched Description: … to active vitamin K2, menaquinone, after alkylation in vivo. ... A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted …
Matched Mixtures name: … LIBAVIT-K 20 MG AMPUL, 5 ADET …
Matched Products: … วิตามิน เค3 ... VI-PLEX K 10 MG 3 AMPUL ... VI-PLEX K 20 MG 2MLX100 AMPUL …
Matched Iupac: … 2-methyl-1,4-dihydronaphthalene-1,4-dione …
Matched Description: … to active vitamin K2, menaquinone, after alkylation in vivo. ... A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted …
Matched Mixtures name: … LIBAVIT-K 20 MG AMPUL, 5 ADET …
Matched Products: … วิตามิน เค3 ... VI-PLEX K 10 MG 3 AMPUL ... VI-PLEX K 20 MG 2MLX100 AMPUL …
Flotufolastat F-18
Flotufolastat F-18 (18F-rhPSMA-7.3) is an 18F-labeled ligand that targets the prostate-specific membrane antigen (PSMA).[A259846,L46731] In patients with recurrent prostate cancer that require localized treatment, the use of 18F-labeled ligands for positron emission tomography (PET) offers accurate diagnostic imaging. Unlike 68Ga-labeled PSMA-targeting ligands, 18F-labeled compounds targeting this protein have a longer...
Approved
Investigational
Matched Synonyms: … Flotufolastat F 18 …
Matched Name: … Flotufolastat F-18 …
Matched Iupac: … (2S)-2-({[(1S)-1-carboxy-3-{[(1R)-1-carboxy-4-(3-{[(5R)-5-carboxy-5-[(2R)-2-[(4S)-4-carboxy-4-[4,7,10 ... -tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]butanamido]-3-({4-[di-tert-butyl((18F)fluoro) …
Matched Description: … [A259846] In May 2023, the FDA approved the use of flotufolastat F-18 for PET of PSMA-positive lesions ... a high level of accumulation in tumors. ... protein have a longer half-life and can be produced in larger batches. …
Matched Name: … Flotufolastat F-18 …
Matched Iupac: … (2S)-2-({[(1S)-1-carboxy-3-{[(1R)-1-carboxy-4-(3-{[(5R)-5-carboxy-5-[(2R)-2-[(4S)-4-carboxy-4-[4,7,10 ... -tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]butanamido]-3-({4-[di-tert-butyl((18F)fluoro) …
Matched Description: … [A259846] In May 2023, the FDA approved the use of flotufolastat F-18 for PET of PSMA-positive lesions ... a high level of accumulation in tumors. ... protein have a longer half-life and can be produced in larger batches. …
Hetacillin
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Synonyms: … -2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Iupac: … -2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Description: … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused ... Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Iupac: … -2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Description: … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused ... Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Ibrexafungerp
Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Synonyms: … -8- ((2R)-3-METHYLBUTAN-2-YL)-14-(5-(PYRIDIN-4-YL)-1H-1,2,4- TRIAZOL-1-YL)-1,6,6A,7,8,9,10,10A,10B,11,12,12A-DODECAHYDRO ... (1S,4AR,6AS,7R,8R,10AR,10BR,12AR,14R,15R)-15-((2R)- 2-AMINO-2,3,3-TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL …
Matched Iupac: … -[(2R)-3-methylbutan-2-yl]-20-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-17-oxapentacyclo[13.3.3.0^{1,14 ... }.0^{2,11}.0^{5,10}]henicos-2-ene-6-carboxylic acid ... (1R,5S,6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7 …
Matched Description: … approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection ... Similar to echinocandins, ibrexafungerp targets the fungal β-1,3-glucan synthase, which is not present in ... Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Iupac: … -[(2R)-3-methylbutan-2-yl]-20-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-17-oxapentacyclo[13.3.3.0^{1,14 ... }.0^{2,11}.0^{5,10}]henicos-2-ene-6-carboxylic acid ... (1R,5S,6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7 …
Matched Description: … approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection ... Similar to echinocandins, ibrexafungerp targets the fungal β-1,3-glucan synthase, which is not present in ... Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Caspofungin
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Synonyms: … (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans ... -4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline …
Matched Iupac: … (10R,12S)-N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl ... )amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl …
Matched Description: … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts cas: … 179463-17-3 …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CASPOFUNGINA 50 MG/VIAL POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... CASPOVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... CASPOVITAE ® 70 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Iupac: … (10R,12S)-N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl ... )amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl …
Matched Description: … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts cas: … 179463-17-3 …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CASPOFUNGINA 50 MG/VIAL POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... CASPOVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... CASPOVITAE ® 70 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Dexlansoprazole
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated ... [A19566, A19568, A178084, A174244] Dexlansoprazole inhibits the final step in gastric acid production ... address some limitations of the older-generation PPIs, such as short plasma half-life and the need for …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated ... [A19566, A19568, A178084, A174244] Dexlansoprazole inhibits the final step in gastric acid production ... address some limitations of the older-generation PPIs, such as short plasma half-life and the need for …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Zolmitriptan
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Synonyms: … 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one ... (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor ... the current "gold standard" for acute migraine treatment. ... It is currently available in both tablet and nasal spray forms.[L12978] …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 2.5 MG FİLM TABLET, 2 ADET ... MIGTERA 5 MG FİLM TABLET, 3 ADET …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor ... the current "gold standard" for acute migraine treatment. ... It is currently available in both tablet and nasal spray forms.[L12978] …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 2.5 MG FİLM TABLET, 2 ADET ... MIGTERA 5 MG FİLM TABLET, 3 ADET …
Glipizide
Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Synonyms: … 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea ... N-{4-[β-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea …
Matched Iupac: … N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide …
Matched Description: … to control blood sugar levels in patients with type 2 diabetes mellitus. ... , sulfonylureas are more commonly used for early-stage type 2 diabetes when there is no progressed pancreatic ... sulfonylureas, such as [tolbutamide] and [chlorpropamide], second-generation sulfonylureas contain a …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … GLUCOTROL-XL 5 MG TABLET, 20 ADET ... GLUCOTROL-XL 10 MG TABLET, 20 ADET ... GLUCOTROL-XL 2.5 MG TABLET, 20 ADET …
Matched Iupac: … N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide …
Matched Description: … to control blood sugar levels in patients with type 2 diabetes mellitus. ... , sulfonylureas are more commonly used for early-stage type 2 diabetes when there is no progressed pancreatic ... sulfonylureas, such as [tolbutamide] and [chlorpropamide], second-generation sulfonylureas contain a …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … GLUCOTROL-XL 5 MG TABLET, 20 ADET ... GLUCOTROL-XL 10 MG TABLET, 20 ADET ... GLUCOTROL-XL 2.5 MG TABLET, 20 ADET …
Threonine
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Approved
Nutraceutical
Matched Synonyms: … 2-Amino-3-hydroxybutyric acid ... L-2-Amino-3-hydroxybutyric acid …
Matched Iupac: … (2S,3R)-2-amino-3-hydroxybutanoic acid …
Matched Description: … It is found in eggs, milk, gelatin, and other proteins. ... An essential amino acid occurring naturally in the L-form, which is the active form. …
Matched Mixtures name: … Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) ... 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose ... AMINOMIX 3 SOLÜSYON, 1000 ML …
Matched Iupac: … (2S,3R)-2-amino-3-hydroxybutanoic acid …
Matched Description: … It is found in eggs, milk, gelatin, and other proteins. ... An essential amino acid occurring naturally in the L-form, which is the active form. …
Matched Mixtures name: … Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) ... 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose ... AMINOMIX 3 SOLÜSYON, 1000 ML …
Olaparib
Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Synonyms: … 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell ... Canada in April 2016. ... Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and …
Matched Categories: … MATE 2-K Inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell ... Canada in April 2016. ... Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and …
Matched Categories: … MATE 2-K Inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Lormetazepam
Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Synonyms: … 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one ... 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia ... It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … NOCTAMID 2 TABLETTEN ... Sedalor 2 mg/10 ml Injektions-/Infusionslösung …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia ... It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … NOCTAMID 2 TABLETTEN ... Sedalor 2 mg/10 ml Injektions-/Infusionslösung …
Propylthiouracil
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Approved
Investigational
Matched Synonyms: … 4-propyl-2-thiouracil ... 6-propyl-2-thiouracil ... 2-Mercapto-6-propyl-4-pyrimidone …
Matched Iupac: … 6-propyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one …
Matched Description: … A thiourea antithyroid agent. ... It is used in the treatment of hyperthyroidism. …
Matched Products: … PROPYCIL 50 MG TABLET, 20 ADET …
Matched Iupac: … 6-propyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one …
Matched Description: … A thiourea antithyroid agent. ... It is used in the treatment of hyperthyroidism. …
Matched Products: … PROPYCIL 50 MG TABLET, 20 ADET …
Carisoprodol
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … (±)-2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate ... 2-methyl-2-propyltrimethylene carbamate isopropylcarbamate ... N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Description: … for abuse in addition to a low risk of dependence [L5074]. ... This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination ... Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Description: … for abuse in addition to a low risk of dependence [L5074]. ... This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination ... Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant …
Bithionol
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Synonyms: … 2-Hydroxy-3,5-dichlorophenyl sulfide ... 2-Hydroxy-3,5-dichlorophenyl sulphide ... Bis(3,5-dichloro-2-hydroxyphenyl) sulfide …
Matched Iupac: … 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol …
Matched Description: … a potent photosensitizer with the potential to cause serious skin disorders. ... Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be ... Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal …
Matched Categories: … Anti-Acne Preparations for Topical Use …
Matched Iupac: … 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol …
Matched Description: … a potent photosensitizer with the potential to cause serious skin disorders. ... Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be ... Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal …
Matched Categories: … Anti-Acne Preparations for Topical Use …
Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Dapiprazole
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Iupac: … 1-(2-methylphenyl)-4-(2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}ethyl)piperazine …
Matched Description: … It is found in ophthalmic solutions used to reverse mydriasis after an eye examination. …
Matched Iupac: … 1-(2-methylphenyl)-4-(2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}ethyl)piperazine …
Matched Description: … It is found in ophthalmic solutions used to reverse mydriasis after an eye examination. …
Estradiol
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7 …
Matched Description: … Estradiol is a naturally occurring hormone circulating endogenously in females. ... It is commercially available in several hormone therapy products for managing conditions associated with ... [L11485,L11488,L11491, L11494,L11497,L11500,L11503] When used for oral or IM administration, estradiol …
Matched Salts cas: … 35380-71-3 …
Matched Mixtures name: … LAFAMME 2/2MG ... LAFAMME 2/2MG ... FEMOSTON 2/10MG …
Matched Categories: … Hormonal Contraceptives for Systemic Use ... Medications that reduce magnesium levels …
Matched Products: … JUVENUM E ... VIPLEN 2 MG ... POSTMENOP 2 MG …
Matched Description: … Estradiol is a naturally occurring hormone circulating endogenously in females. ... It is commercially available in several hormone therapy products for managing conditions associated with ... [L11485,L11488,L11491, L11494,L11497,L11500,L11503] When used for oral or IM administration, estradiol …
Matched Salts cas: … 35380-71-3 …
Matched Mixtures name: … LAFAMME 2/2MG ... LAFAMME 2/2MG ... FEMOSTON 2/10MG …
Matched Categories: … Hormonal Contraceptives for Systemic Use ... Medications that reduce magnesium levels …
Matched Products: … JUVENUM E ... VIPLEN 2 MG ... POSTMENOP 2 MG …
Clidinium
Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also...
Approved
Matched Synonyms: … 3-(2-Hydroxy-2,2-diphenyl-acetoxy)-1-methyl-1-azonia-bicyclo[2.2.2]octane ... 3-hydroxy-1-methylquinuclidinium benzilate ester …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies ... It is used for the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms ... to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies ... It is used for the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms ... to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Calcium glycerophosphate
Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Iupac: … calcium 2-(phosphonooxy)propane-1,3-diol …
Matched Description: … as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings ... calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and phosphate levels ... It is also present in dental or oral hygiene products due to its cariostatic effects. …
Matched Mixtures name: … Somarexin and C 1000 ... Alsimine W Vitamins A D …
Matched Description: … as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings ... calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and phosphate levels ... It is also present in dental or oral hygiene products due to its cariostatic effects. …
Matched Mixtures name: … Somarexin and C 1000 ... Alsimine W Vitamins A D …
Displaying drugs 176 - 200 of 12570 in total