Displaying drugs 301 - 325 of 11741 in total
Sodium phosphate, dibasic
Approved
Ciltacabtagene autoleucel
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Description: … [L40739] Patient T-cells are reprogrammed with a transgene encoding a specific chimeric antigen receptor ... Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. ... [L40749] There have been a number of treatments developed for multiple myeloma (e.g. …
Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Cefotaxime is a third-generation cephalosporin antibiotic. …
Chenodeoxycholic acid
Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Iupac: … 4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … Chenodeoxycholic acid is a bile acid naturally found in the body. …
Matched Description: … Chenodeoxycholic acid is a bile acid naturally found in the body. …
Ethinylestradiol
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Matched Iupac: … (1R,3aS,3bR,9bS,11aS)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Molsidomine
Molsidomine is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones. Interestingly, it is being studied as being a preventive measure in cerebral infarction .
Approved
Investigational
Matched Description: … Interestingly, it is being studied as being a preventive measure in cerebral infarction [A31932]. …
Dipyridamole
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Matched Description: … A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular …
Pimozide
A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994,...
Approved
Matched Description: … A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. …
Matched Categories: … UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Etomidate
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Approved
Nedaplatin
Nedaplatin is a second generation platinum analog . It is less nephrotoxic than DB00515 but has proven equally effective. It was approved for use in Japan in 1995.
Approved
Investigational
Matched Description: … Nedaplatin is a second generation platinum analog [A20300]. …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Irbesartan
Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Matched Description: … [L7459] Unlike angiotensin converting enzyme inhibitors, ARBs are not associated with a dry cough. ... [L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients …
Matched Mixtures name: … IRBEPREX A® 300/10 MG TABLETAS ... IRBEPREX A® 300/10 MG TABLETAS …
Matched Products: … N/A …
Matched Mixtures name: … IRBEPREX A® 300/10 MG TABLETAS ... IRBEPREX A® 300/10 MG TABLETAS …
Matched Products: … N/A …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Cholic Acid
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem]
Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid...
Approved
Matched Iupac: … 1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. ... acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a …
Matched Description: … A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. ... acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a …
Risperidone
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Iupac: … 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin …
Matched Description: … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of ... [L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold …
Matched Description: … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of ... [L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold …
Nystatin
Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species. It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of Streptomyces noursei, and is closely related to amphotericin...
Approved
Vet approved
Matched Description: … a number of yeasts and fungi, most notably _Candida_ species. ... Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against ... [A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Propylene glycol
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
N,N'-diphenyl-1,4-phenylenediamine
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
4-(Isopropylamino)diphenylamine
4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen. Sensitivity to this compound may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … It is also a known allergen. ... Sensitivity to this compound may be identified with a clinical patch test. ... 4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Polyvinyl alcohol
Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
Approved
Matched Description: … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. ... Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Ethinamate
Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Like many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. Nevertheless, the medication itself is generally no longer effective after using it for greater than 7 days. Structurally, it...
Approved
Illicit
Withdrawn
Matched Description: … Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. ... similar medications, the regular use of ethinamate can result in the development of drug tolerance in a …
Aminoglutethimide
An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale,...
Approved
Investigational
Matched Description: … An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of …
Displaying drugs 301 - 325 of 11741 in total